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TGKTDGRKRRWHQHKVERRNELVDGTIVAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMR FAQTTLIPNMAAALSSNLDGFDLAREIIRVYVETVAAEPEPYRFVMANSSASKSKVIADSERIIARMLAV MLRRRVAEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMTSDELIDYLTMLSWSALCGIVEAGGSLEKF RDQPHPSPIVPPRVDD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4540 | - | - | 100% (227) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_1879 | - | 1e-20 | 30.25% (238) | AsnC family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2529 | - | 4e-09 | 24.59% (183) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0482c | - | 1e-118 | 93.24% (222) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0103 | - | 1e-105 | 83.04% (224) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0472c | - | 1e-118 | 93.24% (222) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02457 | - | 1e-116 | 91.40% (221) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4086 | - | 1e-100 | 81.36% (220) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0797 | - | 1e-128 | 99.56% (227) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4678 | - | 1e-109 | 88.58% (219) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0916 | - | 1e-109 | 88.79% (223) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0865 | - | 1e-108 | 89.30% (215) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. vanbaalenii PYR-1 | Mvan_0805 | - | 1e-108 | 84.14% (227) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0103|M.gilvum_PYR-GCK ----MAQHTSPVAVKTDGRKRRWHQHKVERRNELVDGTLDAIRRLGSNVS
Mvan_0805|M.vanbaalenii_PYR-1 -----------MAAKTDGRKRRWHRHKVERRNELVDGTLEAIRRLGSNVS
MSMEG_0916|M.smegmatis_MC2_155 ----MAQQTPPATVKTDGRKRRWHQHKVERRNELVDGTLEAIRRRGSNVS
TH_0865|M.thermoresistible__bu ----VGQQTPPAAVKMDGRKRRWHQHKVERRNELVDGTLEAIRRRGSNVS
MUL_4540|M.ulcerans_Agy99 -----------MTGKTDGRKRRWHQHKVERRNELVDGTIVAIRRHGRFLS
MMAR_0797|M.marinum_M ----MVERIPAMTGKTDGRKRRWHQHKVERRNELVDGTIVAIRRHGRFLS
Mb0482c|M.bovis_AF2122/97 ----MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLS
Rv0472c|M.tuberculosis_H37Rv ----MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLS
MLBr_02457|M.leprae_Br4923 ----MAEHIPAVAVKTDGRKRRWHQHKVERRNELVDGTIDAIRRQGRFLS
MAV_4678|M.avium_104 ---------------MDGRKRRWHQHKVDRRNELVDGTIDAIRRLGGALS
MAB_4086|M.abscessus_ATCC_1997 MAITVASKTQPAAIKTDGRKRRWHKHKVERRTELVDGTLDAIRHRGRDIS
********:***:**.******: ***: * :*
Mflv_0103|M.gilvum_PYR-GCK MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALTSNL
Mvan_0805|M.vanbaalenii_PYR-1 MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNL
MSMEG_0916|M.smegmatis_MC2_155 MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNL
TH_0865|M.thermoresistible__bu MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSTDL
MUL_4540|M.ulcerans_Agy99 MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNL
MMAR_0797|M.marinum_M MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFAQTTLIPNMAAALSSNL
Mb0482c|M.bovis_AF2122/97 MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADM
Rv0472c|M.tuberculosis_H37Rv MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADM
MLBr_02457|M.leprae_Br4923 MDEIAGKIGVSKTVLYRYFIDKNDLTTAVMMRFAQTTLIPNMAAALSTNL
MAV_4678|M.avium_104 MDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPNMAAALTSGL
MAB_4086|M.abscessus_ATCC_1997 MDEIASDIGVSKTVLYRYFVDKNDLTTAVMTRFAQTTLIPKMAAALSARL
*****..************:********** **:******:* ***:: :
Mflv_0103|M.gilvum_PYR-GCK DGYELTREVIRVYVETVANEPEPYQFVMANNSASKSKAVADSEAIIARML
Mvan_0805|M.vanbaalenii_PYR-1 DGYDLTREIIKVYVETVAAEPEPYRFVMANNSASKSKAVADSETIIARML
MSMEG_0916|M.smegmatis_MC2_155 DGFALTREIIRVYVETVAAEPEPYRFVMANNSASKSKAVADSEQIIARML
TH_0865|M.thermoresistible__bu DGYDLTREIIRVYVETVAAEPEPYRFVMANNSAGKSKVVADSERIIARML
MUL_4540|M.ulcerans_Agy99 DGFDLAREIIRVYVETVAAEPEPYRFVMANSSASKSKVIADSERIIARML
MMAR_0797|M.marinum_M DGFDLAREIIRVYVETVAAEPEPYRFVMANSSASKSKVIADSERIIARML
Mb0482c|M.bovis_AF2122/97 DGFELTREIIRVYVETVAAQPEPYRFVMANSSASKSKVIADSERIIARML
Rv0472c|M.tuberculosis_H37Rv DGFELTREIIRVYVETVAAQPEPYRFVMANSSASKSKVIADSERIIARML
MLBr_02457|M.leprae_Br4923 DGFDLTREIIRVYVKTVAAEPEPYQFVMANSSASKSKVIADSERIIARML
MAV_4678|M.avium_104 DGFDLTREVIRVYVETVANEPEPYRFVMSNSSASKSKVIADSERIIARML
MAB_4086|M.abscessus_ATCC_1997 DGYDLTRTVIKVYVETVAAEPEIYPFVMANSSASRSKAIADSERIIARML
**: *:* :*:***:*** :** * ***:*.**.:**.:**** ******
Mflv_0103|M.gilvum_PYR-GCK AVMLRRRMAAAGMDASGAEPWAFHTVGGVQLATHSWMSNPRMTSDDLIDY
Mvan_0805|M.vanbaalenii_PYR-1 AVMLRRRMVSAGMDTGGAEPWAYHIVGGVQLATHSWMSNPRMTAEELIDY
MSMEG_0916|M.smegmatis_MC2_155 AVMLRRRMAEVGMDTGGVEAWAFHTVGGVQLATHSWMSNPRMTSDELIDY
TH_0865|M.thermoresistible__bu GVMLRRRMAEAGMDTRGVEPWSNLIVGGVQLATHSWMSHPRMTSDELIDY
MUL_4540|M.ulcerans_Agy99 AVMLRRRVAEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMTSDELIDY
MMAR_0797|M.marinum_M AVMLRRRMAEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMTSDELIDY
Mb0482c|M.bovis_AF2122/97 AVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDELIDY
Rv0472c|M.tuberculosis_H37Rv AVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDELIDY
MLBr_02457|M.leprae_Br4923 AVMIRRRMQEAGMDAGGVEPWAYLIVGGVQLATHSWMSDPRMSADELIDY
MAV_4678|M.avium_104 AVLMRRRMQHAGMDTGGVEPWAYLIVGGVQLATHSWMSYPRMSRDELIDY
MAB_4086|M.abscessus_ATCC_1997 ALMLRRRMHEAGMDTHGVEPWAYMIVGGVQLATHSWMSHPRMSSDELIDY
.:::***: .***: *.*.*: ************* ***: ::****
Mflv_0103|M.gilvum_PYR-GCK LTMLSWSALCGIVEVNGSLETFRQNPHPS---------------------
Mvan_0805|M.vanbaalenii_PYR-1 LTMLSWSALCGIVEVNGSLDTFRQSPHPS---------------------
MSMEG_0916|M.smegmatis_MC2_155 LTMLSWYALCGIVEVGGSLEKFNSQPHPS---------------------
TH_0865|M.thermoresistible__bu LTMLSWSALCGIVEVGGSLEKFREMPHPSXXSSSLSGNGLNSPQPWGPSI
MUL_4540|M.ulcerans_Agy99 LTMLSWSALCGIVEAGGSLEKFRDQPHPS---------------------
MMAR_0797|M.marinum_M LTMLSWSALCGIVEAGGSLEKFRDQPHPS---------------------
Mb0482c|M.bovis_AF2122/97 LTMLSWSALCGIVEAGGSLEKFREQPHPS---------------------
Rv0472c|M.tuberculosis_H37Rv LTMLSWSALCGIVEAGGSLEKFREQPHPS---------------------
MLBr_02457|M.leprae_Br4923 LTMLSWNALCGIVEVGGSLEKFRKQPHPS---------------------
MAV_4678|M.avium_104 LTMLSWNALKGIVEVGGSLEKFREEPHPS---------------------
MAB_4086|M.abscessus_ATCC_1997 LTMIAWNALLGIVDVGGSREKFVDMVHPS---------------------
***::* ** ***:..** :.* . ***
Mflv_0103|M.gilvum_PYR-GCK ---------PVLP-------------------SSLLD-------------
Mvan_0805|M.vanbaalenii_PYR-1 ---------PALP-------------------TRLLD-------------
MSMEG_0916|M.smegmatis_MC2_155 ---------PIPP-------------------RHLLD-------------
TH_0865|M.thermoresistible__bu SMPSRTAAPPDIPTVGIANSGAVSKSISVCTERKLADRARKRPEPGIRPG
MUL_4540|M.ulcerans_Agy99 ---------PIVP-------------------PRVDD-------------
MMAR_0797|M.marinum_M ---------PIVP-------------------PRVDD-------------
Mb0482c|M.bovis_AF2122/97 ---------PIVP-------------------AWGQV-------------
Rv0472c|M.tuberculosis_H37Rv ---------PIVP-------------------AWGQV-------------
MLBr_02457|M.leprae_Br4923 ---------PIIP-------------------PRGP--------------
MAV_4678|M.avium_104 ---------PIVP-------------------PREAAL------------
MAB_4086|M.abscessus_ATCC_1997 ---------PIPPP----------------PQTRQTHSA-----------
* *
Mflv_0103|M.gilvum_PYR-GCK -------
Mvan_0805|M.vanbaalenii_PYR-1 -------
MSMEG_0916|M.smegmatis_MC2_155 -------
TH_0865|M.thermoresistible__bu TRNRRRS
MUL_4540|M.ulcerans_Agy99 -------
MMAR_0797|M.marinum_M -------
Mb0482c|M.bovis_AF2122/97 -------
Rv0472c|M.tuberculosis_H37Rv -------
MLBr_02457|M.leprae_Br4923 -------
MAV_4678|M.avium_104 -------
MAB_4086|M.abscessus_ATCC_1997 -------