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SVIAGVFGAVPPHRYSQREITDEIVKFPALREHEEVVRRLHAAAKVNSRHFVLPLQQYHSLTDFGEVNEI FIDKAVQIGCDALLGALDEAGLRPQDIDMIATTTVTGVAVPSLDARIAGRLGLRPDVRRVPLFGLGCAAG AAGVGRLHDYLRGAPDGVAALVSVELCSLTFPTVKPTVSGLVGTAMFGDGAAAVVAVGDRRAERLGATGP DILDSRSRLYPETLHIMGWNIGSAGMQLVMSPELPAVVEKHLADDVTGFLAAHGLTTGDVGAWITHPAGP KVITAIAATLDLPAEAHELTWRSLGEVANLSSASVLHILRDTIAKPPPAGSPALMLAVGPGFGSELVLLR WH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3105 | - | - | 100% (353) | Pks11 protein |
| M. avium 104 | MAV_3110 | - | e-148 | 71.10% (353) | Pks10 protein |
| M. avium 104 | MAV_1280 | - | 4e-91 | 49.86% (353) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1693 | pks11 | 1e-158 | 76.70% (352) | chalcone synthase |
| M. gilvum PYR-GCK | Mflv_5140 | - | 1e-139 | 65.44% (353) | chalcone/stilbene synthase domain-containing protein |
| M. tuberculosis H37Rv | Rv1665 | pks11 | 1e-158 | 76.70% (352) | chalcone synthase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2474 | pks11_1 | 1e-160 | 76.20% (353) | chalcone synthase, Pks11_1 |
| M. smegmatis MC2 155 | MSMEG_0808 | - | 1e-133 | 64.76% (349) | chalcone synthase Pks10 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1656 | pks11 | 1e-159 | 76.20% (353) | chalcone synthase, Pks11 |
| M. vanbaalenii PYR-1 | Mvan_1196 | - | 1e-142 | 66.19% (352) | chalcone/stilbene synthase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5140|M.gilvum_PYR-GCK ---MTDVHTPVSVIAGVQGALPPHRYSQAEVTDAFLAAPAFAEVGDLLRS
Mvan_1196|M.vanbaalenii_PYR-1 ------MNDRISVIAGVQGALPPYRYSQAEITERFVAVPAFAELEDVVRG
MMAR_2474|M.marinum_M ----------MSVIAGVFGALPPHRYSQSEITEAFLEFPGLQEHEEIVRR
MUL_1656|M.ulcerans_Agy99 ----------MSVIAGVFGALPPHRYSQSEITESFLEFPGLQEHEEIVRR
Mb1693|M.bovis_AF2122/97 ----------MSVIAGVFGALPPHRYSQSEITDSFVEFPGLKEHEEIIRR
Rv1665|M.tuberculosis_H37Rv ----------MSVIAGVFGALPPHRYSQSEITDSFVEFPGLKEHEEIIRR
MAV_3105|M.avium_104 ----------MSVIAGVFGAVPPHRYSQREITDEIVKFPALREHEEVVRR
MSMEG_0808|M.smegmatis_MC2_155 MENTAFTPSGTCTIAGVHGVLPPHRYTQAEVTEALLDLPGYADFEGIVRS
..**** *.:**:**:* *:*: :: *. : ::*
Mflv_5140|M.gilvum_PYR-GCK LHTNAKVDARHLVLPLEQYPDLLDFGDANDLYIHHAVELGCQALTAALDE
Mvan_1196|M.vanbaalenii_PYR-1 LHKHAKVDARHFVLPMDRYPTLVDFGETNDLYLEHSLDLACEALTAALDE
MMAR_2474|M.marinum_M MHAAAKVNSRQFVLPIEQYPALTDFGDANEIFIEKAVDLGIEALMGALDE
MUL_1656|M.ulcerans_Agy99 MHAAAKVNSRQFVLPIEQYPALTDFGDTNEIFIEKAVDLGIEALMGALDE
Mb1693|M.bovis_AF2122/97 LHAAAKVNGRHLVLPLQQYPSLTDFGDANEIFIEKAVDLGVEALLGALDD
Rv1665|M.tuberculosis_H37Rv LHAAAKVNGRHLVLPLQQYPSLTDFGDANEIFIEKAVDLGVEALLGALDD
MAV_3105|M.avium_104 LHAAAKVNSRHFVLPLQQYHSLTDFGEVNEIFIDKAVQIGCDALLGALDE
MSMEG_0808|M.smegmatis_MC2_155 LHKSAKVNSRYLTLPLEEYAALDDFGETNGLFIEHATELGCAALTGALDE
:* ***:.* :.**::.* * ***:.* :::.:: ::. ** .***:
Mflv_5140|M.gilvum_PYR-GCK AGLAPSDLDVIMSTTVTGIAVPSLDARIAAKLGLRPDVRRVPLFGLGCVA
Mvan_1196|M.vanbaalenii_PYR-1 AGLGPRDLDMIMTTTVTGIAVPSLDARIADRLGLRPDVRRVPLFGLGCVA
MMAR_2474|M.marinum_M AGLTPQDIDLIITTTVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVA
MUL_1656|M.ulcerans_Agy99 AGLTPQDIDLIITTTVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVA
Mb1693|M.bovis_AF2122/97 ANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVA
Rv1665|M.tuberculosis_H37Rv ANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGCVA
MAV_3105|M.avium_104 AGLRPQDIDMIATTTVTGVAVPSLDARIAGRLGLRPDVRRVPLFGLGCAA
MSMEG_0808|M.smegmatis_MC2_155 AGLRPEDVDLIITTTVTGAVVPSLDARIAGRVGLRPDVRRVPIFGLGCVA
*.* * *:*:* ::**** .********* ::********:*:*****.*
Mflv_5140|M.gilvum_PYR-GCK GAAGIARMHDYLRGAPGHVAALISVELCSLTRPALAPTIGSLVGSALFGD
Mvan_1196|M.vanbaalenii_PYR-1 GAAGIARMHDYLRGAPDHIAALVSVELCSLTYPAVEPTMASLVGSALFGD
MMAR_2474|M.marinum_M GAAGVARLHDYLRGAPDGVAVLIAVELCSLTYPAVKPTVSGIVGTALFGD
MUL_1656|M.ulcerans_Agy99 GAAGVARLHDYLRGAPDGVAVLIAVELCSLTYPAVKPTVSGIVGTALFGD
Mb1693|M.bovis_AF2122/97 GAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSSLVGTALFGD
Rv1665|M.tuberculosis_H37Rv GAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSSLVGTALFGD
MAV_3105|M.avium_104 GAAGVGRLHDYLRGAPDGVAALVSVELCSLTFPTVKPTVSGLVGTAMFGD
MSMEG_0808|M.smegmatis_MC2_155 GAAGVARLNDYLRGAPDKVAVLVSVELCSLTH-KHTPSMPTLVAGALFGD
****:.*:.*******. :*.*::******* *:: :*. *:***
Mflv_5140|M.gilvum_PYR-GCK GAAAVVAVGEERAGHIRASGPDVLDSRSRMYPDSLDIMGWSVNHNGFQLV
Mvan_1196|M.vanbaalenii_PYR-1 GAAAVIAVGAERAETIGATGPEVLDTRSRMYPDSLDTMGWRVGASGFQLI
MMAR_2474|M.marinum_M GAAAVVAVGDRRAEQIRAGGPDILDSRSRLYPESLDIMGWDVGSHGLQLR
MUL_1656|M.ulcerans_Agy99 GAAAVVAVGDRRAEQIRAGGPDILDSRSRLYPESLDIMGWDVGSHGLQLR
Mb1693|M.bovis_AF2122/97 GAAAVVAVGDRRAEQVRAGGPDILDSRSSLYPDSLHIMGWDVGSHGLRLR
Rv1665|M.tuberculosis_H37Rv GAAAVVAVGDRRAEQVRAGGPDILDSRSSLYPDSLHIMGWDVGSHGLRLR
MAV_3105|M.avium_104 GAAAVVAVGDRRAERLGATGPDILDSRSRLYPETLHIMGWNIGSAGMQLV
MSMEG_0808|M.smegmatis_MC2_155 GASAVVAVGAGRAEQLDPIGPDVLDSRSHLYPDSLHAMGWDIGTKGFEIV
**:**:*** ** : . **::**:** :**::*. *** :. *:.:
Mflv_5140|M.gilvum_PYR-GCK LSPELPALIERYLPDDMASFLGEHDLGIGDIATWVSHPGGPKVLEAIASA
Mvan_1196|M.vanbaalenii_PYR-1 LSPNLPELIERYLADDMAGFLGAHDLQIGDIAAWVSHPGGPKVMEAISET
MMAR_2474|M.marinum_M LAPELTNLIEEYLPDDVDAFLAMHDLTKNDIGAWVSHPGGPKVLDAITNS
MUL_1656|M.ulcerans_Agy99 LAPELTNLIEEYLPDDVDAFLAMHDLTKNDIGAWVSHPGGPKVLDAIANS
Mb1693|M.bovis_AF2122/97 LSPDLTNLIERYLANDVTTFLDAHRLTKDDIGAWVSHPGGPKVIDAVATS
Rv1665|M.tuberculosis_H37Rv LSPDLTNLIERYLANDVTTFLDAHRLTKDDIGAWVSHPGGPKVIDAVATS
MAV_3105|M.avium_104 MSPELPAVVEKHLADDVTGFLAAHGLTTGDVGAWITHPAGPKVITAIAAT
MSMEG_0808|M.smegmatis_MC2_155 LSAEVPGFVGRYLGDDVTEFLGEHGVATDDVSAWVSHPGGPKVIEAIIET
::.::. .: .:* :*: ** * : .*:.:*::**.****: *: :
Mflv_5140|M.gilvum_PYR-GCK LDLPDDALELSWRSLAEIGNLSSSSVLHILRDTIAKKPPAATPGLLMAMG
Mvan_1196|M.vanbaalenii_PYR-1 LGLPDDALDLAWRSLAEVGNLSSSSVLHVLRDTRAKKPPAGTPGLLMAMG
MMAR_2474|M.marinum_M LGLPSDALELTWRSLGEIGNLSSASVLHILRDTIAKVPPSGSPGLMLAMG
MUL_1656|M.ulcerans_Agy99 LGLPSDALELTWRSLGEIGNLSSASVLRILRDTIAKVPPSGSPGLMLAMG
Mb1693|M.bovis_AF2122/97 LALPPEALELTWRSLGEIGNLSSASILHILRDTIEKRPPSGSAGLMLAMG
Rv1665|M.tuberculosis_H37Rv LALPPEALELTWRSLGEIGNLSSASILHILRDTIEKRPPSGSAGLMLAMG
MAV_3105|M.avium_104 LDLPAEAHELTWRSLGEVANLSSASVLHILRDTIAKPPPAGSPALMLAVG
MSMEG_0808|M.smegmatis_MC2_155 LDLPSDALDLTWQSLAEVGNLSSSSVLHVLRDTIRKRPPAGTPGVLMAMG
* ** :* :*:*:**.*:.****:*:*::**** * **:.:..:::*:*
Mflv_5140|M.gilvum_PYR-GCK PGFCSELVLLRWH
Mvan_1196|M.vanbaalenii_PYR-1 PGFCSELVLLRWR
MMAR_2474|M.marinum_M PGFCAELVLLRWH
MUL_1656|M.ulcerans_Agy99 PGFCAELVLLRWH
Mb1693|M.bovis_AF2122/97 PGFCTELVLLRWR
Rv1665|M.tuberculosis_H37Rv PGFCTELVLLRWR
MAV_3105|M.avium_104 PGFGSELVLLRWH
MSMEG_0808|M.smegmatis_MC2_155 PGFCSELVLLRWR
*** :*******: