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TGLRGEAAIVGIAELPAERRPTGPPRFTLDQYALLAKLVIEDAGVDPGRVNGLLTHGVAESAMFAPATLC EYLGLACDFGERVDLGGASSAGMVWRAAAAVELGICEAALAVVPGSASVPHSARRPPPEPNWYGASSNNY GSPQAEFEIPYGNVGQNAPYAQIAQRYAAEFGYDPAALAKIAVDQRTNACAHPGAVFFGTPITAADVLDS PMIADPIHMLETVMRVHGGAAVLIANADLARRGRHRPVWIKGFGEHIAFKTPTYAEDLLSTPIARAAERA FAMAGLDRPDVDVASIYDCYTITVLMSLEDAGFCAKGQGMQWIGGHDLTHRGDFPLNTAGGQLSFGQAGM AGGMHHVVDGARQIMGRAGDAQVPGCHTAFVTGNGGIMSEQVALLLQGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3004 | - | - | 100% (400) | nonspecific lipid-transfer protein |
| M. avium 104 | MAV_5265 | - | e-151 | 64.59% (401) | nonspecific lipid-transfer protein |
| M. avium 104 | MAV_1911 | - | 5e-50 | 34.00% (400) | thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 1e-32 | 29.47% (397) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2377 | - | 1e-144 | 62.59% (401) | hypothetical protein Mflv_2377 |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 1e-32 | 29.47% (397) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2051 | - | 2e-40 | 31.49% (397) | hypothetical protein MAB_2051 |
| M. marinum M | MMAR_4250 | ltp2 | 2e-31 | 30.79% (406) | keto acyl-CoA thiolase, Ltp2 |
| M. smegmatis MC2 155 | MSMEG_6561 | - | 1e-145 | 61.85% (401) | nonspecific lipid-transfer protein |
| M. thermoresistible (build 8) | TH_1527 | - | 1e-148 | 64.00% (400) | nonspecific lipid-transfer protein |
| M. ulcerans Agy99 | MUL_0935 | ltp2 | 5e-32 | 30.79% (406) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_4269 | - | 1e-145 | 62.59% (401) | hypothetical protein Mvan_4269 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2377|M.gilvum_PYR-GCK ----MGLRGEAAIVGYVELPPERLNKATPAPFTLEQWAELAAAALEDAGL
Mvan_4269|M.vanbaalenii_PYR-1 ----MGLRGEAAIVGYVELPPERLNKATPAPFTLEQWAELGAAALDDAGL
MSMEG_6561|M.smegmatis_MC2_155 MRPRKGLQGEAAIVGYVELPPERLSTASPAPFTLEQWAQLSAAALDDAGL
TH_1527|M.thermoresistible__bu ----MGLRGEAAIVGFTELPATRQPTG-PLEFNLEQWARLAAAALADAGL
MAV_3004|M.avium_104 ---MTGLRGEAAIVGIAELPAERRPTG-PPRFTLDQYALLAKLVIEDAGV
Mb3570c|M.bovis_AF2122/97 -----MLSGQAAIVGIGATDFSK----NSGRSELRLAAEAVLDALADAGL
Rv3540c|M.tuberculosis_H37Rv -----MLSGQAAIVGIGATDFSK----NSGRSELRLAAEAVLDALADAGL
MMAR_4250|M.marinum_M --MTAPLAGAAAIVGIGQTEFSK----ESGRSELQLACEAVSAALDDAGV
MUL_0935|M.ulcerans_Agy99 --MTAPLAGAAAIVGIGQTEFSK----ESGRSELQLACEAVSAALDDAGV
MAB_2051|M.abscessus_ATCC_1997 -----MPHDQPAIIGAAEVAPGR----NVPYTSTELHVRAAVAALADAGV
. .**:* : .: ***:
Mflv_2377|M.gilvum_PYR-GCK SGEAPDGIVTTH--LNESEIFVPSTVAEYLGV-RAGFAEIVDLGGASAVG
Mvan_4269|M.vanbaalenii_PYR-1 SGELVDGIVTTH--LSESEIFVPSTVTEYLGV-RANFAEMVDLGGASAVG
MSMEG_6561|M.smegmatis_MC2_155 SAEQVDGIVTSH--LGESEIFVPSTVAEYLGV-RANFAELLDLGGASAAG
TH_1527|M.thermoresistible__bu TAADVDGIVTTH--LPESQLFAPSTIIEYLGI-TANFAELVDLGGASSAA
MAV_3004|M.avium_104 DPGRVNGLLTHG--VAESAMFAPATLCEYLGL-ACDFGERVDLGGASSAG
Mb3570c|M.bovis_AF2122/97 SPTDVDGLTTFT--MDTNTEIAVARAAGIG---ELTFFSKIHYGGGAACA
Rv3540c|M.tuberculosis_H37Rv SPTDVDGLTTFT--MDTNTEIAVARAAGIG---ELTFFSKIHYGGGAACA
MMAR_4250|M.marinum_M TPGEVDGMVTFT--MDASDEIDVARNVGIG---DLNFFSRVPHGGGAAAG
MUL_0935|M.ulcerans_Agy99 TPGEVDGMVTFT--MDASDEIDVARNVGIG---DLNFFSRVPHGGGAAAG
MAB_2051|M.abscessus_ATCC_1997 VPDEVDGLVCAGPMTNEGSIFLSEDLMDYLGLHNLKLQMTCQLGGGTHLA
:*: . : : **.: .
Mflv_2377|M.gilvum_PYR-GCK MVWRAAAAIELGICDVVVCAIPARYITPVSEKKPKPLIDAVFFGASSNQY
Mvan_4269|M.vanbaalenii_PYR-1 MVWRAAAAIELGICDVVLCAIPARYLTPTSPKKPKPLVDAVFFGASSNQF
MSMEG_6561|M.smegmatis_MC2_155 MVWRAAAAIELGICDVVLCALPARYLTPMSDLKPKSLSDAVFFGSSSNQF
TH_1527|M.thermoresistible__bu MVWRAAAAIELGLCSAVLCVVPAIPLTPTCEEKPVDFTEMLYFGASSNRY
MAV_3004|M.avium_104 MVWRAAAAVELGICEAALAVVPGSASVPHSARRPP--PEPNWYGASSNNY
Mb3570c|M.bovis_AF2122/97 TVQHAAMAVATGVADVVVAYR------AFNERSGMRFGQVQTRLTENADS
Rv3540c|M.tuberculosis_H37Rv TVQHAAMAVATGVADVVVAYR------AFNERSGMRFGQVQTRLTENADS
MMAR_4250|M.marinum_M TVAHAAMAVATGVAEVVVCYR------AFNERSGMRFGGSGRTSTE----
MUL_0935|M.ulcerans_Agy99 TVAHAAMAVATGVAEVVVCYR------AFNERSGMRFGGSGRTSTE----
MAB_2051|M.abscessus_ATCC_1997 MTRMASNVIARGEAETVLVVS-------------AGKFPPIRDGGRELMA
. *: .: * ....:
Mflv_2377|M.gilvum_PYR-GCK GSPQAEFEIPYGNLGQNGPYGQVAQRYASVYGYDERAMAKIVVDQRVNAN
Mvan_4269|M.vanbaalenii_PYR-1 GSPQAEFEIPYGNLGQNGPYGQVAQRYASVYGYDERAMAKIVVDQRFNAN
MSMEG_6561|M.smegmatis_MC2_155 GSPQAEFDIPYGNLGQNGPYGQVAQRYAYEYGYDERAMAKIVVDQRVNAN
TH_1527|M.thermoresistible__bu GSPQAEFEIPYGNLGQNGPYGQVATRYAATYGYDERAMAKISVDQRVNAN
MAV_3004|M.avium_104 GSPQAEFEIPYGNVGQNAPYAQIAQRYAAEFGYDPAALAKIAVDQRTNAC
Mb3570c|M.bovis_AF2122/97 TGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAA
Rv3540c|M.tuberculosis_H37Rv TGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAA
MMAR_4250|M.marinum_M TPLFMAHYAPFGLLTPAAWVALHAQRYMSTYGVTNEDFGRIAVVDRAHAA
MUL_0935|M.ulcerans_Agy99 TPLFMAHYAPFGLLTPAAWVALHAQRYMSTYGVTNEDFGRIAVVDRAHAA
MAB_2051|M.abscessus_ATCC_1997 LVCDHAFEMPYGPSVP-ALYGLIAQAWMHETGQGKADIAEVTASQDRWAA
. *.* . . * : * :. : . : *
Mflv_2377|M.gilvum_PYR-GCK HTEGAIWK-DKPLTIEEVLASPVIADP-LHMLEIVMPCVGGAAVVVASAE
Mvan_4269|M.vanbaalenii_PYR-1 HTEGAVWK-DKPLTIEDVLASPVIADP-LHMLEIVMPCLGGAAVVVAGAE
MSMEG_6561|M.smegmatis_MC2_155 HTEGAIWK-DKPLTIEDVLASPIIADP-LHMLEIVMPCVGGAAVVVASAD
TH_1527|M.thermoresistible__bu HTPGAIFE-DKPLTIEDVLASPVIAAP-LRLLEIVMPVMGGAAVVIADER
MAV_3004|M.avium_104 AHPGAVFF-GTPITAADVLDSPMIADP-IHMLETVMRVHGGAAVLIANAD
Mb3570c|M.bovis_AF2122/97 NNPKAYFY-GKPITIEDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAA
Rv3540c|M.tuberculosis_H37Rv NNPKAYFY-GKPITIEDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAA
MMAR_4250|M.marinum_M RNPDAWFY-QRPITLADHQNSRWIIEPVLRLLDCCQESDGGVALVVTSTE
MUL_0935|M.ulcerans_Agy99 RNPDAWFY-QRPITLADHQNSRWIIEPVLRLLDCCQESDGGVALVVTSTE
MAB_2051|M.abscessus_ATCC_1997 LNPAAIAHRSQRLTVEDVLASRPIAGP-FHFYHCSIPCEGGGALVLGSAR
* :* : * * * ::: . *. *::: .
Mflv_2377|M.gilvum_PYR-GCK AAARAKNRPVWIKGFGEQVP----FKTPTYAEDLLQTPIV-RAADTAFAM
Mvan_4269|M.vanbaalenii_PYR-1 VAARARNRPVWIKGFGEQVP----YKTPTYAEDLLQTPIA-RAADTAFTM
MSMEG_6561|M.smegmatis_MC2_155 VAAKAKNRPVWVKGFGEHVP----FKTPTYAEDLLDTPMR-RAAETAFTM
TH_1527|M.thermoresistible__bu LARRGRNRPVWVKGFGERVP----YKTPTYAEDLLQTPMI-TAAASAFGM
MAV_3004|M.avium_104 LARRGRHRPVWIKGFGEHIA----FKTPTYAEDLLSTPIA-RAAERAFAM
Mb3570c|M.bovis_AF2122/97 RARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQ
Rv3540c|M.tuberculosis_H37Rv RARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQ
MMAR_4250|M.marinum_M RARDLRQPAAVITAAAQGAAAEGEMMTSYYREDITGLPEMGVVAKRLWRD
MUL_0935|M.ulcerans_Agy99 RARDLRQPAAVIPAAAQRAAAEGEMMTSYYREDITGLPVMGVVAKRLWRD
MAB_2051|M.abscessus_ATCC_1997 RARAGKHRPVHLLGFGEGHTHG--FLTSLARPGRTGAARS---GPMAFER
* :: .. : . .: . .. . . :
Mflv_2377|M.gilvum_PYR-GCK SGLTREQMDMVSIYDCYTITVLLSLEDAGFCDKGKGMEFVSSHDLTFRGD
Mvan_4269|M.vanbaalenii_PYR-1 SGLTRDQMDMVSIYDCYTITVLLSLEDAGFCEKGKGMEFVSQHDLTFRGD
MSMEG_6561|M.smegmatis_MC2_155 SGLGRDQMDMVSIYDCYTITVLLSLEDAGFCEKGKGMAFVSDHDLTFRGD
TH_1527|M.thermoresistible__bu AGLTPQDMDMVSIYDCYTITVLLSLEDAGFCPKGKGMQFVAEHDLTFRGD
MAV_3004|M.avium_104 AGLDRPDVDVASIYDCYTITVLMSLEDAGFCAKGQGMQWIGGHDLTHRGD
Mb3570c|M.bovis_AF2122/97 SGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGR
Rv3540c|M.tuberculosis_H37Rv SGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGR
MMAR_4250|M.marinum_M SGLKPADIQTAFIYDHFTPFVFTQLEELGFCGRGEAKEFATVENLSLGGL
MUL_0935|M.ulcerans_Agy99 SGLKPADIQTAFIYDHFTPFVFTQLEELGFCGRGEAKEFATVENLSLGGL
MAB_2051|M.abscessus_ATCC_1997 SGRAPADIDIALLYDAFASNPAMILEEAGFVKPGGAGDFYRDGRADPGGD
:* ::: . :** :: **: ** * . : *
Mflv_2377|M.gilvum_PYR-GCK FPLNTAGGQLGFGQAGNAGGMHHVCDATRQIMGRAGDAQVERCDRAFVSG
Mvan_4269|M.vanbaalenii_PYR-1 FPLNTAGGQLGFGQAGNAGGMHHVCDATRQIMGRAGEAQVGNCNRAFVSG
MSMEG_6561|M.smegmatis_MC2_155 FPLNTAGGQLGFGQAGLAGGMHHVCDATRQIMERAGAAQVRNCHRAFVSG
TH_1527|M.thermoresistible__bu FPMNTAGGQLGYGQAGLAGGMHHVCDATRQIMGRAGVTQVPDCNRAFVSG
MAV_3004|M.avium_104 FPLNTAGGQLSFGQAGMAGGMHHVVDGARQIMGRAGDAQVPGCHTAFVTG
Mb3570c|M.bovis_AF2122/97 LPINTHGGQLG---EAYIHGMNGIAEGVRQLRG-TSVNPVAGVEHVLVTA
Rv3540c|M.tuberculosis_H37Rv LPINTHGGQLG---EAYIHGMNGIAEGVRQLRG-TSVNPVAGVEHVLVTA
MMAR_4250|M.marinum_M LPINTNGGLLG---EAYIHGMNGITEAVRQVRG-TSYNQVDHVEHVLVTS
MUL_0935|M.ulcerans_Agy99 LPINTNGGLLG---EAYIHGMNGITEAVRQVRG-TSYNQVDHVEHVLVTS
MAB_2051|M.abscessus_ATCC_1997 LPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQVFGADTAFVHS
:*:** ** : . *: : :. *: : * . .:* .
Mflv_2377|M.gilvum_PYR-GCK NGGILSEQTTLVLEGD-
Mvan_4269|M.vanbaalenii_PYR-1 NGGILSEQTTLVLEGD-
MSMEG_6561|M.smegmatis_MC2_155 NGGILSEQTALILEGD-
TH_1527|M.thermoresistible__bu NGGILSEQTTLVLEGD-
MAV_3004|M.avium_104 NGGIMSEQVALLLQGE-
Mb3570c|M.bovis_AF2122/97 GTGVPTSGLILG-----
Rv3540c|M.tuberculosis_H37Rv GTGVPTSGLILG-----
MMAR_4250|M.marinum_M GTGVPTSGLILAPAG--
MUL_0935|M.ulcerans_Agy99 GTGVPTSGLILAPAG--
MAB_2051|M.abscessus_ATCC_1997 YGSMLCSHVSMVMEGAS
.: . :