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GLRGEAAIVGYVELPPERLNKATPAPFTLEQWAELGAAALDDAGLSGELVDGIVTTHLSESEIFVPSTVT EYLGVRANFAEMVDLGGASAVGMVWRAAAAIELGICDVVLCAIPARYLTPTSPKKPKPLVDAVFFGASSN QFGSPQAEFEIPYGNLGQNGPYGQVAQRYASVYGYDERAMAKIVVDQRFNANHTEGAVWKDKPLTIEDVL ASPVIADPLHMLEIVMPCLGGAAVVVAGAEVAARARNRPVWIKGFGEQVPYKTPTYAEDLLQTPIARAAD TAFTMSGLTRDQMDMVSIYDCYTITVLLSLEDAGFCEKGKGMEFVSQHDLTFRGDFPLNTAGGQLGFGQA GNAGGMHHVCDATRQIMGRAGEAQVGNCNRAFVSGNGGILSEQTTLVLEGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4269 | - | - | 100% (402) | hypothetical protein Mvan_4269 |
| M. vanbaalenii PYR-1 | Mvan_0529 | - | 3e-39 | 30.69% (391) | putative nonspecific lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_0899 | - | 2e-32 | 32.02% (356) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 3e-28 | 28.72% (397) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2377 | - | 0.0 | 92.29% (402) | hypothetical protein Mflv_2377 |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 3e-28 | 28.72% (397) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2051 | - | 5e-40 | 30.67% (401) | hypothetical protein MAB_2051 |
| M. marinum M | MMAR_4250 | ltp2 | 5e-29 | 30.15% (398) | keto acyl-CoA thiolase, Ltp2 |
| M. avium 104 | MAV_5265 | - | 0.0 | 85.82% (402) | nonspecific lipid-transfer protein |
| M. smegmatis MC2 155 | MSMEG_6561 | - | 0.0 | 87.78% (401) | nonspecific lipid-transfer protein |
| M. thermoresistible (build 8) | TH_1527 | - | 1e-180 | 76.37% (402) | nonspecific lipid-transfer protein |
| M. ulcerans Agy99 | MUL_0935 | ltp2 | 3e-29 | 29.90% (398) | lipid-transfer protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4269|M.vanbaalenii_PYR-1 ----MGLRGEAAIVGYVELPPERLNKATPAPFTLEQWAELGAAALDDAGL
Mflv_2377|M.gilvum_PYR-GCK ----MGLRGEAAIVGYVELPPERLNKATPAPFTLEQWAELAAAALEDAGL
MSMEG_6561|M.smegmatis_MC2_155 MRPRKGLQGEAAIVGYVELPPERLSTASPAPFTLEQWAQLSAAALDDAGL
MAV_5265|M.avium_104 --MHMGLRGEAAIVGYVELPPERLSKASPAPFVLEQWAELGAAALQDAGL
TH_1527|M.thermoresistible__bu ----MGLRGEAAIVGFTELPATRQPTG-PLEFNLEQWARLAAAALADAGL
Mb3570c|M.bovis_AF2122/97 -----MLSGQAAIVGIGATDFSKNSGR----SELRLAAEAVLDALADAGL
Rv3540c|M.tuberculosis_H37Rv -----MLSGQAAIVGIGATDFSKNSGR----SELRLAAEAVLDALADAGL
MMAR_4250|M.marinum_M --MTAPLAGAAAIVGIGQTEFSKESGR----SELQLACEAVSAALDDAGV
MUL_0935|M.ulcerans_Agy99 --MTAPLAGAAAIVGIGQTEFSKESGR----SELQLACEAVSAALDDAGV
MAB_2051|M.abscessus_ATCC_1997 -----MPHDQPAIIGAAEVAPGRNVPY----TSTELHVRAAVAALADAGV
. .**:* : . . ** ***:
Mvan_4269|M.vanbaalenii_PYR-1 SGELVDGIVTT--HLSESEIFVPSTVTEYLGV-RANFAEMVDLGGASAVG
Mflv_2377|M.gilvum_PYR-GCK SGEAPDGIVTT--HLNESEIFVPSTVAEYLGV-RAGFAEIVDLGGASAVG
MSMEG_6561|M.smegmatis_MC2_155 SAEQVDGIVTS--HLGESEIFVPSTVAEYLGV-RANFAELLDLGGASAAG
MAV_5265|M.avium_104 PGEVVNGIVAS--HLAESEIFVPSTIAEYLGV-GARFAEHVDLGGASAAA
TH_1527|M.thermoresistible__bu TAADVDGIVTT--HLPESQLFAPSTIIEYLGI-TANFAELVDLGGASSAA
Mb3570c|M.bovis_AF2122/97 SPTDVDGLTTF--TMDTNTEIAVARAAGIG---ELTFFSKIHYGGGAACA
Rv3540c|M.tuberculosis_H37Rv SPTDVDGLTTF--TMDTNTEIAVARAAGIG---ELTFFSKIHYGGGAACA
MMAR_4250|M.marinum_M TPGEVDGMVTF--TMDASDEIDVARNVGIG---DLNFFSRVPHGGGAAAG
MUL_0935|M.ulcerans_Agy99 TPGEVDGMVTF--TMDASDEIDVARNVGIG---DLNFFSRVPHGGGAAAG
MAB_2051|M.abscessus_ATCC_1997 VPDEVDGLVCAGPMTNEGSIFLSEDLMDYLGLHNLKLQMTCQLGGGTHLA
:*:. . : : **.: .
Mvan_4269|M.vanbaalenii_PYR-1 MVWRAAAAIELGICDVVLCAIPARYLTPTSPKKPKPLVDAVFFGASSNQF
Mflv_2377|M.gilvum_PYR-GCK MVWRAAAAIELGICDVVVCAIPARYITPVSEKKPKPLIDAVFFGASSNQY
MSMEG_6561|M.smegmatis_MC2_155 MVWRAAAAIELGICDVVLCALPARYLTPMSDLKPKSLSDAVFFGSSSNQF
MAV_5265|M.avium_104 MVWRAAAAIELGICDAVLCALPARYITPSSKKKPRPMVDAMFFGSSSNQY
TH_1527|M.thermoresistible__bu MVWRAAAAIELGLCSAVLCVVPAIPLTPTCEEKPVDFTEMLYFGASSNRY
Mb3570c|M.bovis_AF2122/97 TVQHAAMAVATGVADVVVAYR------AFNERSGMRFGQVQTRLTENADS
Rv3540c|M.tuberculosis_H37Rv TVQHAAMAVATGVADVVVAYR------AFNERSGMRFGQVQTRLTENADS
MMAR_4250|M.marinum_M TVAHAAMAVATGVAEVVVCYR------AFNERSGMRFGGSGRTSTE----
MUL_0935|M.ulcerans_Agy99 TVAHAAMAVATGVAEVVVCYR------AFNERSGMRFGGSGRTSTE----
MAB_2051|M.abscessus_ATCC_1997 MTRMASNVIARGEAETVLVVS-------------AGKFPPIRDGGRELMA
. *: .: * ...*:
Mvan_4269|M.vanbaalenii_PYR-1 GSPQAEFEIPYGNLGQNGPYGQVAQRYASVYGYDERAMAKIVVDQRFNAN
Mflv_2377|M.gilvum_PYR-GCK GSPQAEFEIPYGNLGQNGPYGQVAQRYASVYGYDERAMAKIVVDQRVNAN
MSMEG_6561|M.smegmatis_MC2_155 GSPQAEFDIPYGNLGQNGPYGQVAQRYAYEYGYDERAMAKIVVDQRVNAN
MAV_5265|M.avium_104 GSPQAEFEIPYGNLGQNGPYGQVAQRYAAVYGYDERAMAKIVVDQRVNAN
TH_1527|M.thermoresistible__bu GSPQAEFEIPYGNLGQNGPYGQVATRYAATYGYDERAMAKISVDQRVNAN
Mb3570c|M.bovis_AF2122/97 TGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAA
Rv3540c|M.tuberculosis_H37Rv TGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAA
MMAR_4250|M.marinum_M TPLFMAHYAPFGLLTPAAWVALHAQRYMSTYGVTNEDFGRIAVVDRAHAA
MUL_0935|M.ulcerans_Agy99 TPLFMAHYAPFGLLTPAAWVALHAQRYMSTYGVTNEDFGRIAVVDRAHAA
MAB_2051|M.abscessus_ATCC_1997 LVCDHAFEMPYGPSVP-ALYGLIAQAWMHETGQGKADIAEVTASQDRWAA
. *.* . . * : * . :. : . : *
Mvan_4269|M.vanbaalenii_PYR-1 HTEGAVWK-DKPLTIEDVLASPVIADP-LHMLEIVMPCLGGAAVVVAGAE
Mflv_2377|M.gilvum_PYR-GCK HTEGAIWK-DKPLTIEEVLASPVIADP-LHMLEIVMPCVGGAAVVVASAE
MSMEG_6561|M.smegmatis_MC2_155 HTEGAIWK-DKPLTIEDVLASPIIADP-LHMLEIVMPCVGGAAVVVASAD
MAV_5265|M.avium_104 HTDGAIWR-DTPLTVEDVLASPVIADP-LHMLEIVMPCVGGAAVVVANAD
TH_1527|M.thermoresistible__bu HTPGAIFE-DKPLTIEDVLASPVIAAP-LRLLEIVMPVMGGAAVVIADER
Mb3570c|M.bovis_AF2122/97 NNPKAYFY-GKPITIEDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAA
Rv3540c|M.tuberculosis_H37Rv NNPKAYFY-GKPITIEDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAA
MMAR_4250|M.marinum_M RNPDAWFY-QRPITLADHQNSRWIIEPVLRLLDCCQESDGGVALVVTSTE
MUL_0935|M.ulcerans_Agy99 RNPDAWFY-QRPITLADHQNSRWIIEPVLRLLDCCQESDGGVALVVTSTE
MAB_2051|M.abscessus_ATCC_1997 LNPAAIAHRSQRLTVEDVLASRPIAGP-FHFYHCSIPCEGGGALVLGSAR
. * :*: : * * * ::: . *. *:*: .
Mvan_4269|M.vanbaalenii_PYR-1 VAARARNRPVWIKGFGEQVP----YKTPTYAEDLLQTPIA-RAADTAFTM
Mflv_2377|M.gilvum_PYR-GCK AAARAKNRPVWIKGFGEQVP----FKTPTYAEDLLQTPIV-RAADTAFAM
MSMEG_6561|M.smegmatis_MC2_155 VAAKAKNRPVWVKGFGEHVP----FKTPTYAEDLLDTPMR-RAAETAFTM
MAV_5265|M.avium_104 LAKRARHRPVWVKGFGEHVP----FKTPTYAEDLLRTPIA-AAADTAFAM
TH_1527|M.thermoresistible__bu LARRGRNRPVWVKGFGERVP----YKTPTYAEDLLQTPMI-TAAASAFGM
Mb3570c|M.bovis_AF2122/97 RARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQ
Rv3540c|M.tuberculosis_H37Rv RARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQ
MMAR_4250|M.marinum_M RARDLRQPAAVITAAAQGAAAEGEMMTSYYREDITGLPEMGVVAKRLWRD
MUL_0935|M.ulcerans_Agy99 RARDLRQPAAVIPAAAQRAAAEGEMMTSYYREDITGLPVMGVVAKRLWRD
MAB_2051|M.abscessus_ATCC_1997 RARAGKHRPVHLLGFGEGHTHG--FLTSLARPGRTGAARS---GPMAFER
* :: .. : . .: . .. . . :
Mvan_4269|M.vanbaalenii_PYR-1 SGLTRDQMDMVSIYDCYTITVLLSLEDAGFCEKGKGMEFVSQHDLTFRGD
Mflv_2377|M.gilvum_PYR-GCK SGLTREQMDMVSIYDCYTITVLLSLEDAGFCDKGKGMEFVSSHDLTFRGD
MSMEG_6561|M.smegmatis_MC2_155 SGLGRDQMDMVSIYDCYTITVLLSLEDAGFCEKGKGMAFVSDHDLTFRGD
MAV_5265|M.avium_104 TGLSRAQMDMVSIYDCYTITVLLSLEDAGFCEKGRGMEFVADHDLTFRGD
TH_1527|M.thermoresistible__bu AGLTPQDMDMVSIYDCYTITVLLSLEDAGFCPKGKGMQFVAEHDLTFRGD
Mb3570c|M.bovis_AF2122/97 SGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGR
Rv3540c|M.tuberculosis_H37Rv SGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGR
MMAR_4250|M.marinum_M SGLKPADIQTAFIYDHFTPFVFTQLEELGFCGRGEAKEFATVENLSLGGL
MUL_0935|M.ulcerans_Agy99 SGLKPADIQTAFIYDHFTPFVFTQLEELGFCGRGEAKEFATVENLSLGGL
MAB_2051|M.abscessus_ATCC_1997 SGRAPADIDIALLYDAFASNPAMILEEAGFVKPGGAGDFYRDGRADPGGD
:* ::: . :** :: **: ** * . * *
Mvan_4269|M.vanbaalenii_PYR-1 FPLNTAGGQLGFGQAGNAGGMHHVCDATRQIMGRAGEAQVGNCNRAFVSG
Mflv_2377|M.gilvum_PYR-GCK FPLNTAGGQLGFGQAGNAGGMHHVCDATRQIMGRAGDAQVERCDRAFVSG
MSMEG_6561|M.smegmatis_MC2_155 FPLNTAGGQLGFGQAGLAGGMHHVCDATRQIMERAGAAQVRNCHRAFVSG
MAV_5265|M.avium_104 FPLNTAGGQLGFGQAGLAGGMHHVCDATRQIMGRAGAAQVPDCNRAFVSG
TH_1527|M.thermoresistible__bu FPMNTAGGQLGYGQAGLAGGMHHVCDATRQIMGRAGVTQVPDCNRAFVSG
Mb3570c|M.bovis_AF2122/97 LPINTHGGQLG---EAYIHGMNGIAEGVRQLRG-TSVNPVAGVEHVLVTA
Rv3540c|M.tuberculosis_H37Rv LPINTHGGQLG---EAYIHGMNGIAEGVRQLRG-TSVNPVAGVEHVLVTA
MMAR_4250|M.marinum_M LPINTNGGLLG---EAYIHGMNGITEAVRQVRG-TSYNQVDHVEHVLVTS
MUL_0935|M.ulcerans_Agy99 LPINTNGGLLG---EAYIHGMNGITEAVRQVRG-TSYNQVDHVEHVLVTS
MAB_2051|M.abscessus_ATCC_1997 LPVNTDGGLIRFGHTGTSSGISQILEGYWQLSGRAEGRQVFGADTAFVHS
:*:** ** : . *: : :. *: : * . .:* .
Mvan_4269|M.vanbaalenii_PYR-1 NGGILSEQTTLVLEGD-
Mflv_2377|M.gilvum_PYR-GCK NGGILSEQTTLVLEGD-
MSMEG_6561|M.smegmatis_MC2_155 NGGILSEQTALILEGD-
MAV_5265|M.avium_104 NGGILSEQTTLILEGD-
TH_1527|M.thermoresistible__bu NGGILSEQTTLVLEGD-
Mb3570c|M.bovis_AF2122/97 GTGVPTSGLILG-----
Rv3540c|M.tuberculosis_H37Rv GTGVPTSGLILG-----
MMAR_4250|M.marinum_M GTGVPTSGLILAPAG--
MUL_0935|M.ulcerans_Agy99 GTGVPTSGLILAPAG--
MAB_2051|M.abscessus_ATCC_1997 YGSMLCSHVSMVMEGAS
.: . :