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MATEVLPDAPALRLARRQRALAAMDEHGLDMLVLGRQANIRYVTGAPQLWIAGTRPFGPMCVLVRATGDI YLNSTDDEGVPEEIDHDHLYGLAWNPVTLIDVLRKVEGAESARRVGTDALTPTFAALLPEAFPNAELVDA EPAMRAARRIKTPDEITAMGAALRVAEHGLAAALAELAPGAAERTLAGAMMEAMAAGGVSTPATQDAAWV TSRERPWRRAGSGEVRPGDLVAFAAGALADGYVAEVGRTWPAGDTVGGQVRALFGRSNALYDRMLAACRP GASTGDLLAAYRAVDEPVPPMPVAHGLGLGFDPPVVSETLAAAGERDRMEAGMVLAITGYVWQRGIGAVF RRDTVHITEGGVQVLTASPTWTGPLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2971 | - | - | 100% (376) | peptidase, M24 family protein |
| M. avium 104 | MAV_0892 | - | e-132 | 60.86% (373) | peptidase, M24 family protein |
| M. avium 104 | MAV_0891 | - | 6e-23 | 25.82% (395) | peptidase, M24 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2564c | pepQ | 2e-07 | 22.56% (359) | putative cytoplasmic peptidase PEPQ |
| M. gilvum PYR-GCK | Mflv_2421 | - | 1e-138 | 64.25% (372) | peptidase M24 |
| M. tuberculosis H37Rv | Rv2535c | pepQ | 2e-07 | 22.56% (359) | cytoplasmic peptidase PepQ |
| M. leprae Br4923 | MLBr_00521 | pepQ | 1e-08 | 26.10% (272) | putative cytoplasmic peptidase |
| M. abscessus ATCC 19977 | MAB_2838c | - | 5e-11 | 26.55% (354) | putative cytoplasmic peptidase PepQ |
| M. marinum M | MMAR_4759 | - | 1e-137 | 64.25% (372) | aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_4853 | - | 1e-133 | 64.50% (369) | peptidase, M24 family protein |
| M. thermoresistible (build 8) | TH_2275 | - | 1e-107 | 75.40% (252) | peptidase, M24 family protein |
| M. ulcerans Agy99 | MUL_0330 | - | 1e-135 | 64.25% (372) | aminopeptidase |
| M. vanbaalenii PYR-1 | Mvan_4231 | - | 1e-138 | 64.78% (372) | peptidase M24 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2971|M.avium_104 MATEVLPDAPALRLARRQRALAAMDEHGLDMLVLGRQANIRYVTGAP---
TH_2275|M.thermoresistible__bu MSTEILPDDRALRHARRNRALAQMAEHDLDILVLGRQANVRYVTGAP---
Mflv_2421|M.gilvum_PYR-GCK MGTEIEADGRALRLSRRERALEQMELHDIDILVLGRQANVRYISGAP---
Mvan_4231|M.vanbaalenii_PYR-1 MGTEIEADGRALRFSRRERALAQMEAHDLDMLVLGRQANVRYISGAP---
MSMEG_4853|M.smegmatis_MC2_155 MGIDIEADNRALRVSRRERALAQMEAYDLDVLVLGRQANVRYISGAP---
MMAR_4759|M.marinum_M MSTEVLPDNRALRCGRRQRALEQMAAHDLDVLVLGRQANVRYVSGTP---
MUL_0330|M.ulcerans_Agy99 MSTEVLPDNRALRCGRRQRALEQMAAHDLDVLVLGRQANVRYVSGTP---
Mb2564c|M.bovis_AF2122/97 ----------MTHSQRRDKLKAQIAASGLDAMLISDLINVRYLSGFSGSN
Rv2535c|M.tuberculosis_H37Rv ----------MTHSQRRDKLKAQIAASGLDAMLISDLINVRYLSGFSGSN
MLBr_00521|M.leprae_Br4923 ----------MTHSQRRDNLKSQIATTGLDAMLVTCLINVRYLSGFTGSN
MAB_2838c|M.abscessus_ATCC_199 ----------------------MLRAEDLDALLVTDLINIRYLTGFTGSA
: .:* ::: *:**::* .
MAV_2971|M.avium_104 -QLWIAGTRPFGPMCVLVRATGDIYLNSTDDEGVPEEIDHDHLYGLAWNP
TH_2275|M.thermoresistible__bu -QLWVAGTRPFGPVCAMLRS-GEIHLNSTWDEGIPEEIGHDHLYGLAWNP
Mflv_2421|M.gilvum_PYR-GCK -QLWVVGTRPFGPICEFVRATGEIHLNSTWDEGIPEEIPHENLYGFAWNP
Mvan_4231|M.vanbaalenii_PYR-1 -QLWVVGTRPFGPICEFVRATGEIHLNSTWDEGIPEEIPHQNLYGFAWNP
MSMEG_4853|M.smegmatis_MC2_155 -QLWVVGTRPFGPICTYVRATGEIHLNSTWDEGIPEEIPHENLYGLAWNP
MMAR_4759|M.marinum_M -QLWVAGTRPFGPTCVLVRATGAIHLLSTWDEGVPDDIPHENLYGISWNP
MUL_0330|M.ulcerans_Agy99 -QLWVAGTRPFGPTCVLVRATGAIHLLSTWDEGVPDDIPHENLYGISWNP
Mb2564c|M.bovis_AF2122/97 GALLVFAD----ERDAVLATDGRYRTQAASQAPDLEVAIERAVGRYLAGR
Rv2535c|M.tuberculosis_H37Rv GALLVFAD----ERDAVLATDGRYRTQAASQAPDLEVAIERAVGRYLAGR
MLBr_00521|M.leprae_Br4923 GALLVFAD----ERGAVLATDGRYRTQAAQQVPELEVAIEQSCGRYLAGR
MAB_2838c|M.abscessus_ATCC_199 AALWVAAGDGPEEKATVLCTDGRYRTQAAAQVPDLRALIDR---RYGAAL
* : . : : * :: : .
MAV_2971|M.avium_104 VTLIDVLRKVEGAESARRVGTDALTPTFAALLPEAFPNAELVDAEPAMRA
TH_2275|M.thermoresistible__bu MTLIGVLRGIAGADTARRVGTDALTPSFAQLLPMAFPNAELVDAEPAMRA
Mflv_2421|M.gilvum_PYR-GCK MTLVGILKNIKGADTFRRVGTDALTPTFAKLLPMAFPNAELIDAEQAMQA
Mvan_4231|M.vanbaalenii_PYR-1 MTLVGILQSIKGADTVRRVGTDALTPTFAKLLPMAFPHADLVDAEQAMQA
MSMEG_4853|M.smegmatis_MC2_155 MTLIGVLQNIKGTATARRVGTDALTPTFAKLLPMAFPQAELVDGEQAMRD
MMAR_4759|M.marinum_M MNTISVLERIDGAATARRVGTDALSPVFAQLLPQAFPNAELVDGELAMRA
MUL_0330|M.ulcerans_Agy99 MNTISVLERIDGAATARRVGTDALSPVFAQLLPQAFPNAELVDDELAMRA
Mb2564c|M.bovis_AF2122/97 AGEAGVGKLGFESHVVTVDGLDALAG------ALEGKNTELVRASGTVES
Rv2535c|M.tuberculosis_H37Rv AGEAGVGKLGFESHVVTVDGLDALAG------ALEGKNTELVRASGTVES
MLBr_00521|M.leprae_Br4923 AADDGVCILGFESHVVTVDGLDALTG------ELEGRHTELVRAPGTVEV
MAB_2838c|M.abscessus_ATCC_199 VAHAPAGRAGFESHVVTVDGFDKLAE------AAT--DVELVRAPNRIEK
: * * *: ..:*: :.
MAV_2971|M.avium_104 ARRIKTPDEITAMGAALRVAEHGLAAALAE--LAPGAAERTLAGAMMEAM
TH_2275|M.thermoresistible__bu ARRVKTVEEVRTLGAALRVAEQAVAAAVAE--LRPGVTEKTLAGIMLEAE
Mflv_2421|M.gilvum_PYR-GCK ARRIKTPEEIEALRRALVVAEEGLAAGAAA--LAPGTTENALAGAVLEAE
Mvan_4231|M.vanbaalenii_PYR-1 ARRIKTPEEVQALRRALVVAEEGLAAGVAA--LRPGIAEKALAGAVLEAE
MSMEG_4853|M.smegmatis_MC2_155 ARRIKTPEEIEALRWALSIAEKGLAAGVAE--VHAGTSEQALSGAILEAE
MMAR_4759|M.marinum_M ARRIKTDEEVVALRAAIAVAESGLAAAVAE--LRTGVSEQLLAGVLVEAV
MUL_0330|M.ulcerans_Agy99 ARRIKTDEEEVALRAAIAVAESGLAAAVAE--LRTGVSEQLLAGVLVEAV
Mb2564c|M.bovis_AF2122/97 LREVKDAGELALLRLACEAADAALTDLVARGGLRPGRTERQVSRELEALM
Rv2535c|M.tuberculosis_H37Rv LREVKDAGELALLRLACEAADAALTDLVARGGLRPGRTERQVSRELEALM
MLBr_00521|M.leprae_Br4923 LREVKDAGELALLRLAAEAADAALTELVARGGVRPGLTEREVGRELEGLM
MAB_2838c|M.abscessus_ATCC_199 LREVKDDSEVLLLERACAAADTALAALIETGGIRPGRTEREVARDLENLM
*.:* * : * *: .:: : .* :*. :. :
MAV_2971|M.avium_104 AAGGVSTPATQDAAWVTSRERPWRRAGS-GEVRPGDLVAFAAGALADGYV
TH_2275|M.thermoresistible__bu AAGGVSTPATQDVAWVTSREHPWRRARTDGRVQEGDLVTFAAGVLADGYV
Mflv_2421|M.gilvum_PYR-GCK AAGGVSTPATQDAAWVTSKDHPWRRAGGDGRVRDGDLVAVSAGVLADGYV
Mvan_4231|M.vanbaalenii_PYR-1 AAGGVSTPATQDAAWVTSKEHPWRRSDGDGLVREGDLVAMSAGVLADGYV
MSMEG_4853|M.smegmatis_MC2_155 AAGGVSTPATQDAAWVTSTEHPWRRAEGDGRVRDGDLVALSAGVLADGYV
MMAR_4759|M.marinum_M AAGGVSTPSNQDVAWVTSREHPWRRASGDRRVRSGDLVAFSAGVLAGGYI
MUL_0330|M.ulcerans_Agy99 LAGGVSTPSNQDVAWVTSREHPWRRASGDRRVRSGDLVAFSAGVLAGGYI
Mb2564c|M.bovis_AF2122/97 LDHGADAVSFETIVAAGANSAIPHHRPTDAVLQVGDFVKIDFGALVAGYH
Rv2535c|M.tuberculosis_H37Rv LDHGADAVSFETIVAAGANSAIPHHRPTDAVLQVGDFVKIDFGALVAGYH
MLBr_00521|M.leprae_Br4923 LDHGADALSFETIVAAGPNSAIPHHRPTDTVLAAGDFVKIDFGALVAGYH
MAB_2838c|M.abscessus_ATCC_199 AEHGADGPSFETIVAAGPNSAIPHHRPTGAMLAAGDFVKIDFGALVAGYH
*.. : : . . . . :: : **:* . *.*. **
MAV_2971|M.avium_104 AEVGRTWPAGDTVGGQVRALFGRSNALYDRMLAACRPGASTGDLLAAYRA
TH_2275|M.thermoresistible__bu GEVGRTWPVXX------XTAVG----------VPCRDGAHR-TVVVALQH
Mflv_2421|M.gilvum_PYR-GCK AEVARTLHVGEP-TDAVRALYRRRDDLWDRLIEACRPGRATSGLLDAYEA
Mvan_4231|M.vanbaalenii_PYR-1 AEVARTLYVGDP-TDAVRALYRRRDDLWDRLLQACRPGAPVSSLLDAYGQ
MSMEG_4853|M.smegmatis_MC2_155 AEVARTLYVGEP-TDAVRALYRRRDDLWDRLADACRPGRPTSALLDAYEQ
MMAR_4759|M.marinum_M GEVGRTWPADG--VAGAAPLYQRWAKLWEGLLLACQPGVGAGELLNAYRQ
MUL_0330|M.ulcerans_Agy99 GEVGRTWPADG--VAGAAPLYQRWAKLWDGLLLACQPGAGAGELLNAYRQ
Mb2564c|M.bovis_AF2122/97 SDMTRTFVLGKA-ADWQLEIYQLVAEAQQAGRQALLPGAELRGVDAAARQ
Rv2535c|M.tuberculosis_H37Rv SDMTRTFVLGKA-ADWQLEIYQLVAEAQQAGRQALLPGAELRGVDAAARQ
MLBr_00521|M.leprae_Br4923 SDMTRTFVLGPA-ADWQLEIYQLVADAQRAGRKALRPGANLRDVDAAARQ
MAB_2838c|M.abscessus_ATCC_199 SDMTRTLVLGSA-APWQQEIHELVLTAQAAGRAALAPGASLKNVDAAARD
.:: ** . * : *
MAV_2971|M.avium_104 VDEPVPP-MPVAHGLGLGFDPPVVSETLAAAGERDRMEAGMVLAITGYVW
TH_2275|M.thermoresistible__bu RNLPEPT-VAAAVAVHMQHDLKWLSVRRAAVC------------------
Mflv_2421|M.gilvum_PYR-GCK AGERLPA-MPVAHGLGLGFDPPVVSPSLRASADAENLEAGMVLAVTAYVW
Mvan_4231|M.vanbaalenii_PYR-1 AGEPLPA-MPVAHGLGLGFDPPVVSPNLRATMEAERLEEGMVLAVTAYVW
MSMEG_4853|M.smegmatis_MC2_155 AGEPLPA-MPVAHGLGLGFDPPVVSPALRATADGERFEEGMVLAVTSYVW
MMAR_4759|M.marinum_M AGEPAPP-MPVARGLGMGFDPPVISAQLPATAANDRLEPGMVLAVTGYVW
MUL_0330|M.ulcerans_Agy99 AGEPAPP-MPVARGLGMGFDPTVISAQLPATAANDRLEPGMVLAVTGYVW
Mb2564c|M.bovis_AF2122/97 LIADAGYGEHFGHGLGHGVGLQIHEAPGIGVTSAGTLLAGSVVTVEPGVY
Rv2535c|M.tuberculosis_H37Rv LIADAGYGEHFGHGLGHGVGLQIHEAPGIGVTSAGTLLAGSVVTVEPGVY
MLBr_00521|M.leprae_Br4923 LIVDAGYGQQFSHGLGHGVGLEIHEAPGIGTTSAGTLLAGSVVTVEPGVY
MAB_2838c|M.abscessus_ATCC_199 VITAAGYGENFGHGLGHGVGLQIHEAPGIGSTATGTLLAGSAVTVEPGVY
. .: . . .
MAV_2971|M.avium_104 QRGIGAVFRRDTVHITEGG--------------VQVLTASPTWTGPLP-
TH_2275|M.thermoresistible__bu -------------------------------------------------
Mflv_2421|M.gilvum_PYR-GCK EEGVGAVFTRDAVLITPDG--------------AEILSSAPAYREAVHG
Mvan_4231|M.vanbaalenii_PYR-1 EQGLGGVFTRDAVLITADG--------------AEILSTAPAYGESVHG
MSMEG_4853|M.smegmatis_MC2_155 EAGIGAVFTRDAVVIGADG--------------PDVLTTVPVYGEAVHG
MMAR_4759|M.marinum_M EAGVGAVFGREAVLVNADG--------------PEVLTASPMWQA----
MUL_0330|M.ulcerans_Agy99 EAGVGAVFGREAVLVNADG--------------PEVLTASPMWQA----
Mb2564c|M.bovis_AF2122/97 LPGRGGVRIEDTLVVAG-GTPKMPETAGQT---PELLTRFPKELAIL--
Rv2535c|M.tuberculosis_H37Rv LPGRGGVRIEDTLVVAG-GTPKMPETAGQT---PELLTRFPKELAIL--
MLBr_00521|M.leprae_Br4923 LSGRGGVRIEDTLVVAAKGTSETPITSRPTGFIPELLTRFPKELAIL--
MAB_2838c|M.abscessus_ATCC_199 LPDRGGVRIEDTLVVRP-----------DG---PELLTRFPKELIVID-