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VSGAAGAAAIAGVALSDVGRVDDKGPYELIAQASRRALADAGLTPDDVDGLASTSQGTLPPVDVGEYLGL RPRWIDSTAVGGASWEVMAAHAADAIAAGHADVVLLTYGSTARSDLRKGLRGANINWGARGPLQWEAPYG HTLISKYAMAARRHMFTYGTTIEQLAEVAVSARFNATDNPEAYYREPITIDDVLGGPMIADPFTKLHCCI RSDGGAAAVLVSAERAKDLRSKPVWVLGSAETTSHMLTSQWDDLTVGPAAVSGPLAFARAGVSPSDVDVA EIYDAFTYMLLLTIEDLGFSPKGEGGAFVEKGSLRLGGALPTNTDGGGLSACHPGQRGLFLLVEAARQLR GECGPRQVPDAKIACVSGTGGWFCSSGTMILGAEEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2621 | - | - | 100% (386) | thiolase |
| M. avium 104 | MAV_1911 | - | 0.0 | 93.78% (386) | thiolase |
| M. avium 104 | MAV_0477 | - | 1e-57 | 38.07% (394) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 3e-48 | 34.70% (389) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_1513 | - | 2e-50 | 34.22% (377) | lipid-transfer protein |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 3e-48 | 34.70% (389) | lipid-transfer protein |
| M. leprae Br4923 | MLBr_01158 | fadA4 | 6e-06 | 25.47% (161) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0618 | - | 2e-55 | 36.75% (381) | lipid-transfer protein |
| M. marinum M | MMAR_5027 | ltp2_1 | 1e-48 | 34.39% (378) | acetyl-CoA acetyltransferase (PaaJ-like), Ltp2_1 |
| M. smegmatis MC2 155 | MSMEG_5990 | - | 2e-51 | 34.21% (380) | lipid-transfer protein |
| M. thermoresistible (build 8) | TH_4525 | - | 1e-132 | 60.63% (381) | PUTATIVE thiolase |
| M. ulcerans Agy99 | MUL_4101 | ltp2_1 | 1e-49 | 34.66% (378) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_5253 | - | 2e-52 | 35.81% (377) | lipid-transfer protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2621|M.avium_104 ---MSGAAGAAAIAG--VALSDVGRVDDKGPYELIAQASRRALADAGLTP
TH_4525|M.thermoresistible__bu -----MAAKGVAIVG--VGLSDCGRVPDKTATALMAQAARRAISDAGLHK
Mflv_1513|M.gilvum_PYR-GCK -----MLSGKAAIAG--IGATDFSKNSGRSELRLAAEAVLDALDDAGLTT
Mvan_5253|M.vanbaalenii_PYR-1 -----MLSGKAAIAG--IGATDFSKNSGRSELRLAAEAVLDALDDAGLTP
MSMEG_5990|M.smegmatis_MC2_155 ---MTGLSGKAAIAG--IGATDFSKNSGRSELRLAAECVLDALDDAGLEP
MAB_0618|M.abscessus_ATCC_1997 ---MTGLSGRSAIAG--IGATDFSKKSGRSELRLAAEAVLDALDDAGLSP
Mb3570c|M.bovis_AF2122/97 -----MLSGQAAIVG--IGATDFSKNSGRSELRLAAEAVLDALADAGLSP
Rv3540c|M.tuberculosis_H37Rv -----MLSGQAAIVG--IGATDFSKNSGRSELRLAAEAVLDALADAGLSP
MMAR_5027|M.marinum_M -----MLSGKAAIVG--IGATDFSKNSGRSELRLAAEAVRDALDDAGLSP
MUL_4101|M.ulcerans_Agy99 -----MLSGKAAIVG--IGATDFSKNSGRSELRLAAEAVRDALDDAGLSP
MLBr_01158|M.leprae_Br4923 MTTSVIVTGARTPIGKLMGSLKDFSASDLGAITIAAALKKANVAPSIVQY
: : * :. . . : * : : :
MAV_2621|M.avium_104 DDVDGLASTSQGTLPPVDVGEYLGL-RPRWIDSTAVGGASWEVMAAHAAD
TH_4525|M.thermoresistible__bu NDIDGLGAHGS-LLAPIEVGEYLGL-RPTWVDSTDVGGSSWEVMAQHAVA
Mflv_1513|M.gilvum_PYR-GCK ADVDGLVTFSMDSNLETAVARSTGIGELKFFSQIGYGGGAAAATVQQAAL
Mvan_5253|M.vanbaalenii_PYR-1 SDVDGLVTFTMDSNLETAVARSTGIGDLTFFSQIGYGGGAAAATVQQAAL
MSMEG_5990|M.smegmatis_MC2_155 SDVDGLVTFTMDSNQETAVARSTGIGELKFFSQIGYGGGAAAATVQQAAL
MAB_0618|M.abscessus_ATCC_1997 SDVDGLVTFTMDSNLETAVARATGIGELKFFSQIGYGGGAAAATVQQAAL
Mb3570c|M.bovis_AF2122/97 TDVDGLTTFTMDTNTEIAVARAAGIGELTFFSKIHYGGGAACATVQHAAM
Rv3540c|M.tuberculosis_H37Rv TDVDGLTTFTMDTNTEIAVARAAGIGELTFFSKIHYGGGAACATVQHAAM
MMAR_5027|M.marinum_M ADVDGLTTFTMDTNTEIAVARAAGIGELKFFSKIHYGGGAACATVQHAAM
MUL_4101|M.ulcerans_Agy99 ADVDGLTTFTMDTNTEIAVARAAGIGELKFFSKIHYGGGAACATVQHAAM
MLBr_01158|M.leprae_Br4923 VIIGQVLTAGAGQMPARQAAVAAGIGWDVPALTINKMCLSGLDAIALADQ
:. : : .. *: : *
MAV_2621|M.avium_104 AIAAGHADVVLLT-YGSTARSDLRKGLRGANINWGARG---PLQWEAPYG
TH_4525|M.thermoresistible__bu AIAAGEIDVALLT-YGSTARSDVKRRKRAPAAAMPTGG---AMQYETPYG
Mflv_1513|M.gilvum_PYR-GCK AVATGVAEVVVAY-RAFNERSEHRFGQVMTGLTVNADSRGVEYSWSYPHG
Mvan_5253|M.vanbaalenii_PYR-1 AVATGVAEVVVAY-RAFNERSEHRFGQVMTGLTVNADSRGVEYSWSYPHG
MSMEG_5990|M.smegmatis_MC2_155 AVATGVAEVVVAY-RAFNERSEFRFGQVMTGLTTNADSRGVEYSWSYPHG
MAB_0618|M.abscessus_ATCC_1997 AVAAGVAEVVVAY-RAFNERSEFRFGQVMTGLSSTADSRGVEYSWSYPHG
Mb3570c|M.bovis_AF2122/97 AVATGVADVVVAY-RAFNERSGMRFGQVQTRLTENADSTGVDNSFSYPHG
Rv3540c|M.tuberculosis_H37Rv AVATGVADVVVAY-RAFNERSGMRFGQVQTRLTENADSTGVDNSFSYPHG
MMAR_5027|M.marinum_M AVATGIADVVVAY-RAFNERSGMRFGQVQTRLTENADSTGVDNSFSYPHG
MUL_4101|M.ulcerans_Agy99 AVATGIADVVVAY-RAFNERSDMRFGQVQTRLTENADSTGVDNSFSYPHG
MLBr_01158|M.leprae_Br4923 LIRAGEFDVVVAGGQESMTKAPHLLMDSRSGYKYGDVTIVDHLAYDGLHD
: :* :*.: :: . :. :.
MAV_2621|M.avium_104 -HTLISKYAMAARRHMFTYGTTIEQLAEVAVSARFNATDNPEAYYR-EPI
TH_4525|M.thermoresistible__bu -ATLIAKYAMAARRHMIEYGTTIDQLAEVAVAAHEWAAMNENAFDR-ERL
Mflv_1513|M.gilvum_PYR-GCK LSTPAASVAMIAQRYMHEFGATSADFGVISVADRKHAANNPKAHFYGKPI
Mvan_5253|M.vanbaalenii_PYR-1 LSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPKAHFYGKPI
MSMEG_5990|M.smegmatis_MC2_155 LSTPAASVAMIARRYMHEYGATSADFGVVSVADRKHAANNPKAHFYGKPI
MAB_0618|M.abscessus_ATCC_1997 LSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPKAFFYGKPI
Mb3570c|M.bovis_AF2122/97 LSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYFYGKPI
Rv3540c|M.tuberculosis_H37Rv LSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYFYGKPI
MMAR_5027|M.marinum_M LSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYFYQKPI
MUL_4101|M.ulcerans_Agy99 LSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYFYQKPI
MLBr_01158|M.leprae_Br4923 VFTNQPMGALTEQRNDVEKFTRQEQDEFAARSHQKAAAAWKDGVFADEVV
* . *: :* : : : : : *: .. : :
MAV_2621|M.avium_104 TIDDVLGGPMIADPFTKLHCCIRSDGGAAAVLVSAERAKDLRSKPVWVLG
TH_4525|M.thermoresistible__bu TIEDVAAAPMLADPFTTRHVCLRTDGGGAVVLAGERIARDCAGEPVWILG
Mflv_1513|M.gilvum_PYR-GCK TIEDHQNSRWIAEPLRLLDCCQETDGGVAIVVTTPERARDLKHRPAIIEA
Mvan_5253|M.vanbaalenii_PYR-1 TIEDHQNSRWIAEPLRLLDCCQETDGGVAIVVTTPERAKDLRHRPAVIEA
MSMEG_5990|M.smegmatis_MC2_155 TIEDHQNSRWIAEPLRLLDCCQETDGGVAIVVTTPERAKDLKHRPVTIEA
MAB_0618|M.abscessus_ATCC_1997 TIEDHQNSRMIADPVRLLDCCQESDGGVAIVVTTPERAKDLKNRPVIIEA
Mb3570c|M.bovis_AF2122/97 TIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRPVVIEA
Rv3540c|M.tuberculosis_H37Rv TIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRPVVIEA
MMAR_5027|M.marinum_M TIDDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAERARDLQQRPAIIEA
MUL_4101|M.ulcerans_Agy99 TIDDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAERARDLQQRPAIIEA
MLBr_01158|M.leprae_Br4923 PVSIPQSK---GDSLQFTEDEGIRANTSAESLAGLKPAFRCGGTITPGSA
.:. .:.. . . * :. * . .
MAV_2621|M.avium_104 SAETTSHMLTSQWDDLT-----VGPAAVSGPLAFARAGVSPSDVDVAEIY
TH_4525|M.thermoresistible__bu TASAASHVSMDEWADFT-----TSAAAESGPKAFARAGVTPADIDVCQLY
Mflv_1513|M.gilvum_PYR-GCK AAQGAGADQFTMYSYYREELG-LPEMGLVGRQLWAQSGLTPQDIQTAVLY
Mvan_5253|M.vanbaalenii_PYR-1 AAQGAGADQFTMYSYYRDELG-LPEMGLVGRQLWEQSGLSPEDIQTAILY
MSMEG_5990|M.smegmatis_MC2_155 AAQGSGADQFTMYSYYRDELG-LPEMGLVGRQLWQQSGLTPDDIQTAILY
MAB_0618|M.abscessus_ATCC_1997 AAQGSGEDQFTMYSYYRDELG-LPEMGLVGRQLWDQSGLTPNDIQTAILY
Mb3570c|M.bovis_AF2122/97 AAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADVQTAVLY
Rv3540c|M.tuberculosis_H37Rv AAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADVQTAVLY
MMAR_5027|M.marinum_M ASQGSSPDQYTMVSYYRPELDGLPEMGLVGQQLWQQSGLKPTDIQTAVLY
MUL_4101|M.ulcerans_Agy99 ASQGSSPDQYTMVSYYRPELDGLPEMGLVGQQLWQQSGLKPTDIQTAVLY
MLBr_01158|M.leprae_Br4923 SQISDGAATVVVMNKEKAQQLGLTWLVEIGAHGVVAGPDSTLQSQPANAI
: . * . .. : : .
MAV_2621|M.avium_104 DAFTYMLLLTIEDLGFSPKGEGGAFVEKGSLRLGGALP--TNTDGGGLSA
TH_4525|M.thermoresistible__bu DSFTSTVLLTVEDLGFCAKGEGGPFIASGTLRPDGALP--TNTDGGGLAA
Mflv_1513|M.gilvum_PYR-GCK DHFTPYTLIQLEELGFCGKGEAKDFIAGGAIEIGGRLP--INTHGGQLGE
Mvan_5253|M.vanbaalenii_PYR-1 DHFTPYTLIQLEELGFCGKGEAKDFIAGGAIEIGGRLP--INTHGGQLGE
MSMEG_5990|M.smegmatis_MC2_155 DHFTPYTLLQLEELGFCGKGEAKDFIAGGAIEIGGKLP--INTHGGQLGE
MAB_0618|M.abscessus_ATCC_1997 DHFTPYTLLQLEELGFCGKGEAKDFIANGAIELGGKLP--INTHGGQLGE
Mb3570c|M.bovis_AF2122/97 DHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGRLP--INTHGGQLGE
Rv3540c|M.tuberculosis_H37Rv DHFTPFTLIQLEELGFCGKGEAKDFIADGAIEVGGRLP--INTHGGQLGE
MMAR_5027|M.marinum_M DHFTPFTLIQLEELGFCGKGEAKDFIADGAIELGGRLP--INTHGGQLGE
MUL_4101|M.ulcerans_Agy99 DHFTPFTLIQLEELGFCGKGEAKDFIADGAIELGGRLP--INTHGGQLGE
MLBr_01158|M.leprae_Br4923 KKAVDREGISVEQLDVVEINEAFAAVALASARELGIAPELVNVNGGAIAV
. . : :*:*.. .*. : .: . * * *..** :.
MAV_2621|M.avium_104 CHPGQRGLFLLVEAARQLRGECGPRQVPDAKIACVSGTGGWFCSSGTMIL
TH_4525|M.thermoresistible__bu CHPGMRGMFLMVEAVRQLRGECGPRQVADAELACVHAMGGFFSHSATMIL
Mflv_1513|M.gilvum_PYR-GCK AY--IHGMNGIAEGVRQLRGTSVNQVPDVEHVLVTAGTG---VPTSGLIL
Mvan_5253|M.vanbaalenii_PYR-1 AY--IHGMNGIAEGVRQLRGTSVNQVPDVEHVLVTAGTG---VPTSGLIL
MSMEG_5990|M.smegmatis_MC2_155 AY--IHGMNGIAEGVRQLRGTSVNQVEGVEHVLVTAGTG---VPTSGLIL
MAB_0618|M.abscessus_ATCC_1997 AY--IHGMNGIAEGVRQLRGTSVNQVPNVEHVLVTAGTG---VPTSGLIL
Mb3570c|M.bovis_AF2122/97 AY--IHGMNGIAEGVRQLRGTSVNPVAGVEHVLVTAGTG---VPTSGLIL
Rv3540c|M.tuberculosis_H37Rv AY--IHGMNGIAEGVRQLRGTSVNPVAGVEHVLVTAGTG---VPTSGLIL
MMAR_5027|M.marinum_M AY--IHGMNGIAEGVRQLRGTSVNPVPDVEHVLVTAGTG---VPTSGLIL
MUL_4101|M.ulcerans_Agy99 AY--IHGMNGIAEGVRQLRGTSVNPVPDVEHVLVTAGTG---VPTSGLIL
MLBr_01158|M.leprae_Br4923 GHP----LGMSGARITLHVALELARRGSGYGVAALCGAG---GQGDALIL
: : . : . * :**
MAV_2621|M.avium_104 GAEEP
TH_4525|M.thermoresistible__bu GRDR-
Mflv_1513|M.gilvum_PYR-GCK G----
Mvan_5253|M.vanbaalenii_PYR-1 G----
MSMEG_5990|M.smegmatis_MC2_155 G----
MAB_0618|M.abscessus_ATCC_1997 G----
Mb3570c|M.bovis_AF2122/97 G----
Rv3540c|M.tuberculosis_H37Rv G----
MMAR_5027|M.marinum_M G----
MUL_4101|M.ulcerans_Agy99 G----
MLBr_01158|M.leprae_Br4923 RAV--