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VLNGLSDIRAFFHTNSVPLYFISPTPFNLLGIDRWIRNFFYLTYFDSFEGIHSRVFVPRRRDRIDFDSMG DVCNHLLRDPETLEFIAGRGPGGKACFVMMDEETQALARQAGLQVMHPPVELRNRLGSKTVMTRLADEAG IPSVPHVMGRAGSYQELLTLAQDAGLGDDLVVSIPYGAAGSGTFFVRGQRDWDEHAGDLTAQQEFKVMKR IRNVEVCLEGAVTRHGTVIGPAMTSLVGYPELTPHRGAWCGNDIWREVLPPGQTHAARQMVGKLGDILSR EGYRGYFEVDLLHDLDSDELYLGEVNPRLSGASPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIEGINA RWERGYGEDEVWGQVILAETSPDVELFTATPRTGVWRIDDDGRVSFSRTANDWATLLDGSEAFYMRVAAP GDLRSEGAQLGVLVTRGHLQTDDYRLTERCQRWVKGMKAKFASTPLAPATPIVSRLVARA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2716 | - | - | 100% (480) | biotin carboxylase-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1751 | - | 0.0 | 83.75% (480) | biotin carboxylase-like protein |
| M. gilvum PYR-GCK | Mflv_0222 | - | 9e-07 | 25.81% (217) | ATP-dependent carboxylate-amine ligase domain-containing |
| M. tuberculosis H37Rv | Rv1722 | - | 0.0 | 83.96% (480) | biotin carboxylase-like protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3388 | - | 0.0 | 85.00% (480) | carboxylase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1415 | purT | 2e-06 | 25.70% (284) | PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 PURT |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0685 | - | 7e-06 | 26.42% (212) | ATP-dependent carboxylate-amine ligase domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1751|M.bovis_AF2122/97 ------------MIVPAREPEPQPRRVLNGLSDVRAFFHNNTMPLYFISP
Rv1722|M.tuberculosis_H37Rv ------------MIVPAREPEPQPRRVLNGLSDVRAFFHNNTVPLYFISP
MMAR_3388|M.marinum_M --------------MTAGNPEPKPPRVLNGLSDVRAFFHNNKLPLYFISP
MAV_2716|M.avium_104 --------------------------MLNGLSDIRAFFHTNSVPLYFISP
Mflv_0222|M.gilvum_PYR-GCK ---------------------------------------MTEMETAHEGR
Mvan_0685|M.vanbaalenii_PYR-1 ---------------------------------------MSDTN-----G
TH_1415|M.thermoresistible__bu VTDPATDPTAEQATDPVAEAAGPGGEPKLQAGAPVDDEPAAQAEPARPAR
Mb1751|M.bovis_AF2122/97 TPFNLLGIYRWIRNFFYLTYYDSFEGEHSRVFVPRRRDRRD---------
Rv1722|M.tuberculosis_H37Rv TPFNLLGIYRWIRNFFYLTYYDSFEGEHSRVFVPRRRDRRD---------
MMAR_3388|M.marinum_M TPFNLLGIDRWVRNFFYLTYFDSFEGAHSRVFVPRRRDRRD---------
MAV_2716|M.avium_104 TPFNLLGIDRWIRNFFYLTYFDSFEGIHSRVFVPRRRDRID---------
Mflv_0222|M.gilvum_PYR-GCK TVVLLLGAGERTR-----ELAPAFEHLGAQVVTAD---------------
Mvan_0685|M.vanbaalenii_PYR-1 ETVLLLGAGERSS-----ELALAFRHLGADVVTVS---------------
TH_1415|M.thermoresistible__bu PTVMLLGAGELSR-----ELVLAFQRLGAEVVAVDRYADAPAYPVADRSV
. *** . :*. : *..
Mb1751|M.bovis_AF2122/97 -FDGMGDVCNHLLRDPETLEFIKNRGPGGKACFVMLDEETQALARQAGLE
Rv1722|M.tuberculosis_H37Rv -FDGMGDVCNHLLRDPETLEFIKNRGPGGKACFVMLDEETQALARQAGLE
MMAR_3388|M.marinum_M -FDGMGDVCNHLLRDPETLEFIARRGPGGKACFVMLDGETQALARQAGLE
MAV_2716|M.avium_104 -FDSMGDVCNHLLRDPETLEFIAGRGPGGKACFVMMDEETQALARQAGLQ
Mflv_0222|M.gilvum_PYR-GCK --AAADAQTLTALIEQHAARYVVADLDTAEATNVATTGALHAIADRDDVE
Mvan_0685|M.vanbaalenii_PYR-1 --DHGETQALTALIDERRPRYVVAD-----AATVATD-ALIAVAERDDVE
TH_1415|M.thermoresistible__bu VATMSDADALTAVIEREAPQYVVAE-----STAVAVD-ALIAVAERGSVE
: : . .:: : * *:* : .::
Mb1751|M.bovis_AF2122/97 VMHPPAELRHRLESKIVMTRLADEAGVPSVPHVIGRVSSYDELSALAHGA
Rv1722|M.tuberculosis_H37Rv VMHPPAELRHRLESKIVMTRLADEAGVPSVPHVIGRVSSYDELSALAHGA
MMAR_3388|M.marinum_M VIHPPAELRHRLGSKIVMTRLANEAGVPSVPHLIGRAGSYEELSTLAHDA
MAV_2716|M.avium_104 VMHPPVELRNRLGSKTVMTRLADEAGIPSVPHVMGRAGSYQELLTLAQDA
Mflv_0222|M.gilvum_PYR-GCK VFPTLRSIRFALDGEALRRLAADELGLPTAPFWF--AGTVEELTAIGQHA
Mvan_0685|M.vanbaalenii_PYR-1 VFPTPRATRLSLDGEGLRRLAADELGLPTAPFWF--AGSVEELTAIVAHA
TH_1415|M.thermoresistible__bu VFPTPRAIRLSYDREGLRRLAADELGLPTAPFWF--AGSVEELTAVAQHA
*: . * : : *:* *:*:.*. : ..: :** :: *
Mb1751|M.bovis_AF2122/97 GLGDDLVVEAAYGNAGSATFFVRGLRDWDQCAGGIVGQPEIKVMKRIRNV
Rv1722|M.tuberculosis_H37Rv GLGDDLVVEAAYGNAGSATFFVRGLRDWDQCAGGIVGQPEIKVMKRIRNV
MMAR_3388|M.marinum_M GLGDDLVIEAAYGNAGSATFFVRGERDWDQCAADLVEQPEIKVMKRIRNV
MAV_2716|M.avium_104 GLGDDLVVSIPYGAAGSGTFFVRGQRDWDEHAGDLTAQQEFKVMKRIRNV
Mflv_0222|M.gilvum_PYR-GCK GFP--LVVKPVSGAPGEGESVLLRPEDVEPAWQRAVAAGAPTRRRVIAES
Mvan_0685|M.vanbaalenii_PYR-1 GFP--MVVKPVAAAPGEGESVLLRPDDVEPAWRHATAAGN--LKRVIAET
TH_1415|M.thermoresistible__bu GFP--LVVRPVTGPAGSGQSVLLREDDVEPAWHRAIAAGHFAQNRVMAET
*: :*: . .*.. .: * : : : :
Mb1751|M.bovis_AF2122/97 EVCIEATVTRHGT-VIGPAMTSLVGYPELTPYRGAWCGNDVWR-GALPPA
Rv1722|M.tuberculosis_H37Rv EVCIEATVTRHGT-VIGPAMTSLVGYPELTPYRGAWCGNDVWR-GALPPA
MMAR_3388|M.marinum_M EVCIEGTVTRHGT-VIGPAMTSLVGYPELTPSKGAWCGNDVWR-EVLPPA
MAV_2716|M.avium_104 EVCLEGAVTRHGT-VIGPAMTSLVGYPELTPHRGAWCGNDIWR-EVLPPG
Mflv_0222|M.gilvum_PYR-GCK VVEVDVEVTLLTVRTAGPAGPTVSFCEPIGHHQSPEGSLESWQPQQLSPV
Mvan_0685|M.vanbaalenii_PYR-1 VVEVDFEVTLLTVRTTGAAGPTVHFCEPIGHHQNDDDALESWQPQQLSPT
TH_1415|M.thermoresistible__bu VVEIDYEVTMLTVRTTGPAGPTIRFCEPIGHHHRNGEVLELWQPQQMSPV
* :: ** . . *.* .:: : : : *: :.*
Mb1751|M.bovis_AF2122/97 QTRAAREMVAKLGDVLSREGYRGYFEVDLLHDLDADELYLGEVNPRLSGA
Rv1722|M.tuberculosis_H37Rv QTRAAREMVAKLGDVLSREGYRGYFEVDLLHDLDADELYLGEVNPRLSGA
MMAR_3388|M.marinum_M QTRAAREMVRKLGDVLSREGYRGYFEVDLLHDLDANELYLGEVNPRLSGA
MAV_2716|M.avium_104 QTHAARQMVGKLGDILSREGYRGYFEVDLLHDLDSDELYLGEVNPRLSGA
Mflv_0222|M.gilvum_PYR-GCK ALDSAKSIAARIVNSLGG---RGVFAVELLVRGD--EVYFSDVRPRLQDS
Mvan_0685|M.vanbaalenii_PYR-1 ALDSAKSIAARIVNSLGG---RGVFAVELLVRGD--EVYFSDVRPRLQDS
TH_1415|M.thermoresistible__bu ALDAAKSIAARIVNSLGG---RGVYGVELLVRDD--EVYFSDVRVRPQDT
:*:.:. :: : *. ** : *:** * *:*:.:*. * ..:
Mb1751|M.bovis_AF2122/97 SPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIEAINSRWERGYGEDEVW
Rv1722|M.tuberculosis_H37Rv SPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIEAINSRWERGYGEDEVW
MMAR_3388|M.marinum_M SPMTNLTTEAYADMPLFLFHLLEYMDVEYELDIEEINTRWERGYGEDEVW
MAV_2716|M.avium_104 SPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIEGINARWERGYGEDEVW
Mflv_0222|M.gilvum_PYR-GCK G----LVTLRSQRLSQFELHARAVLGLPVDT-------------------
Mvan_0685|M.vanbaalenii_PYR-1 G----LVTLRSQRLSQFELHARAVLGLPVDT-------------------
TH_1415|M.thermoresistible__bu G----LVTLRSQRLSHFELHARAILGLAVDT-------------------
. *.* :. * :* :.: :
Mb1751|M.bovis_AF2122/97 GQLIMSETSPDLELFTATPRTGMWRLNHDGRVSFARQGNDWATMLDESEA
Rv1722|M.tuberculosis_H37Rv GQLIMSETSPDLELFTATPRTGMWRLNHDGRVSFARQGNDWATMLDESEA
MMAR_3388|M.marinum_M GQLIMSETSPELELFTSTPRTGVWRLHHDGSVSFARQGNDWATLLDESEA
MAV_2716|M.avium_104 GQVILAETSPDVELFTATPRTGVWRIDDDGRVSFSRTANDWATLLDGSEA
Mflv_0222|M.gilvum_PYR-GCK --IMISPGAAEVTCS----------ADADARLVLG-----EALAVAESDV
Mvan_0685|M.vanbaalenii_PYR-1 --IMISPGAVEVSYPDGEGRAV---PDREIRAVLA-----DALAVAESDV
TH_1415|M.thermoresistible__bu --IMISPAAAEVHYGGSEAAWPGGTGGAELTAVLR-----EALSVPESDV
:::: : :: : : * : *:.
Mb1751|M.bovis_AF2122/97 FYMRVAAPGDLRCEGAQLGVLVTRGHLQTDDYQLTERGRRWIDGLKAQFA
Rv1722|M.tuberculosis_H37Rv FYMRVAAPGDLRCEGAQLGVLVTRGHLQTDDYQLTERGRRWIDGLKAQFA
MMAR_3388|M.marinum_M FYMRVAAPGDLRCEGAQLGVLVTRGHLQTDDYQLTERCQRWVKGLKAHFA
MAV_2716|M.avium_104 FYMRVAAPGDLRSEGAQLGVLVTRGHLQTDDYRLTERCQRWVKGMKAKFA
Mflv_0222|M.gilvum_PYR-GCK RVLRSEPP--------VRVSLAT----APDPIVARDRARRVASALRRSV-
Mvan_0685|M.vanbaalenii_PYR-1 RLFPATAAGDDDDVPWLSWSTAT----AQDPIVARDRARRVATAVRRLR-
TH_1415|M.thermoresistible__bu RLFGGPDD-ETDAPHRLGVALAT----APDATAARRQVRQVSTALRRLW-
: .* * : :: .::
Mb1751|M.bovis_AF2122/97 STPLTPAAPIVSRLVARA
Rv1722|M.tuberculosis_H37Rv STPLTPAAPIVSRLVARA
MMAR_3388|M.marinum_M STPLTPAAPIVSRLVARA
MAV_2716|M.avium_104 STPLAPATPIVSRLVARA
Mflv_0222|M.gilvum_PYR-GCK ------------------
Mvan_0685|M.vanbaalenii_PYR-1 ------------------
TH_1415|M.thermoresistible__bu ------------------