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MAELTGKVAFITGAARGQGRAHAVKLASEGADIIALDLCAQIDSVPYPLATPDDMAATVKLVEEAGGRIA TYEADVRDRDAVKAVVRDGTEKFGDRLDIVIANAGIAPMAAADAWQDVIDVNLTGVYNTIDVAMKPMVKF GNGGAIVLTSSVAGLVGIGAPLGGSVGYAAAKHGIVGIMRVYANFLAQYSIRVNSVHPAGVNTPMIDNDF TRSWLDGMAQQSQGGPDMGNALPVQTLEPEDIANAVYWLVSDAARYVTGITLPVDAGFVNKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3996 | - | - | 100% (272) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1904 | - | 1e-78 | 55.91% (279) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 6e-71 | 54.18% (275) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 7e-94 | 63.70% (270) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2750 | - | 7e-94 | 63.70% (270) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 8e-22 | 33.65% (208) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3081 | - | 1e-85 | 59.42% (276) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1965 | fabG | 7e-95 | 61.85% (270) | short chain dehydrogenase |
| M. avium 104 | MAV_3641 | - | 1e-103 | 68.77% (269) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_2687 | - | 1e-103 | 68.75% (272) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3053 | - | 1e-101 | 67.78% (270) | PUTATIVE carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_3392 | fabG | 7e-94 | 61.11% (270) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_2391 | - | 1e-142 | 90.07% (272) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3996|M.gilvum_PYR-GCK MA--------------ELTGKVAFITGAARGQGRAHAVKLASEGADIIAL
Mvan_2391|M.vanbaalenii_PYR-1 MG--------------ELTGKVAFITGAARGQGRAHAVKLASEGADIIAL
MSMEG_2687|M.smegmatis_MC2_155 MSDTAP-----------LSGKVAFITGAARGQGRAEAVRLAADGADIIAV
TH_3053|M.thermoresistible__bu VADRQPGPDLPPGRSDSLRGRVAFITGAARGQGRAHAVRLASEGADVIAV
Mb2771|M.bovis_AF2122/97 ---MIDRP---------LEGKVAFITGAARGLGRAHAVRLAADGANIIAV
Rv2750|M.tuberculosis_H37Rv ---MIDRP---------LEGKVAFITGAARGLGRAHAVRLAADGANIIAV
MAV_3641|M.avium_104 MPRSSEGP---------LTGKVAFITGAARGQGRAHAVRLAADGADIIAV
MMAR_1965|M.marinum_M MSRPLDGP---------LSGRVAFITGAARGQGRAHALRLARDGADVIAV
MUL_3392|M.ulcerans_Agy99 MSRPLDGP---------LSGRVAFITGAARGQGRAHALRLARDGADVIAV
MAB_3081|M.abscessus_ATCC_1997 MG--------------KLDGKVAFITGAARGQGRAHAIKLASEGASIIAV
MLBr_01740|M.leprae_Br4923 MVKTAQY----------FVGKRCFVTGAASGIGRATALRLAAYGAELYLT
: *: .*:**** * *** *::** **.:
Mflv_3996|M.gilvum_PYR-GCK DLCAQIDSVPYPLATPDDMAATVKLVEEAGGRIATYEADVRDRDAVKAVV
Mvan_2391|M.vanbaalenii_PYR-1 DLCAQIDSVPYPLATPEDLAATAKLVEDAGARIVTYQADVRDRDAVKAAV
MSMEG_2687|M.smegmatis_MC2_155 DLCAQIASVPYPLATPDDLATTAELVEKAGGRIVTRQADVRDEPELAAAL
TH_3053|M.thermoresistible__bu DLCDQIASVPYPLAGADDLAETARMVEEAGGRIVARQADVRDRDGLQQAL
Mb2771|M.bovis_AF2122/97 DICEQIASVPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVAL
Rv2750|M.tuberculosis_H37Rv DICEQIASVPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVAL
MAV_3641|M.avium_104 DLCDQIASVPYPLATPEELAATVKLVEDIGSRIVARQADVRDRESLSAAL
MMAR_1965|M.marinum_M DLCDQIASVPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAAL
MUL_3392|M.ulcerans_Agy99 DLCDQIASVPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAAL
MAB_3081|M.abscessus_ATCC_1997 DICAQIPSVEYPMATTEDLDLTVKEVDALGRAISAHETDVRDREALQAAF
MLBr_01740|M.leprae_Br4923 DR------------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAF
* : : *. . * : . . ..
Mflv_3996|M.gilvum_PYR-GCK RDGTEKFGDRLDIVIANAGIAPMA----A-ADAWQDVIDVNLTGVYNTID
Mvan_2391|M.vanbaalenii_PYR-1 RDGTGKLGDRLDIVVANAGIAPMA----S-ADAWQDVIDVNLTGVYNTVD
MSMEG_2687|M.smegmatis_MC2_155 AAGLDEFG-RLDIVVANAGIAPML----SGPEGWRDVIDVNLTGVHHTVE
TH_3053|M.thermoresistible__bu QAGLDELG-RLDIVIANAGIAPLQ----SGPDGWRDVIDVNLTGVHHTVE
Mb2771|M.bovis_AF2122/97 QAGLDEFG-RLDIVVANAGIAMMQ----AGDDGWRDVIDVNLTGVFHTVQ
Rv2750|M.tuberculosis_H37Rv QAGLDEFG-RLDIVVANAGIAMMQ----AGDDGWRDVIDVNLTGVFHTVQ
MAV_3641|M.avium_104 QAGLDEFG-RLDIVVANAGIAPMS----AGDDGWHDVIDVNLTGVYHTIK
MMAR_1965|M.marinum_M QAGIDELG-QVDIVVANAGIAPMQ----SGDDGWRDVIDVNLSGAYYTVE
MUL_3392|M.ulcerans_Agy99 QAGIDELG-QVDIVVANAGIAPMQ----SGDDGWRDVIDVNLSGAYYTVE
MAB_3081|M.abscessus_ATCC_1997 DAGVHDLG-PVDIVVANAGIATLTPE--CGDDGWRDVLDVNLTGVYHTIE
MLBr_01740|M.leprae_Br4923 GADIHARHPSMDIVMNIAGVSVWGTVDRLTHDQWSNVVAINLMGPIHIIE
. :***: **:: : * :*: :** * :.
Mflv_3996|M.gilvum_PYR-GCK VAMKPMVKFGNGGAIVLTSSVAGLVGIGAPLGGSVGYAAAKHGIVGIMRV
Mvan_2391|M.vanbaalenii_PYR-1 VAMKPMVKFGNGGSIVLTSSVAGLIGLGAPIAGSVGYAAAKHGIVGIMRV
MSMEG_2687|M.smegmatis_MC2_155 VAIPTLVEQGDGGAIVLISSVAGLVGIGGGDRGSLGYTAAKHGIVGLMRA
TH_3053|M.thermoresistible__bu VAVPTLVEQGDGGSIVLISSVAGLVGMGGAKPGALGYTAAKHGIVGLMRQ
Mb2771|M.bovis_AF2122/97 VAIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRA
Rv2750|M.tuberculosis_H37Rv VAIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRA
MAV_3641|M.avium_104 VAIPALVKQGTGGSIVLISSSAGLAGVGSADPGSVGYVAAKHGVVGLMRV
MMAR_1965|M.marinum_M VAIPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYAASKHALVGLMRV
MUL_3392|M.ulcerans_Agy99 VAIPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRV
MAB_3081|M.abscessus_ATCC_1997 VARPSMVQRGAGGSIVLTSSVAGLTGMVMDNPGGLAYTAAKHGLVGLMRS
MLBr_01740|M.leprae_Br4923 TFVPAILAAGRGGHLVNVSSAAGLVAL----PWHAAYSASKYGLRGLSEV
. .:: * ** :* ** *** .: .* *:*:.: *: .
Mflv_3996|M.gilvum_PYR-GCK YANFLAQYSIRVNSVHPAGVNTPMID----------NDFTRSWLDGMAQQ
Mvan_2391|M.vanbaalenii_PYR-1 YANFLAQYSIRVNSVHPAAVNTPMID----------NEFTRSWLDGMAQQ
MSMEG_2687|M.smegmatis_MC2_155 YANHLAPHSIRVNSVHPTGVDTPMID----------NEFTRGWLAHITEE
TH_3053|M.thermoresistible__bu YANLLAPHHIRVNSVHPTGVDTPMID----------NEFTRQFLQQVLAE
Mb2771|M.bovis_AF2122/97 YANHLAPQNIRVNSVHPCGVDTPMIN----------NEFFQQWLT--TAD
Rv2750|M.tuberculosis_H37Rv YANHLAPQNIRVNSVHPCGVDTPMIN----------NEFFQQWLT--TAD
MAV_3641|M.avium_104 YANLLAGQMIRVNSIHPSGVETPMIN----------NEFTREWLAKMAAA
MMAR_1965|M.marinum_M YANLLAPHSIRVNSLHPSGVDTPMIN----------NEFIRRWLADLVAE
MUL_3392|M.ulcerans_Agy99 YANLLAPHSIRVNSLHPSGVDPPMIN----------NEFIRHWLADLVAE
MAB_3081|M.abscessus_ATCC_1997 YANMLAPHNIRVNTIHPSGVATPMLI----------NPVTEKLFADGSPE
MLBr_01740|M.leprae_Br4923 LRFDLARYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGH
** * *. : * .* .*:: : .
Mflv_3996|M.gilvum_PYR-GCK SQGGPDMGNALPVQTLE---------------------------PEDIAN
Mvan_2391|M.vanbaalenii_PYR-1 SEGGPDMGNALPVSALE---------------------------PEDIAN
MSMEG_2687|M.smegmatis_MC2_155 TGRPVDMGNALPVQAID---------------------------ADDVAN
TH_3053|M.thermoresistible__bu AQRPMDMGNALPVQAIE---------------------------PEDVAN
Mb2771|M.bovis_AF2122/97 MDAPHNLGNALPVELVQ---------------------------PTDIAN
Rv2750|M.tuberculosis_H37Rv MDAPHNLGNALPVELVQ---------------------------PTDIAN
MAV_3641|M.avium_104 TDTPGAMGNAMPVEVLA---------------------------PEDVAN
MMAR_1965|M.marinum_M TGSGPGAGNALPVQILQ---------------------------ADDIAG
MUL_3392|M.ulcerans_Agy99 TGSGPGAGNALPVQILQ---------------------------ADDIAG
MAB_3081|M.abscessus_ATCC_1997 GMS--DTGNALPVVLME---------------------------PEDMAN
MLBr_01740|M.leprae_Br4923 AVSAERAAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVN
.: : . . ..
Mflv_3996|M.gilvum_PYR-GCK AVYWLVSDAARYVTGITLPVDAGFVNKR----------
Mvan_2391|M.vanbaalenii_PYR-1 AVFWLVSDAARYVTGITLPVDAGYINKR----------
MSMEG_2687|M.smegmatis_MC2_155 AVAWLVSDQARYVTGVTLPVDAGIVNKR----------
TH_3053|M.thermoresistible__bu AVAWLVSDAARYVTGVALPVDAGSVNKR----------
Mb2771|M.bovis_AF2122/97 AVAWLASEEARYVTGVTLPVDAGFVNKR----------
Rv2750|M.tuberculosis_H37Rv AVAWLASEEARYVTGVTLPVDAGFVNKR----------
MAV_3641|M.avium_104 AVAWLVSDQARYITGVTLPVDAGFLNK-----------
MMAR_1965|M.marinum_M ALAWLVSDEARYITGVALPVDAGCVNKR----------
MUL_3392|M.ulcerans_Agy99 ALAWLVSDEARYITGVALPVDAGCVNKR----------
MAB_3081|M.abscessus_ATCC_1997 TVAWLVSEDARYITGVALPVDAGFTNRR----------
MLBr_01740|M.leprae_Br4923 VVFTRALRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
.: . : . *:..* .: