For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTNRWTQRIGDGDPRIGMWVASGSGYVTEICAGSGIDWLLLDQEHAPNDLRSTLGQLQVLAGYPDVDVLV RPPSADPVFIKQLLDIGAQNIIVPMIDGPGEAVAAVSATRYPPNGIRGVGSALARASRWNRISDYLVTAD TAVSLTVQVESVAGLAQLGEITDVDGVDAVFIGPADLAASMGKLGQPEDPDVVSTIETALATIVEHGKRA GVNAFSEPLARRYMAAGASFVLVGADVALLARGTEQLAARYRRQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2618 | - | - | 100% (254) | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
| M. avium 104 | MAV_1907 | - | e-108 | 81.28% (235) | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
| M. avium 104 | MAV_5121 | - | 5e-24 | 29.79% (235) | HpcH/HpaI aldolase/citrate lyase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4105 | - | 1e-23 | 31.58% (247) | HpcH/HpaI aldolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0401 | - | 6e-26 | 30.65% (248) | hypothetical protein MMAR_0401 |
| M. smegmatis MC2 155 | MSMEG_2565 | - | 1e-22 | 30.61% (245) | 4-hydroxy-2-oxovalerate aldolase |
| M. thermoresistible (build 8) | TH_3347 | - | 2e-23 | 30.70% (228) | PUTATIVE putative HpcH/HpaI aldolase |
| M. ulcerans Agy99 | MUL_1051 | - | 4e-24 | 29.84% (248) | hypothetical protein MUL_1051 |
| M. vanbaalenii PYR-1 | Mvan_2241 | - | 6e-21 | 27.31% (249) | HpcH/HpaI aldolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4105|M.gilvum_PYR-GCK --MTSRLQQALSSGGPVWGGWVVGPTVIGPEEYAAAGYDYVGIDVQHSYL
Mvan_2241|M.vanbaalenii_PYR-1 --MASRLQDALADNAQIWGGWVVGPTVLGPEEFAAAGYDYVGFDVQHGYL
MSMEG_2565|M.smegmatis_MC2_155 -MTASRLQQALADRQTVWGGWVVGPTILGPEEFAAAGYDYVGFDVQHGYL
MMAR_0401|M.marinum_M MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYVGFDTQHGYL
MUL_1051|M.ulcerans_Agy99 MKVVSNLQQRLGRGTPLWGGWITGPTWLGPEEFARAGYDYVGFDTQHGYL
TH_3347|M.thermoresistible__bu ------------------MALMHSRTPDVPGLAAAAGYDAVYIDLEHTAT
MAV_2618|M.avium_104 --MTNRWTQRIGDGDPRIGMWVASGSGYVTEICAGSGIDWLLLDQEHAPN
: . : . * :* * : :* :*
Mflv_4105|M.gilvum_PYR-GCK SDADVALMLRRLEHVP-IATVVRLPDAAPAPIGRVLDAGADGVIIAMVES
Mvan_2241|M.vanbaalenii_PYR-1 SDADVALLLRRLEHVP-IATVVRLPGVDAAPIGRVLDAGADGVVIAMVES
MSMEG_2565|M.smegmatis_MC2_155 DDADVALLLRRLEHVP-IATAVRLPSPDPAPIGRVLDAGADAVIIAMVET
MMAR_0401|M.marinum_M DDADVAGLLRRLEGVP-IATVVRLPNADPAPIGRVLDAGADAVIIAMIES
MUL_1051|M.ulcerans_Agy99 DDADVAGLLRRLEGVP-IATVVRLPNADPGPIGRVLDAGADAVIIAMIES
TH_3347|M.thermoresistible__bu PLETVAMLCAAAAGAD-ISALVRVPSHDPSVIARVLDIGAVGVIVPHVNS
MAV_2618|M.avium_104 DLRSTLGQLQVLAGYPDVDVLVRPPSADPVFIKQLLDIGAQNIIVPMIDG
. : . ** *. . * ::** ** :::. ::
Mflv_4105|M.gilvum_PYR-GCK AADAAAAVAATRYAPGGVRSFGPLRASLGLDP-------SALQERASVFA
Mvan_2241|M.vanbaalenii_PYR-1 AAQAAAAVAATRYAPGGVRSFGPLRAGLGIEP-------AALQARASVFA
MSMEG_2565|M.smegmatis_MC2_155 PEQAAAALAATRYAPEGVRSFGPLRASLGHDT-------VALQERASVIA
MMAR_0401|M.marinum_M AEQAAAAVAATRYPPAGVRSYGPLRASLGTDP-------AELQSRAGVYA
MUL_1051|M.ulcerans_Agy99 AEQAAAAVAATRYPPAGVRSYGPLRASLGTDP-------AELQSRAGVYA
TH_3347|M.thermoresistible__bu KSEAESVVHSARFPPAGRRSISGPNPVTGFRPRTAPELAAEIDRYTVVAA
MAV_2618|M.avium_104 PGEAVAAVSATRYPPNGIRGVGSALARASRWN-RISDYLVTADTAVSLTV
:* :.: ::*:.* * *. . . . : . : .
Mflv_4105|M.gilvum_PYR-GCK MIETTRGLAAVDEICRVDGLTGIYVGPADLAISMGHGPTDAWSRRDVFDV
Mvan_2241|M.vanbaalenii_PYR-1 MVETARGLAAIDEICRVEGLTGIYVGPADLAISLGHGPTEAWTRPDVLNA
MSMEG_2565|M.smegmatis_MC2_155 MIETATGVAAVQDIAAVAGLTGLYVGPADLAISMGNQPTDAWTHPDVLAA
MMAR_0401|M.marinum_M MVETAAALSTIDDICAVDGLAGIYVGPADLAISLGTGVVGALDHPAVRQA
MUL_1051|M.ulcerans_Agy99 MVETAAAVSTIDDICAVDGPAGIYVGPADLAISLGTGVVGALDHAAVRQA
TH_3347|M.thermoresistible__bu MVETPQAVESVDDIAAVAGLDMILLGPSDLTAEMG--IHGDFENHRFHEA
MAV_2618|M.avium_104 QVESVAGLAQLGEITDVDGVDAVFIGPADLAASMG--KLGQPEDPDVVST
:*: .: : :* * * : :**:**: .:* . .
Mflv_4105|M.gilvum_PYR-GCK ILTAQRAAAAAGVVSGIHAS-AGSAGNMLAQNGFQMITLASESQALRRGA
Mvan_2241|M.vanbaalenii_PYR-1 MQHLQRTAAKAGLVTGIHAN-TGTIGNAMAQKGFQMITLASESQALRRGA
MSMEG_2565|M.smegmatis_MC2_155 FVTVRQAADAAGLAGGIHAG-TGRAGKAAADMGFRMITLASESQALRRGA
MMAR_0401|M.marinum_M VVGIHRAASAASLHTGIHAG-AAKAGKAMAQLGFEMITLAAESQALRRGA
MUL_1051|M.ulcerans_Agy99 VVGIHRAASAANLHTGIHAG-AAKAGKAMAQLGFEMITLAAESQALRRGA
TH_3347|M.thermoresistible__bu VGAVAEACREHGVAFGIAGIRSPDLLAHFVDLGLRFISAGTDVGMLTDAA
MAV_2618|M.avium_104 IETALATIVEHGKRAGVNAF-SEPLARRYMAAGASFVLVGADVALLARGT
. : . *: . : * :: .:: * .:
Mflv_4105|M.gilvum_PYR-GCK AAHLSDARGES---GDGR--
Mvan_2241|M.vanbaalenii_PYR-1 AAHLAEATGQSVAPGQQRYC
MSMEG_2565|M.smegmatis_MC2_155 VEHLDEATGAGGGHEQRGYL
MMAR_0401|M.marinum_M AEYLNEATAGTR--------
MUL_1051|M.ulcerans_Agy99 AEYLNEATAGTR--------
TH_3347|M.thermoresistible__bu SARARELRALHRSHRT----
MAV_2618|M.avium_104 EQLAARYRRQ----------