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SAAADLVGLGMTAMSLRPGATPLELAVKASAAALADAGLERADIDGILVGSSQGVRPERLGVGFAAAAGF SDLRLLEHVEIKGATTIAMIQRACHAILTAEAATILCVFADAPLVAGRGAGSTYAHSGGNAGVRGLERAS GLLGSVPTYALLTQRWLHVTGTRTDALRSVATTARAWACGNPDAVNREPLDDAGYDSSPMVAEPLRLLDC ARPVNGAVAVVLTGRPSVGGTRLRVRGTGRDHPVRRRRSGAESWFGGGGRAVQDALEQAGMARSDLHVAE LYDPFSIVTLVLLDEYRLTGDIPAGAFVRDGHTGPGGTLPTNTGGGQLSGFYLQGMTPLAEAMIQLRGTG GQRQVPGATVALVGGIGGRMDHHAALVLERAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2614 | - | - | 100% (383) | thiolase |
| M. avium 104 | MAV_1903 | - | 0.0 | 89.01% (382) | thiolase |
| M. avium 104 | MAV_2630 | - | 1e-38 | 33.16% (392) | thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 1e-36 | 30.25% (367) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_1513 | - | 1e-36 | 30.95% (378) | lipid-transfer protein |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 2e-36 | 30.25% (367) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 2e-35 | 29.63% (378) | lipid-transfer protein |
| M. marinum M | MMAR_5027 | ltp2_1 | 5e-37 | 30.62% (369) | acetyl-CoA acetyltransferase (PaaJ-like), Ltp2_1 |
| M. smegmatis MC2 155 | MSMEG_5990 | - | 1e-34 | 30.05% (376) | lipid-transfer protein |
| M. thermoresistible (build 8) | TH_2985 | - | 3e-40 | 32.98% (373) | PUTATIVE putative nonspecific lipid-transfer protein |
| M. ulcerans Agy99 | MUL_4101 | ltp2_1 | 2e-36 | 30.89% (369) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_4311 | - | 1e-59 | 37.76% (384) | hypothetical protein Mvan_4311 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0618|M.abscessus_ATCC_1997 MTGLSGR--SAIAGIGATDFSKKSG---RSELRLAAEAVLDALDDAGLSP
MSMEG_5990|M.smegmatis_MC2_155 MTGLSGK--AAIAGIGATDFSKNSG---RSELRLAAECVLDALDDAGLEP
Mflv_1513|M.gilvum_PYR-GCK --MLSGK--AAIAGIGATDFSKNSG---RSELRLAAEAVLDALDDAGLTT
Mb3570c|M.bovis_AF2122/97 --MLSGQ--AAIVGIGATDFSKNSG---RSELRLAAEAVLDALADAGLSP
Rv3540c|M.tuberculosis_H37Rv --MLSGQ--AAIVGIGATDFSKNSG---RSELRLAAEAVLDALADAGLSP
MMAR_5027|M.marinum_M --MLSGK--AAIVGIGATDFSKNSG---RSELRLAAEAVRDALDDAGLSP
MUL_4101|M.ulcerans_Agy99 --MLSGK--AAIVGIGATDFSKNSG---RSELRLAAEAVRDALDDAGLSP
TH_2985|M.thermoresistible__bu VTHSNGLRDVAIVGIGATPYYKRGGSVPKTTTELACEAIIAACEDAGLSV
MAV_2614|M.avium_104 ----MS-AAADLVGLGMTAMSLRPG---ATPLELAVKASAAALADAGLER
Mvan_4311|M.vanbaalenii_PYR-1 ----MSDPTPAIAGLGITEQGKVYG---RTARQFAAQAVRLAAADAGIEM
. :.*:* * * : .:* :. * ***:
MAB_0618|M.abscessus_ATCC_1997 SDVDGLVTFTMDSN------LETAVARATGIGELKFFSQIGYGGGAAAAT
MSMEG_5990|M.smegmatis_MC2_155 SDVDGLVTFTMDSN------QETAVARSTGIGELKFFSQIGYGGGAAAAT
Mflv_1513|M.gilvum_PYR-GCK ADVDGLVTFSMDSN------LETAVARSTGIGELKFFSQIGYGGGAAAAT
Mb3570c|M.bovis_AF2122/97 TDVDGLTTFTMDTN------TEIAVARAAGIGELTFFSKIHYGGGAACAT
Rv3540c|M.tuberculosis_H37Rv TDVDGLTTFTMDTN------TEIAVARAAGIGELTFFSKIHYGGGAACAT
MMAR_5027|M.marinum_M ADVDGLTTFTMDTN------TEIAVARAAGIGELKFFSKIHYGGGAACAT
MUL_4101|M.ulcerans_Agy99 ADVDGLTTFTMDTN------TEIAVARAAGIGELKFFSKIHYGGGAACAT
TH_2985|M.thermoresistible__bu HDIDGFAYYSGASAGYTEKMDTADFMETLGIPEVRFTAALTSGGGGSAGA
MAV_2614|M.avium_104 ADIDGILVGSSQGVRP--ERLGVGFAAAAGFSDLRLLEHVEIKGATTIAM
Mvan_4311|M.vanbaalenii_PYR-1 ADIDGLIVSG--GIK---ARIGINLQNALGLVDLKLLTEMQGFGSTAAQM
*:**: . : *: :: : : *. :
MAB_0618|M.abscessus_ATCC_1997 VQQAALAVAAGVAEVVVAYRAFNERSEFRFGQVMTGLSSTADSRGVEYSW
MSMEG_5990|M.smegmatis_MC2_155 VQQAALAVATGVAEVVVAYRAFNERSEFRFGQVMTGLTTNADSRGVEYSW
Mflv_1513|M.gilvum_PYR-GCK VQQAALAVATGVAEVVVAYRAFNERSEHRFGQVMTGLTVNADSRGVEYSW
Mb3570c|M.bovis_AF2122/97 VQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
Rv3540c|M.tuberculosis_H37Rv VQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
MMAR_5027|M.marinum_M VQHAAMAVATGIADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
MUL_4101|M.ulcerans_Agy99 VQHAAMAVATGIADVVVAYRAFNERSDMRFGQVQTRLTENADSTGVDNSF
TH_2985|M.thermoresistible__bu IGLARAAIVAGDASVVVTVMALQQ-AKQRLGSVFSAMEPDP-----INSF
MAV_2614|M.avium_104 IQRACHAILTAEAATILCVFADAPLVAGRG-AGSTYAHSGG--NAGVRGL
Mvan_4311|M.vanbaalenii_PYR-1 VQYASMAVQSGMASTIAIVWADAPLKEKSR-SSAAYSGGGRSLPRGFDGI
: * *: :. * .: * : .
MAB_0618|M.abscessus_ATCC_1997 SYPHGLSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPKAFF
MSMEG_5990|M.smegmatis_MC2_155 SYPHGLSTPAASVAMIARRYMHEYGATSADFGVVSVADRKHAANNPKAHF
Mflv_1513|M.gilvum_PYR-GCK SYPHGLSTPAASVAMIAQRYMHEFGATSADFGVISVADRKHAANNPKAHF
Mb3570c|M.bovis_AF2122/97 SYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYF
Rv3540c|M.tuberculosis_H37Rv SYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYF
MMAR_5027|M.marinum_M SYPHGLSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYF
MUL_4101|M.ulcerans_Agy99 SYPHGLSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYF
TH_2985|M.thermoresistible__bu LQPSGLFGPGQLMSVLARRHMHLYGTRREAFAEIAISTRTNAMNRPKAIH
MAV_2614|M.avium_104 ERASGLLGSVPTYALLTQRWLHVTGTRTDALRSVATTARAWACGNPDAVN
Mvan_4311|M.vanbaalenii_PYR-1 TASNGIMSPTTMYALAARRHMQKYGTTSDQLGHIAVAQRAWAQLNPIAQF
. *: . :: ::* :: *: : :: : * * .* *
MAB_0618|M.abscessus_ATCC_1997 YGKPITIEDHQNSRMIADPVRLLDCCQESDGGVAIVVTTPERAKDLKNRP
MSMEG_5990|M.smegmatis_MC2_155 YGKPITIEDHQNSRWIAEPLRLLDCCQETDGGVAIVVTTPERAKDLKHRP
Mflv_1513|M.gilvum_PYR-GCK YGKPITIEDHQNSRWIAEPLRLLDCCQETDGGVAIVVTTPERARDLKHRP
Mb3570c|M.bovis_AF2122/97 YGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRP
Rv3540c|M.tuberculosis_H37Rv YGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRP
MMAR_5027|M.marinum_M YQKPITIDDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAERARDLQQRP
MUL_4101|M.ulcerans_Agy99 YQKPITIDDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAERARDLQQRP
TH_2985|M.thermoresistible__bu R-NPLTLEDYFNARMIAEPLCLYDFCQETDGAVAVITTSMDRARDLRQPP
MAV_2614|M.avium_104 R-EPLDDAGYDSSPMVAEPLRLLDCARPVNGAVAVVLTGRPSVGGTR---
Mvan_4311|M.vanbaalenii_PYR-1 CGTPLTLQEYHDSRYIAEPFHLYDCCLVSNGGVAVIVTSLERARALRQPP
*: : .: :*:*. * * . :*.**:: * . :
MAB_0618|M.abscessus_ATCC_1997 VIIEAAAQGSGEDQFTMYSYYRDELG-LPEMG--LVGRQLWDQSGLTPND
MSMEG_5990|M.smegmatis_MC2_155 VTIEAAAQGSGADQFTMYSYYRDELG-LPEMG--LVGRQLWQQSGLTPDD
Mflv_1513|M.gilvum_PYR-GCK AIIEAAAQGAGADQFTMYSYYREELG-LPEMG--LVGRQLWAQSGLTPQD
Mb3570c|M.bovis_AF2122/97 VVIEAAAQGCSPDQYTMVSYYRPELDGLPEMG--LVGRQLWAQSGLTPAD
Rv3540c|M.tuberculosis_H37Rv VVIEAAAQGCSPDQYTMVSYYRPELDGLPEMG--LVGRQLWAQSGLTPAD
MMAR_5027|M.marinum_M AIIEAASQGSSPDQYTMVSYYRPELDGLPEMG--LVGQQLWQQSGLKPTD
MUL_4101|M.ulcerans_Agy99 AIIEAASQGSSPDQYTMVSYYRPELDGLPEMG--LVGQQLWQQSGLKPTD
TH_2985|M.thermoresistible__bu VPVVAAAHGGVKDWGRAFAWMGMPDEYFASSGNKPIAERLYRQAGITAKD
MAV_2614|M.avium_104 LRVRGTGRDHPVRR-RRSGAESWFGGGGRAVQ------DALEQAGMARSD
Mvan_4311|M.vanbaalenii_PYR-1 VRVLGWAQAHPGRAGIRNDDFGLVSGAAQSGP------DALKMANTSLDE
: . .: :. :
MAB_0618|M.abscessus_ATCC_1997 IQTAILYDHFTPYTLLQLEELGFCGKGEAK-DFIANGAIELGGKLPINTH
MSMEG_5990|M.smegmatis_MC2_155 IQTAILYDHFTPYTLLQLEELGFCGKGEAK-DFIAGGAIEIGGKLPINTH
Mflv_1513|M.gilvum_PYR-GCK IQTAVLYDHFTPYTLIQLEELGFCGKGEAK-DFIAGGAIEIGGRLPINTH
Mb3570c|M.bovis_AF2122/97 VQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIEVGGRLPINTH
Rv3540c|M.tuberculosis_H37Rv VQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIEVGGRLPINTH
MMAR_5027|M.marinum_M IQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIELGGRLPINTH
MUL_4101|M.ulcerans_Agy99 IQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIELGGRLPINTH
TH_2985|M.thermoresistible__bu IDVALLYDHFTPMVLMQLEDYGFCAKGEGG-AFAAGGAIGPGGRLPINTA
MAV_2614|M.avium_104 LHVAELYDPFSIVTLVLLDEYRLTGDIPAG-AFVRDGHTGPGGTLPTNTG
Mvan_4311|M.vanbaalenii_PYR-1 VGVAQIYDCYTFTALLTLEDYGFVPKGEGGPAMAEPGMIGPGGRIKFNTG
: .* :** :: .*: *:: : . . : * ** : **
MAB_0618|M.abscessus_ATCC_1997 GGQLGEAYIHGMNGIAEGVRQLRGTS-VNQVPNVEHVLVT--AGTGVPTS
MSMEG_5990|M.smegmatis_MC2_155 GGQLGEAYIHGMNGIAEGVRQLRGTS-VNQVEGVEHVLVT--AGTGVPTS
Mflv_1513|M.gilvum_PYR-GCK GGQLGEAYIHGMNGIAEGVRQLRGTS-VNQVPDVEHVLVT--AGTGVPTS
Mb3570c|M.bovis_AF2122/97 GGQLGEAYIHGMNGIAEGVRQLRGTS-VNPVAGVEHVLVT--AGTGVPTS
Rv3540c|M.tuberculosis_H37Rv GGQLGEAYIHGMNGIAEGVRQLRGTS-VNPVAGVEHVLVT--AGTGVPTS
MMAR_5027|M.marinum_M GGQLGEAYIHGMNGIAEGVRQLRGTS-VNPVPDVEHVLVT--AGTGVPTS
MUL_4101|M.ulcerans_Agy99 GGQLGEAYIHGMNGIAEGVRQLRGTS-VNPVPDVEHVLVT--AGTGVPTS
TH_2985|M.thermoresistible__bu GGNLSEGYIHGMNHVVEGVRQMRGTS-PNQVEGAEVCLVT--SGIPVSTS
MAV_2614|M.avium_104 GGQLSGFYLQGMTPLAEAMIQLRGTGGQRQVPGATVALVGGIGGRMDHHA
Mvan_4311|M.vanbaalenii_PYR-1 GGELSSFYMWGMTPLHEAVVQARGQGGERQVDDHDRVLVSGNGGILDYHS
**:*. *: **. : *.: * ** . . * . ** .* :
MAB_0618|M.abscessus_ATCC_1997 GLILG---
MSMEG_5990|M.smegmatis_MC2_155 GLILG---
Mflv_1513|M.gilvum_PYR-GCK GLILG---
Mb3570c|M.bovis_AF2122/97 GLILG---
Rv3540c|M.tuberculosis_H37Rv GLILG---
MMAR_5027|M.marinum_M GLILG---
MUL_4101|M.ulcerans_Agy99 GLILG---
TH_2985|M.thermoresistible__bu AMILRRP-
MAV_2614|M.avium_104 ALVLERAA
Mvan_4311|M.vanbaalenii_PYR-1 TLVLGTDN
::*