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SDPTPAIAGLGITEQGKVYGRTARQFAAQAVRLAAADAGIEMADIDGLIVSGGIKARIGINLQNALGLVD LKLLTEMQGFGSTAAQMVQYASMAVQSGMASTIAIVWADAPLKEKSRSSAAYSGGGRSLPRGFDGITASN GIMSPTTMYALAARRHMQKYGTTSDQLGHIAVAQRAWAQLNPIAQFCGTPLTLQEYHDSRYIAEPFHLYD CCLVSNGGVAVIVTSLERARALRQPPVRVLGWAQAHPGRAGIRNDDFGLVSGAAQSGPDALKMANTSLDE VGVAQIYDCYTFTALLTLEDYGFVPKGEGGPAMAEPGMIGPGGRIKFNTGGGELSSFYMWGMTPLHEAVV QARGQGGERQVDDHDRVLVSGNGGILDYHSTLVLGTDN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4311 | - | - | 100% (389) | hypothetical protein Mvan_4311 |
| M. vanbaalenii PYR-1 | Mvan_0899 | - | 4e-52 | 36.52% (397) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_5253 | - | 4e-50 | 35.05% (388) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 6e-47 | 34.60% (396) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_1513 | - | 2e-49 | 34.61% (393) | lipid-transfer protein |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 6e-47 | 34.60% (396) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 2e-49 | 35.11% (393) | lipid-transfer protein |
| M. marinum M | MMAR_4250 | ltp2 | 2e-47 | 35.01% (377) | keto acyl-CoA thiolase, Ltp2 |
| M. avium 104 | MAV_1903 | - | 6e-62 | 38.87% (391) | thiolase |
| M. smegmatis MC2 155 | MSMEG_5990 | - | 2e-49 | 34.79% (388) | lipid-transfer protein |
| M. thermoresistible (build 8) | TH_3402 | - | 3e-61 | 38.80% (366) | PUTATIVE putative thiolase |
| M. ulcerans Agy99 | MUL_4101 | ltp2_1 | 7e-47 | 33.59% (396) | lipid-transfer protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0618|M.abscessus_ATCC_1997 -------MTGLSGRSAIAGIGATDFSKKSGRSELRLAAEAVLDALDDAGL
MSMEG_5990|M.smegmatis_MC2_155 -------MTGLSGKAAIAGIGATDFSKNSGRSELRLAAECVLDALDDAGL
Mflv_1513|M.gilvum_PYR-GCK ---------MLSGKAAIAGIGATDFSKNSGRSELRLAAEAVLDALDDAGL
Mb3570c|M.bovis_AF2122/97 ---------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDALADAGL
Rv3540c|M.tuberculosis_H37Rv ---------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDALADAGL
MUL_4101|M.ulcerans_Agy99 ---------MLSGKAAIVGIGATDFSKNSGRSELRLAAEAVRDALDDAGL
MMAR_4250|M.marinum_M ------MTAPLAGAAAIVGIGQTEFSKESGRSELQLACEAVSAALDDAGV
Mvan_4311|M.vanbaalenii_PYR-1 ---------MSDPTPAIAGLGITEQGKVYGRTARQFAAQAVRLAAADAGI
MAV_1903|M.avium_104 ---------MSSPDVDLVGLGMTRMSLRPGATPLELATEASTAALADAGL
TH_3402|M.thermoresistible__bu VSNNIRAGGIRGGTAIVGVADEVSPSGVIDVPLRELEARVITAALADAGL
: . . . . . .: . * ***:
MAB_0618|M.abscessus_ATCC_1997 SPSDVDGLVTFTMD----SNLETAVARATGIGELKFFSQIGYGGGAAAAT
MSMEG_5990|M.smegmatis_MC2_155 EPSDVDGLVTFTMD----SNQETAVARSTGIGELKFFSQIGYGGGAAAAT
Mflv_1513|M.gilvum_PYR-GCK TTADVDGLVTFSMD----SNLETAVARSTGIGELKFFSQIGYGGGAAAAT
Mb3570c|M.bovis_AF2122/97 SPTDVDGLTTFTMD----TNTEIAVARAAGIGELTFFSKIHYGGGAACAT
Rv3540c|M.tuberculosis_H37Rv SPTDVDGLTTFTMD----TNTEIAVARAAGIGELTFFSKIHYGGGAACAT
MUL_4101|M.ulcerans_Agy99 SPADVDGLTTFTMD----TNTEIAVARAAGIGELKFFSKIHYGGGAACAT
MMAR_4250|M.marinum_M TPGEVDGMVTFTMD----ASDEIDVARNVGIGDLNFFSRVPHGGGAAAGT
Mvan_4311|M.vanbaalenii_PYR-1 EMADIDGLIVSG--GIK-ARIGINLQNALGLVDLKLLTEMQGFGSTAAQM
MAV_1903|M.avium_104 GRADVDGLLVGSSQGVRPDRLGVGFAAQGGFSDLRLLEHVEIKGATTIAM
TH_3402|M.thermoresistible__bu SLSDVDGLCTCTG---GTLMHSVELAEYLGIS-PRFTDATQTGGASYGLY
::**: . . *: : *.:
MAB_0618|M.abscessus_ATCC_1997 VQQAALAVAAGVAEVVVAYRAFNERSEFRFGQVMTGLSSTADSRGVEYSW
MSMEG_5990|M.smegmatis_MC2_155 VQQAALAVATGVAEVVVAYRAFNERSEFRFGQVMTGLTTNADSRGVEYSW
Mflv_1513|M.gilvum_PYR-GCK VQQAALAVATGVAEVVVAYRAFNERSEHRFGQVMTGLTVNADSRGVEYSW
Mb3570c|M.bovis_AF2122/97 VQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
Rv3540c|M.tuberculosis_H37Rv VQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
MUL_4101|M.ulcerans_Agy99 VQHAAMAVATGIADVVVAYRAFNERSDMRFGQVQTRLTENADSTGVDNSF
MMAR_4250|M.marinum_M VAHAAMAVATGVAEVVVCYRAFNERSGMRFGGSGRTSTETP----LFMAH
Mvan_4311|M.vanbaalenii_PYR-1 VQYASMAVQSGMASTIAIVWADAPLKEKSRSSAAYSGGGRSLPR-GFDGI
MAV_1903|M.avium_104 IARARHAITTGEAATVLCVFADAPLVAGRGAGSTYAQSGGNV---GVRGL
TH_3402|M.thermoresistible__bu IEHAAAAIAAGLAETVVIVYASTPRAARKRGEKGLGVFATPER----LEW
: * *: :* * .: * .
MAB_0618|M.abscessus_ATCC_1997 SYPHGLSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPKAFF
MSMEG_5990|M.smegmatis_MC2_155 SYPHGLSTPAASVAMIARRYMHEYGATSADFGVVSVADRKHAANNPKAHF
Mflv_1513|M.gilvum_PYR-GCK SYPHGLSTPAASVAMIAQRYMHEFGATSADFGVISVADRKHAANNPKAHF
Mb3570c|M.bovis_AF2122/97 SYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYF
Rv3540c|M.tuberculosis_H37Rv SYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYF
MUL_4101|M.ulcerans_Agy99 SYPHGLSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYF
MMAR_4250|M.marinum_M YAPFGLLTPAAWVALHAQRYMSTYGVTNEDFGRIAVVDRAHAARNPDAWF
Mvan_4311|M.vanbaalenii_PYR-1 TASNGIMSPTTMYALAARRHMQKYGTTSDQLGHIAVAQRAWAQLNPIAQF
MAV_1903|M.avium_104 ERASGLLGSVPTYALLAQRWLHVTGAGTDALRHVATTARTWAQGNPDAVN
TH_3402|M.thermoresistible__bu ETPFGVMLPLSAYALAANRHMAVYGTTAEQLAQIAVDTRTWATRNPRANQ
. *: . . *: *.* : *. : ::. * * ** *
MAB_0618|M.abscessus_ATCC_1997 YGKPITIEDHQNSRMIADP-VRLLDCCQESDGGVAIVVTTPERAKDLKNR
MSMEG_5990|M.smegmatis_MC2_155 YGKPITIEDHQNSRWIAEP-LRLLDCCQETDGGVAIVVTTPERAKDLKHR
Mflv_1513|M.gilvum_PYR-GCK YGKPITIEDHQNSRWIAEP-LRLLDCCQETDGGVAIVVTTPERARDLKHR
Mb3570c|M.bovis_AF2122/97 YGKPITIEDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAARARDLKQR
Rv3540c|M.tuberculosis_H37Rv YGKPITIEDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAARARDLKQR
MUL_4101|M.ulcerans_Agy99 YQKPITIDDHQNSRWIAEP-LRLLDCCQETDGAVAIVVTSAERARDLQQR
MMAR_4250|M.marinum_M YQRPITLADHQNSRWIIEPVLRLLDCCQESDGGVALVVTSTERARDLRQP
Mvan_4311|M.vanbaalenii_PYR-1 CGTPLTLQEYHDSRYIAEP-FHLYDCCLVSNGGVAVIVTSLERARALRQP
MAV_1903|M.avium_104 R-EPLDDAGYDASPMIAEP-LRLLDCARPVNGAVAVVLTGRTSVGTQR--
TH_3402|M.thermoresistible__bu R-DPITVDDVLNSGYVVEP-IHKLECCLVTDGAAAIVVTSAERARHLER-
*: * : :* .: :*. :*..*:::* . .
MAB_0618|M.abscessus_ATCC_1997 PVIIEAAAQGSGEDQFTMYSYYRDELG-LPEMGLVGRQLWDQSGLTPNDI
MSMEG_5990|M.smegmatis_MC2_155 PVTIEAAAQGSGADQFTMYSYYRDELG-LPEMGLVGRQLWQQSGLTPDDI
Mflv_1513|M.gilvum_PYR-GCK PAIIEAAAQGAGADQFTMYSYYREELG-LPEMGLVGRQLWAQSGLTPQDI
Mb3570c|M.bovis_AF2122/97 PVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADV
Rv3540c|M.tuberculosis_H37Rv PVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPADV
MUL_4101|M.ulcerans_Agy99 PAIIEAASQGSSPDQYTMVSYYRPELDGLPEMGLVGQQLWQQSGLKPTDI
MMAR_4250|M.marinum_M AAVITAAAQGAAAEGEMMTSYYREDITGLPEMGVVAKRLWRDSGLKPADI
Mvan_4311|M.vanbaalenii_PYR-1 PVRVLGWAQAHP----GRAGIRNDDFGLVSGAAQSGPDALKMANTSLDEV
MAV_1903|M.avium_104 -LRVRGTGRHHP----VRR-RRAGAESWFGGGGQAVDDALEQAGMTRSDL
TH_3402|M.thermoresistible__bu PVYVLGAASAAS----HAMITQMPDLTVTPG-AVSGPAAFAAAGLRPDDI
: . . . :. ::
MAB_0618|M.abscessus_ATCC_1997 QTAILYDHFTPYTLLQLEELGFCGKGEAK-DFIANGAIELGGKLPINTHG
MSMEG_5990|M.smegmatis_MC2_155 QTAILYDHFTPYTLLQLEELGFCGKGEAK-DFIAGGAIEIGGKLPINTHG
Mflv_1513|M.gilvum_PYR-GCK QTAVLYDHFTPYTLIQLEELGFCGKGEAK-DFIAGGAIEIGGRLPINTHG
Mb3570c|M.bovis_AF2122/97 QTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIEVGGRLPINTHG
Rv3540c|M.tuberculosis_H37Rv QTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIEVGGRLPINTHG
MUL_4101|M.ulcerans_Agy99 QTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIELGGRLPINTHG
MMAR_4250|M.marinum_M QTAFIYDHFTPFVFTQLEELGFCGRGEAK-EFATVENLSLGGLLPINTNG
Mvan_4311|M.vanbaalenii_PYR-1 GVAQIYDCYTFTALLTLEDYGFVPKGEGGPAMAEPGMIGPGGRIKFNTGG
MAV_1903|M.avium_104 DVAELYDPFSIVTLVLLEEYRLTGDVPAG-AFVRDGHTGPGGTLPTNTGG
TH_3402|M.thermoresistible__bu DVVELYDSFTITVLLALEDLGFCKKGEGG-PFVGDGVLAPGGALPGQTTG
.. :** :: .: **: : . : ** : :* *
MAB_0618|M.abscessus_ATCC_1997 GQLGEAY--IHGMNGIAEGVRQLRGTSVNQVPNVEHVLVTAGTG---VPT
MSMEG_5990|M.smegmatis_MC2_155 GQLGEAY--IHGMNGIAEGVRQLRGTSVNQVEGVEHVLVTAGTG---VPT
Mflv_1513|M.gilvum_PYR-GCK GQLGEAY--IHGMNGIAEGVRQLRGTSVNQVPDVEHVLVTAGTG---VPT
Mb3570c|M.bovis_AF2122/97 GQLGEAY--IHGMNGIAEGVRQLRGTSVNPVAGVEHVLVTAGTG---VPT
Rv3540c|M.tuberculosis_H37Rv GQLGEAY--IHGMNGIAEGVRQLRGTSVNPVAGVEHVLVTAGTG---VPT
MUL_4101|M.ulcerans_Agy99 GQLGEAY--IHGMNGIAEGVRQLRGTSVNPVPDVEHVLVTAGTG---VPT
MMAR_4250|M.marinum_M GLLGEAY--IHGMNGITEAVRQVRGTSYNQVDHVEHVLVTSGTG---VPT
Mvan_4311|M.vanbaalenii_PYR-1 GELSSFY--MWGMTPLHEAVVQARGQGGERQVDDHDRVLVSGNGGILDYH
MAV_1903|M.avium_104 GQLSGFY--LQGMTPLAEAVIQLRGTGGERQVPGATVALVGGIGGRLDHH
TH_3402|M.thermoresistible__bu GGLSYTHPGAFGAFLLVEATRQLRGECGDRQVADAQTALAHGTGGVLSAT
* *. : * : *.. * ** : :. * *
MAB_0618|M.abscessus_ATCC_1997 SGLILG-----
MSMEG_5990|M.smegmatis_MC2_155 SGLILG-----
Mflv_1513|M.gilvum_PYR-GCK SGLILG-----
Mb3570c|M.bovis_AF2122/97 SGLILG-----
Rv3540c|M.tuberculosis_H37Rv SGLILG-----
MUL_4101|M.ulcerans_Agy99 SGLILG-----
MMAR_4250|M.marinum_M SGLILAPAG--
Mvan_4311|M.vanbaalenii_PYR-1 STLVLGTDN--
MAV_1903|M.avium_104 AALVLERAA--
TH_3402|M.thermoresistible__bu STVILGTEAVL
: ::*