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SSPDVDLVGLGMTRMSLRPGATPLELATEASTAALADAGLGRADVDGLLVGSSQGVRPDRLGVGFAAQGG FSDLRLLEHVEIKGATTIAMIARARHAITTGEAATVLCVFADAPLVAGRGAGSTYAQSGGNVGVRGLERA SGLLGSVPTYALLAQRWLHVTGAGTDALRHVATTARTWAQGNPDAVNREPLDDAGYDASPMIAEPLRLLD CARPVNGAVAVVLTGRTSVGTQRLRVRGTGRHHPVRRRRAGAESWFGGGGQAVDDALEQAGMTRSDLDVA ELYDPFSIVTLVLLEEYRLTGDVPAGAFVRDGHTGPGGTLPTNTGGGQLSGFYLQGMTPLAEAVIQLRGT GGERQVPGATVALVGGIGGRLDHHAALVLERAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1903 | - | - | 100% (384) | thiolase |
| M. avium 104 | MAV_2614 | - | 0.0 | 89.01% (382) | thiolase |
| M. avium 104 | MAV_1918 | - | 7e-41 | 34.34% (396) | thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 3e-36 | 32.05% (365) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_0636 | - | 4e-39 | 34.45% (389) | putative nonspecific lipid-transfer protein |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 3e-36 | 32.05% (365) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 7e-35 | 31.62% (370) | lipid-transfer protein |
| M. marinum M | MMAR_5027 | ltp2_1 | 5e-36 | 31.56% (358) | acetyl-CoA acetyltransferase (PaaJ-like), Ltp2_1 |
| M. smegmatis MC2 155 | MSMEG_5990 | - | 8e-34 | 31.89% (370) | lipid-transfer protein |
| M. thermoresistible (build 8) | TH_2985 | - | 6e-44 | 35.37% (376) | PUTATIVE putative nonspecific lipid-transfer protein |
| M. ulcerans Agy99 | MUL_4101 | ltp2_1 | 1e-35 | 31.37% (357) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_4311 | - | 7e-62 | 38.87% (391) | hypothetical protein Mvan_4311 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5027|M.marinum_M --MLSGK--AAIVGIGATDFSKNSG---RSELRLAAEAVRDALDDAGLSP
MUL_4101|M.ulcerans_Agy99 --MLSGK--AAIVGIGATDFSKNSG---RSELRLAAEAVRDALDDAGLSP
Mb3570c|M.bovis_AF2122/97 --MLSGQ--AAIVGIGATDFSKNSG---RSELRLAAEAVLDALADAGLSP
Rv3540c|M.tuberculosis_H37Rv --MLSGQ--AAIVGIGATDFSKNSG---RSELRLAAEAVLDALADAGLSP
MAB_0618|M.abscessus_ATCC_1997 MTGLSGR--SAIAGIGATDFSKKSG---RSELRLAAEAVLDALDDAGLSP
MSMEG_5990|M.smegmatis_MC2_155 MTGLSGK--AAIAGIGATDFSKNSG---RSELRLAAECVLDALDDAGLEP
TH_2985|M.thermoresistible__bu VTHSNGLRDVAIVGIGATPYYKRGGSVPKTTTELACEAIIAACEDAGLSV
Mflv_0636|M.gilvum_PYR-GCK --MSSLRDKACIVGVGHTAYRRDGTES-ATDLGLQLEAAHAAIVDAGLSA
MAV_1903|M.avium_104 --MSSPD--VDLVGLGMTRMSLRPG---ATPLELATEASTAALADAGLGR
Mvan_4311|M.vanbaalenii_PYR-1 --MSDPT--PAIAGLGITEQGKVYG---RTARQFAAQAVRLAAADAGIEM
. :.*:* * : : :. * ***:
MMAR_5027|M.marinum_M ADVDGLTTFTMDTN------TEIAVARAAGIGELKFFSKIHYGGGAACAT
MUL_4101|M.ulcerans_Agy99 ADVDGLTTFTMDTN------TEIAVARAAGIGELKFFSKIHYGGGAACAT
Mb3570c|M.bovis_AF2122/97 TDVDGLTTFTMDTN------TEIAVARAAGIGELTFFSKIHYGGGAACAT
Rv3540c|M.tuberculosis_H37Rv TDVDGLTTFTMDTN------TEIAVARAAGIGELTFFSKIHYGGGAACAT
MAB_0618|M.abscessus_ATCC_1997 SDVDGLVTFTMDSN------LETAVARATGIGELKFFSQIGYGGGAAAAT
MSMEG_5990|M.smegmatis_MC2_155 SDVDGLVTFTMDSN------QETAVARSTGIGELKFFSQIGYGGGAAAAT
TH_2985|M.thermoresistible__bu HDIDGFAYYSGASAGYTEKMDTADFMETLGIPEVRFTAALTSGGGGSAGA
Mflv_0636|M.gilvum_PYR-GCK GEIDGLICPINGGT-------AEDFIANLGLTHVRYAVTSHTGGAASVAG
MAV_1903|M.avium_104 ADVDGLLVGSSQGVRP--DRLGVGFAAQGGFSDLRLLEHVEIKGATTIAM
Mvan_4311|M.vanbaalenii_PYR-1 ADIDGLIVSG--GIK---ARIGINLQNALGLVDLKLLTEMQGFGSTAAQM
::**: . *: .: *. :
MMAR_5027|M.marinum_M VQHAAMAVATGIADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
MUL_4101|M.ulcerans_Agy99 VQHAAMAVATGIADVVVAYRAFNERSDMRFGQVQTRLTENADSTGVDNSF
Mb3570c|M.bovis_AF2122/97 VQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
Rv3540c|M.tuberculosis_H37Rv VQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENADSTGVDNSF
MAB_0618|M.abscessus_ATCC_1997 VQQAALAVAAGVAEVVVAYRAFNERSEFRFGQVMTGLSSTADSRGVEYSW
MSMEG_5990|M.smegmatis_MC2_155 VQQAALAVATGVAEVVVAYRAFNERSEFRFGQVMTGLTTNADSRGVEYSW
TH_2985|M.thermoresistible__bu IGLARAAIVAGDASVVVTVMALQQ-AKQRLGSVFSAMEPDP-----INSF
Mflv_0636|M.gilvum_PYR-GCK LATAAMAVWSGVARHVLIPAGWCGYSGPRARGMAS--SADMAIGKVVRDY
MAV_1903|M.avium_104 IARARHAITTGEAATVLCVFADAPLVAGRG-AGSTYAQSGGNV--GVRGL
Mvan_4311|M.vanbaalenii_PYR-1 VQYASMAVQSGMASTIAIVWADAPLKEKSR-SSAAYSGGGRSLPRGFDGI
: * *: :* * : . : .
MMAR_5027|M.marinum_M SYPHGLSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYF
MUL_4101|M.ulcerans_Agy99 SYPHGLSTPAAQVAMIAKRYMHLSGASSRDFGAVSVADRKHAAKNPKAYF
Mb3570c|M.bovis_AF2122/97 SYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYF
Rv3540c|M.tuberculosis_H37Rv SYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPKAYF
MAB_0618|M.abscessus_ATCC_1997 SYPHGLSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPKAFF
MSMEG_5990|M.smegmatis_MC2_155 SYPHGLSTPAASVAMIARRYMHEYGATSADFGVVSVADRKHAANNPKAHF
TH_2985|M.thermoresistible__bu LQPSGLFGPGQLMSVLARRHMHLYGTRREAFAEIAISTRTNAMNRPKAIH
Mflv_0636|M.gilvum_PYR-GCK YAPQGAVSAVHQYALVADRYVRKYDVPPEAMGAVAVAFRANAQLNSNAVM
MAV_1903|M.avium_104 ERASGLLGSVPTYALLAQRWLHVTGAGTDALRHVATTARTWAQGNPDAVN
Mvan_4311|M.vanbaalenii_PYR-1 TASNGIMSPTTMYALAARRHMQKYGTTSDQLGHIAVAQRAWAQLNPIAQF
. * . :: * * :: .. : :: : * * .. *
MMAR_5027|M.marinum_M YQKPITIDDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAERARDLQQRP
MUL_4101|M.ulcerans_Agy99 YQKPITIDDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAERARDLQQRP
Mb3570c|M.bovis_AF2122/97 YGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRP
Rv3540c|M.tuberculosis_H37Rv YGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLKQRP
MAB_0618|M.abscessus_ATCC_1997 YGKPITIEDHQNSRMIADPVRLLDCCQESDGGVAIVVTTPERAKDLKNRP
MSMEG_5990|M.smegmatis_MC2_155 YGKPITIEDHQNSRWIAEPLRLLDCCQETDGGVAIVVTTPERAKDLKHRP
TH_2985|M.thermoresistible__bu R-NPLTLEDYFNARMIAEPLCLYDFCQETDGAVAVITTSMDRARDLRQPP
Mflv_0636|M.gilvum_PYR-GCK CGRELTMQDYLDAPPISTPFRLFDCSLETDGAAAVVVSAADRAADSPHRP
MAV_1903|M.avium_104 R-EPLDDAGYDASPMIAEPLRLLDCARPVNGAVAVVLTGRTSVGTQR---
Mvan_4311|M.vanbaalenii_PYR-1 CGTPLTLQEYHDSRYIAEPFHLYDCCLVSNGGVAVIVTSLERARALRQPP
: : : *: *. * * . :*..*:: : .
MMAR_5027|M.marinum_M AIIEAASQGSSPDQYTMVSYYRPELDGLPEMG--LVGQQLWQQSGLKPTD
MUL_4101|M.ulcerans_Agy99 AIIEAASQGSSPDQYTMVSYYRPELDGLPEMG--LVGQQLWQQSGLKPTD
Mb3570c|M.bovis_AF2122/97 VVIEAAAQGCSPDQYTMVSYYRPELDGLPEMG--LVGRQLWAQSGLTPAD
Rv3540c|M.tuberculosis_H37Rv VVIEAAAQGCSPDQYTMVSYYRPELDGLPEMG--LVGRQLWAQSGLTPAD
MAB_0618|M.abscessus_ATCC_1997 VIIEAAAQGSGEDQFTMYSYYRDELG-LPEMG--LVGRQLWDQSGLTPND
MSMEG_5990|M.smegmatis_MC2_155 VTIEAAAQGSGADQFTMYSYYRDELG-LPEMG--LVGRQLWQQSGLTPDD
TH_2985|M.thermoresistible__bu VPVVAAAHGGVKDWGRAFAWMGMPDEYFASSGNKPIAERLYRQAGITAKD
Mflv_0636|M.gilvum_PYR-GCK VFVMSVAEGRPFPVDEFANRADPLEIGLAEAAP-----RAFADAGVTPSD
MAV_1903|M.avium_104 LRVRGTGRHHPVRR-RRAGAESWFGGGGQAVD------DALEQAGMTRSD
Mvan_4311|M.vanbaalenii_PYR-1 VRVLGWAQAHPGRAGIRNDDFGLVSGAAQSGP------DALKMANTSLDE
: . .. :. . :
MMAR_5027|M.marinum_M IQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIELGGRLPINTH
MUL_4101|M.ulcerans_Agy99 IQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIELGGRLPINTH
Mb3570c|M.bovis_AF2122/97 VQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIEVGGRLPINTH
Rv3540c|M.tuberculosis_H37Rv VQTAVLYDHFTPFTLIQLEELGFCGKGEAK-DFIADGAIEVGGRLPINTH
MAB_0618|M.abscessus_ATCC_1997 IQTAILYDHFTPYTLLQLEELGFCGKGEAK-DFIANGAIELGGKLPINTH
MSMEG_5990|M.smegmatis_MC2_155 IQTAILYDHFTPYTLLQLEELGFCGKGEAK-DFIAGGAIEIGGKLPINTH
TH_2985|M.thermoresistible__bu IDVALLYDHFTPMVLMQLEDYGFCAKGEGG-AFAAGGAIGPGGRLPINTA
Mflv_0636|M.gilvum_PYR-GCK IDLLEVYDSFTVNVLRQIEAAGFCKPGEAA-DFVLDGCIAADGSLPTNLN
MAV_1903|M.avium_104 LDVAELYDPFSIVTLVLLEEYRLTGDVPAG-AFVRDGHTGPGGTLPTNTG
Mvan_4311|M.vanbaalenii_PYR-1 VGVAQIYDCYTFTALLTLEDYGFVPKGEGGPAMAEPGMIGPGGRIKFNTG
: :** :: .* :* : . : * .* : *
MMAR_5027|M.marinum_M GGQLGEAYIHGMNGIAEGVRQLRG-TSVNPVPDVEHVLVT-AGTGVPTSG
MUL_4101|M.ulcerans_Agy99 GGQLGEAYIHGMNGIAEGVRQLRG-TSVNPVPDVEHVLVT-AGTGVPTSG
Mb3570c|M.bovis_AF2122/97 GGQLGEAYIHGMNGIAEGVRQLRG-TSVNPVAGVEHVLVT-AGTGVPTSG
Rv3540c|M.tuberculosis_H37Rv GGQLGEAYIHGMNGIAEGVRQLRG-TSVNPVAGVEHVLVT-AGTGVPTSG
MAB_0618|M.abscessus_ATCC_1997 GGQLGEAYIHGMNGIAEGVRQLRG-TSVNQVPNVEHVLVT-AGTGVPTSG
MSMEG_5990|M.smegmatis_MC2_155 GGQLGEAYIHGMNGIAEGVRQLRG-TSVNQVEGVEHVLVT-AGTGVPTSG
TH_2985|M.thermoresistible__bu GGNLSEGYIHGMNHVVEGVRQMRG-TSPNQVEGAEVCLVT-SGIPVSTSA
Mflv_0636|M.gilvum_PYR-GCK GGLLSEAHVQGMNNLVEAVRQLRGGLPQRQVHNAELAVVTGMGGGWGSGA
MAV_1903|M.avium_104 GGQLSGFYLQGMTPLAEAVIQLRGTGGERQVPGATVALVGGIGGRLDHHA
Mvan_4311|M.vanbaalenii_PYR-1 GGELSSFYMWGMTPLHEAVVQARGQGGERQVDDHDRVLVSGNGGILDYHS
** *. :: **. : *.* * ** . * . :* * .
MMAR_5027|M.marinum_M LILG----
MUL_4101|M.ulcerans_Agy99 LILG----
Mb3570c|M.bovis_AF2122/97 LILG----
Rv3540c|M.tuberculosis_H37Rv LILG----
MAB_0618|M.abscessus_ATCC_1997 LILG----
MSMEG_5990|M.smegmatis_MC2_155 LILG----
TH_2985|M.thermoresistible__bu MILRRP--
Mflv_0636|M.gilvum_PYR-GCK LAILRR--
MAV_1903|M.avium_104 ALVLERAA
Mvan_4311|M.vanbaalenii_PYR-1 TLVLGTDN
: