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KVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDLVAYRDESGELHILEAHCKHLGAHLGHGGTVVGDCV QCPFHGWRWGPDGTNRYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQPHGKEPQWEMPDIFGKFPQFET DPAAYYRAYPEFSRRAEREPVHPQIVAENAPDSAHFEYVHHATVTPRVLDWKIVEQEWQFVAGWPDANSD DPEALALRFHSHLFGLGGAISVFEGAQNHRLIFTCTPVDDECSDLFYSIWWPRLPGDTADVPEGKLREVI EKQFLSTVFDDLQIWRYQKYVEHPPLSKVDAKGYMALRKWATQFYELPPAGTSSPA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_1603 | - | - | 100% (337) | Rieske (2Fe-2S) domain-containing protein |
M. avium 104 | MAV_2544 | - | 4e-65 | 39.88% (336) | iron-sulfur cluster-binding protein, Rieske family protein |
M. avium 104 | MAV_3666 | - | 5e-64 | 37.61% (327) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3556 | - | 4e-27 | 26.91% (327) | oxidoreductase |
M. gilvum PYR-GCK | Mflv_4333 | - | 1e-163 | 72.59% (332) | Rieske (2Fe-2S) domain-containing protein |
M. tuberculosis H37Rv | Rv3526 | - | 4e-27 | 26.91% (327) | oxidoreductase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0726 | - | 6e-68 | 39.70% (335) | hypothetical protein MAB_0726 |
M. marinum M | MMAR_1935 | - | 6e-65 | 38.53% (327) | oxidoreductase |
M. smegmatis MC2 155 | MSMEG_2244 | - | 1e-164 | 72.32% (336) | Rieske (2Fe-2S) domain-containing protein |
M. thermoresistible (build 8) | TH_4222 | - | 1e-171 | 77.41% (332) | PUTATIVE Rieske [2Fe-2S] domain protein |
M. ulcerans Agy99 | MUL_2161 | - | 5e-65 | 38.46% (338) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_2012 | - | 1e-162 | 72.40% (337) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MAV_1603|M.avium_104 --------------MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDL TH_4222|M.thermoresistible__bu --------------VKVPFTWKVTGWFMIGWAPEFPVGEVRPLRYFGEDL Mflv_4333|M.gilvum_PYR-GCK --------------MKVPFTWKVTGWFMIGWSAEFEVGDVKALRYFGEDL Mvan_2012|M.vanbaalenii_PYR-1 --------------MKVPFTWKVTGWFMIGWSAEYEVGEVKALKYFGEDL MSMEG_2244|M.smegmatis_MC2_155 --------------MKVPFTWRVTGWFMIGWSAEYPVGEVKALKYFGEDL MMAR_1935|M.marinum_M -------------MAKPPLSMKPTGWFQVAWSDEIGVGDVRTMKYFDQEL MUL_2161|M.ulcerans_Agy99 -------------MAKPPLSTKPTGWFQVAWSDEIGVGDVRTMKYFDQEL MAB_0726|M.abscessus_ATCC_1997 -------------MPKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREM Mb3556|M.bovis_AF2122/97 MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKL Rv3526|M.tuberculosis_H37Rv MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKL : **. :. : : * : : *. .: MAV_1603|M.avium_104 VAYRDESGELHILEAHCKHLGAHLGHGGTVVGDCVQCPFHGWRWGPDGTN TH_4222|M.thermoresistible__bu VAYRDESGALHVMEAHCKHLGAHIGHGGTVIGDCVECPFHGWRWGPDGRN Mflv_4333|M.gilvum_PYR-GCK AAYRDESGRLHVLEAHCKHLGAHIGHGGKVVDDCIECPFHGWRWGPDGSN Mvan_2012|M.vanbaalenii_PYR-1 AAYRDESGQLHVLEAHCKHLGAHIGHGGTVVGDCIECPFHGWRWGPEGDN MSMEG_2244|M.smegmatis_MC2_155 AAYRDESGHLHVLEAHCKHLGAHIGHGGKVVGECIECPFHGWRWGPEGTN MMAR_1935|M.marinum_M IAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWNQLGRN MUL_2161|M.ulcerans_Agy99 IAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWNQLGRN MAB_0726|M.abscessus_ATCC_1997 VAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPFHGWEWNRDGRN Mb3556|M.bovis_AF2122/97 VVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRC Rv3526|M.tuberculosis_H37Rv VVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRC .: . * * :::.:*.*:*..:. * * .: : ****.*.*. * MAV_1603|M.avium_104 RYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQPHGKEPQWEMPDIFGKF TH_4222|M.thermoresistible__bu THIPYQPDRPNKALTLRVYPVLEQYDCVFIWHHPHGKEPQWEMPDIFRSF Mflv_4333|M.gilvum_PYR-GCK TYIPYQPDRPNRGLRLRSYPVEEQYGCIFMWYQPQGKEPQWELPDIFHKF Mvan_2012|M.vanbaalenii_PYR-1 TYIPYRPDRPNRGLRLRSYPVREQYGCIFMWYQPQGKEPQWELPDIFHKF MSMEG_2244|M.smegmatis_MC2_155 TYIPYQPDKPNRGLRLRSYPVQEQYGCIFMWYQPHGKEPQWELPDIFHKF MMAR_1935|M.marinum_M VCIPYQ-DRPNRGRRIRTYPVVERNASVYLWHDVEGRAPFFDAPDVFAGF MUL_2161|M.ulcerans_Agy99 VCIPYQ-DRPNRGRRIRTYPVVERNASVYLWHDVEGRAPFFDAPDVFAGF MAB_0726|M.abscessus_ATCC_1997 VCIPYE-RRPNPLRRIRSYPVVERNEAVYIWHDTAGRPPYFDVPDVFTGF Mb3556|M.bovis_AF2122/97 KLVPYARRTPR-MARTRSWTTDVRSGLLFVWHDHEGNPP-----DPAVRI Rv3526|M.tuberculosis_H37Rv KLVPYARRTPR-MARTRSWTTDVRSGLLFVWHDHEGNPP-----DPAVRI :** *. : :.. : :::*:. *. * * : MAV_1603|M.avium_104 PQFETDPAAYYRAYPEFSRRAEREPVHPQIVAENAPDSAHFEYVHHATVT TH_4222|M.thermoresistible__bu PQFDTDPQRYYRPYPEFSRFAGNEPVHPQIVAENGPDSAHFRYVHRATVT Mflv_4333|M.gilvum_PYR-GCK PQFETDANAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHGATVT Mvan_2012|M.vanbaalenii_PYR-1 PQFETDANAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHKATVT MSMEG_2244|M.smegmatis_MC2_155 PQFNTDPNAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHGATVT MMAR_1935|M.marinum_M NDGSS-VADYYP---QQRLYRHTLELHPQYVLENGVDFAHFKYVHNTPIV MUL_2161|M.ulcerans_Agy99 NDGSS-VADYYP---QQRLYRHTLELHPQYVLENGVDFAHFKYVHNTPIV MAB_0726|M.abscessus_ATCC_1997 GDGGS-ARDYYPGYPHSTLYRERLQLHPQYVLENGVDFAHFKYVHKTPFI Mb3556|M.bovis_AF2122/97 PEIPEAASDEWTDWRWNRILIEGS--NCRDIIDNVTDMAHFFYIHFG-LP Rv3526|M.tuberculosis_H37Rv PEIPEAASDEWTDWRWNRILIEGS--NCRDIIDNVTDMAHFFYIHFG-LP : : : : : :* * :** *:* . MAV_1603|M.avium_104 PRVLDWKIVE--QEWQFVAGWPDANSDDPEALALRFHSHLFGLGGAISVF TH_4222|M.thermoresistible__bu PRMLEWKIVD--QQWQFLTGWPAESSDDPDKMALRIHSHMFGLGGAISAF Mflv_4333|M.gilvum_PYR-GCK PVCLHWEHVD--EEWRFLTGWPDARSDDPDKMALRIHSHFSGLGFAMSAF Mvan_2012|M.vanbaalenii_PYR-1 PVCLHWEHVD--EEWRFLTGWPDARSDDPDRMALKIHSHFSGLGFAMSAF MSMEG_2244|M.smegmatis_MC2_155 PVCLHWEHVD--EEWRFLTGWPDARSDDPNKMALRIHSHFSGLGFAMSAF MMAR_1935|M.marinum_M PVFTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAVTKS MUL_2161|M.ulcerans_Agy99 PVFTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAVTKS MAB_0726|M.abscessus_ATCC_1997 PRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKS Mb3556|M.bovis_AF2122/97 TYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMIN Rv3526|M.tuberculosis_H37Rv TYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMIN . . . . . ..: :* :. MAV_1603|M.avium_104 EGA-------QNHRLIFTCTPVDDECSDLFYSIWWPRLPGDTADVPEGKL TH_4222|M.thermoresistible__bu EGA-------SNHRLIFAVTPVDDEYSNMFYSIWWPRNPGDPSDVPPDDV Mflv_4333|M.gilvum_PYR-GCK EGS-------SNHRLIFACTPVDDEVSDMFYSIWWPKLPGETSDIPPAEV Mvan_2012|M.vanbaalenii_PYR-1 EGS-------SNHRLIFACTPVDDEVSDMFYSIWWPKLPGETSDVPPPEV MSMEG_2244|M.smegmatis_MC2_155 EGS-------SNHRLIFACTPVDDEVSDMFYSIWWPKEPGGASDIPPEHV MMAR_1935|M.marinum_M WGM-------VDNRTISAITPVDESTSDVRFMVYIGRTPGKDPARAE-HK MUL_2161|M.ulcerans_Agy99 WGM-------VDNRTISAITPVDESTSDVRFMVYIGRTPGKDPARAE-LK MAB_0726|M.abscessus_ATCC_1997 WGM-------VDNRTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPP-QS Mb3556|M.bovis_AF2122/97 WLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEK-PKGMSEEMTDKL Rv3526|M.tuberculosis_H37Rv WLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEK-PKGMSEEMTDKL : : ** :. : : : : * . MAV_1603|M.avium_104 REVIEKQFLSTVFDDLQIWRYQKYVEHPPLSKVDAKGYMALRKWATQFYE TH_4222|M.thermoresistible__bu RARVEKQYLVTVWDDLEIWRYQKYVENPALSRVDAKPYMALRKWAQQFYE Mflv_4333|M.gilvum_PYR-GCK IEKVERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKPYMAMRKWAQRFYE Mvan_2012|M.vanbaalenii_PYR-1 IEKVERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKPYMAMRKWAQQFYE MSMEG_2244|M.smegmatis_MC2_155 RAKVEKQFLKTVWEDCDIWRYQKYVEHPALAKIDAKPYMAMRKWATQFYE MMAR_1935|M.marinum_M AAEFGREVIRQFEQDIQIWAHQRYCDPPALTTDELAGFTAIRRWAKQFYP MUL_2161|M.ulcerans_Agy99 AAEFGREVIRQFEPDIQIWAHQRYCDPPTLTTDELAGFTAIRRWAKQFYP MAB_0726|M.abscessus_ATCC_1997 AKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEGFIALRKWATQFYP Mb3556|M.bovis_AF2122/97 SRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVY-QLRRWYEQFYV Rv3526|M.tuberculosis_H37Rv SRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVY-QLRRWYEQFYV . . . * .** :: : * * : : :*:* :** MAV_1603|M.avium_104 LPP-AGTSSPA------------------------------------- TH_4222|M.thermoresistible__bu VAP-TGAPAGLP------------------------------------ Mflv_4333|M.gilvum_PYR-GCK VPP-VGDPVASR------------------------------------ Mvan_2012|M.vanbaalenii_PYR-1 VPAKVPAPATTA------------------------------------ MSMEG_2244|M.smegmatis_MC2_155 VPP-VETALPRG------------------------------------ MMAR_1935|M.marinum_M DGIGGSAAEVYAALQKG------------------------------- MUL_2161|M.ulcerans_Agy99 DGISGSAAEVYAALQKG------------------------------- MAB_0726|M.abscessus_ATCC_1997 E---ESTA---------------------------------------- Mb3556|M.bovis_AF2122/97 DVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH Rv3526|M.tuberculosis_H37Rv DVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH