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KVPFTWKVTGWFMIGWSAEYEVGEVKALKYFGEDLAAYRDESGQLHVLEAHCKHLGAHIGHGGTVVGDCI ECPFHGWRWGPEGDNTYIPYRPDRPNRGLRLRSYPVREQYGCIFMWYQPQGKEPQWELPDIFHKFPQFET DANAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHKATVTPVCLHWEHVDEEWRFLTGWPDARSD DPDRMALKIHSHFSGLGFAMSAFEGSSNHRLIFACTPVDDEVSDMFYSIWWPKLPGETSDVPPPEVIEKV ERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKPYMAMRKWAQQFYEVPAKVPAPATTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2012 | - | - | 100% (339) | Rieske (2Fe-2S) domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3784 | - | 2e-65 | 37.46% (331) | Rieske (2Fe-2S) domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5211 | - | 1e-27 | 26.71% (337) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 3e-27 | 28.01% (332) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4333 | - | 0.0 | 95.14% (329) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv3526 | - | 3e-27 | 28.01% (332) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0726 | - | 3e-66 | 37.46% (331) | hypothetical protein MAB_0726 |
| M. marinum M | MMAR_1935 | - | 2e-65 | 37.50% (328) | oxidoreductase |
| M. avium 104 | MAV_1603 | - | 1e-162 | 72.40% (337) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2244 | - | 0.0 | 91.49% (329) | Rieske (2Fe-2S) domain-containing protein |
| M. thermoresistible (build 8) | TH_4222 | - | 1e-163 | 74.03% (335) | PUTATIVE Rieske [2Fe-2S] domain protein |
| M. ulcerans Agy99 | MUL_2161 | - | 2e-65 | 38.07% (331) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2012|M.vanbaalenii_PYR-1 --------------MKVPFTWKVTGWFMIGWSAEYEVGEVKALKYFGEDL
Mflv_4333|M.gilvum_PYR-GCK --------------MKVPFTWKVTGWFMIGWSAEFEVGDVKALRYFGEDL
MSMEG_2244|M.smegmatis_MC2_155 --------------MKVPFTWRVTGWFMIGWSAEYPVGEVKALKYFGEDL
MAV_1603|M.avium_104 --------------MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDL
TH_4222|M.thermoresistible__bu --------------VKVPFTWKVTGWFMIGWAPEFPVGEVRPLRYFGEDL
MMAR_1935|M.marinum_M -------------MAKPPLSMKPTGWFQVAWSDEIGVGDVRTMKYFDQEL
MUL_2161|M.ulcerans_Agy99 -------------MAKPPLSTKPTGWFQVAWSDEIGVGDVRTMKYFDQEL
MAB_0726|M.abscessus_ATCC_1997 -------------MPKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREM
Mb3556|M.bovis_AF2122/97 MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKL
Rv3526|M.tuberculosis_H37Rv MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKL
: **. :. : : * : : *. .:
Mvan_2012|M.vanbaalenii_PYR-1 AAYRDESGQLHVLEAHCKHLGAHIGHGGTVVGDCIECPFHGWRWGPEGDN
Mflv_4333|M.gilvum_PYR-GCK AAYRDESGRLHVLEAHCKHLGAHIGHGGKVVDDCIECPFHGWRWGPDGSN
MSMEG_2244|M.smegmatis_MC2_155 AAYRDESGHLHVLEAHCKHLGAHIGHGGKVVGECIECPFHGWRWGPEGTN
MAV_1603|M.avium_104 VAYRDESGELHILEAHCKHLGAHLGHGGTVVGDCVQCPFHGWRWGPDGTN
TH_4222|M.thermoresistible__bu VAYRDESGALHVMEAHCKHLGAHIGHGGTVIGDCVECPFHGWRWGPDGRN
MMAR_1935|M.marinum_M IAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWNQLGRN
MUL_2161|M.ulcerans_Agy99 IAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWNQLGRN
MAB_0726|M.abscessus_ATCC_1997 VAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPFHGWEWNRDGRN
Mb3556|M.bovis_AF2122/97 VVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRC
Rv3526|M.tuberculosis_H37Rv VVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRC
.: . * * :::.:*.*:*..:. * * .: : ****.*.*. *
Mvan_2012|M.vanbaalenii_PYR-1 TYIPYRPDRPNRGLRLRSYPVREQYGCIFMWYQPQGKEPQWELPDIFHKF
Mflv_4333|M.gilvum_PYR-GCK TYIPYQPDRPNRGLRLRSYPVEEQYGCIFMWYQPQGKEPQWELPDIFHKF
MSMEG_2244|M.smegmatis_MC2_155 TYIPYQPDKPNRGLRLRSYPVQEQYGCIFMWYQPHGKEPQWELPDIFHKF
MAV_1603|M.avium_104 RYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQPHGKEPQWEMPDIFGKF
TH_4222|M.thermoresistible__bu THIPYQPDRPNKALTLRVYPVLEQYDCVFIWHHPHGKEPQWEMPDIFRSF
MMAR_1935|M.marinum_M VCIPYQ-DRPNRGRRIRTYPVVERNASVYLWHDVEGRAPFFDAPDVFAGF
MUL_2161|M.ulcerans_Agy99 VCIPYQ-DRPNRGRRIRTYPVVERNASVYLWHDVEGRAPFFDAPDVFAGF
MAB_0726|M.abscessus_ATCC_1997 VCIPYE-RRPNPLRRIRSYPVVERNEAVYIWHDTAGRPPYFDVPDVFTGF
Mb3556|M.bovis_AF2122/97 KLVPYARRTPR-MARTRSWTTDVRSGLLFVWHDHEGNPP-----DPAVRI
Rv3526|M.tuberculosis_H37Rv KLVPYARRTPR-MARTRSWTTDVRSGLLFVWHDHEGNPP-----DPAVRI
:** *. : :.. : :::*:. *. * * :
Mvan_2012|M.vanbaalenii_PYR-1 PQFETDANAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHKATVT
Mflv_4333|M.gilvum_PYR-GCK PQFETDANAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHGATVT
MSMEG_2244|M.smegmatis_MC2_155 PQFNTDPNAYYRPYPEFSSRADAIPVHPQIVAENGPDSSHFRYVHGATVT
MAV_1603|M.avium_104 PQFETDPAAYYRAYPEFSRRAEREPVHPQIVAENAPDSAHFEYVHHATVT
TH_4222|M.thermoresistible__bu PQFDTDPQRYYRPYPEFSRFAGNEPVHPQIVAENGPDSAHFRYVHRATVT
MMAR_1935|M.marinum_M NDGSS-VADYYP---QQRLYRHTLELHPQYVLENGVDFAHFKYVHNTPIV
MUL_2161|M.ulcerans_Agy99 NDGSS-VADYYP---QQRLYRHTLELHPQYVLENGVDFAHFKYVHNTPIV
MAB_0726|M.abscessus_ATCC_1997 GDGGS-ARDYYPGYPHSTLYRERLQLHPQYVLENGVDFAHFKYVHKTPFI
Mb3556|M.bovis_AF2122/97 PEIPEAASDEWTDWRWNRILIEGS--NCRDIIDNVTDMAHFFYIHFG-LP
Rv3526|M.tuberculosis_H37Rv PEIPEAASDEWTDWRWNRILIEGS--NCRDIIDNVTDMAHFFYIHFG-LP
: : : : : :* * :** *:* .
Mvan_2012|M.vanbaalenii_PYR-1 PVCLHWEHVD--EEWRFLTGWPDARSDDPDRMALKIHSHFSGLGFAMSAF
Mflv_4333|M.gilvum_PYR-GCK PVCLHWEHVD--EEWRFLTGWPDARSDDPDKMALRIHSHFSGLGFAMSAF
MSMEG_2244|M.smegmatis_MC2_155 PVCLHWEHVD--EEWRFLTGWPDARSDDPNKMALRIHSHFSGLGFAMSAF
MAV_1603|M.avium_104 PRVLDWKIVE--QEWQFVAGWPDANSDDPEALALRFHSHLFGLGGAISVF
TH_4222|M.thermoresistible__bu PRMLEWKIVD--QQWQFLTGWPAESSDDPDKMALRIHSHMFGLGGAISAF
MMAR_1935|M.marinum_M PVFTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAVTKS
MUL_2161|M.ulcerans_Agy99 PVFTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAVTKS
MAB_0726|M.abscessus_ATCC_1997 PRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKS
Mb3556|M.bovis_AF2122/97 TYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMIN
Rv3526|M.tuberculosis_H37Rv TYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMIN
. . . . . ..: :* :.
Mvan_2012|M.vanbaalenii_PYR-1 EGS-------SNHRLIFACTPVDDEVSDMFYSIWWPKLPGETSDVPPPEV
Mflv_4333|M.gilvum_PYR-GCK EGS-------SNHRLIFACTPVDDEVSDMFYSIWWPKLPGETSDIPPAEV
MSMEG_2244|M.smegmatis_MC2_155 EGS-------SNHRLIFACTPVDDEVSDMFYSIWWPKEPGGASDIPPEHV
MAV_1603|M.avium_104 EGA-------QNHRLIFTCTPVDDECSDLFYSIWWPRLPGDTADVPEGKL
TH_4222|M.thermoresistible__bu EGA-------SNHRLIFAVTPVDDEYSNMFYSIWWPRNPGDPSDVPPDDV
MMAR_1935|M.marinum_M WGM-------VDNRTISAITPVDESTSDVRFMVYIGRTPGKDPARAE-HK
MUL_2161|M.ulcerans_Agy99 WGM-------VDNRTISAITPVDESTSDVRFMVYIGRTPGKDPARAE-LK
MAB_0726|M.abscessus_ATCC_1997 WGM-------VDNRTVSAVTPVDDETCDVRFTVFIGRQPGDDSAEPP-QS
Mb3556|M.bovis_AF2122/97 WLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEK-PKGMSEEMTDKL
Rv3526|M.tuberculosis_H37Rv WLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEK-PKGMSEEMTDKL
: : ** :. : : : : * .
Mvan_2012|M.vanbaalenii_PYR-1 IEKVERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKPYMAMRKWAQQFYE
Mflv_4333|M.gilvum_PYR-GCK IEKVERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKPYMAMRKWAQRFYE
MSMEG_2244|M.smegmatis_MC2_155 RAKVEKQFLKTVWEDCDIWRYQKYVEHPALAKIDAKPYMAMRKWATQFYE
MAV_1603|M.avium_104 REVIEKQFLSTVFDDLQIWRYQKYVEHPPLSKVDAKGYMALRKWATQFYE
TH_4222|M.thermoresistible__bu RARVEKQYLVTVWDDLEIWRYQKYVENPALSRVDAKPYMALRKWAQQFYE
MMAR_1935|M.marinum_M AAEFGREVIRQFEQDIQIWAHQRYCDPPALTTDELAGFTAIRRWAKQFYP
MUL_2161|M.ulcerans_Agy99 AAEFGREVIRQFEPDIQIWAHQRYCDPPTLTTDELAGFTAIRRWAKQFYP
MAB_0726|M.abscessus_ATCC_1997 AKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEGFIALRKWATQFYP
Mb3556|M.bovis_AF2122/97 SRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVY-QLRRWYEQFYV
Rv3526|M.tuberculosis_H37Rv SRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVY-QLRRWYEQFYV
. . . * .** :: : * * : : :*:* :**
Mvan_2012|M.vanbaalenii_PYR-1 VPAKVPAPATTA------------------------------------
Mflv_4333|M.gilvum_PYR-GCK VPP-VGDPVASR------------------------------------
MSMEG_2244|M.smegmatis_MC2_155 VPP-VETALPRG------------------------------------
MAV_1603|M.avium_104 LPP-AGTSSPA-------------------------------------
TH_4222|M.thermoresistible__bu VAP-TGAPAGLP------------------------------------
MMAR_1935|M.marinum_M DGIGGSAAEVYAALQKG-------------------------------
MUL_2161|M.ulcerans_Agy99 DGISGSAAEVYAALQKG-------------------------------
MAB_0726|M.abscessus_ATCC_1997 E---ESTA----------------------------------------
Mb3556|M.bovis_AF2122/97 DVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv DVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH