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MAKPPLSMKPTGWFQVAWSDEIGVGDVRTMKYFDQELIAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGE VLQCPFHGWQWNQLGRNVCIPYQDRPNRGRRIRTYPVVERNASVYLWHDVEGRAPFFDAPDVFAGFNDGS SVADYYPQQRLYRHTLELHPQYVLENGVDFAHFKYVHNTPIVPVFTRHDFDGPVSFVDFTITFEGDDGQQ IEDINSGVEAINGGLGVAVTKSWGMVDNRTISAITPVDESTSDVRFMVYIGRTPGKDPARAEHKAAEFGR EVIRQFEQDIQIWAHQRYCDPPALTTDELAGFTAIRRWAKQFYPDGIGGSAAEVYAALQKG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1935 | - | - | 100% (341) | oxidoreductase |
| M. marinum M | MMAR_3971 | - | 2e-47 | 33.14% (341) | oxidoreductase |
| M. marinum M | MMAR_5015 | - | 8e-27 | 25.85% (325) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 8e-26 | 25.54% (325) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2753 | - | 1e-167 | 78.99% (338) | Rieske (2Fe-2S) region |
| M. tuberculosis H37Rv | Rv3526 | - | 8e-26 | 25.54% (325) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0726 | - | 1e-134 | 65.85% (328) | hypothetical protein MAB_0726 |
| M. avium 104 | MAV_3666 | - | 1e-173 | 85.23% (325) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0734 | - | 1e-170 | 81.14% (334) | Rieske (2Fe-2S) domain-containing protein |
| M. thermoresistible (build 8) | TH_2615 | - | 1e-171 | 79.18% (341) | PUTATIVE Rieske [2Fe-2S] domain protein |
| M. ulcerans Agy99 | MUL_2161 | - | 0.0 | 98.53% (341) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3784 | - | 1e-175 | 82.84% (338) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1935|M.marinum_M -------------MAKPPLSMKPTGWFQVAWSDEIGVGDVRTMKYFDQEL
MUL_2161|M.ulcerans_Agy99 -------------MAKPPLSTKPTGWFQVAWSDEIGVGDVRTMKYFDQEL
MAV_3666|M.avium_104 -------------MAKPPLSMKPTGWFQVAWSDEIGVGDVHKMKYFDQEM
MSMEG_0734|M.smegmatis_MC2_155 -------MGGTATMAKPPLSMKPTGWFQVAWSDEVGVGDVRAMKYFGQEM
TH_2615|M.thermoresistible__bu -------------MAKPPLSMKPTGWFQVAWSDEVGIGEVRAMKYFGEEM
Mflv_2753|M.gilvum_PYR-GCK -------------MAPPPLSMKPTGWFQVAWSDEIAIGDVHTMKYFGQEM
Mvan_3784|M.vanbaalenii_PYR-1 -------------MAKPPLSMKPTGWFQVAWSDEIGIGDVHTMKYFDQEM
MAB_0726|M.abscessus_ATCC_1997 -------------MPKPPLSMRPTGWFQVAWSAQITVGAVHRMSYFGREM
Mb3556|M.bovis_AF2122/97 MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKL
Rv3526|M.tuberculosis_H37Rv MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKL
. . : . **. :. : : * : :. *. ::
MMAR_1935|M.marinum_M IAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWNQLGRN
MUL_2161|M.ulcerans_Agy99 IAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWNQLGRN
MAV_3666|M.avium_104 VAWRAESGQLTVMNAYCEHLGAHLGYGGKVVGEVLQCPFHGWQWSAEGRN
MSMEG_0734|M.smegmatis_MC2_155 VAWRSESGQVTVMNAYCEHLGAHLGFGGTVVGEVIQCPFHGWQWNAEGRN
TH_2615|M.thermoresistible__bu VAWRSESGRVTVMNAYCEHLGAHLGFGGEVLGEVIQCPFHGWQWNAEGRN
Mflv_2753|M.gilvum_PYR-GCK VAWRAGSGQLTVMNAYCEHLGAHLGFGGSVQGEVLQCPFHGWQWNQQGRN
Mvan_3784|M.vanbaalenii_PYR-1 VAWRAESGQLTVMNAYCEHLGAHLGFGGTVHGEVLQCPFHGWQWNQQGRN
MAB_0726|M.abscessus_ATCC_1997 VAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPFHGWEWNRDGRN
Mb3556|M.bovis_AF2122/97 VVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRC
Rv3526|M.tuberculosis_H37Rv VVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRC
:.: * : *::.:*.*:*..*. * * *: : ****.*.*. **
MMAR_1935|M.marinum_M VCIPYQDRPNRGRRIRTYPVVERNASVYLWHDVEGR--APFFDAPDVFAG
MUL_2161|M.ulcerans_Agy99 VCIPYQDRPNRGRRIRTYPVVERNASVYLWHDVEGR--APFFDAPDVFAG
MAV_3666|M.avium_104 VCIPYQDRPNRGRRMRTYPVVERNASVYIWHDLQRR--EPYFDPPDVFAA
MSMEG_0734|M.smegmatis_MC2_155 VCIPYQDRPNRGRRMPTYPVAERNEAIYIWHDVLGR--EPFFDAPDVFAS
TH_2615|M.thermoresistible__bu VCIPYQDRPNRGRRMKTYPVVERNESIYIWHDLLGR--EPFFDPPDVFAS
Mflv_2753|M.gilvum_PYR-GCK VCIPYEDRPNRGRRIKTYPVIERNESVYIWHDIENR--EPFFDAPDVFAS
Mvan_3784|M.vanbaalenii_PYR-1 VCIPYEDRPNRGRRIKTYPVAERNASIYIWHDIENR--EPFFDAPDVFAS
MAB_0726|M.abscessus_ATCC_1997 VCIPYERRPNPLRRIRSYPVVERNEAVYIWHDTAGR--PPYFDVPDVFTG
Mb3556|M.bovis_AF2122/97 KLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEA
Rv3526|M.tuberculosis_H37Rv KLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEA
:** *. * ::.. *. :::*** . * . *:: .
MMAR_1935|M.marinum_M FNDGSSVADYYP---QQRLYRHTLELHPQYVLENGVDFAHFKYVHN---T
MUL_2161|M.ulcerans_Agy99 FNDGSSVADYYP---QQRLYRHTLELHPQYVLENGVDFAHFKYVHN---T
MAV_3666|M.avium_104 FGDGSSADDYYP---QQRLYRQALEMHPQYVLENGVDFAHFKFVHN---T
MSMEG_0734|M.smegmatis_MC2_155 FADGSSADGYYP---QQRLYRQALELHPQYVLENGVDFAHFKYVHQ---T
TH_2615|M.thermoresistible__bu FGDGKTATDYHP---QQRLYRQALELHPQYVLENGVDFAHFKFVHR---T
Mflv_2753|M.gilvum_PYR-GCK FGTDATADDYYP---QQRLFEQGHEMHPQYVLENGVDFAHFKYVHG---T
Mvan_3784|M.vanbaalenii_PYR-1 FGDGSSADDYYP---PQRLFEQSLEMHPQYVLENGVDFAHFKYVHG---T
MAB_0726|M.abscessus_ATCC_1997 FGDGGSARDYYPGYPHSTLYRERLQLHPQYVLENGVDFAHFKYVHK---T
Mb3556|M.bovis_AF2122/97 ASDEWTDWRWNR------ILIEGSNCR--DIIDNVTDMAHFFYIHFGLPT
Rv3526|M.tuberculosis_H37Rv ASDEWTDWRWNR------ILIEGSNCR--DIIDNVTDMAHFFYIHFGLPT
: : : . : : :::* .*:*** ::* *
MMAR_1935|M.marinum_M PIVPVFTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAV
MUL_2161|M.ulcerans_Agy99 PIVPVFTRHDFDGPVSFVDFTITFEGDDGQQIEDINSGVEAINGGLGVAV
MAV_3666|M.avium_104 PIVPVFTRHDFAEPVSYVDFTITFEGDDGQKIEDVNSGVQAINGGLGIAV
MSMEG_0734|M.smegmatis_MC2_155 PIVPVFTRHDFAEPWSYVDFTITFEGDENQTIDDVNSGVQAINGGLGIAV
TH_2615|M.thermoresistible__bu PIVPVFTRHDFTEPVSYVDFTITFEGDENQTIDDVDSGVEAINGGLGIAV
Mflv_2753|M.gilvum_PYR-GCK PINPIFTRHDFDDAISYVDFTITFEGDDGQSIDDVRSGVEAINGGLGIAV
Mvan_3784|M.vanbaalenii_PYR-1 PINPIFTRHDFDEPISYVDFTITFEGDDGQRIEEVNSGVEAINGGLGIAV
MAB_0726|M.abscessus_ATCC_1997 PFIPRFTRQEFGTPISYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAV
Mb3556|M.bovis_AF2122/97 YFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMINW
Rv3526|M.tuberculosis_H37Rv YFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAHLDSEASYFGPSFMINW
: * : *. . . : . .: * .. :. .: :
MMAR_1935|M.marinum_M TKS-WG--MVDNRTISAITPVDESTSDVRFMVYIGRTPG--KDPARAEHK
MUL_2161|M.ulcerans_Agy99 TKS-WG--MVDNRTISAITPVDESTSDVRFMVYIGRTPG--KDPARAELK
MAV_3666|M.avium_104 TKS-WG--MIDNRTISAITPVDERTSDVRFMVYIGRTPA--KDAARAQRK
MSMEG_0734|M.smegmatis_MC2_155 TKS-WG--MIDNRTISAVTPVDESTCDVRFMVYIGRTPG--RDDERSATK
TH_2615|M.thermoresistible__bu TKS-WG--MVDNRTISAVTPVDESTCDVRFMVYIGRVPG--RDDERAAAK
Mflv_2753|M.gilvum_PYR-GCK TKS-WG--MIDNRTISAITPVDDSTSDVRFMVYIGRPKGEVRNPERARVK
Mvan_3784|M.vanbaalenii_PYR-1 TKS-WG--MIDNRTISAITPVDESTSDVRFMVYIGRPKGQVRDPERARTK
MAB_0726|M.abscessus_ATCC_1997 TKS-WG--MVDNRTVSAVTPVDDETCDVRFTVFIGRQPG--DDSAEPPQS
Mb3556|M.bovis_AF2122/97 LHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKG--MSEEMTDKL
Rv3526|M.tuberculosis_H37Rv LHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKG--MSEEMTDKL
:. :* :. :.. ** : : ::: * : : . . .
MMAR_1935|M.marinum_M AAEFGREVIRQFEQDIQIWAHQRYCDPPALTTDELAGFTAIRRWAKQFYP
MUL_2161|M.ulcerans_Agy99 AAEFGREVIRQFEPDIQIWAHQRYCDPPTLTTDELAGFTAIRRWAKQFYP
MAV_3666|M.avium_104 AAEFGGEVIRQFTQDIEIWQHQRYSDPPALAADEYQGFMAIRQWAKQFYP
MSMEG_0734|M.smegmatis_MC2_155 AAEFGEEVIRQFTQDIHIWSHQRYSDPPALATAEYEGFTAIRKWAMQFYP
TH_2615|M.thermoresistible__bu AAEFGREVIRQFTQDIHIWSHQRYSDPPALATAEYEGFTAIRNWALQFYP
Mflv_2753|M.gilvum_PYR-GCK AEEFGAEVIRQFRQDIHIWAHQRYSDPPALASSELKGFTAIREWAKKFYP
Mvan_3784|M.vanbaalenii_PYR-1 AEEFGAEVIRQFRQDIHIWAHQRYSDPPALASSELAGFTAIREWAKKFYP
MAB_0726|M.abscessus_ATCC_1997 AKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEGFIALRKWATQFYP
Mb3556|M.bovis_AF2122/97 SRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEED-GAVYQLRRWYEQFYV
Rv3526|M.tuberculosis_H37Rv SRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEED-GAVYQLRRWYEQFYV
: * : * *:.** *: * * *. : .. :*.* :**
MMAR_1935|M.marinum_M DGIGG---------SAAEVYAALQKG----------------------
MUL_2161|M.ulcerans_Agy99 DGISG---------SAAEVYAALQKG----------------------
MAV_3666|M.avium_104 E------------------FAAQEA-----------------------
MSMEG_0734|M.smegmatis_MC2_155 DGRGGSAADLNRRGSAADLASIDQKGTTT-------------------
TH_2615|M.thermoresistible__bu DGKGG---------SAAELASVDQKGTHV-------------------
Mflv_2753|M.gilvum_PYR-GCK DGLGG---------SAAELAARTAN-----------------------
Mvan_3784|M.vanbaalenii_PYR-1 DGKGG---------SAAELAARSAH-----------------------
MAB_0726|M.abscessus_ATCC_1997 EESTA-------------------------------------------
Mb3556|M.bovis_AF2122/97 DVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv DVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH
: