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M. avium 104 MAV_1336 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 1290007 - 1291128
length: 373

DFSFTEEQETIGKLARDLFERRATPERLTELEAGDTRHDAALWEELAAADLLGAALPEAVGGSCASGGGF
VELGVLLAEVGYGVAPVPAYATLVLGADSIARHGSSEQQQRVLPGVIAGSRILTAGLAEPGRSDPARPAT
TARRDGPNWRLDGAKELVPAAQLADTMLIPAALDGGDVGLFLLAADAAGVEIRPVPTTNREPHADVFLDG
ARVSEADRIAGMGLVESLLTRALVALCAIQLGVVERALRIAAEYTTGREQFGRPIGSFQAVQQRMADAFI
DVEAIRWTTWQAAWLVAHGRPADRAARIAKFWAAEAGARVAATAQHVHGGIGIDVTYPLHRYFLWAKHNE
LTLGPASAQLAHLGATYSEGHA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_1336 - - 100% (373) acyl-CoA dehydrogenase domain-containing protein
M. avium 104 MAV_0651 - 5e-68 40.54% (370) putative acyl-CoA dehydrogenase
M. avium 104 MAV_1765 - 7e-44 33.51% (367) pimeloyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3535 fadE27 2e-70 41.80% (378) acyl-CoA dehydrogenase FADE27
M. gilvum PYR-GCK Mflv_1550 - 5e-74 43.90% (369) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3505 fadE27 5e-70 41.53% (378) acyl-CoA dehydrogenase FADE27
M. leprae Br4923 MLBr_00737 fadE25 1e-22 28.88% (374) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4159 - 1e-75 43.01% (365) acyl-CoA dehydrogenase
M. marinum M MMAR_4993 fadE27 2e-69 41.62% (370) acyl-CoA dehydrogenase FadE27
M. smegmatis MC2 155 MSMEG_5907 - 2e-71 43.56% (365) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3944 - 1e-139 69.17% (373) PUTATIVE acyl-CoA dehydrogenase, C- domain protein
M. ulcerans Agy99 MUL_4068 fadE27 7e-68 41.08% (370) acyl-CoA dehydrogenase FadE27
M. vanbaalenii PYR-1 Mvan_5207 - 1e-64 39.73% (370) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1336|M.avium_104                ----------MDFSFTEEQETIGKLARDLFERRATPERLTELEAG----D
TH_3944|M.thermoresistible__bu      ----------MDFSFSEDQETIGKIARQLFEHRATPEHLLDLESG----D
Mb3535|M.bovis_AF2122/97            ----------MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKL----E
Rv3505|M.tuberculosis_H37Rv         ----------MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKL----E
MMAR_4993|M.marinum_M               ----------MDFSTTEAAQDLGGLVDTIVDAVCTPEHQRQLDRL----E
MUL_4068|M.ulcerans_Agy99           ----------MDFSTTEAAQDLGGLVATIVDAVCTPEHQRQLDGL----E
Mflv_1550|M.gilvum_PYR-GCK          ----------MDFTTTEASEDLGGLVRTITESVCTPEHQRELDGLGPDAG
Mvan_5207|M.vanbaalenii_PYR-1       ----------MDFKTTEASEDLGGLVRTITESVCTPEHQRELDGLRPEAG
MSMEG_5907|M.smegmatis_MC2_155      ----------MDFTTTEAAADLGGLVRTITESVCTPEHQRELDGLP----
MAB_4159|M.abscessus_ATCC_1997      ----------MDFSLTEAQTDLAGLTRTIASTISTPERQKELDKQ----D
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP-HAADVDQR-----
                                                *. .*    :      : .   :* :  :::       

MAV_1336|M.avium_104                TRHDAALWEELAAADLLGAALPEAVGGSCASGGGFVELGVLLAEVGYGVA
TH_3944|M.thermoresistible__bu      IRHDPALWQELASADLLGVALPESVGG---TGGGFLELGVLLAEVGRCVA
Mb3535|M.bovis_AF2122/97            QRFDRELWRKLIDAGILSSAAPESLGG---DGFGVLEQVAVLVALGHQLA
Rv3505|M.tuberculosis_H37Rv         QRFDRELWRKLIDAGILSSAAPESLGG---DGFGVLEQVAVLVALGHQLA
MMAR_4993|M.marinum_M               QRFDRELWRKLIDSDILSSAAATQVGG---DGFGVLEQVAILVALGHQLA
MUL_4068|M.ulcerans_Agy99           QRFDRELWRKLIDSDILSSAAATQVGG---DGFGVLEQVAILVALGHQLA
Mflv_1550|M.gilvum_PYR-GCK          GRFDKTLWSKLIDADVLSTTAPESLGG---GGFGVLEEVAVLVALGRQLA
Mvan_5207|M.vanbaalenii_PYR-1       GRFDRDLWGKLIDADILSTTSPESLGG---GGFGVLEEVAVLVALGRQLA
MSMEG_5907|M.smegmatis_MC2_155      ERFDRDLWAKLVEADILSAAAPESVGG---GGFGVLEQTSVLTALGRQLA
MAB_4159|M.abscessus_ATCC_1997      SRFDRQLWTKLAEADILSTAAPESVGG---AGFGVLEQSSILVELGRELA
MLBr_00737|M.leprae_Br4923          ARFPEEALAALNASGFNAIHVPEEYGG---QGADSVAACIVIEEVARVDA
                                     *.       *  :.. .   .   **    * . :    ::  :.   *

MAV_1336|M.avium_104                PVPAYATL-VLGADSIARHGSSEQQQRVLPGVIAGSRILTAGLAE-PGRS
TH_3944|M.thermoresistible__bu      PVPVYATL-LLGADTIARHGDPAVQQHYLPGVVDGSRILSAAIAE-PGSI
Mb3535|M.bovis_AF2122/97            AVPYLESV-VLAAGALARFGSPELQQGWGVSAVSGDRILTVALDG-EMGE
Rv3505|M.tuberculosis_H37Rv         AVPYLESV-VLAAGALARFGSPELQQGWGVSAVSGDRILTVALDG-EMGE
MMAR_4993|M.marinum_M               AVPYLESV-VLAAGALARFGSEELQQSWGAAAVGGEKILAVALDA-EMGE
MUL_4068|M.ulcerans_Agy99           AVPYLESV-VLAAGALARFGSEELQQSWGAAAVGGEKILAVALDA-EMGE
Mflv_1550|M.gilvum_PYR-GCK          AVPYLESV-VLGAGALARFGDDGLQQQWAAPAVTGDKVLTVALDG-EMGE
Mvan_5207|M.vanbaalenii_PYR-1       AVPYLESV-MLAAGALATFGSASLQQDWAAQAIKGEKVLAVAFDG-EMGE
MSMEG_5907|M.smegmatis_MC2_155      AVPYLESV-VAAAGAIAEFGSDAQRAEWGAPAVAGSKILTVALDG-EMGQ
MAB_4159|M.abscessus_ATCC_1997      AVPYLESV-VLAAGALAAFGSEAMRNDWAAPAVAGKKVLTIALEG-EPGE
MLBr_00737|M.leprae_Br4923          SASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGS
                                    ...   ::   .:  :   *.   :            : : .:       

MAV_1336|M.avium_104                DPARPATTARRDGPNWRLDGAKELVPAAQLADTMLIPAALD--GGDVG--
TH_3944|M.thermoresistible__bu      DPLTPSTTARRDGDSWLLDGTKTLVPAAQLAEAIVVTATPQ--DDDGGPA
Mb3535|M.bovis_AF2122/97            GPVQ----AAGTGHGYRLTGTRTQVGYGPVADAFLVPAET-----DSGAA
Rv3505|M.tuberculosis_H37Rv         GPVQ----AAGTGHGYRLTGTRTQVGYGPVADAFLVPAET-----DSGAA
MMAR_4993|M.marinum_M               GPVQ----AARSGAGFRLTGTRTQVGYGPVADAFLVPAET-----DSGTV
MUL_4068|M.ulcerans_Agy99           GPVQ----AARSGAGFRLTGTRTQVGYGPVADAFLVPAET-----DSGTV
Mflv_1550|M.gilvum_PYR-GCK          GPVR----ATTTADGVTLTGTRTQVPFAVGADAFLVPAET-----DSGVA
Mvan_5207|M.vanbaalenii_PYR-1       GPVL----AQGSGDGYTLTGSRTQVAFGVNADAFLVPAET-----DSGTA
MSMEG_5907|M.smegmatis_MC2_155      GPVQ----AQADGDDHRLTGSRTLVSYGPVADAYLVPAET-----GSGVS
MAB_4159|M.abscessus_ATCC_1997      GPVA----ARTEGTGYVLTGNRVLVPFGVEADAYLVPAET-----ETGTA
MLBr_00737|M.leprae_Br4923          DAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGIS
                                    ..      *   . .  * * :  :  .  :    : *         *  

MAV_1336|M.avium_104                LFLLAADAAGVEIRPVPTTN---REPHADVFLDGARVSEADRIAGMGL--
TH_3944|M.thermoresistible__bu      LFVVDTADPGVRTEPVQTTN---GEPFADVELRGARAAHR-LTAGENP--
Mb3535|M.bovis_AF2122/97            VFLVAAGDPGVAVTALATTG---LGSVGHLELNGAKVDAARRVGGTDV--
Rv3505|M.tuberculosis_H37Rv         VFLVAAGDPGVAVTALATTG---LGSVGHLELNGAKVDAARRVGGTDV--
MMAR_4993|M.marinum_M               VFLVAADDPGVSVTALQTTG---LGSVGHLALDGTEVDAARGIGGSDV--
MUL_4068|M.ulcerans_Agy99           VFLVAADDPGVSVTALQTTG---LGSVGHLALDGTEVDAARGIGGSDV--
Mflv_1550|M.gilvum_PYR-GCK          VFLVAAADAGVTVTPLDTTG---HGSVAALDLQGVGITGDRRVGGSEV--
Mvan_5207|M.vanbaalenii_PYR-1       VFLVGSADDGVAVTALDTTG---HGSVAGLQLQGVAIGSDRRVGGPEV--
MSMEG_5907|M.smegmatis_MC2_155      VFIVAADDAGVTETSLNTTG---KGSVAHLDLQDVAVGADRVLGGTQV--
MAB_4159|M.abscessus_ATCC_1997      VFLVSADDAGVTQQALHTTG---KDSSAELILSEVPVPAERKVGGAEV--
MLBr_00737|M.leprae_Br4923          AFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGF
                                     *::     *.   .  ..      .   : :           .      

MAV_1336|M.avium_104                --VESLLTRALVALCAIQLGVVERALRIAAEYTTGREQFGRPIGSFQAVQ
TH_3944|M.thermoresistible__bu      --VESLHTRALIGLCAMQVGVTERALRIAASYTSEREQFGRPIGSFQAVQ
Mb3535|M.bovis_AF2122/97            --VVWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVG
Rv3505|M.tuberculosis_H37Rv         --AVWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVG
MMAR_4993|M.marinum_M               --TAWLRTINTLGRSAFQLGVLERGLRMTAEYARTREQFDRPIGSFQAVG
MUL_4068|M.ulcerans_Agy99           --TAWLRTINTLGRSAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVG
Mflv_1550|M.gilvum_PYR-GCK          --LDWLVTRNALARSAYQLGVVERALELTAQYAREREQFDRPIGSFQAVS
Mvan_5207|M.vanbaalenii_PYR-1       --LDWLVTRHALGRSAYQLGVLERALELTASYAREREQFDRPIGSFQAVS
MSMEG_5907|M.smegmatis_MC2_155      --AEWLTTRVTLGRTAYQLGVLERALELTASYAREREQFDRPIGSFQAVS
MAB_4159|M.abscessus_ATCC_1997      --VEWLRLRESLGHSAYQLGVLERALELTADYARTREQFGKPIGGFQAVA
MLBr_00737|M.leprae_Br4923          KTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQ
                                                   *  :*: : .*  :  *:  *:**...*. **:: 

MAV_1336|M.avium_104                QRMADAFIDVEAIRWTTWQAAWLVAHG--------RPADRAARIAKFWAA
TH_3944|M.thermoresistible__bu      QRMADAFIDTEAIRWTTWHAAWLVSKD--------RSAHREAAMAKFWAA
Mb3535|M.bovis_AF2122/97            QRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAA
Rv3505|M.tuberculosis_H37Rv         QRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAA
MMAR_4993|M.marinum_M               QRLADGYIDVKGLRLTLTQAAWRVSED--------LPAEIDVASAGFWAA
MUL_4068|M.ulcerans_Agy99           QRLADGYIDVKGLRLTLTQAAWRVSED--------LPAEIDVASAGFCAA
Mflv_1550|M.gilvum_PYR-GCK          SRLADGYIDIKGLRLTVTQAAWRVSED--------LPADVDVASAAFWAA
Mvan_5207|M.vanbaalenii_PYR-1       SRLADGYIDIKGLRLTLTQAAWRLSED--------LPADLDVASAAFWAA
MSMEG_5907|M.smegmatis_MC2_155      SRLADGYIDVKGLRLTLTQAAWRLSED--------LPADVDVASAAFWAA
MAB_4159|M.abscessus_ATCC_1997      QRLADGYIDVKGLCLTLWQAAWRVSED--------LPSDVDVATAKFWAA
MLBr_00737|M.leprae_Br4923          FMLADMAMKVEAARLIVYAAAARAERGE-------PDLGFISAASKCFAS
                                      :**  :. :.       **    ..                 :   *:

MAV_1336|M.avium_104                EAGARVAATAQHVHGGIGIDVTYPLHRYFLWAKHNELTLGPASAQLAHLG
TH_3944|M.thermoresistible__bu      EAGARVTATAQQVHGGIGIDITYPLSRYFLWAKQIELTLGSASHQLARLG
Mb3535|M.bovis_AF2122/97            EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIG
Rv3505|M.tuberculosis_H37Rv         EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIG
MMAR_4993|M.marinum_M               EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKEAEFALGGATTALRQIG
MUL_4068|M.ulcerans_Agy99           EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKEAEFALGGATTALRQIG
Mflv_1550|M.gilvum_PYR-GCK          EAGHRVAHTAVHVHGGVGIDIDHPVHRYFLAAKQTEFAVGGATGQLLRIG
Mvan_5207|M.vanbaalenii_PYR-1       EAGHRVAHTTVHVHGGVGIDIDHPVHRYFLAAKQTEFAVGGATGQLLRIG
MSMEG_5907|M.smegmatis_MC2_155      EAGHRVAHTAVHVHGGVGIDMDHPVHRYFLAAKQSEFALGSATGQLLRIG
MAB_4159|M.abscessus_ATCC_1997      DAGHRVAHTAVHVHGGVGIDEDHPVHRYFLAAKRGEFASGSATEQLRRIG
MLBr_00737|M.leprae_Br4923          DIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMS
                                    : . .*:    ::.** *    .*: *::  **  ::  *        :.

MAV_1336|M.avium_104                ATY-----SEGHA
TH_3944|M.thermoresistible__bu      STYRAGGNREGHQ
Mb3535|M.bovis_AF2122/97            REL-----AETPA
Rv3505|M.tuberculosis_H37Rv         REL-----AETPA
MMAR_4993|M.marinum_M               REL-----AETPA
MUL_4068|M.ulcerans_Agy99           REL-----AETPA
Mflv_1550|M.gilvum_PYR-GCK          REL-----ADTPA
Mvan_5207|M.vanbaalenii_PYR-1       REL-----ADTPA
MSMEG_5907|M.smegmatis_MC2_155      REL-----ADTPV
MAB_4159|M.abscessus_ATCC_1997      REL-----ADTPA
MLBr_00737|M.leprae_Br4923          RALLR--------

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_1336	-	-	100% (373)	acyl-CoA dehydrogenase domain-containing protein
M. avium 104	MAV_0651	-	5e-68	40.54% (370)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_1765	-	7e-44	33.51% (367)	pimeloyl-CoA dehydrogenase