For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_1189 (-)

annotation: phospholipase, patatin family protein
coordinates: 1135583 - 1136452
length: 289

VTTKRALVLAGGGIAGIAWETGVLRGIADESPAAARLLTESDVLVGTSAGSAVAAQLCSGHTLDALFDRQ
VAASSPEIDSGVDVEAITELFLTALAEPYDDSEDKTRQQLRRIGAVALATDTVPAPVRRRVIAARLPSHR
WPRRALRLTAIDVDTGELTVFDPASGVDLVDAVAASCAVPGAWPPVAIGGRRYMDGGVASSVNLGVAADC
DVAVVLVPSGVDAPSPFGAGPAAEIAAFPGRALAVFADDRSLAAFGPNPLDPGCRVPSARAGREQGRREA
AAVAEFLGV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1189--100% (289)phospholipase, patatin family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1091-1e-11775.09% (289) hypothetical protein Mb1091
M. gilvum PYR-GCKMflv_2029-1e-10067.48% (286) patatin
M. tuberculosis H37RvRv1062-1e-11775.09% (289) hypothetical protein Rv1062
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4758-4e-0928.15% (238) patatin-like protein
M. marinum MMMAR_4404-1e-11775.43% (289) hypothetical protein MMAR_4404
M. smegmatis MC2 155MSMEG_5285-2e-9965.40% (289) phospholipase, patatin family protein
M. thermoresistible (build 8)TH_1491-4e-8565.62% (256) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1736-2e-1026.09% (253) alpha-beta hydrolase superfamily esterase
M. vanbaalenii PYR-1Mvan_4688-1e-10065.62% (288) patatin

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2029|M.gilvum_PYR-GCK          ----------------MSGT-RALVLAGGGLAGIAWETGVLLGILEEAPE
Mvan_4688|M.vanbaalenii_PYR-1       ----------------MTDVNRALVLAGGGLAGIAWETGVLLGICDESPD
Mb1091|M.bovis_AF2122/97            ----------------MTTR-RALVLAGGGLAGIAWETGVLRGIADESPA
Rv1062|M.tuberculosis_H37Rv         ----------------MTTR-RALVLAGGGLAGIAWETGVLRGIADESPA
MMAR_4404|M.marinum_M               ----------------MAPK-RALVLAGGGLAGIAWETGVLLGIADESPA
MAV_1189|M.avium_104                ----------------MTTK-RALVLAGGGIAGIAWETGVLRGIADESPA
MSMEG_5285|M.smegmatis_MC2_155      ----------------MDSK-RALVLAGGGIAGIAWETGILRGIADESPE
TH_1491|M.thermoresistible__bu      ----------------VANR-RALVLAGGGLAGIAWETGVLLGIADESPH
MAB_4758|M.abscessus_ATCC_1997      -------------------MTTAFVLSGGASLG-SIQVGMLLALAEAG--
MUL_1736|M.ulcerans_Agy99           MAAVRNSSDMAGNRPYDASVTTAFVLSGGASLG-AIQVGMLQALADEG--
                                                          *:**:**.  * : :.*:* .: : .  

Mflv_2029|M.gilvum_PYR-GCK          VGRQLLDSDVLVGTSAGSTVAAQLGSGMGLTELFERQRSESHGAHEIHPG
Mvan_4688|M.vanbaalenii_PYR-1       AGQKLLAADVLLGTSAGSAVAAQVGSGVPLEELFARQLSEEHGAHEIHPG
Mb1091|M.bovis_AF2122/97            AARLLLDSDVLVGTSAGATVAAQISSGCPLDTLYERQLAETS--AEIDPG
Rv1062|M.tuberculosis_H37Rv         AARLLLDSDVLVGTSAGATVAAQISSGCPLDTLYERQLAETS--AEIDPG
MMAR_4404|M.marinum_M               AARLLLDSDVLVGTSAGSAVAAQISSGTSLDALFDRQIAEQS--AELDPG
MAV_1189|M.avium_104                AARLLTESDVLVGTSAGSAVAAQLCSGHTLDALFDRQVAASS--PEIDSG
MSMEG_5285|M.smegmatis_MC2_155      TAQALLGSDVLVGTSAGSTVAAQLSSGLSLDELYERQVGDAS--AELAPT
TH_1491|M.thermoresistible__bu      TADLLLTSDVLVGTSAGSAVAAQLGSGAPLTRLFERQLDPNT--AEIKPR
MAB_4758|M.abscessus_ATCC_1997      -----IAPDLIVGTSVGALNGGWISS--------------------RPDI
MUL_1736|M.ulcerans_Agy99           -----ITPDLIIGTSVGALNGGWIAS--------------------RPDA
                                           .*:::***.*:  .. : *                        

Mflv_2029|M.gilvum_PYR-GCK          VSIDAITDLFLKAMTIPDAT----REQKLQKIGAVAAGTDTVGEAVRRKV
Mvan_4688|M.vanbaalenii_PYR-1       VSIDAITDLFLDAMLTQGAT----KAQKLAKIGCVAAETDTVPEAVRRTV
Mb1091|M.bovis_AF2122/97            VDIDAITDLFLTAVTEPHIS----TRRRLQRIGAVALAVDTVPESVRRQV
Rv1062|M.tuberculosis_H37Rv         VDIDAITDLFLTAVTEPHIS----TRRRLQRIGAVALAVDTVPESVRRQV
MMAR_4404|M.marinum_M               VDIDVITELFLDALREPRIPGVDKIRLRLQRIGSVALATETVSESVRREV
MAV_1189|M.avium_104                VDVEAITELFLTALAEPYDDSEDKTRQQLRRIGAVALATDTVPAPVRRRV
MSMEG_5285|M.smegmatis_MC2_155      AGIGTISELFVDAMLTPGTT----KAQKLRRIGEIAAQTQTVPESVRREV
TH_1491|M.thermoresistible__bu      VAIDDLTAEFLEAVRRPGST-----VEKLRRIGAVALSTGTVGEAERRAV
MAB_4758|M.abscessus_ATCC_1997      DGINGLADLWRSLSRKDVFP----TNLSVGFLGFIGQRQSLVSDSGLRRL
MUL_1736|M.ulcerans_Agy99           AGIRALAGLWRSLTRKEVFP----TQPVTGVMGFLGRRQHLVPNTGLRRI
                                      :  ::  :                     :* :.     *  .  * :

Mflv_2029|M.gilvum_PYR-GCK          IEHRLPSHDWP--ARILRVTAIDIATGELVVLDASSGVTLVDAVAASCAV
Mvan_4688|M.vanbaalenii_PYR-1       IEHRLPAHEWP--QRALRVTAIDIATGELVVFDAASGVGLVDAVAASCAV
Mb1091|M.bovis_AF2122/97            IAQRLPSHDWP--DRVLRVTAIDIATGELVVFHRESNVALVDAVAASCSV
Rv1062|M.tuberculosis_H37Rv         IAQRLPSHDWP--DRVLRVTAIDIATGELVVFHRESNVALVDAVAASCSV
MMAR_4404|M.marinum_M               IAARLPCHDWP--DRALRVTAIDVSTGELVAFDRDSGVELVDAVAASCAV
MAV_1189|M.avium_104                IAARLPSHRWP--RRALRLTAIDVDTGELTVFDPASGVDLVDAVAASCAV
MSMEG_5285|M.smegmatis_MC2_155      IAARLPSHEWPQ-ERILRIAAIDIATGELVGFDRHSGVDLVDAVAASCAV
TH_1491|M.thermoresistible__bu      IAARLPAHDWP--DRDLRLSAVDVGTGELVCFDRDSGVPLVDAVAASCAV
MAB_4758|M.abscessus_ATCC_1997      LKEHLLFRRLEDAPIPLHVVATDVLTGKDVLLS---GGDPIDAIAASAAV
MUL_1736|M.ulcerans_Agy99           LSRELEFTNLEDAPIPLHVVATDVISGTDVLLS---SGNAVDAIAASAAI
                                    :  .*           *:: * *: :*  . :    .   :**:***.::

Mflv_2029|M.gilvum_PYR-GCK          PGVWPPVTIGERRFMDGGVGSTVNMSAAVDCAAAVALVPSPADSPSPWG-
Mvan_4688|M.vanbaalenii_PYR-1       PGVWPPVTIGGRRFMDGGVGSTVNMSAVQDCGAAVVLVPSGANSPSPWG-
Mb1091|M.bovis_AF2122/97            PGAWPPVTIAGRRYMDGGVASSVNLGVADDCDAAVVLVPAGADAPSPFG-
Rv1062|M.tuberculosis_H37Rv         PGAWPPVTIAGRRYMDGGVASSVNLGVADDCDAAVVLVPAGADAPSPFG-
MMAR_4404|M.marinum_M               PGAWPPVTIAGRRYMDGGVASLVNLGVADDCGVAVVLVPTGADAPSPFG-
MAV_1189|M.avium_104                PGAWPPVAIGGRRYMDGGVASSVNLGVAADCDVAVVLVPSGVDAPSPFG-
MSMEG_5285|M.smegmatis_MC2_155      PGAWPPVTIGDRRYIDGGVSSSINLELAVDCQTAVVFIPAGQSAPSPFDP
TH_1491|M.thermoresistible__bu      PGVWPPVTIGERRYMDGGVASTVNMALAADCDTVVALVPSRRDTPSPFG-
MAB_4758|M.abscessus_ATCC_1997      PAVLPPVRIDGRDLMDGGVVNNTPLSHAVALGATEIWVLPTGYACALTET
MUL_1736|M.ulcerans_Agy99           PGIFPPVSINGRELIDGGVVNNTPVSHAVALGADKISVLPTGYSCDLQTL
                                    *.  *** *  *  :**** .   :  .    .    : .   :      

Mflv_2029|M.gilvum_PYR-GCK          AGTAAEIEAFPGEALAVFADDDALAAFGPNPLDPACR--APAAEAGRVQG
Mvan_4688|M.vanbaalenii_PYR-1       TGTVAEIEGFPGATLAVFADDESLAAFGANPLDPACR--APAAQAGRAQG
Mb1091|M.bovis_AF2122/97            GGAAAEIAAATGMVFAVFADDDSLAAFGPNPLDPLCR--VNSAMAGRQQG
Rv1062|M.tuberculosis_H37Rv         GGAAAEIAAATGMVFAVFADDDSLAAFGPNPLDPLCR--VNSAMAGRQQG
MMAR_4404|M.marinum_M               GGSAAEVAEFAGTSLGVFADDDSLAAFGANPLDPRCR--KASALAGRAQG
MAV_1189|M.avium_104                AGPAAEIAAFPGRALAVFADDRSLAAFGPNPLDPGCR--VPSARAGREQG
MSMEG_5285|M.smegmatis_MC2_155      GGIAEEISEFPGAALSIYADDDSLDAFGSNPLDPACR--IPSARAGRAQG
TH_1491|M.thermoresistible__bu      PGPAREIDEFGGAAVGVFADDASVAAFGXXXGGHAVRGPVVEALVGLGFS
MAB_4758|M.abscessus_ATCC_1997      PRGAVPMALHAMTLAINQRLVADVNRFEGSVDLRVVPGLCPVRTSPADFS
MUL_1736|M.ulcerans_Agy99           PASAVTLVLHAMTLAVNHRLAVDIERFEQTVDLRVIRPLCPVSISGADFS
                                       .  :                :  *                      .

Mflv_2029|M.gilvum_PYR-GCK          R------REAARVADFLSGL--------------------
Mvan_4688|M.vanbaalenii_PYR-1       R------REARKVAEFLSV---------------------
Mb1091|M.bovis_AF2122/97            R------REAQAVARLLGV---------------------
Rv1062|M.tuberculosis_H37Rv         R------REAQAVARLLGV---------------------
MMAR_4404|M.marinum_M               R------REASAVAAFLGL---------------------
MAV_1189|M.avium_104                R------REAAAVAEFLGV---------------------
MSMEG_5285|M.smegmatis_MC2_155      R------REAREIAEFLEELAV------------------
TH_1491|M.thermoresistible__bu      A------KQAEEATDKVLADDPDASTSTALRSALSMLGRK
MAB_4758|M.abscessus_ATCC_1997      HADELIGRAHEQTRRWLLMPRFKINQADLLEHHHG-----
MUL_1736|M.ulcerans_Agy99           QSATLIPRPHQATREWLATNPARIGQAALLKPHLH-----
                                           :        :