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AAVRNSSDMAGNRPYDASVTTAFVLSGGASLGAIQVGMLQALADEGITPDLIIGTSVGALNGGWIASRPD AAGIRALAGLWRSLTRKEVFPTQPVTGVMGFLGRRQHLVPNTGLRRILSRELEFTNLEDAPIPLHVVATD VISGTDVLLSSGNAVDAIAASAAIPGIFPPVSINGRELIDGGVVNNTPVSHAVALGADKISVLPTGYSCD LQTLPASAVTLVLHAMTLAVNHRLAVDIERFEQTVDLRVIRPLCPVSISGADFSQSATLIPRPHQATREW LATNPARIGQAALLKPHLH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1736 | - | - | 100% (300) | alpha-beta hydrolase superfamily esterase |
| M. ulcerans Agy99 | MUL_0218 | - | 8e-16 | 31.02% (187) | hypothetical protein MUL_0218 |
| M. ulcerans Agy99 | MUL_3590 | - | 5e-14 | 29.41% (187) | transmembrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1092c | - | 2e-15 | 31.69% (183) | hypothetical protein Mb1092c |
| M. gilvum PYR-GCK | Mflv_2030 | - | 6e-17 | 36.31% (179) | patatin |
| M. tuberculosis H37Rv | Rv1063c | - | 2e-15 | 31.69% (183) | hypothetical protein Rv1063c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4758 | - | 1e-101 | 65.59% (279) | patatin-like protein |
| M. marinum M | MMAR_2150 | - | 1e-155 | 98.58% (281) | alpha-beta hydrolase superfamily esterase |
| M. avium 104 | MAV_1190 | - | 5e-15 | 32.60% (181) | patatin |
| M. smegmatis MC2 155 | MSMEG_5743 | - | 6e-36 | 35.06% (271) | patatin |
| M. thermoresistible (build 8) | TH_4049 | - | 2e-16 | 48.15% (81) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_4687 | - | 5e-16 | 34.07% (182) | patatin |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1092c|M.bovis_AF2122/97 -----MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDI
Rv1063c|M.tuberculosis_H37Rv -----MPAPAALRVRGSSSPRVALALGSGGARGYAHIGVIQALRERGYDI
MAV_1190|M.avium_104 ---------------------MALALGSGGARGYAHIGVIEALQARGYDI
Mflv_2030|M.gilvum_PYR-GCK -------------------MRVALALGSGGARGYAHIGVLNELRERGHEV
Mvan_4687|M.vanbaalenii_PYR-1 -------------------MRVALALGSGGARGYAHIGVLNELTERGHEV
MUL_1736|M.ulcerans_Agy99 MAAVRNSSDMAGNRPYDASVTTAFVLSGGASLGAIQVGMLQALADEGITP
MMAR_2150|M.marinum_M -------------------MTTAFVLSGGASLGAIQVGMLQALADEGITP
MAB_4758|M.abscessus_ATCC_1997 -------------------MTTAFVLSGGASLGSIQVGMLLALAEAGIAP
TH_4049|M.thermoresistible__bu --------------------------------------------------
MSMEG_5743|M.smegmatis_MC2_155 ---------------------MAFVLGGGGVLGAAEAGMALALLESGVRP
Mb1092c|M.bovis_AF2122/97 VGIAGSSMGAVVG----------GVHAAGRLDEFAHWAKSLTQRTILRLL
Rv1063c|M.tuberculosis_H37Rv VGIAGSSMGAVVG----------GVHAAGRLDEFAHWAKSLTQRTILRLL
MAV_1190|M.avium_104 VGVAGSSMGALVG----------GLQAAGRLDEFAEWAKSLTQRTILRLL
Mflv_2030|M.gilvum_PYR-GCK VGIAGSSMGALVG----------GLEAAGKTDEFTLWATSLTQRAVLRLL
Mvan_4687|M.vanbaalenii_PYR-1 VGIAGSSMGALVG----------GLQAAGKLDEYTAWASSLTQRAVLRLL
MUL_1736|M.ulcerans_Agy99 DLIIGTSVGALNGGWIASRPDAAGIRALAGLWRSLTRKEVFPTQPVTGVM
MMAR_2150|M.marinum_M DLIIGTSVGALNGGWIASRPDAAGIRALAGLWRSLTRKEVFPTQPVTGLM
MAB_4758|M.abscessus_ATCC_1997 DLIVGTSVGALNGGWISSRPDIDGINGLADLWRSLSRKDVFPTNLSVGFL
TH_4049|M.thermoresistible__bu --------------------------------------------------
MSMEG_5743|M.smegmatis_MC2_155 DLVCGTSVGAINGAALAADPTPEGARALVKFWDALGGDGVFGGSLIRRAA
Mb1092c|M.bovis_AF2122/97 DPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWF
Rv1063c|M.tuberculosis_H37Rv DPSISAAGILRAEKILDAVRDIVGPVAIEQLPIPYTAVATDLLAGKSVWF
MAV_1190|M.avium_104 DPSISAAGVMRAGKILDAVRDILGPVAIEDLRIPYTAVATDLLAGKSVWF
Mflv_2030|M.gilvum_PYR-GCK DPSISSPGVLRAEKILESVRDILGEVTIEDLPIPYTSVATDLITGKSVWM
Mvan_4687|M.vanbaalenii_PYR-1 DPSITSAGVLRAEKILDAVRAIVGDVTIEELPIPYTAVATDLITGKSVWM
MUL_1736|M.ulcerans_Agy99 GFLGRRQHLVPNTGLRRILSRELEFTNLEDAPIPLHVVATDVISGTDVLL
MMAR_2150|M.marinum_M GFLGRRQHLVPNTGLRRILSRELEFTNLEDAPIPLHVVATDVISGTDVLL
MAB_4758|M.abscessus_ATCC_1997 GFIGQRQSLVSDSGLRRLLKEHLLFRRLEDAPIPLHVVATDVLTGKDVLL
TH_4049|M.thermoresistible__bu --------------------------------------------------
MSMEG_5743|M.smegmatis_MC2_155 EVLRRPTSLHDNSELRRLLRERLPVHTFEELAVPFECVAASIERAREHWF
Mb1092c|M.bovis_AF2122/97 QRGPLDAAIRASIAIPGVIAPHEVDGRLLADGGILDPLPMAPIAGVNADL
Rv1063c|M.tuberculosis_H37Rv QRGPLDAAIRASIAIPGVIAPHEVDGRLLADGGILDPLPMAPIAGVNADL
MAV_1190|M.avium_104 QRGPLDEAIRASIAIPGVIAPHTLDGRLLADGGILDPLPMAPLSAVNADL
Mflv_2030|M.gilvum_PYR-GCK QRGRVDDAIRASIAIPGLITPHVLGGRLLADGGILDPLPMAPIAAAPADI
Mvan_4687|M.vanbaalenii_PYR-1 QRGPLDDAIRASIAIPGVITPYVLDGRLLADGGILDPLPMAPIAAVAADM
MUL_1736|M.ulcerans_Agy99 SSGNAVDAIAASAAIPGIFPPVSINGRELIDGGVVNNTPVSHAVALGADK
MMAR_2150|M.marinum_M SSGNAVDAIAASAAIPGIFPPVSINGRELIDGGVVNNTPVSHAVALGADK
MAB_4758|M.abscessus_ATCC_1997 SGGDPIDAIAASAAVPAVLPPVRIDGRDLMDGGVVNNTPLSHAVALGATE
TH_4049|M.thermoresistible__bu --------------------------------------------------
MSMEG_5743|M.smegmatis_MC2_155 DSGDLVEPVLASCALPGVLPPVRIGDEHFFDGGLVNSIPLDRAVSRGADT
Mb1092c|M.bovis_AF2122/97 TIAVSLNGSE-AGPARDAEP-NVTAEWLNRMVRSTSALFDVSAARSLLDR
Rv1063c|M.tuberculosis_H37Rv TIAVSLNGSE-AGPARDAEP-NVTAEWLNRMVRSTSALFDVSAARSLLDR
MAV_1190|M.avium_104 TIAVNLSGSE-AITRREAEP-AATAEWLTRMMRSTSALFDTAAARSLLDR
Mflv_2030|M.gilvum_PYR-GCK TIAVSLSGEDPAVDRRMQDLRQPTTDWLSRMWRSSSSLLDTKAARSLLET
Mvan_4687|M.vanbaalenii_PYR-1 TIAVSISGDDPEASGRGRESRAPSTDWLNRMWRSSSSLLDTKAARSLLDT
MUL_1736|M.ulcerans_Agy99 ISVLPTGYSC----DLQTLPASAVTLVLHAMTLAVNHRLAVDIER--FEQ
MMAR_2150|M.marinum_M IWVLPTGYSC----DLQTLPASAVTMVLHAMTLAVNHRLAVDIER--FEQ
MAB_4758|M.abscessus_ATCC_1997 IWVLPTGYAC----ALTETPRGAVPMALHAMTLAINQRLVADVNR--FEG
TH_4049|M.thermoresistible__bu ----------------------VLAMALHAFNLAITQRLAVDNTR--FEE
MSMEG_5743|M.smegmatis_MC2_155 IWVLHVGRLE----EELRVPRFLWEVGFAAFEIARRHRFHGDLER--VRS
: : : : * .
Mb1092c|M.bovis_AF2122/97 PTARAVLSRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPG----L
Rv1063c|M.tuberculosis_H37Rv PTARAVLSRFGAAAAESDSWSQAPEIEQRPAGPPADREEAADTPG----L
MAV_1190|M.avium_104 PTARAVLSRLGGPSGDADAWPDNPEEPDQPVLADDD-DEAVELPGAATDV
Mflv_2030|M.gilvum_PYR-GCK PTGRAVLGRFVAADDEP--------IDAPPEVVKHDSADATGVPE----L
Mvan_4687|M.vanbaalenii_PYR-1 PTGRAVLGRFAAGDDEP--------LPEPDDKVTEEPGNAG--------I
MUL_1736|M.ulcerans_Agy99 TVDLRVIRPLCPVSISG--------------------------------A
MMAR_2150|M.marinum_M TVDLRVIRPLCPVSISG--------------------------------A
MAB_4758|M.abscessus_ATCC_1997 SVDLRVVPGLCPVRTSP--------------------------------A
TH_4049|M.thermoresistible__bu SIELRGIPQPCPIAISP--------------------------------T
MSMEG_5743|M.smegmatis_MC2_155 DVAVHVLPSGQP--------------------------------------
:
Mb1092c|M.bovis_AF2122/97 PKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTCRSLEFHRAV
Rv1063c|M.tuberculosis_H37Rv PKMGSFEVMNRTIDIAQSALARHTLAGYPADLLIEVPRSTCRSLEFHRAV
MAV_1190|M.avium_104 PKLGSFEVMNRTIDIAQAALARHTLAVYPPDLLIEVPRSICRGLEFHRAV
Mflv_2030|M.gilvum_PYR-GCK PRLGSFEVMNRVIDIAQSALARHTLAAYPPDLLIEVPRTVCRSLDFHRAH
Mvan_4687|M.vanbaalenii_PYR-1 PKLGAFEVMNRVIDIAQAALARHTLAAYPPDLLIEVPRTVCRSLDFHRAT
MUL_1736|M.ulcerans_Agy99 DFSQSATLIPRPHQATREWLATNPARIGQAALLKPHLH------------
MMAR_2150|M.marinum_M DFSQSATLIPRSHQATREWLATNPARIGQAALLKPHLH------------
MAB_4758|M.abscessus_ATCC_1997 DFSHADELIGRAHEQTRRWLLMPRFKINQADLLEHHHG------------
TH_4049|M.thermoresistible__bu DFPHSAELIARSETLARKWLSTPHPATGQAAMLAPHCHGPNRA-------
MSMEG_5743|M.smegmatis_MC2_155 QRAAATWSNLRYRDSRRIGRRAEVAYDATREYLKALP-------------
: * : *
Mb1092c|M.bovis_AF2122/97 EVIAVGRALATQALEAFEIDDDESAAATIEG
Rv1063c|M.tuberculosis_H37Rv EVIAVGRALATQALEAFEIDDDESAAATIEG
MAV_1190|M.avium_104 EVIDAGRALADQALDALEDGDDDRPAVER--
Mflv_2030|M.gilvum_PYR-GCK EVIEIGQELASAALEALDPEPSEA-------
Mvan_4687|M.vanbaalenii_PYR-1 EVIEIGQELASAALDTLEQKVPETASDT---
MUL_1736|M.ulcerans_Agy99 -------------------------------
MMAR_2150|M.marinum_M -------------------------------
MAB_4758|M.abscessus_ATCC_1997 -------------------------------
TH_4049|M.thermoresistible__bu -------------------------------
MSMEG_5743|M.smegmatis_MC2_155 -------------------------------