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M. thermoresistible (build 8) TH_1491 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2812711 - 2813634
length: 308

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1491-100% (308)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1091-7e-8766.67% (252) hypothetical protein Mb1091
M. gilvum PYR-GCKMflv_2029-2e-8764.31% (269) patatin
M. tuberculosis H37RvRv1062-7e-8766.67% (252) hypothetical protein Rv1062
M. leprae Br4923MLBr_00482ruvA8e-1460.61% (66) Holliday junction DNA helicase RuvA
M. abscessus ATCC 19977MAB_2883c-1e-0961.54% (52) Holliday junction DNA helicase RuvA
M. marinum MMMAR_4404-3e-9168.36% (256) hypothetical protein MMAR_4404
M. avium 104MAV_1189-5e-8565.62% (256) phospholipase, patatin family protein
M. smegmatis MC2 155MSMEG_5285-6e-8557.89% (285) phospholipase, patatin family protein
M. ulcerans Agy99MUL_1715ruvA3e-1769.35% (62) Holliday junction DNA helicase RuvA
M. vanbaalenii PYR-1Mvan_4688-4e-8562.64% (265) patatin

CLUSTAL 2.0.9 multiple sequence alignment


Mb1091|M.bovis_AF2122/97            MTTR-RALVLAGGGLAGIAWETGVLRGIADESPAAARLLLDSDVLVGTSA
Rv1062|M.tuberculosis_H37Rv         MTTR-RALVLAGGGLAGIAWETGVLRGIADESPAAARLLLDSDVLVGTSA
MMAR_4404|M.marinum_M               MAPK-RALVLAGGGLAGIAWETGVLLGIADESPAAARLLLDSDVLVGTSA
MAV_1189|M.avium_104                MTTK-RALVLAGGGIAGIAWETGVLRGIADESPAAARLLTESDVLVGTSA
MSMEG_5285|M.smegmatis_MC2_155      MDSK-RALVLAGGGIAGIAWETGILRGIADESPETAQALLGSDVLVGTSA
Mflv_2029|M.gilvum_PYR-GCK          MSGT-RALVLAGGGLAGIAWETGVLLGILEEAPEVGRQLLDSDVLVGTSA
Mvan_4688|M.vanbaalenii_PYR-1       MTDVNRALVLAGGGLAGIAWETGVLLGICDESPDAGQKLLAADVLLGTSA
TH_1491|M.thermoresistible__bu      VANR-RALVLAGGGLAGIAWETGVLLGIADESPHTADLLLTSDVLVGTSA
MLBr_00482|M.leprae_Br4923          ------MIFSVRGEVLEVALDHAVIEAAG--------------IGYRVNA
MUL_1715|M.ulcerans_Agy99           ------MISSLRGEVLEVALDHVVIEAAG--------------VGYRVNA
MAB_2883c|M.abscessus_ATCC_199      ------MIASVNGEVIDIALDHVVIEAAG--------------VGYRVNA
                                           :    * :  :* :  :: .                :   ..*

Mb1091|M.bovis_AF2122/97            GATVAAQISSGCPLDTLYERQLAETS--AEIDPGVDIDAITDLFLTAVTE
Rv1062|M.tuberculosis_H37Rv         GATVAAQISSGCPLDTLYERQLAETS--AEIDPGVDIDAITDLFLTAVTE
MMAR_4404|M.marinum_M               GSAVAAQISSGTSLDALFDRQIAEQS--AELDPGVDIDVITELFLDALRE
MAV_1189|M.avium_104                GSAVAAQLCSGHTLDALFDRQVAASS--PEIDSGVDVEAITELFLTALAE
MSMEG_5285|M.smegmatis_MC2_155      GSTVAAQLSSGLSLDELYERQVGDAS--AELAPTAGIGTISELFVDAMLT
Mflv_2029|M.gilvum_PYR-GCK          GSTVAAQLGSGMGLTELFERQRSESHGAHEIHPGVSIDAITDLFLKAMTI
Mvan_4688|M.vanbaalenii_PYR-1       GSAVAAQVGSGVPLEELFARQLSEEHGAHEIHPGVSIDAITDLFLDAMLT
TH_1491|M.thermoresistible__bu      GSAVAAQLGSGAPLTRLFERQLDPNT--AEIKPRVAIDDLTAEFLEAVRR
MLBr_00482|M.leprae_Br4923          TPSALATLRQGSQARLVTAMVVREDS---MTLYGFSDAENRDLFLALLSV
MUL_1715|M.ulcerans_Agy99           TPSTLATLRQGTDARLITAMIVREDS---MTLYGFVDGETRDLFLTLLSV
MAB_2883c|M.abscessus_ATCC_199      TPATLSTLRRGTQIRLITAMIVREDS---MTLYGFTDTDARDLFTTLLGV
                                     .:. : :  *     :                          *   :  

Mb1091|M.bovis_AF2122/97            PHIS----TRRRLQRIGAVALAVDTVPESVRRQVIAQRLPSHDWP-DRVL
Rv1062|M.tuberculosis_H37Rv         PHIS----TRRRLQRIGAVALAVDTVPESVRRQVIAQRLPSHDWP-DRVL
MMAR_4404|M.marinum_M               PRIPGVDKIRLRLQRIGSVALATETVSESVRREVIAARLPCHDWP-DRAL
MAV_1189|M.avium_104                PYDDSEDKTRQQLRRIGAVALATDTVPAPVRRRVIAARLPSHRWP-RRAL
MSMEG_5285|M.smegmatis_MC2_155      PGTT----KAQKLRRIGEIAAQTQTVPESVRREVIAARLPSHEWPQERIL
Mflv_2029|M.gilvum_PYR-GCK          PDAT----REQKLQKIGAVAAGTDTVGEAVRRKVIEHRLPSHDWP-ARIL
Mvan_4688|M.vanbaalenii_PYR-1       QGAT----KAQKLAKIGCVAAETDTVPEAVRRTVIEHRLPAHEWP-QRAL
TH_1491|M.thermoresistible__bu      PGST-----VEKLRRIGAVALSTGTVGEAERRAVIAARLPAHDWP-DRDL
MLBr_00482|M.leprae_Br4923          SGVG------------PRLAMATLAVHDAA-----ALRQALADSDVASLT
MUL_1715|M.ulcerans_Agy99           SGVG------------PRLAMATLSVHDAN-----GLRQALADGDVTALT
MAB_2883c|M.abscessus_ATCC_199      SGVG------------PKIAMATLAVYDAP-----TLRQALADGDVAALT
                                                      :*  . :*  .        * .          

Mb1091|M.bovis_AF2122/97            RVTAIDIATGELVVFHRESNVALVDAVAASCSVPGAWPPVTIAGRRYMDG
Rv1062|M.tuberculosis_H37Rv         RVTAIDIATGELVVFHRESNVALVDAVAASCSVPGAWPPVTIAGRRYMDG
MMAR_4404|M.marinum_M               RVTAIDVSTGELVAFDRDSGVELVDAVAASCAVPGAWPPVTIAGRRYMDG
MAV_1189|M.avium_104                RLTAIDVDTGELTVFDPASGVDLVDAVAASCAVPGAWPPVAIGGRRYMDG
MSMEG_5285|M.smegmatis_MC2_155      RIAAIDIATGELVGFDRHSGVDLVDAVAASCAVPGAWPPVTIGDRRYIDG
Mflv_2029|M.gilvum_PYR-GCK          RVTAIDIATGELVVLDASSGVTLVDAVAASCAVPGVWPPVTIGERRFMDG
Mvan_4688|M.vanbaalenii_PYR-1       RVTAIDIATGELVVFDAASGVGLVDAVAASCAVPGVWPPVTIGGRRFMDG
TH_1491|M.thermoresistible__bu      RLSAVDVGTGELVCFDRDSGVPLVDAVAASCAVPGVWPPVTIGERRYMDG
MLBr_00482|M.leprae_Br4923          RVPGIGKRGAERIVLELR---DKVGPVGASGLTVGTAADGNAVRGSVVEA
MUL_1715|M.ulcerans_Agy99           RVPGIGKRGAERMVVELR---DKVGPAGSA--ATAPAVNGHTVRAPVVEA
MAB_2883c|M.abscessus_ATCC_199      RVPGIGKRGAERLVLELR---EKVAAAPGGTTELGRGT-ASLVRSQVVEA
                                    *:..:.   .*   ..       * .. ..    .            ::.

Mb1091|M.bovis_AF2122/97            GVASSVNLGVADDCDAAVVLVPAGADAPSPFG-GGAAAEIAAATGMVFAV
Rv1062|M.tuberculosis_H37Rv         GVASSVNLGVADDCDAAVVLVPAGADAPSPFG-GGAAAEIAAATGMVFAV
MMAR_4404|M.marinum_M               GVASLVNLGVADDCGVAVVLVPTGADAPSPFG-GGSAAEVAEFAGTSLGV
MAV_1189|M.avium_104                GVASSVNLGVAADCDVAVVLVPSGVDAPSPFG-AGPAAEIAAFPGRALAV
MSMEG_5285|M.smegmatis_MC2_155      GVSSSINLELAVDCQTAVVFIPAGQSAPSPFDPGGIAEEISEFPGAALSI
Mflv_2029|M.gilvum_PYR-GCK          GVGSTVNMSAAVDCAAAVALVPSPADSPSPWG-AGTAAEIEAFPGEALAV
Mvan_4688|M.vanbaalenii_PYR-1       GVGSTVNMSAVQDCGAAVVLVPSGANSPSPWG-TGTVAEIEGFPGATLAV
TH_1491|M.thermoresistible__bu      GVASTVNMALAADCDTVVALVPSRRDTPSPFG-PGPAREIDEFGGAAVGV
MLBr_00482|M.leprae_Br4923          LVGLGFAAKQAEEATDQVLDGELGKDGAVATS---------SALRAALSL
MUL_1715|M.ulcerans_Agy99           LVGLGFAAKQAEEATDKVLAG----DGEATTS---------SALRAALSL
MAB_2883c|M.abscessus_ATCC_199      LIGLGFAAKQAEQATDTVLAQDNPGDTGADVS---------GVLRSALAL
                                     :.  .    . :.   *       .     .               ..:

Mb1091|M.bovis_AF2122/97            FADDDSLAAFGPNPLDPLCR--VNSAMAGRQQGRREAQAVARLLGV----
Rv1062|M.tuberculosis_H37Rv         FADDDSLAAFGPNPLDPLCR--VNSAMAGRQQGRREAQAVARLLGV----
MMAR_4404|M.marinum_M               FADDDSLAAFGANPLDPRCR--KASALAGRAQGRREASAVAAFLGL----
MAV_1189|M.avium_104                FADDRSLAAFGPNPLDPGCR--VPSARAGREQGRREAAAVAEFLGV----
MSMEG_5285|M.smegmatis_MC2_155      YADDDSLDAFGSNPLDPACR--IPSARAGRAQGRREAREIAEFLEELAV-
Mflv_2029|M.gilvum_PYR-GCK          FADDDALAAFGPNPLDPACR--APAAEAGRVQGRREAARVADFLSGL---
Mvan_4688|M.vanbaalenii_PYR-1       FADDESLAAFGANPLDPACR--APAAQAGRAQGRREARKVAEFLSV----
TH_1491|M.thermoresistible__bu      FADDASVAAFGXXXGGHAVRGPVVEALVGLGFSAKQAEEATDKVLADDPD
MLBr_00482|M.leprae_Br4923          LGKTR---------------------------------------------
MUL_1715|M.ulcerans_Agy99           LGKAR---------------------------------------------
MAB_2883c|M.abscessus_ATCC_199      LGKTR---------------------------------------------
                                     ..                                               

Mb1091|M.bovis_AF2122/97            -----------------
Rv1062|M.tuberculosis_H37Rv         -----------------
MMAR_4404|M.marinum_M               -----------------
MAV_1189|M.avium_104                -----------------
MSMEG_5285|M.smegmatis_MC2_155      -----------------
Mflv_2029|M.gilvum_PYR-GCK          -----------------
Mvan_4688|M.vanbaalenii_PYR-1       -----------------
TH_1491|M.thermoresistible__bu      ASTSTALRSALSMLGRK
MLBr_00482|M.leprae_Br4923          -----------------
MUL_1715|M.ulcerans_Agy99           -----------------
MAB_2883c|M.abscessus_ATCC_199      -----------------