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VNCIHPTPDEPGFATSEMLYIDPAACVDCGACVSACPVGAIAPDNRLDDKQLPFVEINASFYPKRPAGQK LPPTSKLAPVIPAVPVRPRGRPLTVAIVGSGPAAMYAADELLTQDGVRVNVFEKLPTPYGLVRAGVAPDH QNTKKVTRLFDRVAGHDRFRFYLNVEVGKHLSHADLLAHHHAVLYAVGAPDDRRLDIEGMGLAGSGTATE LVAWINGHPEFTALPVDLRHERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVIA ARRGPAQSAFTLPELIGLTGSREVVLSAADRELVAADLANASDALTKAKLEVLSTLGDAAAPSERPRIRL AYRLTPDRILGEQRVTGVQFTLTGTDETHCLPTGLVLTSIGYRGKPIRDLPYDEAAAVVPNDGGRVVDPA SRRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADFNAGELADPAAKPEALTALVRARRPDAIDAA GWRAIDAAEIARGSADGRPRNKFTDIGDMLAAAAAAEPAPPPRRRLLARLVPSGRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1015 | - | - | 100% (546) | ferredoxin/ferredoxin--NADP reductase |
| M. avium 104 | MAV_5072 | - | e-117 | 46.23% (517) | NADPH-ferredoxin reductase fpra |
| M. avium 104 | MAV_4007 | - | 3e-89 | 44.54% (458) | NADPH-ferredoxin reductase fpra |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0910 | fprB | 0.0 | 77.74% (548) | NADPH:adrenodoxin oxidoreductase FprB |
| M. gilvum PYR-GCK | Mflv_1720 | - | 0.0 | 70.79% (541) | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0886 | fprB | 0.0 | 77.74% (548) | NADPH:adrenodoxin oxidoreductase FprB |
| M. leprae Br4923 | MLBr_02134 | fprB | 0.0 | 76.21% (538) | ferredoxin, ferredoxin-NADP reductase |
| M. abscessus ATCC 19977 | MAB_0930 | - | 1e-172 | 58.44% (539) | putative ferredoxin/ferredoxin--NADP reductase |
| M. marinum M | MMAR_4646 | fprB | 0.0 | 80.11% (533) | NADPH:adrenodoxin oxidoreductase FprB |
| M. smegmatis MC2 155 | MSMEG_5681 | - | 0.0 | 75.42% (541) | ferredoxin/ferredoxin--NADP reductase |
| M. thermoresistible (build 8) | TH_1806 | - | 0.0 | 73.58% (545) | probable ferredoxin/ferredoxin--NADP reductase |
| M. ulcerans Agy99 | MUL_0264 | fprB | 0.0 | 79.26% (540) | NADPH:adrenodoxin oxidoreductase FprB |
| M. vanbaalenii PYR-1 | Mvan_5031 | - | 0.0 | 74.12% (541) | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0910|M.bovis_AF2122/97 MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
Rv0886|M.tuberculosis_H37Rv MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
MMAR_4646|M.marinum_M MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
MUL_0264|M.ulcerans_Agy99 MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVTCVDCG
MLBr_02134|M.leprae_Br4923 MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
MAV_1015|M.avium_104 --------------------MNCIHPTPDEPGFATSEMLYIDPAACVDCG
MSMEG_5681|M.smegmatis_MC2_155 MPHVITQSCCSDGSCVYACPVNCIHPSPDEPGFATAEMLYIDPDACVDCG
TH_1806|M.thermoresistible__bu ---VITQSCCSDASCVYACPVNCIHPTPDEPGFATTEMLYIDPVACVDCG
Mflv_1720|M.gilvum_PYR-GCK MPHVITQSCCSDGSCVYACPVNCIHPSPDEPGFATAEMLYIDPVACVDCG
Mvan_5031|M.vanbaalenii_PYR-1 MPHVITQSCCSDGSCVYACPVNCIHPTPDEPGFATAEMLYIDPVACVDCG
MAB_0930|M.abscessus_ATCC_1997 --------------------MNCIHPTPDEPDFLKAEMLHIDASACVDCG
:*****:****.* .:***:**. :*****
Mb0910|M.bovis_AF2122/97 ACVTACPVSAIAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPV
Rv0886|M.tuberculosis_H37Rv ACVTACPVSAIAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPV
MMAR_4646|M.marinum_M ACVSACPVGAIAPDSRLDSKQLPFVEINASYYPQRQGGEKLPPTSKLAPV
MUL_0264|M.ulcerans_Agy99 ACVSACPVGAIAPDSRLDSKQLPFVEINASYYPQRQGGEKLPPTSKLAPV
MLBr_02134|M.leprae_Br4923 ACVSACPVGAIASDTRLAPKQLPFIEINASYYPARPIDLKLPPTSKLAPV
MAV_1015|M.avium_104 ACVSACPVGAIAPDNRLDDKQLPFVEINASFYPKRPAGQKLPPTSKLAPV
MSMEG_5681|M.smegmatis_MC2_155 ACVSACPVGAIAPDTRLEPRQLPFVEINAAFYPKRE--GKLPPTSKLAPV
TH_1806|M.thermoresistible__bu ACVTACPVGAIAPDHRLDATQRPFIELNAAFYPPRDPDEKLPPTSKLAPV
Mflv_1720|M.gilvum_PYR-GCK ACVSACPVGAIAPDSKLTPEQLPFVELNAAFYPKRE--GKLPPTSKLAPV
Mvan_5031|M.vanbaalenii_PYR-1 ACVSACPVGAIAPETGLAPDQLPFVELNAAFYPKRD--GKLPPTSKLAPV
MAB_0930|M.abscessus_ATCC_1997 ACVAACPVDAIKPDSTLKEEQLPFLRINSEFYPREI------PRASLAPV
***:****.** .: * * **:.:*: :** . * :.****
Mb0910|M.bovis_AF2122/97 TPAAEVRVR-RQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPY
Rv0886|M.tuberculosis_H37Rv TPAAEVRVR-RQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPY
MMAR_4646|M.marinum_M IPAAQVRPR-SQPLTVAIVGSGPAAMYAADELLVQHGVCVNVFEKLPTPY
MUL_0264|M.ulcerans_Agy99 IPAAQVRPR-SQPLTVAIVGSGPAAMYAADELLVQHGVRVNVFEKLPTPY
MLBr_02134|M.leprae_Br4923 IPAAQVHVR-RRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPY
MAV_1015|M.avium_104 IPAVPVRPR-GRPLTVAIVGSGPAAMYAADELLTQDGVRVNVFEKLPTPY
MSMEG_5681|M.smegmatis_MC2_155 IEAPKITR--DGPLTVAIVGSGPAAMYAADELLTQRGVRVNVFEKLPTPY
TH_1806|M.thermoresistible__bu IPAPRIERR-GGPLRVAIVGSGPAAMYAADELLTQDDVLVNVFERLPTPY
Mflv_1720|M.gilvum_PYR-GCK LEAPVVHRKSGGPLTVAIVGSGPAAMYAADELLTQPDVRVNVFEKLPTRY
Mvan_5031|M.vanbaalenii_PYR-1 LEAPEVRRRPGGPLTVAIVGSGPAAMYAADELLTQQGVRVNVFEKLPTPY
MAB_0930|M.abscessus_ATCC_1997 IQAPPVRGT--SALKVAIVGSGPAAMYAADELLTQPNVKVNMFERLPAPY
* : .* **:***************.* .* **:**:**: *
Mb0910|M.bovis_AF2122/97 GLVRSGVAPDHQNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAH
Rv0886|M.tuberculosis_H37Rv GLVRSGVAPDHQNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAH
MMAR_4646|M.marinum_M GLVRAGVAPDHQNTKRVTRLFDRVARHRRFRFYLNVEIGRKLSHADLLAH
MUL_0264|M.ulcerans_Agy99 GLVRAGVAPDHQNTKRVTRLFDRVARHRRFRFYLNVEIGRQLSHADLLAH
MLBr_02134|M.leprae_Br4923 GLVRAGLAPDHQNTKKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAH
MAV_1015|M.avium_104 GLVRAGVAPDHQNTKKVTRLFDRVAGHDRFRFYLNVEVGKHLSHADLLAH
MSMEG_5681|M.smegmatis_MC2_155 GLVRAGVAPDHQSTKRVTELFDRMAAQRGFTFYLNVEVGKHLTHADLLGH
TH_1806|M.thermoresistible__bu GLVRAGVAPDHQKTKGVTDLFDKIAQQPGFEFYLNVEVGTHLSHAELLAH
Mflv_1720|M.gilvum_PYR-GCK GLVRAGVAPDHQHTKRVTELFDTIADKPGFTFFLNTEVGSDLTHDELLRY
Mvan_5031|M.vanbaalenii_PYR-1 GLVRAGVAPDHQHTKRVTKLFESISGLPGFTLYLNVEVGADLTHDELLAH
MAB_0930|M.abscessus_ATCC_1997 GLVRAGVAPDHQQTKRVTKLFDTMAAQPNFEFFLNVEVGKDITHEELLAH
****:*:***** ** ** **: :: * ::**.*:* .: * :** :
Mb0910|M.bovis_AF2122/97 HHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPDFNDLPVDLS
Rv0886|M.tuberculosis_H37Rv HHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPDFNDLPVDLS
MMAR_4646|M.marinum_M HHAVVYAVGAPDDRRLHIDGMGLPGTGTATELVAWINGHPDFTDLPVDLS
MUL_0264|M.ulcerans_Agy99 HHAVVYAVGAPDDRRLHIDGMGLPGTGTATELVAWINGHPDFTDLPVDLS
MLBr_02134|M.leprae_Br4923 HHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPDFAYLPVDLS
MAV_1015|M.avium_104 HHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPEFTALPVDLR
MSMEG_5681|M.smegmatis_MC2_155 HHAVVYAVGAPNDRRLDIEGMDLPGTATATEVVAWINGHPDHTDLPVRLD
TH_1806|M.thermoresistible__bu HHAVLYAVGAPNDRRLDIDGMGLPGTGTATEVVAWYNGHPDFADLPVDLS
Mflv_1720|M.gilvum_PYR-GCK HHAVLYAVGAPSDRRLDIDGMELPGTATATDLVAWYNGHPEAADLRVDLH
Mvan_5031|M.vanbaalenii_PYR-1 HHAVLYAVGAPDDRRLDIDGIGRPGTATATEVVAWYNGHPEFAHLPVDLS
MAB_0930|M.abscessus_ATCC_1997 HHAVIYSVGASSDRRLDIPGIELPGNATATQVVAWINAHPDYADFRVDLD
****:*:***..**** * *: .*..***::*** *.**: : * *
Mb0910|M.bovis_AF2122/97 HERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVV
Rv0886|M.tuberculosis_H37Rv HERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVV
MMAR_4646|M.marinum_M HERAVIIGNGNVALDVARMLTANPDDLARTDIADPALRALRNSAVREVVI
MUL_0264|M.ulcerans_Agy99 HERAVITGNGNVALDVARMLTANPDDLARTDIADPALRALRNSAVREVVI
MLBr_02134|M.leprae_Br4923 HERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVV
MAV_1015|M.avium_104 HERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVI
MSMEG_5681|M.smegmatis_MC2_155 HERVVIVGNGNVALDVARVLTSDPDALARTDISDHALAALRSSAVQEVVI
TH_1806|M.thermoresistible__bu GDRVVIVGNGNVALDVARILTADPDELARTDIADHALAALRSSRVREVVI
Mflv_1720|M.gilvum_PYR-GCK TERVVVIGNGNVALDVARILTTDPDALARTDIADHALARLRDSQVREVVV
Mvan_5031|M.vanbaalenii_PYR-1 GDRVVIIGNGNVALDVARILTAEPDVLARTDIADHALAVLRDSRVREVVI
MAB_0930|M.abscessus_ATCC_1997 HERAVVIGNGNVALDVARVLTGDVERLARTDISDTALTALRSSKLREVVI
:*.*: ***********:*: : . ** ***:: ** * .* ::***:
Mb0910|M.bovis_AF2122/97 AARRGPAHSAFTLPELIGLTAG--ADVVLDPGDHQRVLDDLAIVADPLTR
Rv0886|M.tuberculosis_H37Rv AARRGPAHSAFTLPELIGLTAG--ADVVLDPGDHQRVLDDLAIVADPLTR
MMAR_4646|M.marinum_M AARRGPAHSAFTLPELIGLTGC--AEVVLDAADRQRVLDDLATVSDQLTK
MUL_0264|M.ulcerans_Agy99 AARRGPAHSAFTLPELIGLTGC--AEVVLDAADRQRVLDDLATVSDQLTK
MLBr_02134|M.leprae_Br4923 AARRGPAHSAFTLPELIGLKAT--SEVVLDAGDRKLVEGDFATVSDSLTR
MAV_1015|M.avium_104 AARRGPAQSAFTLPELIGLTGS--REVVLSAADRELVAADLANASDALTK
MSMEG_5681|M.smegmatis_MC2_155 AARRGPAASAFTLPELIGLTST--CDVVLDSADHDLVLRDLAQETDPLTR
TH_1806|M.thermoresistible__bu AARRGPADSAFTLPELIGLTAT--ADVVLDARDHELVDRDLARTTDSLTR
Mflv_1720|M.gilvum_PYR-GCK AARRGPAAAAFTLPELIGLTSS--CDVVLDPADHDSVLAELAEATDPLTR
Mvan_5031|M.vanbaalenii_PYR-1 AARRGPAASSFTLPELIGLTST--CEVVLDPADHERVLTDLAAATDPLTR
MAB_0930|M.abscessus_ATCC_1997 VGRRGPEHSAFTLPELLGLVGLPDMTVVVDQETADLVDQALQTHLEPLTR
..**** ::******:** . **:. . * : : **:
Mb0910|M.bovis_AF2122/97 NKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQ-----RRAGGVQ
Rv0886|M.tuberculosis_H37Rv NKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQ-----RRAGGVQ
MMAR_4646|M.marinum_M RKLEILATLGEGS-AASGP---RIRLAYQLTPRSVRGE-----QRVSGVE
MUL_0264|M.ulcerans_Agy99 RKLEILATLGEGS-AASGP---RIRLAYQLTPRSVRGE-----QRASGVE
MLBr_02134|M.leprae_Br4923 KKLEVLSSLVDSSKPTSRR---RIRLAYQLTPKRVLGN-----QRATGVE
MAV_1015|M.avium_104 AKLEVLSTLGDAAAPSERP---RIRLAYRLTPDRILGE-----QRVTGVQ
MSMEG_5681|M.smegmatis_MC2_155 NKLEILAKLGDASAPITRP---RIRFAYQLTPRRVLGE-----NQVTAVE
TH_1806|M.thermoresistible__bu NKLEILAKLPDAAAPITRP---RIRFAYQLTPRAILRAGAPAADRAAGIE
Mflv_1720|M.gilvum_PYR-GCK NKLEILSTLGDTTAPVTRP---RIRLAYQLTPRRITGD-----ARAAGVE
Mvan_5031|M.vanbaalenii_PYR-1 SKLEIMSKLGDATAPVTRP---RIRLAYRLTPRRVLGE-----ERATGVQ
MAB_0930|M.abscessus_ATCC_1997 QKLEVLSTCPREAREPGGK---TIRFAYNRTPARVLGE-----DRVEAIE
***:::. : **:**. ** : :. .::
Mb0910|M.bovis_AF2122/97 FSVTGTDELRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDP
Rv0886|M.tuberculosis_H37Rv FSVTGTDELRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDP
MMAR_4646|M.marinum_M FSVTGTDEMRTLDAGLVLTSIGYRGKKIGDLPFDDNAAVVPNDGGRVVDP
MUL_0264|M.ulcerans_Agy99 FSVTGTDEMRTLDAGLVLTSIGYRGTKIGDLPFDDNAAVVRNDGGRVVDP
MLBr_02134|M.leprae_Br4923 FSVTGTEESRRFDAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDP
MAV_1015|M.avium_104 FTLTGTDETHCLPTGLVLTSIGYRGKPIRDLPYDEAAAVVPNDGGRVVDP
MSMEG_5681|M.smegmatis_MC2_155 FGVTGTDEVRTLDAGLLLTSIGYRGKAIADLPFDEDASVVPNDGGRVIDP
TH_1806|M.thermoresistible__bu FVRTGTDEVCRLDAGLVLTSIGYRGRPIRDLPFDDTAAVVPNDGGRVVDP
Mflv_1720|M.gilvum_PYR-GCK FTVTGGDEVVEISAGLVLTSIGYRGTPIRGLPFDADAAVVPNDGGRVIA-
Mvan_5031|M.vanbaalenii_PYR-1 FDVTGTGETCELTAGLVLTSIGYRGKPIRGLPFDEAAAVVPNAGGRVVDP
MAB_0930|M.abscessus_ATCC_1997 FQHGDTTDT--IKAGLFLTSIGYRGVPMPDVPFDSQRGTIPNEQGRVKDS
* . : : :**.***:**** : .:*:* . : * ***
Mb0910|M.bovis_AF2122/97 GTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALVADFNDGRLTDPV
Rv0886|M.tuberculosis_H37Rv GTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALVADFNDGRLTDPV
MMAR_4646|M.marinum_M VRGAPVPGVYVAGWIKRGPSGFIGTNKSCSLQTVAALVADFNAGKLGDPV
MUL_0264|M.ulcerans_Agy99 VRGAPVPGVYVAGWIKRGPSGFIGTNKSCSLQTVAALVADFNAGKLGDPV
MLBr_02134|M.leprae_Br4923 SRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADFNAGWLTDPV
MAV_1015|M.avium_104 ASRRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADFNAGELADPA
MSMEG_5681|M.smegmatis_MC2_155 ATGAPVPGAYVAGWIKRGPTGFIGTNKSCAAQTVHHLVDDYNAGALTDPP
TH_1806|M.thermoresistible__bu ATGRPVPGSYVAGWIKRGPTGFIGTNKSCAAETVHKLVDDYNAGLLTEPI
Mflv_1720|M.gilvum_PYR-GCK -GADPVRGSYVAGWIKRGPTGFIGTNKSCAAETVHNLVADYNDGLLADPV
Mvan_5031|M.vanbaalenii_PYR-1 ETGEPVRGSYVAGWIKRGPTGFIGTNKSCAAETVHHLAADYNAGLLADPS
MAB_0930|M.abscessus_ATCC_1997 STGQAHPGTYVAGWIKRGPTGFIGTNKSCSQQTVTSLVEDYNNGLLADPP
. * **********:******* *: :** :. *:* * * :*
Mb0910|M.bovis_AF2122/97 ATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEM
Rv0886|M.tuberculosis_H37Rv ATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEM
MMAR_4646|M.marinum_M CKPAALAKLVHTREPDVIDSAGWFAIDAAEIARGNGEGRPRNKFTDVADM
MUL_0264|M.ulcerans_Agy99 CKPAALAKLVHTREPDVIDSAGWFAIDAAEIARGNAEGRPRNKFTDVADM
MLBr_02134|M.leprae_Br4923 AEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADM
MAV_1015|M.avium_104 AKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSADGRPRNKFTDIGDM
MSMEG_5681|M.smegmatis_MC2_155 RKPSALDKLVRARQPDVVDAAGWRAIDAAEIARGGDD-RPRDKFTTVPEM
TH_1806|M.thermoresistible__bu HRPSALDKLVRSRRPDLVTAAGWRAIDAAEIDRGGQE-RPRVKFTGTDQM
Mflv_1720|M.gilvum_PYR-GCK HRGAALEHFVRGRRPAVIGTAGWKAIDEAEIARGAGV-RPREKFTSVAEM
Mvan_5031|M.vanbaalenii_PYR-1 HKASALDRFVRGRQPAVIDACGWRAIDAAEVARGAGL-RPRDKFTTVAEM
MAB_0930|M.abscessus_ATCC_1997 QRLSGLSKVIQRRQPTIIGHDGWLAIDRAEIARGKGAGRPRDKFVSVPEM
* .:: *.* : ** *** **: :* * * **. :*
Mb0910|M.bovis_AF2122/97 LAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL--
Rv0886|M.tuberculosis_H37Rv LAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL--
MMAR_4646|M.marinum_M LGAAASGA--PVRS-----SRGLLAGILGR-----
MUL_0264|M.ulcerans_Agy99 LGAAASGA--PVRP-----SRGLLAAILGR-----
MLBr_02134|M.leprae_Br4923 LAVAAGAP--PLR------LRALS-----------
MAV_1015|M.avium_104 LAAAAAAEPAPPPR------RRLLARLVPSGRG--
MSMEG_5681|M.smegmatis_MC2_155 LAVAVTAPKPSVR-------QRLTAGLLG------
TH_1806|M.thermoresistible__bu LAVARTAPAPPLR-------QRLLAALRQPLTGVV
Mflv_1720|M.gilvum_PYR-GCK VEVAANAPAPPIH-------RRVLAALRR------
Mvan_5031|M.vanbaalenii_PYR-1 ENVAAAAAAPPMS-------KRLLEALRR------
MAB_0930|M.abscessus_ATCC_1997 LRVAADAPQPPLWR------KAIRGSALEDLLR--
.* . . : :