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PHVITQSCCSDGSCVYACPVNCIHPTPDEPGFATAEMLYIDPVACVDCGACVSACPVGAIAPETGLAPDQ LPFVELNAAFYPKRDGKLPPTSKLAPVLEAPEVRRRPGGPLTVAIVGSGPAAMYAADELLTQQGVRVNVF EKLPTPYGLVRAGVAPDHQHTKRVTKLFESISGLPGFTLYLNVEVGADLTHDELLAHHHAVLYAVGAPDD RRLDIDGIGRPGTATATEVVAWYNGHPEFAHLPVDLSGDRVVIIGNGNVALDVARILTAEPDVLARTDIA DHALAVLRDSRVREVVIAARRGPAASSFTLPELIGLTSTCEVVLDPADHERVLTDLAAATDPLTRSKLEI MSKLGDATAPVTRPRIRLAYRLTPRRVLGEERATGVQFDVTGTGETCELTAGLVLTSIGYRGKPIRGLPF DEAAAVVPNAGGRVVDPETGEPVRGSYVAGWIKRGPTGFIGTNKSCAAETVHHLAADYNAGLLADPSHKA SALDRFVRGRQPAVIDACGWRAIDAAEVARGAGLRPRDKFTTVAEMENVAAAAAAPPMSKRLLEALRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5031 | - | - | 100% (559) | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1910 | - | 8e-89 | 42.45% (457) | FAD-dependent pyridine nucleotide-disulphide oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5697 | gltD | 3e-15 | 28.84% (267) | glutamate synthase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0910 | fprB | 0.0 | 73.23% (564) | NADPH:adrenodoxin oxidoreductase FprB |
| M. gilvum PYR-GCK | Mflv_1720 | - | 0.0 | 80.14% (559) | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0886 | fprB | 0.0 | 73.23% (564) | NADPH:adrenodoxin oxidoreductase FprB |
| M. leprae Br4923 | MLBr_02134 | fprB | 0.0 | 70.13% (559) | ferredoxin, ferredoxin-NADP reductase |
| M. abscessus ATCC 19977 | MAB_0930 | - | 1e-173 | 58.29% (537) | putative ferredoxin/ferredoxin--NADP reductase |
| M. marinum M | MMAR_4646 | fprB | 0.0 | 71.43% (560) | NADPH:adrenodoxin oxidoreductase FprB |
| M. avium 104 | MAV_1015 | - | 0.0 | 74.12% (541) | ferredoxin/ferredoxin--NADP reductase |
| M. smegmatis MC2 155 | MSMEG_5681 | - | 0.0 | 77.38% (557) | ferredoxin/ferredoxin--NADP reductase |
| M. thermoresistible (build 8) | TH_1806 | - | 0.0 | 75.84% (563) | probable ferredoxin/ferredoxin--NADP reductase |
| M. ulcerans Agy99 | MUL_0264 | fprB | 0.0 | 71.25% (560) | NADPH:adrenodoxin oxidoreductase FprB |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0910|M.bovis_AF2122/97 MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
Rv0886|M.tuberculosis_H37Rv MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
MMAR_4646|M.marinum_M MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
MUL_0264|M.ulcerans_Agy99 MPHVITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVTCVDCG
MLBr_02134|M.leprae_Br4923 MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCG
MAV_1015|M.avium_104 --------------------MNCIHPTPDEPGFATSEMLYIDPAACVDCG
Mvan_5031|M.vanbaalenii_PYR-1 MPHVITQSCCSDGSCVYACPVNCIHPTPDEPGFATAEMLYIDPVACVDCG
Mflv_1720|M.gilvum_PYR-GCK MPHVITQSCCSDGSCVYACPVNCIHPSPDEPGFATAEMLYIDPVACVDCG
MSMEG_5681|M.smegmatis_MC2_155 MPHVITQSCCSDGSCVYACPVNCIHPSPDEPGFATAEMLYIDPDACVDCG
TH_1806|M.thermoresistible__bu ---VITQSCCSDASCVYACPVNCIHPTPDEPGFATTEMLYIDPVACVDCG
MAB_0930|M.abscessus_ATCC_1997 --------------------MNCIHPTPDEPDFLKAEMLHIDASACVDCG
:*****:****.* .:***:**. :*****
Mb0910|M.bovis_AF2122/97 ACVTACPVSAIAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPV
Rv0886|M.tuberculosis_H37Rv ACVTACPVSAIAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPV
MMAR_4646|M.marinum_M ACVSACPVGAIAPDSRLDSKQLPFVEINASYYPQRQGGEKLPPTSKLAPV
MUL_0264|M.ulcerans_Agy99 ACVSACPVGAIAPDSRLDSKQLPFVEINASYYPQRQGGEKLPPTSKLAPV
MLBr_02134|M.leprae_Br4923 ACVSACPVGAIASDTRLAPKQLPFIEINASYYPARPIDLKLPPTSKLAPV
MAV_1015|M.avium_104 ACVSACPVGAIAPDNRLDDKQLPFVEINASFYPKRPAGQKLPPTSKLAPV
Mvan_5031|M.vanbaalenii_PYR-1 ACVSACPVGAIAPETGLAPDQLPFVELNAAFYPKRD--GKLPPTSKLAPV
Mflv_1720|M.gilvum_PYR-GCK ACVSACPVGAIAPDSKLTPEQLPFVELNAAFYPKRE--GKLPPTSKLAPV
MSMEG_5681|M.smegmatis_MC2_155 ACVSACPVGAIAPDTRLEPRQLPFVEINAAFYPKRE--GKLPPTSKLAPV
TH_1806|M.thermoresistible__bu ACVTACPVGAIAPDHRLDATQRPFIELNAAFYPPRDPDEKLPPTSKLAPV
MAB_0930|M.abscessus_ATCC_1997 ACVAACPVDAIKPDSTLKEEQLPFLRINSEFYPREI------PRASLAPV
***:****.** .: * * **:.:*: :** . * :.****
Mb0910|M.bovis_AF2122/97 TPAAEVRVR-RQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPY
Rv0886|M.tuberculosis_H37Rv TPAAEVRVR-RQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPY
MMAR_4646|M.marinum_M IPAAQVRPR-SQPLTVAIVGSGPAAMYAADELLVQHGVCVNVFEKLPTPY
MUL_0264|M.ulcerans_Agy99 IPAAQVRPR-SQPLTVAIVGSGPAAMYAADELLVQHGVRVNVFEKLPTPY
MLBr_02134|M.leprae_Br4923 IPAAQVHVR-RRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPY
MAV_1015|M.avium_104 IPAVPVRPR-GRPLTVAIVGSGPAAMYAADELLTQDGVRVNVFEKLPTPY
Mvan_5031|M.vanbaalenii_PYR-1 LEAPEVRRRPGGPLTVAIVGSGPAAMYAADELLTQQGVRVNVFEKLPTPY
Mflv_1720|M.gilvum_PYR-GCK LEAPVVHRKSGGPLTVAIVGSGPAAMYAADELLTQPDVRVNVFEKLPTRY
MSMEG_5681|M.smegmatis_MC2_155 IEAPKITR--DGPLTVAIVGSGPAAMYAADELLTQRGVRVNVFEKLPTPY
TH_1806|M.thermoresistible__bu IPAPRIERR-GGPLRVAIVGSGPAAMYAADELLTQDDVLVNVFERLPTPY
MAB_0930|M.abscessus_ATCC_1997 IQAPPVRGT--SALKVAIVGSGPAAMYAADELLTQPNVKVNMFERLPAPY
* : .* **:***************.* .* **:**:**: *
Mb0910|M.bovis_AF2122/97 GLVRSGVAPDHQNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAH
Rv0886|M.tuberculosis_H37Rv GLVRSGVAPDHQNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAH
MMAR_4646|M.marinum_M GLVRAGVAPDHQNTKRVTRLFDRVARHRRFRFYLNVEIGRKLSHADLLAH
MUL_0264|M.ulcerans_Agy99 GLVRAGVAPDHQNTKRVTRLFDRVARHRRFRFYLNVEIGRQLSHADLLAH
MLBr_02134|M.leprae_Br4923 GLVRAGLAPDHQNTKKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAH
MAV_1015|M.avium_104 GLVRAGVAPDHQNTKKVTRLFDRVAGHDRFRFYLNVEVGKHLSHADLLAH
Mvan_5031|M.vanbaalenii_PYR-1 GLVRAGVAPDHQHTKRVTKLFESISGLPGFTLYLNVEVGADLTHDELLAH
Mflv_1720|M.gilvum_PYR-GCK GLVRAGVAPDHQHTKRVTELFDTIADKPGFTFFLNTEVGSDLTHDELLRY
MSMEG_5681|M.smegmatis_MC2_155 GLVRAGVAPDHQSTKRVTELFDRMAAQRGFTFYLNVEVGKHLTHADLLGH
TH_1806|M.thermoresistible__bu GLVRAGVAPDHQKTKGVTDLFDKIAQQPGFEFYLNVEVGTHLSHAELLAH
MAB_0930|M.abscessus_ATCC_1997 GLVRAGVAPDHQQTKRVTKLFDTMAAQPNFEFFLNVEVGKDITHEELLAH
****:*:***** ** ** **: :: * ::**.*:* .: * :** :
Mb0910|M.bovis_AF2122/97 HHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPDFNDLPVDLS
Rv0886|M.tuberculosis_H37Rv HHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPDFNDLPVDLS
MMAR_4646|M.marinum_M HHAVVYAVGAPDDRRLHIDGMGLPGTGTATELVAWINGHPDFTDLPVDLS
MUL_0264|M.ulcerans_Agy99 HHAVVYAVGAPDDRRLHIDGMGLPGTGTATELVAWINGHPDFTDLPVDLS
MLBr_02134|M.leprae_Br4923 HHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPDFAYLPVDLS
MAV_1015|M.avium_104 HHAVLYAVGAPDDRRLDIEGMGLAGSGTATELVAWINGHPEFTALPVDLR
Mvan_5031|M.vanbaalenii_PYR-1 HHAVLYAVGAPDDRRLDIDGIGRPGTATATEVVAWYNGHPEFAHLPVDLS
Mflv_1720|M.gilvum_PYR-GCK HHAVLYAVGAPSDRRLDIDGMELPGTATATDLVAWYNGHPEAADLRVDLH
MSMEG_5681|M.smegmatis_MC2_155 HHAVVYAVGAPNDRRLDIEGMDLPGTATATEVVAWINGHPDHTDLPVRLD
TH_1806|M.thermoresistible__bu HHAVLYAVGAPNDRRLDIDGMGLPGTGTATEVVAWYNGHPDFADLPVDLS
MAB_0930|M.abscessus_ATCC_1997 HHAVIYSVGASSDRRLDIPGIELPGNATATQVVAWINAHPDYADFRVDLD
****:*:***..**** * *: .*..***::*** *.**: : * *
Mb0910|M.bovis_AF2122/97 HERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVV
Rv0886|M.tuberculosis_H37Rv HERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVV
MMAR_4646|M.marinum_M HERAVIIGNGNVALDVARMLTANPDDLARTDIADPALRALRNSAVREVVI
MUL_0264|M.ulcerans_Agy99 HERAVITGNGNVALDVARMLTANPDDLARTDIADPALRALRNSAVREVVI
MLBr_02134|M.leprae_Br4923 HERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVV
MAV_1015|M.avium_104 HERVVIIGNGNVALDVARVLTADPDDLARTDIADHALAALRGSAVREVVI
Mvan_5031|M.vanbaalenii_PYR-1 GDRVVIIGNGNVALDVARILTAEPDVLARTDIADHALAVLRDSRVREVVI
Mflv_1720|M.gilvum_PYR-GCK TERVVVIGNGNVALDVARILTTDPDALARTDIADHALARLRDSQVREVVV
MSMEG_5681|M.smegmatis_MC2_155 HERVVIVGNGNVALDVARVLTSDPDALARTDISDHALAALRSSAVQEVVI
TH_1806|M.thermoresistible__bu GDRVVIVGNGNVALDVARILTADPDELARTDIADHALAALRSSRVREVVI
MAB_0930|M.abscessus_ATCC_1997 HERAVVIGNGNVALDVARVLTGDVERLARTDISDTALTALRSSKLREVVI
:*.*: ***********:*: : . ** ***:: ** * .* ::***:
Mb0910|M.bovis_AF2122/97 AARRGPAHSAFTLPELIGLTAG--ADVVLDPGDHQRVLDDLAIVADPLTR
Rv0886|M.tuberculosis_H37Rv AARRGPAHSAFTLPELIGLTAG--ADVVLDPGDHQRVLDDLAIVADPLTR
MMAR_4646|M.marinum_M AARRGPAHSAFTLPELIGLTGC--AEVVLDAADRQRVLDDLATVSDQLTK
MUL_0264|M.ulcerans_Agy99 AARRGPAHSAFTLPELIGLTGC--AEVVLDAADRQRVLDDLATVSDQLTK
MLBr_02134|M.leprae_Br4923 AARRGPAHSAFTLPELIGLKAT--SEVVLDAGDRKLVEGDFATVSDSLTR
MAV_1015|M.avium_104 AARRGPAQSAFTLPELIGLTGS--REVVLSAADRELVAADLANASDALTK
Mvan_5031|M.vanbaalenii_PYR-1 AARRGPAASSFTLPELIGLTST--CEVVLDPADHERVLTDLAAATDPLTR
Mflv_1720|M.gilvum_PYR-GCK AARRGPAAAAFTLPELIGLTSS--CDVVLDPADHDSVLAELAEATDPLTR
MSMEG_5681|M.smegmatis_MC2_155 AARRGPAASAFTLPELIGLTST--CDVVLDSADHDLVLRDLAQETDPLTR
TH_1806|M.thermoresistible__bu AARRGPADSAFTLPELIGLTAT--ADVVLDARDHELVDRDLARTTDSLTR
MAB_0930|M.abscessus_ATCC_1997 VGRRGPEHSAFTLPELLGLVGLPDMTVVVDQETADLVDQALQTHLEPLTR
..**** ::******:** . **:. . * : : **:
Mb0910|M.bovis_AF2122/97 NKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQ-----RRAGGVQ
Rv0886|M.tuberculosis_H37Rv NKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQ-----RRAGGVQ
MMAR_4646|M.marinum_M RKLEILATLGEGS-AASGP---RIRLAYQLTPRSVRGE-----QRVSGVE
MUL_0264|M.ulcerans_Agy99 RKLEILATLGEGS-AASGP---RIRLAYQLTPRSVRGE-----QRASGVE
MLBr_02134|M.leprae_Br4923 KKLEVLSSLVDSSKPTSRR---RIRLAYQLTPKRVLGN-----QRATGVE
MAV_1015|M.avium_104 AKLEVLSTLGDAAAPSERP---RIRLAYRLTPDRILGE-----QRVTGVQ
Mvan_5031|M.vanbaalenii_PYR-1 SKLEIMSKLGDATAPVTRP---RIRLAYRLTPRRVLGE-----ERATGVQ
Mflv_1720|M.gilvum_PYR-GCK NKLEILSTLGDTTAPVTRP---RIRLAYQLTPRRITGD-----ARAAGVE
MSMEG_5681|M.smegmatis_MC2_155 NKLEILAKLGDASAPITRP---RIRFAYQLTPRRVLGE-----NQVTAVE
TH_1806|M.thermoresistible__bu NKLEILAKLPDAAAPITRP---RIRFAYQLTPRAILRAGAPAADRAAGIE
MAB_0930|M.abscessus_ATCC_1997 QKLEVLSTCPREAREPGGK---TIRFAYNRTPARVLGE-----DRVEAIE
***:::. : **:**. ** : :. .::
Mb0910|M.bovis_AF2122/97 FSVTGTDELRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDP
Rv0886|M.tuberculosis_H37Rv FSVTGTDELRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDP
MMAR_4646|M.marinum_M FSVTGTDEMRTLDAGLVLTSIGYRGKKIGDLPFDDNAAVVPNDGGRVVDP
MUL_0264|M.ulcerans_Agy99 FSVTGTDEMRTLDAGLVLTSIGYRGTKIGDLPFDDNAAVVRNDGGRVVDP
MLBr_02134|M.leprae_Br4923 FSVTGTEESRRFDAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDP
MAV_1015|M.avium_104 FTLTGTDETHCLPTGLVLTSIGYRGKPIRDLPYDEAAAVVPNDGGRVVDP
Mvan_5031|M.vanbaalenii_PYR-1 FDVTGTGETCELTAGLVLTSIGYRGKPIRGLPFDEAAAVVPNAGGRVVDP
Mflv_1720|M.gilvum_PYR-GCK FTVTGGDEVVEISAGLVLTSIGYRGTPIRGLPFDADAAVVPNDGGRVIA-
MSMEG_5681|M.smegmatis_MC2_155 FGVTGTDEVRTLDAGLLLTSIGYRGKAIADLPFDEDASVVPNDGGRVIDP
TH_1806|M.thermoresistible__bu FVRTGTDEVCRLDAGLVLTSIGYRGRPIRDLPFDDTAAVVPNDGGRVVDP
MAB_0930|M.abscessus_ATCC_1997 FQHGDTTDT--IKAGLFLTSIGYRGVPMPDVPFDSQRGTIPNEQGRVKDS
* . : : :**.***:**** : .:*:* . : * ***
Mb0910|M.bovis_AF2122/97 GTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALVADFNDGRLTDPV
Rv0886|M.tuberculosis_H37Rv GTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALVADFNDGRLTDPV
MMAR_4646|M.marinum_M VRGAPVPGVYVAGWIKRGPSGFIGTNKSCSLQTVAALVADFNAGKLGDPV
MUL_0264|M.ulcerans_Agy99 VRGAPVPGVYVAGWIKRGPSGFIGTNKSCSLQTVAALVADFNAGKLGDPV
MLBr_02134|M.leprae_Br4923 SRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADFNAGWLTDPV
MAV_1015|M.avium_104 ASRRPVPGAYVAGWIKRGPSGFIGTNKSCSLQTVQALVADFNAGELADPA
Mvan_5031|M.vanbaalenii_PYR-1 ETGEPVRGSYVAGWIKRGPTGFIGTNKSCAAETVHHLAADYNAGLLADPS
Mflv_1720|M.gilvum_PYR-GCK -GADPVRGSYVAGWIKRGPTGFIGTNKSCAAETVHNLVADYNDGLLADPV
MSMEG_5681|M.smegmatis_MC2_155 ATGAPVPGAYVAGWIKRGPTGFIGTNKSCAAQTVHHLVDDYNAGALTDPP
TH_1806|M.thermoresistible__bu ATGRPVPGSYVAGWIKRGPTGFIGTNKSCAAETVHKLVDDYNAGLLTEPI
MAB_0930|M.abscessus_ATCC_1997 STGQAHPGTYVAGWIKRGPTGFIGTNKSCSQQTVTSLVEDYNNGLLADPP
. * **********:******* *: :** :. *:* * * :*
Mb0910|M.bovis_AF2122/97 ATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEM
Rv0886|M.tuberculosis_H37Rv ATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEM
MMAR_4646|M.marinum_M CKPAALAKLVHTREPDVIDSAGWFAIDAAEIARGNGEGRPRNKFTDVADM
MUL_0264|M.ulcerans_Agy99 CKPAALAKLVHTREPDVIDSAGWFAIDAAEIARGNAEGRPRNKFTDVADM
MLBr_02134|M.leprae_Br4923 AEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADM
MAV_1015|M.avium_104 AKPEALTALVRARRPDAIDAAGWRAIDAAEIARGSADGRPRNKFTDIGDM
Mvan_5031|M.vanbaalenii_PYR-1 HKASALDRFVRGRQPAVIDACGWRAIDAAEVARGAGL-RPRDKFTTVAEM
Mflv_1720|M.gilvum_PYR-GCK HRGAALEHFVRGRRPAVIGTAGWKAIDEAEIARGAGV-RPREKFTSVAEM
MSMEG_5681|M.smegmatis_MC2_155 RKPSALDKLVRARQPDVVDAAGWRAIDAAEIARGGDD-RPRDKFTTVPEM
TH_1806|M.thermoresistible__bu HRPSALDKLVRSRRPDLVTAAGWRAIDAAEIDRGGQE-RPRVKFTGTDQM
MAB_0930|M.abscessus_ATCC_1997 QRLSGLSKVIQRRQPTIIGHDGWLAIDRAEIARGKGAGRPRDKFVSVPEM
* .:: *.* : ** *** **: :* * * **. :*
Mb0910|M.bovis_AF2122/97 LAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL--
Rv0886|M.tuberculosis_H37Rv LAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL--
MMAR_4646|M.marinum_M LGAAASGA--PVRS-----SRGLLAGILGR-----
MUL_0264|M.ulcerans_Agy99 LGAAASGA--PVRP-----SRGLLAAILGR-----
MLBr_02134|M.leprae_Br4923 LAVAAGAP--PLR------LRALS-----------
MAV_1015|M.avium_104 LAAAAAAEPAPPPR------RRLLARLVPSGRG--
Mvan_5031|M.vanbaalenii_PYR-1 ENVAAAAAAPPMS-------KRLLEALRR------
Mflv_1720|M.gilvum_PYR-GCK VEVAANAPAPPIH-------RRVLAALRR------
MSMEG_5681|M.smegmatis_MC2_155 LAVAVTAPKPSVR-------QRLTAGLLG------
TH_1806|M.thermoresistible__bu LAVARTAPAPPLR-------QRLLAALRQPLTGVV
MAB_0930|M.abscessus_ATCC_1997 LRVAADAPQPPLWR------KAIRGSALEDLLR--
.* . . : :