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VVCHGRGVQTGGQERSDPGIGSCLEEFDEYLALERGRSEHTRRAYLGDVRALFDFLAERRPGTGLRGLTL PVLRSWLAAQATAGAARSTLARRTSAVKTFTAWAVRRGLMTEDPAARLQVPKARRTLPSVLRQDQAREAM DAAKSGAQQGDPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTARRLLRVLGKGNKQRTVPYGDPAHAA LTAWLSDGRPALVTAGSGAALLLGARGGRLDPRQARTVVHQTMAAVSGAPDIGPHGLRHSAATHLLEGGA DLRVVQELLGHSSLATTQLYTHVTVARLRAVHDQAHPRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2207 | xerC | - | 100% (319) | site-specific tyrosine recombinase XerC |
| M. vanbaalenii PYR-1 | Mvan_3281 | xerD | 1e-54 | 41.81% (299) | site-specific tyrosine recombinase XerD |
| M. vanbaalenii PYR-1 | Mvan_5497 | - | 5e-25 | 31.45% (318) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 1e-134 | 81.33% (300) | site-specific tyrosine recombinase XerC |
| M. gilvum PYR-GCK | Mflv_4135 | xerC | 1e-149 | 88.18% (296) | site-specific tyrosine recombinase XerC |
| M. tuberculosis H37Rv | Rv2894c | xerC | 1e-134 | 81.33% (300) | site-specific tyrosine recombinase XerC |
| M. leprae Br4923 | MLBr_01600 | xerC | 1e-127 | 79.05% (296) | site-specific tyrosine recombinase XerC |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 1e-130 | 77.15% (302) | site-specific tyrosine recombinase XerC |
| M. marinum M | MMAR_1817 | xerC | 1e-136 | 83.78% (296) | integrase/recombinase XerC |
| M. avium 104 | MAV_3746 | xerC | 1e-135 | 82.77% (296) | site-specific tyrosine recombinase XerC |
| M. smegmatis MC2 155 | MSMEG_2515 | xerC | 1e-134 | 78.19% (298) | site-specific tyrosine recombinase XerC |
| M. thermoresistible (build 8) | TH_0846 | xerC | 1e-137 | 80.67% (300) | PROBABLE INTEGRASE/RECOMBINASE XERC |
| M. ulcerans Agy99 | MUL_2065 | xerC | 1e-134 | 83.11% (296) | site-specific tyrosine recombinase XerC |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2207|M.vanbaalenii_PYR-1 MVCHGRGVQTGGQERSDPGIGSCLEEFDEYLALERGRSEHTRRAYLGDVR
Mflv_4135|M.gilvum_PYR-GCK -------------------MDTVLEEFDRYLELERGRSEHTRRAYLGDLR
MMAR_1817|M.marinum_M ---------------MPDNSEAILEEFDEYLALQCGRSAHTRRAYLGDLR
MUL_2065|M.ulcerans_Agy99 ---------------MPDNSEAILEEFDEYLALQCGRSAHTRRAYLGDLR
MLBr_01600|M.leprae_Br4923 --------------------MAILDEFDEHLALRCGRSEHTRRAYLGDLR
Mb2918c|M.bovis_AF2122/97 -------------------MQAILDEFDEYLALQCGRSVHTRRAYLGDLR
Rv2894c|M.tuberculosis_H37Rv -------------------MQAILDEFDEYLALQCGRSVHTRRAYLGDLR
MAV_3746|M.avium_104 ----------------MPDSEPILEEFDEYLALQCGRSAHTRRAYLGDLR
MSMEG_2515|M.smegmatis_MC2_155 -------------------MESVLDQFDAYLGLERGHSDHTRRAYRGDLT
TH_0846|M.thermoresistible__bu -----------------MSVDTVLDEFADYLALQRGRSPHTCRAYLGDLR
MAB_3204c|M.abscessus_ATCC_199 ---------------MTPQLAAILDEFAEHLALERGRSVHTQRAYRGDLT
. *::* :* *. *:* ** *** **:
Mvan_2207|M.vanbaalenii_PYR-1 ALFDFLAERRPGTGLRGLTLPVLRSWLAAQATAGAARSTLARRTSAVKTF
Mflv_4135|M.gilvum_PYR-GCK SLFAFLDERSPGTGLGGLTLPMLRSWLAAHAAAGTARSTLARRTSSVKTF
MMAR_1817|M.marinum_M SLLDYLAGR--GADLRALSLPVLRSWLATAAGAGAARTTLARRTSAVKAF
MUL_2065|M.ulcerans_Agy99 SLLDYLAGR--GADLRALSLPVLRSWLATAAGAGAARTTLARRTSAVKAF
MLBr_01600|M.leprae_Br4923 SLLTHLEGR--GSRLDQLSLPVLRSWLATAAGAGAARTTLARRISAVKAF
Mb2918c|M.bovis_AF2122/97 SLFAFLADR--GSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAF
Rv2894c|M.tuberculosis_H37Rv SLFAFLADR--GSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAF
MAV_3746|M.avium_104 SLLAFAGER--GTGLDGLSLPLLRSWLSAAAAGGVARTTLARRTSAVKAF
MSMEG_2515|M.smegmatis_MC2_155 ALFDFVEQRTGERSLARVSLPLLRSWLAEQSASGAARTTLARRTSSVKTF
TH_0846|M.thermoresistible__bu SLFDFVEQRSPGSGLGGLSLPVLRAWLAAQAADGSARTTLARRTSAVKTF
MAB_3204c|M.abscessus_ATCC_199 LLFDHLSASNPEATLADLSLPVLRSWLGAQARQGAARSTVARRTSAVKIF
*: . * ::*.:**:**. : * **:*:*** *:** *
Mvan_2207|M.vanbaalenii_PYR-1 TAWAVRRGLMTEDPAARLQVPKARRTLPSVLRQDQAREAMDAAKSGAQQG
Mflv_4135|M.gilvum_PYR-GCK TAWAVRRGLIGDDPASRLQVPKARRTLPSVLRQDQARDALEAAESGAQQG
MMAR_1817|M.marinum_M TAWAVRRGLLATDPAARLQVPKAHRTLPAVLRQDQALAAMTAAKSGAQQG
MUL_2065|M.ulcerans_Agy99 TAWAVRRGLLATDPAARLQVPKAHRTLPAVLRQDQALAAMTAAKSSAQQG
MLBr_01600|M.leprae_Br4923 TAWAKWRGQLAADPAARLQVPRAYRTLPAVLRQDQALQIMAAAKSGAEQG
Mb2918c|M.bovis_AF2122/97 TAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQG
Rv2894c|M.tuberculosis_H37Rv TAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQG
MAV_3746|M.avium_104 TAWAVRRGLLTADPAARLQVPKTHRTLPAVLRQDQALGAMAAAKNGAAQG
MSMEG_2515|M.smegmatis_MC2_155 CAWALRRGLIGVDPAARLQVPKARRTLPAVLRRDQALDALDAVNSGAQEG
TH_0846|M.thermoresistible__bu TAWAVRQGLLSTDPALRLQVPKARRTLPAVLRRDQALAAMAAADSGAQQK
MAB_3204c|M.abscessus_ATCC_199 TAWATRRGLLPTDPAIRLQQPKSRRTLPAVLRQDQAAAAMEAAHSGAEQD
*** :* : *** *** *:: ****:***:*** : *....* :
Mvan_2207|M.vanbaalenii_PYR-1 DPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTARRLLRVLGKGNKQRT
Mflv_4135|M.gilvum_PYR-GCK DPLAVRDRLVVEMLYATGIRVSELCGLDVDDVDTSRRLLRVLGKGNKQRT
MMAR_1817|M.marinum_M DPLALRDRLIVELLYATGIRVSELCGLDIDDVDTGHRLVRVLGKGNKQRT
MUL_2065|M.ulcerans_Agy99 DPLALRDRLIVELLYATGIRVSELRGLDIDDVDTGHRLVRVLGKGNKQRT
MLBr_01600|M.leprae_Br4923 DPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTRHRLVRVLGKGNKQRT
Mb2918c|M.bovis_AF2122/97 DPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRT
Rv2894c|M.tuberculosis_H37Rv DPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRT
MAV_3746|M.avium_104 DPIALRDRLIVEMLYATGIRVSELCGLDIDDVDTGRRLVRVLGKGNKQRS
MSMEG_2515|M.smegmatis_MC2_155 DPIALRDRLIVELLYATGIRVSELCGLDIDDIDTSRRVVRVLGKGNKQRT
TH_0846|M.thermoresistible__bu DPIALRDRLIVEMLYATGIRVSELCGLDIDDVDTDRHLARVLGKGGRQRT
MAB_3204c|M.abscessus_ATCC_199 DPMALRDRLIVEMLYATGIRVSELCGLDIDDIDRPRKVLRVLGKGDKERT
**:*:****:**:*********** ***:**:* ::: ******.::*:
Mvan_2207|M.vanbaalenii_PYR-1 VPYGDPAHAALTAWLSDGRPALVTAGSGAALLLGARGGRLDPRQARTVVH
Mflv_4135|M.gilvum_PYR-GCK VPYGEPAHAALTAWLHEGRPALATADSGPALLLGARGKRLDPRQARTVVH
MMAR_1817|M.marinum_M APFGQPAAEALQAWLADGRPALATAESGPALLLGARGRRLDVRQARTVVH
MUL_2065|M.ulcerans_Agy99 APFGQPAAEALQAWLADGRPALATAESGPALLLGARGRRLDVRQARTVVH
MLBr_01600|M.leprae_Br4923 APFGVPAADALRGWLDDGRPALVTVESGPALLLGSRGRRLDVRQARTVVH
Mb2918c|M.bovis_AF2122/97 VPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVH
Rv2894c|M.tuberculosis_H37Rv VPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVH
MAV_3746|M.avium_104 VPFGAPAGEALHAWLADGRPALANAESGPALLLGARGRRLDVRQARTVVH
MSMEG_2515|M.smegmatis_MC2_155 VPFGEPAHAALTAWLTEGRPQLSIPESGPALLLGARGRRLDPRQARTVVH
TH_0846|M.thermoresistible__bu VPFGEPARGALTDWLTDGRPALATAESGPALLLGVRGRRLDPRQARTVVH
MAB_3204c|M.abscessus_ATCC_199 VPFGDPAADALSAWLDRGRPHLAVPASGAALLLGARGRRVDPRQVRTVVH
.*:* ** ** ** ** * ** ***** ** *:* **.**.**
Mvan_2207|M.vanbaalenii_PYR-1 QTMAAVSGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Mflv_4135|M.gilvum_PYR-GCK QTVSAVGGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MMAR_1817|M.marinum_M QTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MUL_2065|M.ulcerans_Agy99 QTIAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MLBr_01600|M.leprae_Br4923 QTVAVVAGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Mb2918c|M.bovis_AF2122/97 QTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Rv2894c|M.tuberculosis_H37Rv QTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MAV_3746|M.avium_104 QTIAAVSGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MSMEG_2515|M.smegmatis_MC2_155 QTVSAVNGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQLY
TH_0846|M.thermoresistible__bu QTVAAVAGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQLY
MAB_3204c|M.abscessus_ATCC_199 QTMSAVPGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSTLATTQLY
**::.* ****:*********************:*******::*******
Mvan_2207|M.vanbaalenii_PYR-1 THVTVARLRAVHDQAHPRA
Mflv_4135|M.gilvum_PYR-GCK THVTVARLRAVHDQAHPRA
MMAR_1817|M.marinum_M THVAVSRLRAVHDQAHPRA
MUL_2065|M.ulcerans_Agy99 THVAVSRLRAVHDQAHPRA
MLBr_01600|M.leprae_Br4923 THVAVSRLRVVHDQAHPRA
Mb2918c|M.bovis_AF2122/97 THVAVARLRAVHERAHPRA
Rv2894c|M.tuberculosis_H37Rv THVAVARLRAVHERAHPRA
MAV_3746|M.avium_104 THVAVSRLRAVHDQAHPRA
MSMEG_2515|M.smegmatis_MC2_155 THVTVERLRAVHDQAHPRA
TH_0846|M.thermoresistible__bu THVTVERLRAVHDQAHPRA
MAB_3204c|M.abscessus_ATCC_199 THVTVARLRAVHDQAHPRA
***:* ***.**::*****