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MESVLDQFDAYLGLERGHSDHTRRAYRGDLTALFDFVEQRTGERSLARVSLPLLRSWLAEQSASGAARTT LARRTSSVKTFCAWALRRGLIGVDPAARLQVPKARRTLPAVLRRDQALDALDAVNSGAQEGDPIALRDRL IVELLYATGIRVSELCGLDIDDIDTSRRVVRVLGKGNKQRTVPFGEPAHAALTAWLTEGRPQLSIPESGP ALLLGARGRRLDPRQARTVVHQTVSAVNGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQL YTHVTVERLRAVHDQAHPRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2515 | xerC | - | 100% (300) | site-specific tyrosine recombinase XerC |
| M. smegmatis MC2 155 | MSMEG_3744 | xerD | 5e-57 | 42.31% (312) | site-specific tyrosine recombinase XerD |
| M. smegmatis MC2 155 | MSMEG_4155 | - | 6e-13 | 30.18% (222) | transposase A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 1e-124 | 74.67% (300) | site-specific tyrosine recombinase XerC |
| M. gilvum PYR-GCK | Mflv_4135 | xerC | 1e-139 | 79.33% (300) | site-specific tyrosine recombinase XerC |
| M. tuberculosis H37Rv | Rv2894c | xerC | 1e-124 | 74.67% (300) | site-specific tyrosine recombinase XerC |
| M. leprae Br4923 | MLBr_01600 | xerC | 1e-121 | 73.15% (298) | site-specific tyrosine recombinase XerC |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 1e-126 | 73.67% (300) | site-specific tyrosine recombinase XerC |
| M. marinum M | MMAR_1817 | xerC | 1e-129 | 76.25% (299) | integrase/recombinase XerC |
| M. avium 104 | MAV_3746 | xerC | 1e-126 | 75.67% (300) | site-specific tyrosine recombinase XerC |
| M. thermoresistible (build 8) | TH_0846 | xerC | 1e-135 | 79.33% (300) | PROBABLE INTEGRASE/RECOMBINASE XERC |
| M. ulcerans Agy99 | MUL_2065 | xerC | 1e-127 | 75.25% (299) | site-specific tyrosine recombinase XerC |
| M. vanbaalenii PYR-1 | Mvan_2207 | xerC | 1e-134 | 78.19% (298) | site-specific tyrosine recombinase XerC |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2515|M.smegmatis_MC2_155 -------------------MESVLDQFDAYLGLERGHSDHTRRAYRGDLT
TH_0846|M.thermoresistible__bu -----------------MSVDTVLDEFADYLALQRGRSPHTCRAYLGDLR
MMAR_1817|M.marinum_M ---------------MPDNSEAILEEFDEYLALQCGRSAHTRRAYLGDLR
MUL_2065|M.ulcerans_Agy99 ---------------MPDNSEAILEEFDEYLALQCGRSAHTRRAYLGDLR
MLBr_01600|M.leprae_Br4923 --------------------MAILDEFDEHLALRCGRSEHTRRAYLGDLR
Mb2918c|M.bovis_AF2122/97 -------------------MQAILDEFDEYLALQCGRSVHTRRAYLGDLR
Rv2894c|M.tuberculosis_H37Rv -------------------MQAILDEFDEYLALQCGRSVHTRRAYLGDLR
MAV_3746|M.avium_104 ----------------MPDSEPILEEFDEYLALQCGRSAHTRRAYLGDLR
Mflv_4135|M.gilvum_PYR-GCK -------------------MDTVLEEFDRYLELERGRSEHTRRAYLGDLR
Mvan_2207|M.vanbaalenii_PYR-1 MVCHGRGVQTGGQERSDPGIGSCLEEFDEYLALERGRSEHTRRAYLGDVR
MAB_3204c|M.abscessus_ATCC_199 ---------------MTPQLAAILDEFAEHLALERGRSVHTQRAYRGDLT
. *::* :* *. *:* ** *** **:
MSMEG_2515|M.smegmatis_MC2_155 ALFDFVEQRTGERSLARVSLPLLRSWLAEQSASGAARTTLARRTSSVKTF
TH_0846|M.thermoresistible__bu SLFDFVEQRSPGSGLGGLSLPVLRAWLAAQAADGSARTTLARRTSAVKTF
MMAR_1817|M.marinum_M SLLDYLAGR--GADLRALSLPVLRSWLATAAGAGAARTTLARRTSAVKAF
MUL_2065|M.ulcerans_Agy99 SLLDYLAGR--GADLRALSLPVLRSWLATAAGAGAARTTLARRTSAVKAF
MLBr_01600|M.leprae_Br4923 SLLTHLEGR--GSRLDQLSLPVLRSWLATAAGAGAARTTLARRISAVKAF
Mb2918c|M.bovis_AF2122/97 SLFAFLADR--GSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAF
Rv2894c|M.tuberculosis_H37Rv SLFAFLADR--GSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAF
MAV_3746|M.avium_104 SLLAFAGER--GTGLDGLSLPLLRSWLSAAAAGGVARTTLARRTSAVKAF
Mflv_4135|M.gilvum_PYR-GCK SLFAFLDERSPGTGLGGLTLPMLRSWLAAHAAAGTARSTLARRTSSVKTF
Mvan_2207|M.vanbaalenii_PYR-1 ALFDFLAERRPGTGLRGLTLPVLRSWLAAQATAGAARSTLARRTSAVKTF
MAB_3204c|M.abscessus_ATCC_199 LLFDHLSASNPEATLADLSLPVLRSWLGAQARQGAARSTVARRTSAVKIF
*: . * ::*.:**:**. : * **:*:*** *:** *
MSMEG_2515|M.smegmatis_MC2_155 CAWALRRGLIGVDPAARLQVPKARRTLPAVLRRDQALDALDAVNSGAQEG
TH_0846|M.thermoresistible__bu TAWAVRQGLLSTDPALRLQVPKARRTLPAVLRRDQALAAMAAADSGAQQK
MMAR_1817|M.marinum_M TAWAVRRGLLATDPAARLQVPKAHRTLPAVLRQDQALAAMTAAKSGAQQG
MUL_2065|M.ulcerans_Agy99 TAWAVRRGLLATDPAARLQVPKAHRTLPAVLRQDQALAAMTAAKSSAQQG
MLBr_01600|M.leprae_Br4923 TAWAKWRGQLAADPAARLQVPRAYRTLPAVLRQDQALQIMAAAKSGAEQG
Mb2918c|M.bovis_AF2122/97 TAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQG
Rv2894c|M.tuberculosis_H37Rv TAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQG
MAV_3746|M.avium_104 TAWAVRRGLLTADPAARLQVPKTHRTLPAVLRQDQALGAMAAAKNGAAQG
Mflv_4135|M.gilvum_PYR-GCK TAWAVRRGLIGDDPASRLQVPKARRTLPSVLRQDQARDALEAAESGAQQG
Mvan_2207|M.vanbaalenii_PYR-1 TAWAVRRGLMTEDPAARLQVPKARRTLPSVLRQDQAREAMDAAKSGAQQG
MAB_3204c|M.abscessus_ATCC_199 TAWATRRGLLPTDPAIRLQQPKSRRTLPAVLRQDQAAAAMEAAHSGAEQD
*** :* : *** *** *:: ****:***:*** : *....* :
MSMEG_2515|M.smegmatis_MC2_155 DPIALRDRLIVELLYATGIRVSELCGLDIDDIDTSRRVVRVLGKGNKQRT
TH_0846|M.thermoresistible__bu DPIALRDRLIVEMLYATGIRVSELCGLDIDDVDTDRHLARVLGKGGRQRT
MMAR_1817|M.marinum_M DPLALRDRLIVELLYATGIRVSELCGLDIDDVDTGHRLVRVLGKGNKQRT
MUL_2065|M.ulcerans_Agy99 DPLALRDRLIVELLYATGIRVSELRGLDIDDVDTGHRLVRVLGKGNKQRT
MLBr_01600|M.leprae_Br4923 DPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTRHRLVRVLGKGNKQRT
Mb2918c|M.bovis_AF2122/97 DPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRT
Rv2894c|M.tuberculosis_H37Rv DPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRT
MAV_3746|M.avium_104 DPIALRDRLIVEMLYATGIRVSELCGLDIDDVDTGRRLVRVLGKGNKQRS
Mflv_4135|M.gilvum_PYR-GCK DPLAVRDRLVVEMLYATGIRVSELCGLDVDDVDTSRRLLRVLGKGNKQRT
Mvan_2207|M.vanbaalenii_PYR-1 DPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTARRLLRVLGKGNKQRT
MAB_3204c|M.abscessus_ATCC_199 DPMALRDRLIVEMLYATGIRVSELCGLDIDDIDRPRKVLRVLGKGDKERT
**:*:****:**:*********** ***:**:* ::: ******.::*:
MSMEG_2515|M.smegmatis_MC2_155 VPFGEPAHAALTAWLTEGRPQLSIPESGPALLLGARGRRLDPRQARTVVH
TH_0846|M.thermoresistible__bu VPFGEPARGALTDWLTDGRPALATAESGPALLLGVRGRRLDPRQARTVVH
MMAR_1817|M.marinum_M APFGQPAAEALQAWLADGRPALATAESGPALLLGARGRRLDVRQARTVVH
MUL_2065|M.ulcerans_Agy99 APFGQPAAEALQAWLADGRPALATAESGPALLLGARGRRLDVRQARTVVH
MLBr_01600|M.leprae_Br4923 APFGVPAADALRGWLDDGRPALVTVESGPALLLGSRGRRLDVRQARTVVH
Mb2918c|M.bovis_AF2122/97 VPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVH
Rv2894c|M.tuberculosis_H37Rv VPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVH
MAV_3746|M.avium_104 VPFGAPAGEALHAWLADGRPALANAESGPALLLGARGRRLDVRQARTVVH
Mflv_4135|M.gilvum_PYR-GCK VPYGEPAHAALTAWLHEGRPALATADSGPALLLGARGKRLDPRQARTVVH
Mvan_2207|M.vanbaalenii_PYR-1 VPYGDPAHAALTAWLSDGRPALVTAGSGAALLLGARGGRLDPRQARTVVH
MAB_3204c|M.abscessus_ATCC_199 VPFGDPAADALSAWLDRGRPHLAVPASGAALLLGARGRRVDPRQVRTVVH
.*:* ** ** ** ** * ** ***** ** *:* **.**.**
MSMEG_2515|M.smegmatis_MC2_155 QTVSAVNGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQLY
TH_0846|M.thermoresistible__bu QTVAAVAGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQLY
MMAR_1817|M.marinum_M QTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MUL_2065|M.ulcerans_Agy99 QTIAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MLBr_01600|M.leprae_Br4923 QTVAVVAGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Mb2918c|M.bovis_AF2122/97 QTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Rv2894c|M.tuberculosis_H37Rv QTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MAV_3746|M.avium_104 QTIAAVSGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Mflv_4135|M.gilvum_PYR-GCK QTVSAVGGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
Mvan_2207|M.vanbaalenii_PYR-1 QTMAAVSGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLY
MAB_3204c|M.abscessus_ATCC_199 QTMSAVPGAPDIGPHGLRHSAATHLLEGGADLRVVQELLGHSTLATTQLY
**::.* ****:*********************:*******::*******
MSMEG_2515|M.smegmatis_MC2_155 THVTVERLRAVHDQAHPRA
TH_0846|M.thermoresistible__bu THVTVERLRAVHDQAHPRA
MMAR_1817|M.marinum_M THVAVSRLRAVHDQAHPRA
MUL_2065|M.ulcerans_Agy99 THVAVSRLRAVHDQAHPRA
MLBr_01600|M.leprae_Br4923 THVAVSRLRVVHDQAHPRA
Mb2918c|M.bovis_AF2122/97 THVAVARLRAVHERAHPRA
Rv2894c|M.tuberculosis_H37Rv THVAVARLRAVHERAHPRA
MAV_3746|M.avium_104 THVAVSRLRAVHDQAHPRA
Mflv_4135|M.gilvum_PYR-GCK THVTVARLRAVHDQAHPRA
Mvan_2207|M.vanbaalenii_PYR-1 THVTVARLRAVHDQAHPRA
MAB_3204c|M.abscessus_ATCC_199 THVTVARLRAVHDQAHPRA
***:* ***.**::*****