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M. avium 104 MAV_0598 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 581867 - 582811
length: 314

KFALDEQQRDFAASIDAALGAADLPAAVRAWAVGDTAPGRKVWEQLANLGVTALAVPEKFDGIEAEPIDL
VVAIERLGRWCVPGPVVESIAVAPVLLAGDEHAERCAALASGELIATVALPPQVPRAVDAEEAGLVLLAD
QDGVAEAAAGRQHASVDPSRRLYDVEPTGDRWQADVGRGYEFGALATAAQLVGAAEALRDAAVDYAKQRT
QFGRVIGSYQAIKHKLADVHIAIELARPLVYGAALTLQPRDVSAAKAAASDAALLAARSALQTHGAIGFT
QEHDLSLLLLRVQAVRSAWGPPQVHRRRVLEAL*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_0598 - - 100% (314) putative acyl-CoA dehydrogenase
M. avium 104 MAV_0597 - 2e-33 30.65% (310) putative acyl-CoA dehydrogenase
M. avium 104 MAV_0934 - 8e-29 28.66% (328) putative acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3593 fadE32 1e-136 78.55% (317) acyl-CoA dehydrogenase FADE32
M. gilvum PYR-GCK Mflv_1478 - 1e-128 74.38% (320) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3563 fadE32 1e-135 78.23% (317) acyl-CoA dehydrogenase FADE32
M. leprae Br4923 MLBr_00737 fadE25 8e-16 25.61% (371) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0594c - 1e-113 66.98% (321) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5052 fadE32 1e-142 82.80% (314) acyl-CoA dehydrogenase FadE32
M. smegmatis MC2 155 MSMEG_6015 - 1e-131 76.25% (320) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2067 fadE32 1e-129 72.92% (325) PROBABLE ACYL-CoA DEHYDROGENASE FADE32
M. ulcerans Agy99 MUL_4128 fadE32 1e-140 82.17% (314) acyl-CoA dehydrogenase FadE32
M. vanbaalenii PYR-1 Mvan_5288 - 1e-130 75.62% (320) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1478|M.gilvum_PYR-GCK          ----------MNFEIDDQQRDFAASIDAALGAADLPAAVRAWGEGDTAPG
Mvan_5288|M.vanbaalenii_PYR-1       ----------MNFEIDEQQRDFAASIDAALGAADVPAAVRAWGEGDTAPG
MSMEG_6015|M.smegmatis_MC2_155      ----------MNFETDEQQRDFAASIDAALGASDVPAAVRAWGEGDTAPG
TH_2067|M.thermoresistible__bu      ----------VNFELDEQQRDFAASIDAALSAADVPAAVRAWAEGDASPG
MMAR_5052|M.marinum_M               ----------MEFALDEQQRDFAASIDAALAAADLPAAVRAWSAGDVAPG
MUL_4128|M.ulcerans_Agy99           ----------MEFALDEQQRDFAASIDAALAAADLPAAVRAWSAGDVAPG
Mb3593|M.bovis_AF2122/97            --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
Rv3563|M.tuberculosis_H37Rv         --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
MAV_0598|M.avium_104                ----------MKFALDEQQRDFAASIDAALGAADLPAAVRAWAVGDTAPG
MAB_0594c|M.abscessus_ATCC_199      ----------MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPG
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP--
                                                *    ::.:: *:* *       * .. .   .     

Mflv_1478|M.gilvum_PYR-GCK          RKVWSQLTDLGVTALMVPEKFDGIEAHPVDLVVALERLGRWNVPG---PV
Mvan_5288|M.vanbaalenii_PYR-1       RKVWSQLADLGVTALMVPEKFDGIEAHPVDLVVALERLGRWNVPG---PV
MSMEG_6015|M.smegmatis_MC2_155      RKVWAQLTDLGVTALLVPEKFDGIEAHPTDLVVALERLGYWGVPG---PV
TH_2067|M.thermoresistible__bu      RKIWFQLGELGVTALMVPERFDGIEAHPVDLVVALERLGRWCVPG---PV
MMAR_5052|M.marinum_M               HKVWEQLANLGVTALTVSEKFDGLGAHPIDLVVALERLGRWCVPG---PV
MUL_4128|M.ulcerans_Agy99           HKVWEQLANLGVTALTVSEKFDGLGAHPIDLVVALERLGRWCVPG---PV
Mb3593|M.bovis_AF2122/97            RKVWQQLANLGVTALGVAEKFDGLGASPVDLVVALERLGRWCVPG---PV
Rv3563|M.tuberculosis_H37Rv         RKVWQQLANLGVTALGVAEKFDGLGASPVDLVVALERLGRWCVPG---PV
MAV_0598|M.avium_104                RKVWEQLANLGVTALAVPEKFDGIEAEPIDLVVAIERLGRWCVPG---PV
MAB_0594c|M.abscessus_ATCC_199      LAVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGKWAVPG---PV
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPA
                                          *   *..*: *.*.:.*  * .    :.:* :.   ...   *.

Mflv_1478|M.gilvum_PYR-GCK          TESIAVAPILLG----DDDRVGALASGELIATVAAPPLVSRAVDADTAGL
Mvan_5288|M.vanbaalenii_PYR-1       AESVAVAPVLLA----DDDRSAALAAGELIATVAAPPLVPRAVNADTAGL
MSMEG_6015|M.smegmatis_MC2_155      TESIAVAPILLA----DDERCGALASGELIATVALPPQVPRAVDADTAGL
TH_2067|M.thermoresistible__bu      TESIAVAPVLLAGSAQEADRYPALAAGELIATVAAPPHTPRAVDADTAGL
MMAR_5052|M.marinum_M               AESIAVAPVLLA-DDD---RSAGLACGELIATVALPPHAPRAVDADTAGL
MUL_4128|M.ulcerans_Agy99           AESIAVAPVLLA-DDD---RSAGLACGELIATVALPPHAPRAVDADTAGL
Mb3593|M.bovis_AF2122/97            TESIAVAPILLA-HDDRAERSHGLASGELIATVAMPPRVPRAVDADTAGL
Rv3563|M.tuberculosis_H37Rv         TESIAVAPILLA-HDDQAERSHGLASGELIATVAMPPRVPRAVDADTAGL
MAV_0598|M.avium_104                VESIAVAPVLLA-GDEHAERCAALASGELIATVALPPQVPRAVDAEEAGL
MAB_0594c|M.abscessus_ATCC_199      VESVAVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGL
MLBr_00737|M.leprae_Br4923          VNKLGTMGLILR--GSEELKKQVLPSLAAEGAMASYALSEREAGSDAASM
                                    .:.:..  ::*            *..    .::*  .   *  .:: *.:

Mflv_1478|M.gilvum_PYR-GCK          ILLATEGA-------------------------VADAEMGT---------
Mvan_5288|M.vanbaalenii_PYR-1       ILLAEDGS-------------------------VSNASAGA---------
MSMEG_6015|M.smegmatis_MC2_155      ILLAQDGQ-------------------------VHDGSAGA---------
TH_2067|M.thermoresistible__bu      ILLAADGQ-------------------------VQDATAGA---------
MMAR_5052|M.marinum_M               VLVAGESG-------------------------VSEAAVAN---------
MUL_4128|M.ulcerans_Agy99           VLVAGESG-------------------------VCEAAVAD---------
Mb3593|M.bovis_AF2122/97            VLLAGDGS-------------------------VTEGTPGD---------
Rv3563|M.tuberculosis_H37Rv         VLLAGDGS-------------------------VTEGTPGD---------
MAV_0598|M.avium_104                VLLADQDG-------------------------VAEAAAGR---------
MAB_0594c|M.abscessus_ATCC_199      VLIADDIG-------------------------IREAQAGA---------
MLBr_00737|M.leprae_Br4923          RTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVH
                                       *                             : :   .          

Mflv_1478|M.gilvum_PYR-GCK          ---QHESVDPARKLFEVTAS-------------GEARAAD-------VER
Mvan_5288|M.vanbaalenii_PYR-1       ---EHESVDPSRKLFEVSAY-------------GDRKAAD-------VAR
MSMEG_6015|M.smegmatis_MC2_155      ---SHESVDPTRKLFDVAAS-------------GDARTAD-------TAT
TH_2067|M.thermoresistible__bu      ---AHESVDPSRKLFDVNGT-------------GVTHSAD-------TGR
MMAR_5052|M.marinum_M               ---CHESIDPSRRSYDVTAT-------------GATWQAD-------VKR
MUL_4128|M.ulcerans_Agy99           ---CHESIDPSRRSYDVTAT-------------GAAWQAD-------VKR
Mb3593|M.bovis_AF2122/97            ---CHRSVDPSRRLYEVAAS-------------GQAWRAPKDV----VAR
Rv3563|M.tuberculosis_H37Rv         ---CHRSVDPSRRLYEVAAS-------------GQAWRAPKDV----VAR
MAV_0598|M.avium_104                ---QHASVDPSRRLYDVEPT-------------GDRWQAD-------VGR
MAB_0594c|M.abscessus_ATCC_199      ---QHESIDATRRVFDVQPK-------------EAGISLD-------TSR
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
                                          *:.. .:   :                              .  

Mflv_1478|M.gilvum_PYR-GCK          AFEFGALATAAQLVGAAQAMLDASVEYAKQRSQFGTIIGTYQAIKHKLAD
Mvan_5288|M.vanbaalenii_PYR-1       AFEFGALATSALLVGAAQAMLDASVEYAKQRSQFGTVIGTYQAIKHKLAD
MSMEG_6015|M.smegmatis_MC2_155      AYEFGVLATAAQLVGAGQAMLDQAVEYAKQRTQFGRVIGSYQAIKHKLAD
TH_2067|M.thermoresistible__bu      AFEFGALGTAAQLIGAAQAMLDMSVDYAKQRSQFGNVIGSYQAIKHKLAD
MMAR_5052|M.marinum_M               AYEFGALATAAQLIGAAEALLDATVDYAKQRTQFGRVIGSYQAIKHKLAD
MUL_4128|M.ulcerans_Agy99           AYEFGALATAAQLIGAAEALLDATVDYAKQRTQFGRVIGSYQAIKHKLAD
Mb3593|M.bovis_AF2122/97            AYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLAD
Rv3563|M.tuberculosis_H37Rv         AYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLAD
MAV_0598|M.avium_104                GYEFGALATAAQLVGAAEALRDAAVDYAKQRTQFGRVIGSYQAIKHKLAD
MAB_0594c|M.abscessus_ATCC_199      AIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLAD
MLBr_00737|M.leprae_Br4923          TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
                                      :.     .*  :* .:.  : :: *:*:*.***  *.::*:::. ***

Mflv_1478|M.gilvum_PYR-GCK          VLIAVELARPLVYGAALSLAD----GSQDTARDVSAAKVAAADAALLAAR
Mvan_5288|M.vanbaalenii_PYR-1       VLIAVELARPLVYGAALSLAD----GSTDTGRDVSAAKVAAADAALLAAR
MSMEG_6015|M.smegmatis_MC2_155      VHIAVELARPLVYGAALSLAD----GSSDTARDVSAAKVAAADAALLAAR
TH_2067|M.thermoresistible__bu      VHIAVELARPLVYGAALSLAGRKEEASPDTARDVSAAKVAAGEAALLAAR
MMAR_5052|M.marinum_M               VHIAIELARPLVHGAALSLQP----------RDVSAAKVAAGDAALLAAR
MUL_4128|M.ulcerans_Agy99           VHIAIELARPLVHGAALSLQP----------RDVSAAKVAAGGAARLAAR
Mb3593|M.bovis_AF2122/97            VHIAIELACPLVYGAAVSLEP----------RDVSAAKAAASEAALLAAR
Rv3563|M.tuberculosis_H37Rv         VHIAIELACPLVYGAAVSLEP----------RDVSAAKAAASEAALLAAR
MAV_0598|M.avium_104                VHIAIELARPLVYGAALTLQP----------RDVSAAKAAASDAALLAAR
MAB_0594c|M.abscessus_ATCC_199      VHIALELARPLVYGAALSLAD----QSPTAARDASAAKVAAAKAAYLAAR
MLBr_00737|M.leprae_Br4923          MAMKVEAARLIVYAAAARAER----GEPDLGFISAASKCFASDIAMEVTT
                                    : : :* *  :*:.**                  :*:*  *.  *  .: 

Mflv_1478|M.gilvum_PYR-GCK          SSLQTHGAIGFTQEHDLSLLLLRVQALRPAWGDPTWHRHRVLEALTK
Mvan_5288|M.vanbaalenii_PYR-1       SSLQTHGAIGFTQEHDLSLLLLRVQALRPAWGDPTWHRRRVLEALTK
MSMEG_6015|M.smegmatis_MC2_155      SALQTHGAIGFTQEHDLSLLLLRVQALRPAWGDPALHRRRVLEGLS-
TH_2067|M.thermoresistible__bu      SSLQTHGAIGFTAEHDLSLWLLRVQALRTAWGDPTTHRRRVLEGIS-
MMAR_5052|M.marinum_M               SALQTHGAIGFTQEHDLSLWLLRVQALRSAWGTPEVHRRRVLEAL--
MUL_4128|M.ulcerans_Agy99           SALQTHGAIGFTQEHDLSLWLLRVQALRSAWGTPEVHRRRVLEAL--
Mb3593|M.bovis_AF2122/97            SALQTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL--
Rv3563|M.tuberculosis_H37Rv         WALQTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL--
MAV_0598|M.avium_104                SALQTHGAIGFTQEHDLSLLLLRVQAVRSAWGPPQVHRRRVLEAL--
MAB_0594c|M.abscessus_ATCC_199      SALQTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEAL--
MLBr_00737|M.leprae_Br4923          DAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
                                     ::* .*. *:* :. :.  :  .:      *    :*  : ..:

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_0598	-	-	100% (314)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_0597	-	2e-33	30.65% (310)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_0934	-	8e-29	28.66% (328)	putative acyl-CoA dehydrogenase