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M. avium 104 MAV_0597 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 580911 - 581870
length: 319

SAISEERQMLRETVAALVAKHAGPAAVRTAMESERGYDESLWRLLCEQVGAAALVIPEELGGAGGELADA
ATVLQELGRALVPSPLLGTTLAELALLGAAEPDTAALQALAEGSAIGALVLDPDYVVNGDIADVVIGVED
GRLSRWTGVTAQPVTTMDPTRRLARVRAQQTEPIGTDPGLADTAAVLLAAEQIGAAEQCLARTVEYAKDR
VQFGRPIGSFQALKHRMADLYVTVAAAKAVVDEACLDPSPTNAATARLAATEALNVVAAEGIQLHGGIAI
TWEHDMHLYFKRAHGSAHLLDTPQQLLTRLEPEVLATP*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_0597 - - 100% (319) putative acyl-CoA dehydrogenase
M. avium 104 MAV_2570 - 6e-41 34.38% (381) putative acyl-CoA dehydrogenase
M. avium 104 MAV_1838 - 1e-38 31.89% (370) acyl-CoA dehydrogenase protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3594 fadE33 1e-144 80.57% (314) acyl-CoA dehydrogenase FADE33
M. gilvum PYR-GCK Mflv_1477 - 1e-124 70.83% (312) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3564 fadE33 1e-144 80.57% (314) acyl-CoA dehydrogenase FADE33
M. leprae Br4923 MLBr_00737 fadE25 6e-14 24.79% (355) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0593c - 1e-106 66.01% (306) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5053 fadE33 1e-139 80.51% (313) acyl-CoA dehydrogenase FadE33
M. smegmatis MC2 155 MSMEG_6016 - 1e-115 67.63% (312) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2066 fadE33 1e-122 69.65% (313) PROBABLE ACYL-CoA DEHYDROGENASE FADE33
M. ulcerans Agy99 MUL_4129 fadE33 1e-138 79.87% (313) acyl-CoA dehydrogenase FadE33
M. vanbaalenii PYR-1 Mvan_5289 - 1e-122 70.51% (312) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3594|M.bovis_AF2122/97            MTPP------------EERQMLRETVASLVAKHAGPAAVRAAMASDRGYD
Rv3564|M.tuberculosis_H37Rv         MTPP------------EERQMLRETVASLVAKHAGPAAVRAAMASDRGYD
MMAR_5053|M.marinum_M               MT--------------EEREMLRETVAALVNKHASPAAVRSAMESERGYD
MUL_4129|M.ulcerans_Agy99           MT--------------EEREMLRETVAALVNKHASPAAVRSAMESERGYD
MAV_0597|M.avium_104                MSAIS-----------EERQMLRETVAALVAKHAGPAAVRTAMESERGYD
Mflv_1477|M.gilvum_PYR-GCK          MS--------------EERELLRDTVAALVEKHASPEAVRTAAASERGYD
Mvan_5289|M.vanbaalenii_PYR-1       MS--------------EERDLLRDTVAALVDKHASPEAVRKAAASERGYD
TH_2066|M.thermoresistible__bu      MS--------------EERDLLRDTVATLVDKHATSAAVREAMASERGYD
MSMEG_6016|M.smegmatis_MC2_155      MS--------------EERELLRETVAALVEKHASPEAVRAAMESELGYD
MAB_0593c|M.abscessus_ATCC_199      MSPSGN----------TERQMLRDTVRSLVTKRADSAAVRTAFESERGYD
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRAR--FP
                                    *                *:: ** *: :*. *.  . *.     :   : 

Mb3594|M.bovis_AF2122/97            ESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLG
Rv3564|M.tuberculosis_H37Rv         ESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLG
MMAR_5053|M.marinum_M               ETLWRLLCEQVGAAALVIPEELGGAGGELADAAIVLQELGRALVPSPLLG
MUL_4129|M.ulcerans_Agy99           ETLWRLLCEQVGAAALVIPEELGGAGGELADAAIVLQELGRALVPSPLLG
MAV_0597|M.avium_104                ESLWRLLCEQVGAAALVIPEELGGAGGELADAATVLQELGRALVPSPLLG
Mflv_1477|M.gilvum_PYR-GCK          EALWTMLCEQVGAAALVVPEELGGAGGELADAAVVLEELGKRLVPTPLLG
Mvan_5289|M.vanbaalenii_PYR-1       EALWKMLCEQVGAAALVVPEELGGAGGELGDAAVVLEELGKGLVPTPLLG
TH_2066|M.thermoresistible__bu      ESLWQLLCEQVGAAALVVPEDFGGAGGELGDAAVVLGELARNLVPTPLFG
MSMEG_6016|M.smegmatis_MC2_155      PNLWRLLCEQVGAAALVIPEEFGGAGGELADAAVVLEELGKALVPTPLLG
MAB_0593c|M.abscessus_ATCC_199      ENLWAVLCEQVGAAALLIPEESGGAGGELADAAVVVEELGRGLVPSPLMG
MLBr_00737|M.leprae_Br4923          EEALAALNAS-GFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIP
                                          *  . *  *: :**: ** *.:   *. *: *:.:  ..:.*: 

Mb3594|M.bovis_AF2122/97            TT----LAELALLAAAKPDAQALTELAQGSAIGALVLDP-----------
Rv3564|M.tuberculosis_H37Rv         TT----LAELALLAAAKPDAQALTELAQGSAIGALVLDP-----------
MMAR_5053|M.marinum_M               TT----LAELALLAAAEPDAKTLAGLAEGSSIGALVLDP-----------
MUL_4129|M.ulcerans_Agy99           TT----LAELALLAAAEPDAKTLAGLAEGSSIGALVLDP-----------
MAV_0597|M.avium_104                TT----LAELALLGAAEPDTAALQALAEGSAIGALVLDP-----------
Mflv_1477|M.gilvum_PYR-GCK          TT----LAELALLSVDAPDAALLEALAEGTSIGTVVFDP-----------
Mvan_5289|M.vanbaalenii_PYR-1       TT----LAELALLSVAEPDAEALAALAEGAAIGTVVFDP-----------
TH_2066|M.thermoresistible__bu      TT----LAELALLASDSPDADALEALAAGASIGAVVFDP-----------
MSMEG_6016|M.smegmatis_MC2_155      TT----LAEIALLSVG--RTEPLEELAEGAKIGTVVFNP-----------
MAB_0593c|M.abscessus_ATCC_199      TL----WAELALLEAG-YEGELLEALAAGESIGAVAFDP-----------
MLBr_00737|M.leprae_Br4923          AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
                                    :        : *          *  **    :.: .:.            

Mb3594|M.bovis_AF2122/97            --------DYVVNGDIADIVVAAT---------------SGQLTRWTRFS
Rv3564|M.tuberculosis_H37Rv         --------DYVVNGDIADIVVAAT---------------SGQLTRWTRFS
MMAR_5053|M.marinum_M               --------DYVLNGDTADVVVAST---------------EGQLSRWTRFS
MUL_4129|M.ulcerans_Agy99           --------DYVLNGDTADVVVAST---------------EGQLSRWTRFS
MAV_0597|M.avium_104                --------DYVVNGDIADVVIGVE---------------DGRLSRWTGVT
Mflv_1477|M.gilvum_PYR-GCK          --------EHVVNGNVADVVIGTD---------------GETLSRWTSFT
Mvan_5289|M.vanbaalenii_PYR-1       --------GYVVNGNVADVVIAAD---------------GDALTRWNAFT
TH_2066|M.thermoresistible__bu      --------DYVVNGDVAEVIIAAD---------------GERLTRWTGCT
MSMEG_6016|M.smegmatis_MC2_155      --------EFVINGDIADIMIAAD---------------GETLTQWDTFT
MAB_0593c|M.abscessus_ATCC_199      --------GYVVNGDIADVVLTVQ---------------GETVCRAGQVT
MLBr_00737|M.leprae_Br4923          TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
                                              ::**  . :                       :      .

Mb3594|M.bovis_AF2122/97            AQPVATMDPTRRLARLQSEETEPLCPD----PG----------------I
Rv3564|M.tuberculosis_H37Rv         AQPVATMDPTRRLARLQSEETEPLCPD----PG----------------I
MMAR_5053|M.marinum_M               AHRVATMDPTRRLAQLRAEETAFLGED----PG----------------L
MUL_4129|M.ulcerans_Agy99           AHRVATMDPTRRLAQLRAEETAFLGEN----PG----------------L
MAV_0597|M.avium_104                AQPVTTMDPTRRLARVRAQQTEPIGTD----PG----------------L
Mflv_1477|M.gilvum_PYR-GCK          ATPSVAMDITRPLASLEVTETSPLGTD----PG----------------L
Mvan_5289|M.vanbaalenii_PYR-1       ATPAVAMDITRPLAAVEATETSPLGAD----PG----------------L
TH_2066|M.thermoresistible__bu      VEPHQTMDPTRRLARVTPGETTDIGAD----PG----------------L
MSMEG_6016|M.smegmatis_MC2_155      AQPKPTMDMTRRLASVIPGATTTLGDD----QG----------------L
MAB_0593c|M.abscessus_ATCC_199      ALALSTLDPTRRLASIAVGAAEPVGTA----PG----------------L
MLBr_00737|M.leprae_Br4923          DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALAT
                                         ::. ..    :    :  :        *                 

Mb3594|M.bovis_AF2122/97            ADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADL
Rv3564|M.tuberculosis_H37Rv         ADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADL
MMAR_5053|M.marinum_M               ADAAAILLAAEQIGAAERCLELTVEYAKSRVQFGRPIGSFQALKHRMADL
MUL_4129|M.ulcerans_Agy99           ADAAGILLAAEQIGAAERCLELTVEYAKSRVQFGRPIGSFQALKHRMADL
MAV_0597|M.avium_104                ADTAAVLLAAEQIGAAEQCLARTVEYAKDRVQFGRPIGSFQALKHRMADL
Mflv_1477|M.gilvum_PYR-GCK          ADIAAILLAAEQVGAASKCLDLTVQYTKDRVQFGRPIGSFQALKHRMADL
Mvan_5289|M.vanbaalenii_PYR-1       ADTAAILLAAEQIGAATRCLELTVQYTKDRVQFGRPIGSFQALKHRMADL
TH_2066|M.thermoresistible__bu      ADTAALLLAAEQIAAAERCLQLTVDYTKERVQFGRPIGSFQALKHRMADL
MSMEG_6016|M.smegmatis_MC2_155      ADTAALLMAAEQIGAASRCLDLTVAYSKDRVQFGRPIGSFQALKHRMADL
MAB_0593c|M.abscessus_ATCC_199      IDKAGLLLAAEQVGAAARALDLTVEYTKTRVQFGRAIGSFQALKHRMADL
MLBr_00737|M.leprae_Br4923          LDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADM
                                     * :   :.*: :. *  .*  :: *:* * ***..*.:**:::. :**:

Mb3594|M.bovis_AF2122/97            YVTIAAARAVVADACHAPTPTN------AATARLAASEALSTAAAEGIQL
Rv3564|M.tuberculosis_H37Rv         YVTIAAARAVVADACHAPTPTN------AATARLAASEALSTAAAEGIQL
MMAR_5053|M.marinum_M               YVEVAAARAVVTEACTAPTPTS------AATARLAACEALCAVAAEGIQL
MUL_4129|M.ulcerans_Agy99           YVEVAAARAVVTEACTAPTPTS------AATARLAACEALCAVAAEGIQL
MAV_0597|M.avium_104                YVTVAAAKAVVDEACLDPSPTN------AATARLAATEALNVVAAEGIQL
Mflv_1477|M.gilvum_PYR-GCK          YVAVQSAKAVVDEAVAEPSSTS------AALARLAATEAFSKTAAEAVQM
Mvan_5289|M.vanbaalenii_PYR-1       YVAVQSAKAVVDEAVAEPTATS------AALARLAAGEAFSKVAAEAVQM
TH_2066|M.thermoresistible__bu      YVRVQSTRAVVDEAIAEPSATS------AALARFSASETFSAVAAEAVQM
MSMEG_6016|M.smegmatis_MC2_155      YVKVASARAVVHDSIATPSSTS------AALARYFASEALSAVTSEAVQI
MAB_0593c|M.abscessus_ATCC_199      YVLVESARATVYQAIHDLTPEG------ATVARIKASEALSAVSGDSIQL
MLBr_00737|M.leprae_Br4923          AMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQL
                                     : : :::  *  :              :: ::  * :    .: :.:*:

Mb3594|M.bovis_AF2122/97            HGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWES-P---
Rv3564|M.tuberculosis_H37Rv         HGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWES-P---
MMAR_5053|M.marinum_M               HGGIAITWEHDMHLYFKRAHGSTHLLASPPELLRRLESEALGAGPSIP
MUL_4129|M.ulcerans_Agy99           HGGIAITWEHDMHLYFKRAHGSTHLLASPPELLRRLESEALGAGPSIP
MAV_0597|M.avium_104                HGGIAITWEHDMHLYFKRAHGSAHLLDTPQQLLTRLEPEVLAT-P---
Mflv_1477|M.gilvum_PYR-GCK          HGGIAITWESDIQLYFKRAHGSAQLLPPPREQLRRLESEVF-------
Mvan_5289|M.vanbaalenii_PYR-1       HGGIAITWESDIQLYFKRAHGSAQLFGPPREQLRRLEAQVF-------
TH_2066|M.thermoresistible__bu      HGGIAITWEHDIQLYFKRAHGSAQLFGPPREHLRRLESEIL-------
MSMEG_6016|M.smegmatis_MC2_155      HGGIAITWEHDIQLYFKRAHGSAQLLGPPREQLRRLEAEVF-------
MAB_0593c|M.abscessus_ATCC_199      HGGIAITWEHDAHLYFKRAHGSALLLGTPRQLLPNLETAAGL------
MLBr_00737|M.leprae_Br4923          FGGAGYTSDFPVERFMRDAK-ITQIYEGTNQIQRVVMSRALLR-----
                                    .** . * :   . ::: *:  : :   . :    : .

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_0597	-	-	100% (319)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_2570	-	6e-41	34.38% (381)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_1838	-	1e-38	31.89% (370)	acyl-CoA dehydrogenase protein