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IMPVDTSALPSNWGRWGTTDELGTLNLVTDAVRARAAAEVQTGQSVSLARPIDPAPFAAGPFAPVTSASP AVQQAVMFTGSPPLAMAELLVVTTHHRSLTHLDAVVHKPVDGYVYPGVPLAEAAVPFGVRRGSTSAFAAG ILTRGVLLDLAPNTRLPEGHPVTAADFTAAEEREQVRLEPGDALIVRGGWSAASDHDAALPGITLDAVRW MHERDVAAYAGDIGDGHPPVDPEVTSPLHGVALARLGMPLIDVAEVDELATRCAALGRFAFLLSAAPPRI GSLTGVPVNPIAIF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0484 | - | - | 100% (295) | cyclase |
| M. avium 104 | MAV_0883 | - | 1e-29 | 31.43% (315) | putative cyclase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2406 | - | 5e-28 | 29.56% (318) | hypothetical protein Mflv_2406 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3566c | - | 2e-28 | 30.67% (313) | putative cyclase |
| M. marinum M | MMAR_4772 | - | 1e-27 | 29.43% (316) | hypothetical protein MMAR_4772 |
| M. smegmatis MC2 155 | MSMEG_4048 | - | 4e-34 | 33.99% (306) | cyclase |
| M. thermoresistible (build 8) | TH_0900 | - | 7e-28 | 32.70% (318) | cyclase |
| M. ulcerans Agy99 | MUL_0343 | - | 9e-28 | 29.43% (316) | hypothetical protein MUL_0343 |
| M. vanbaalenii PYR-1 | Mvan_4240 | - | 3e-28 | 29.87% (318) | hypothetical protein Mvan_4240 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2406|M.gilvum_PYR-GCK ------MTGTMA-DFRKAADEV----RNWGRWGDDDEVGTLNFITPEKVA
Mvan_4240|M.vanbaalenii_PYR-1 ------MTGTMK-DFRRVADEV----RNWGRWGDDDEVGTLNFITPAKVA
TH_0900|M.thermoresistible__bu --VKPMSTASMT-EFRRVADQV----RNWGRWGTDDELGTLNFITAEKVT
MMAR_4772|M.marinum_M -------MADMT-EFRRVAREL----SNWGRWGDADELGTLNFITAEKVQ
MUL_0343|M.ulcerans_Agy99 ------MMADMT-EFRRVAREL----SNWGRWGDADELGTLNFITAEKVQ
MSMEG_4048|M.smegmatis_MC2_155 MTQLHTSTADLGGDAVKLVDELCLKYRNWGRWGEDDERGTLNFITPAAIA
MAB_3566c|M.abscessus_ATCC_199 ----------MGDDLAVLESYIQR-CSNWGRWGSQDQLGTVNLITQEKIR
MAV_0484|M.avium_104 -------------MIMPVDTSALP--SNWGRWGTTDELGTLNLVTDAVRA
****** *: **:*::*
Mflv_2406|M.gilvum_PYR-GCK EAARLVTQGKVISLGGDFSSGGPQ-GAFKFRQNPVHVMTVDGGDASTLVE
Mvan_4240|M.vanbaalenii_PYR-1 EAAGLVKQGKVISLGGDFSSGGPQ-GAFKFRQNPVHVMTVDGGDASTLVE
TH_0900|M.thermoresistible__bu EAAGLVRQGKVFALGGDFGSAGPQ-GAFQFRQNPVHVMTVDGGDINTLAQ
MMAR_4772|M.marinum_M RAASLVRHGKVFALGVDFGSSGPQ-GAFGFRHNPIHLMTIDGGDASSLAQ
MUL_0343|M.ulcerans_Agy99 RAASLVRHGKVFALGVDFGSSGPQ-GAFGFRHNPIHLMTIDGGDASSLAQ
MSMEG_4048|M.smegmatis_MC2_155 EAAALVRTGTVVSCALPFNGDGPQAGGFGGRTNPIHSMLQDGGDIALGAQ
MAB_3566c|M.abscessus_ATCC_199 EAATLVKVGKTISLTMAYDADGPQ-NGYLGRANPQLYQLTSGPGYLVGEQ
MAV_0484|M.avium_104 RAAAEVQTGQSVSLARPIDPAPFAAGPFAPVTSASPAVQQAVMFTGSPPL
.** * * .: . . : ..
Mflv_2406|M.gilvum_PYR-GCK YGPKWLRNAVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYED
Mvan_4240|M.vanbaalenii_PYR-1 YGPQWLRNAVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYED
TH_0900|M.thermoresistible__bu YGPQWLRNSVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYDD
MMAR_4772|M.marinum_M YGPGWEQNPTAREMGKYVVDNPFRFNDDMIIMPLQAATQWDALSHVYYDD
MUL_0343|M.ulcerans_Agy99 YGPGWEQNPTAREMGKYLVDNPFRFNDDMIIMPLQAATQWDALSHVYYDD
MSMEG_4048|M.smegmatis_MC2_155 DHLDILR-----------------YCDDAVSMPLQCGTQWDALAHIFYRG
MAB_3566c|M.abscessus_ATCC_199 QQVETQTLTELRKTSG---EPTAGYYDDVLVMPTQSGTQWDALCHFFWRG
MAV_0484|M.avium_104 AMAELLV----------------------VTTHHRSLTHLDAVVHKPVDG
: :. *: **: * .
Mflv_2406|M.gilvum_PYR-GCK KLYNGFPADSVTSFGAFHLGIEKVDRKGITSRGVLLDVVAHRGADVFCEP
Mvan_4240|M.vanbaalenii_PYR-1 KLYNGFPADSVTSFGAFHLGIEKVDNKGITSRGVLLDVVAHRGVDTFCQP
TH_0900|M.thermoresistible__bu QLYNGFPAGSVTSFGAFHCGIDKVDHKGITSRGVLLDVVRHRGAEVFLEP
MMAR_4772|M.marinum_M QLYNGFPADSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEH
MUL_0343|M.ulcerans_Agy99 QLYNGFPADSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEH
MSMEG_4048|M.smegmatis_MC2_155 QMYNGHGLESVTSSGATANSIDKVAD-GIAGRGVLLDVARHHDVP-WLEA
MAB_3566c|M.abscessus_ATCC_199 KMYNGHRVADAGTGGSRSNGVQNYTG-RIITRGVFVDLAEYWGVE-TLDP
MAV_0484|M.avium_104 YVYPGVPLAEAAVPFGVRRGSTSAFAAGILTRGVLLDLAPN----TRLPE
:* * .. . . . * ***::*:.
Mflv_2406|M.gilvum_PYR-GCK GEPITPDELDEIVARQQVEIRSGDIVVVHTGWWTRFLATRDG----GEAG
Mvan_4240|M.vanbaalenii_PYR-1 GAPITPDELDEIVARQNVEIRSGDIVVVHTGWWTRFLSTGDG----GEAG
TH_0900|M.thermoresistible__bu GQPVTPEELDEVAAAQGVTIRSGDIVVVHTGWWTRFLSTGDG----AEPG
MMAR_4772|M.marinum_M GNPITPEELDDVARSQGVTIESGDIVLIRTGWWTRFLMTANK----TEPY
MUL_0343|M.ulcerans_Agy99 GNPITPEELDDVARSQGVTIESGDIVLIRTGWWTRFLMTANK----TEPY
MSMEG_4048|M.smegmatis_MC2_155 GHAINSADLTACADQQGVSICSGDIVLIRTGQLAQVRAEGTWGAYDSGPA
MAB_3566c|M.abscessus_ATCC_199 GYPITTADLDDYLAAKKLEIRSGDALIIRTGFMAARRGNWRD--YAGGAA
MAV_0484|M.avium_104 GHPVTAADFTAAEEREQVRLEPGDALIVRGGWSAASDH--------DAAL
* .:.. :: : : : .** :::: * : .
Mflv_2406|M.gilvum_PYR-GCK SGLHWTCAKWLHRHEVAAVASDNLMVEDPNPANGVEGTFLPMHMLCLRDM
Mvan_4240|M.vanbaalenii_PYR-1 SGLHWTCASWLHEHEVAAVAADNLMVEDPDPGNGVEGTFLPMHMLCLRDM
TH_0900|M.thermoresistible__bu SGLHWRCAIWLHEHEVAAVAADNLMVEDPDPANGVEGTFLPMHMLCLRDM
MMAR_4772|M.marinum_M SGLDWRCAQWLHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDM
MUL_0343|M.ulcerans_Agy99 SGLDWRCAQWLHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDM
MSMEG_4048|M.smegmatis_MC2_155 PGLGVDSAHWFVEHEIAALATDTWGAEVQ--PNDTPGVFQPLHLILLANA
MAB_3566c|M.abscessus_ATCC_199 PGLSLHTAPWLRDHDIAAVATDTWGIEVL--PNEID-VWQPLHVVSLVHT
MAV_0484|M.avium_104 PGITLDAVRWMHERDVAAYAGDIGDGHPP----VDPEVTSPLHGVALARL
.*: . *: :::** * * . *:* : *
Mflv_2406|M.gilvum_PYR-GCK GLMLGEYWDLGPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
Mvan_4240|M.vanbaalenii_PYR-1 GLMLGEYWDLGPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
TH_0900|M.thermoresistible__bu GLMLGEYWDLTDLAADCAADGVYEFQLIAPPLRVIGAVGSPVNPIAIK
MMAR_4772|M.marinum_M GLMLGEYWDLTALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MUL_0343|M.ulcerans_Agy99 GLMLGEYWDLTALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MSMEG_4048|M.smegmatis_MC2_155 GMTIGEIFDLERLADVCRQQERYEFFFVAPPLPITAAVGSPVNPLAIF
MAB_3566c|M.abscessus_ATCC_199 GLAFGEMFDLDGLSEDTKTDGVYEFMFVASPLPLTGASGSPVSALAIK
MAV_0484|M.avium_104 GMPLIDVAEVDELATRCAALGRFAFLLSAAPPRIGSLTGVPVNPIAIF
*: : : :: *: : * : *.* . . * **..:**