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TGTMKDFRRVADEVRNWGRWGDDDEVGTLNFITPAKVAEAAGLVKQGKVISLGGDFSSGGPQGAFKFRQN PVHVMTVDGGDASTLVEYGPQWLRNAVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLY NGFPADSVTSFGAFHLGIEKVDNKGITSRGVLLDVVAHRGVDTFCQPGAPITPDELDEIVARQNVEIRSG DIVVVHTGWWTRFLSTGDGGEAGSGLHWTCASWLHEHEVAAVAADNLMVEDPDPGNGVEGTFLPMHMLCL RDMGLMLGEYWDLGPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4240 | - | - | 100% (332) | hypothetical protein Mvan_4240 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2406 | - | 0.0 | 93.98% (332) | hypothetical protein Mflv_2406 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3566c | - | 2e-54 | 38.20% (322) | putative cyclase |
| M. marinum M | MMAR_4772 | - | 1e-140 | 70.43% (328) | hypothetical protein MMAR_4772 |
| M. avium 104 | MAV_0883 | - | 1e-139 | 70.52% (329) | putative cyclase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_4861 | - | 1e-160 | 79.88% (328) | cyclase |
| M. thermoresistible (build 8) | TH_0900 | - | 1e-168 | 81.87% (331) | cyclase |
| M. ulcerans Agy99 | MUL_0343 | - | 1e-141 | 69.88% (332) | hypothetical protein MUL_0343 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4240|M.vanbaalenii_PYR-1 ----MTGTMKDFRRVADEVRNWGRWGDDDEVGTLNFITPAKVAEAAGLVK
Mflv_2406|M.gilvum_PYR-GCK ----MTGTMADFRKAADEVRNWGRWGDDDEVGTLNFITPEKVAEAARLVT
MSMEG_4861|M.smegmatis_MC2_155 --------MTDFRRVAHDVCNWGRWGEADELGTLNFITADKVAEAASLVK
TH_0900|M.thermoresistible__bu VKPMSTASMTEFRRVADQVRNWGRWGTDDELGTLNFITAEKVTEAAGLVR
MMAR_4772|M.marinum_M -----MADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVR
MUL_0343|M.ulcerans_Agy99 ----MMADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVR
MAV_0883|M.avium_104 -----MASVTDFRRAARDVSNWGRWGDDDELGTLNFITEEKIAQAASLVQ
MAB_3566c|M.abscessus_ATCC_199 ----MGDDLAVLESYIQRCSNWGRWGSQDQLGTVNLITQEKIREAATLVK
: :. ****** *::**:*:** *: .** **
Mvan_4240|M.vanbaalenii_PYR-1 QGKVISLGGDFSSGGPQGAFKFRQNPVHVMTVDGGDASTLVEYGPQWLRN
Mflv_2406|M.gilvum_PYR-GCK QGKVISLGGDFSSGGPQGAFKFRQNPVHVMTVDGGDASTLVEYGPKWLRN
MSMEG_4861|M.smegmatis_MC2_155 QGKVFALGADFGSAGPQGAFQFRQNPTHVMTVDGGDAATLTKYGPQWLLN
TH_0900|M.thermoresistible__bu QGKVFALGGDFGSAGPQGAFQFRQNPVHVMTVDGGDINTLAQYGPQWLRN
MMAR_4772|M.marinum_M HGKVFALGVDFGSSGPQGAFGFRHNPIHLMTIDGGDASSLAQYGPGWEQN
MUL_0343|M.ulcerans_Agy99 HGKVFALGVDFGSSGPQGAFGFRHNPIHLMTIDGGDASSLAQYGPGWEQN
MAV_0883|M.avium_104 HGKVFPLGVDFGSSGPQGAFGFRHNPIHVMTVDGGDAATLAQYGPGWDRN
MAB_3566c|M.abscessus_ATCC_199 VGKTISLTMAYDADGPQNGYLGRANP-QLYQLTSGPGYLVGEQ--QQVET
**.:.* :.: ***..: * ** :: : .* : : .
Mvan_4240|M.vanbaalenii_PYR-1 AVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLYNGFPA
Mflv_2406|M.gilvum_PYR-GCK AVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLYNGFPA
MSMEG_4861|M.smegmatis_MC2_155 SVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYEDRLYNGFPA
TH_0900|M.thermoresistible__bu SVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYDDQLYNGFPA
MMAR_4772|M.marinum_M PTAREMGKYVVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLYNGFPA
MUL_0343|M.ulcerans_Agy99 PTAREMGKYLVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLYNGFPA
MAV_0883|M.avium_104 PTAAQMGPYFVDNLFRFNDDMIIMPLQAATQWDALSHVYYDDLLYNGVPA
MAB_3566c|M.abscessus_ATCC_199 QTLTELRKTSGEPTAGYYDDVLVMPTQSGTQWDALCHFFWRGKMYNGHRV
. :: : : **:::** *:.*****:.*.:: . :*** .
Mvan_4240|M.vanbaalenii_PYR-1 DSVTSFGAFHLGIEKVDNKGITSRGVLLDVVAHRGVDTFCQPGAPITPDE
Mflv_2406|M.gilvum_PYR-GCK DSVTSFGAFHLGIEKVDRKGITSRGVLLDVVAHRGADVFCEPGEPITPDE
MSMEG_4861|M.smegmatis_MC2_155 DSVTSFGAFHCSIDKVDVKGITSRGVLLDVVRHRGAEVFLEPGNPVTPEE
TH_0900|M.thermoresistible__bu GSVTSFGAFHCGIDKVDHKGITSRGVLLDVVRHRGAEVFLEPGQPVTPEE
MMAR_4772|M.marinum_M DSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEE
MUL_0343|M.ulcerans_Agy99 DSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEE
MAV_0883|M.avium_104 GSVTSLGARRLGIEKVDGKGITSRGVLLDLVRHRGAAVFLEHGNPITPEE
MAB_3566c|M.abscessus_ATCC_199 ADAGTGGSRSNGVQNYTGR-IITRGVFVDLAEYWGVET-LDPGYPITTAD
.. : *: .::: : * :***::*:. : *. . : * *:*. :
Mvan_4240|M.vanbaalenii_PYR-1 LDEIVARQNVEIRSGDIVVVHTGWWTRFLSTG--DGGEAGSGLHWTCASW
Mflv_2406|M.gilvum_PYR-GCK LDEIVARQQVEIRSGDIVVVHTGWWTRFLATR--DGGEAGSGLHWTCAKW
MSMEG_4861|M.smegmatis_MC2_155 LDAVAAAQGVQIRRGDIVVVHTGWWTRFLSAG--DGAEPGSGLDWRCASW
TH_0900|M.thermoresistible__bu LDEVAAAQGVTIRSGDIVVVHTGWWTRFLSTG--DGAEPGSGLHWRCAIW
MMAR_4772|M.marinum_M LDDVARSQGVTIESGDIVLIRTGWWTRFLMTA--NKTEPYSGLDWRCAQW
MUL_0343|M.ulcerans_Agy99 LDDVARSQGVTIESGDIVLIRTGWWTRFLMTA--NKTEPYSGLDWRCAQW
MAV_0883|M.avium_104 LDDVVRAQGVTIERGDILLIRTGWWTRYLETG--NKTEPYSGLDWRCAQW
MAB_3566c|M.abscessus_ATCC_199 LDDYLAAKKLEIRSGDALIIRTGFMAARRGNWRDYAGGAAPGLSLHTAPW
** : : *. ** ::::**: : . .** * *
Mvan_4240|M.vanbaalenii_PYR-1 LHEHEVAAVAADNLMVEDPDPGNGVEGTFLPMHMLCLRDMGLMLGEYWDL
Mflv_2406|M.gilvum_PYR-GCK LHRHEVAAVASDNLMVEDPNPANGVEGTFLPMHMLCLRDMGLMLGEYWDL
MSMEG_4861|M.smegmatis_MC2_155 LHDHEVAAVAADNLMVEDPDPASGVEGTFLPMHMLCLRDMGLMLGEYWDL
TH_0900|M.thermoresistible__bu LHEHEVAAVAADNLMVEDPDPANGVEGTFLPMHMLCLRDMGLMLGEYWDL
MMAR_4772|M.marinum_M LHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDMGLMLGEYWDL
MUL_0343|M.ulcerans_Agy99 LHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDMGLMLGEYWDL
MAV_0883|M.avium_104 LHDHEVAAVASDNLQVEDP--VSGVDGVFLPFHLLTLRDMGLMLGEYWDL
MAB_3566c|M.abscessus_ATCC_199 LRDHDIAAVATDTWGIEVLP--NEID-VWQPLHVVSLVHTGLAFGEMFDL
*: *::****:*. :* . :: : *:*:: * . ** :** :**
Mvan_4240|M.vanbaalenii_PYR-1 GPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
Mflv_2406|M.gilvum_PYR-GCK GPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
MSMEG_4861|M.smegmatis_MC2_155 TALSADCAADGVYEFQLIAPPLRVTGAVGSPVNPIAIK
TH_0900|M.thermoresistible__bu TDLAADCAADGVYEFQLIAPPLRVIGAVGSPVNPIAIK
MMAR_4772|M.marinum_M TALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MUL_0343|M.ulcerans_Agy99 TALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MAV_0883|M.avium_104 SALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MAB_3566c|M.abscessus_ATCC_199 DGLSEDTKTDGVYEFMFVASPLPLTGASGSPVSALAIK
*: * :****** ::*.** . ** *:**..:***