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M. gilvum PYR-GCK Mflv_2406 (-)

annotation: hypothetical protein Mflv_2406
coordinates: 2506122 - 2507120
length: 332

MTGTMADFRKAADEVRNWGRWGDDDEVGTLNFITPEKVAEAARLVTQGKVISLGGDFSSGGPQGAFKFRQ
NPVHVMTVDGGDASTLVEYGPKWLRNAVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKL
YNGFPADSVTSFGAFHLGIEKVDRKGITSRGVLLDVVAHRGADVFCEPGEPITPDELDEIVARQQVEIRS
GDIVVVHTGWWTRFLATRDGGEAGSGLHWTCAKWLHRHEVAAVASDNLMVEDPNPANGVEGTFLPMHMLC
LRDMGLMLGEYWDLGPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2406--100% (332)hypothetical protein Mflv_2406

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3566c-2e-5438.08% (323) putative cyclase
M. marinum MMMAR_4772-1e-14171.34% (328) hypothetical protein MMAR_4772
M. avium 104MAV_0883-1e-14071.73% (329) putative cyclase superfamily protein
M. smegmatis MC2 155MSMEG_4861-1e-15778.35% (328) cyclase
M. thermoresistible (build 8)TH_0900-1e-16580.66% (331) cyclase
M. ulcerans Agy99MUL_0343-1e-14270.78% (332) hypothetical protein MUL_0343
M. vanbaalenii PYR-1Mvan_4240-0.093.98% (332) hypothetical protein Mvan_4240

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2406|M.gilvum_PYR-GCK          ----MTGTMADFRKAADEVRNWGRWGDDDEVGTLNFITPEKVAEAARLVT
Mvan_4240|M.vanbaalenii_PYR-1       ----MTGTMKDFRRVADEVRNWGRWGDDDEVGTLNFITPAKVAEAAGLVK
MSMEG_4861|M.smegmatis_MC2_155      --------MTDFRRVAHDVCNWGRWGEADELGTLNFITADKVAEAASLVK
TH_0900|M.thermoresistible__bu      VKPMSTASMTEFRRVADQVRNWGRWGTDDELGTLNFITAEKVTEAAGLVR
MMAR_4772|M.marinum_M               -----MADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVR
MUL_0343|M.ulcerans_Agy99           ----MMADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVR
MAV_0883|M.avium_104                -----MASVTDFRRAARDVSNWGRWGDDDELGTLNFITEEKIAQAASLVQ
MAB_3566c|M.abscessus_ATCC_199      ----MGDDLAVLESYIQRCSNWGRWGSQDQLGTVNLITQEKIREAATLVK
                                            :  :.       ******  *::**:*:**  *: .** ** 

Mflv_2406|M.gilvum_PYR-GCK          QGKVISLGGDFSSGGPQGAFKFRQNPVHVMTVDGGDASTLVEYGPKWLRN
Mvan_4240|M.vanbaalenii_PYR-1       QGKVISLGGDFSSGGPQGAFKFRQNPVHVMTVDGGDASTLVEYGPQWLRN
MSMEG_4861|M.smegmatis_MC2_155      QGKVFALGADFGSAGPQGAFQFRQNPTHVMTVDGGDAATLTKYGPQWLLN
TH_0900|M.thermoresistible__bu      QGKVFALGGDFGSAGPQGAFQFRQNPVHVMTVDGGDINTLAQYGPQWLRN
MMAR_4772|M.marinum_M               HGKVFALGVDFGSSGPQGAFGFRHNPIHLMTIDGGDASSLAQYGPGWEQN
MUL_0343|M.ulcerans_Agy99           HGKVFALGVDFGSSGPQGAFGFRHNPIHLMTIDGGDASSLAQYGPGWEQN
MAV_0883|M.avium_104                HGKVFPLGVDFGSSGPQGAFGFRHNPIHVMTVDGGDAATLAQYGPGWDRN
MAB_3566c|M.abscessus_ATCC_199      VGKTISLTMAYDADGPQNGYLGRANP-QLYQLTSGPGYLVGEQ--QQVET
                                     **.:.*   :.: ***..:  * ** ::  : .*    : :       .

Mflv_2406|M.gilvum_PYR-GCK          AVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLYNGFPA
Mvan_4240|M.vanbaalenii_PYR-1       AVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLYNGFPA
MSMEG_4861|M.smegmatis_MC2_155      SVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYEDRLYNGFPA
TH_0900|M.thermoresistible__bu      SVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYDDQLYNGFPA
MMAR_4772|M.marinum_M               PTAREMGKYVVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLYNGFPA
MUL_0343|M.ulcerans_Agy99           PTAREMGKYLVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLYNGFPA
MAV_0883|M.avium_104                PTAAQMGPYFVDNLFRFNDDMIIMPLQAATQWDALSHVYYDDLLYNGVPA
MAB_3566c|M.abscessus_ATCC_199      QTLTELRKTSGEPTAGYYDDVLVMPTQSGTQWDALCHFFWRGKMYNGHRV
                                     .  ::     :    : **:::** *:.*****:.*.:: . :***  .

Mflv_2406|M.gilvum_PYR-GCK          DSVTSFGAFHLGIEKVDRKGITSRGVLLDVVAHRGADVFCEPGEPITPDE
Mvan_4240|M.vanbaalenii_PYR-1       DSVTSFGAFHLGIEKVDNKGITSRGVLLDVVAHRGVDTFCQPGAPITPDE
MSMEG_4861|M.smegmatis_MC2_155      DSVTSFGAFHCSIDKVDVKGITSRGVLLDVVRHRGAEVFLEPGNPVTPEE
TH_0900|M.thermoresistible__bu      GSVTSFGAFHCGIDKVDHKGITSRGVLLDVVRHRGAEVFLEPGQPVTPEE
MMAR_4772|M.marinum_M               DSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEE
MUL_0343|M.ulcerans_Agy99           DSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEE
MAV_0883|M.avium_104                GSVTSLGARRLGIEKVDGKGITSRGVLLDLVRHRGAAVFLEHGNPITPEE
MAB_3566c|M.abscessus_ATCC_199      ADAGTGGSRSNGVQNYTGR-IITRGVFVDLAEYWGVET-LDPGYPITTAD
                                     .. : *:   .:::   : * :***::*:. : *. .  : * *:*. :

Mflv_2406|M.gilvum_PYR-GCK          LDEIVARQQVEIRSGDIVVVHTGWWTRFLATR--DGGEAGSGLHWTCAKW
Mvan_4240|M.vanbaalenii_PYR-1       LDEIVARQNVEIRSGDIVVVHTGWWTRFLSTG--DGGEAGSGLHWTCASW
MSMEG_4861|M.smegmatis_MC2_155      LDAVAAAQGVQIRRGDIVVVHTGWWTRFLSAG--DGAEPGSGLDWRCASW
TH_0900|M.thermoresistible__bu      LDEVAAAQGVTIRSGDIVVVHTGWWTRFLSTG--DGAEPGSGLHWRCAIW
MMAR_4772|M.marinum_M               LDDVARSQGVTIESGDIVLIRTGWWTRFLMTA--NKTEPYSGLDWRCAQW
MUL_0343|M.ulcerans_Agy99           LDDVARSQGVTIESGDIVLIRTGWWTRFLMTA--NKTEPYSGLDWRCAQW
MAV_0883|M.avium_104                LDDVVRAQGVTIERGDILLIRTGWWTRYLETG--NKTEPYSGLDWRCAQW
MAB_3566c|M.abscessus_ATCC_199      LDDYLAAKKLEIRSGDALIIRTGFMAARRGNWRDYAGGAAPGLSLHTAPW
                                    **     : : *. ** ::::**: :            . .**    * *

Mflv_2406|M.gilvum_PYR-GCK          LHRHEVAAVASDNLMVEDPNPANGVEGTFLPMHMLCLRDMGLMLGEYWDL
Mvan_4240|M.vanbaalenii_PYR-1       LHEHEVAAVAADNLMVEDPDPGNGVEGTFLPMHMLCLRDMGLMLGEYWDL
MSMEG_4861|M.smegmatis_MC2_155      LHDHEVAAVAADNLMVEDPDPASGVEGTFLPMHMLCLRDMGLMLGEYWDL
TH_0900|M.thermoresistible__bu      LHEHEVAAVAADNLMVEDPDPANGVEGTFLPMHMLCLRDMGLMLGEYWDL
MMAR_4772|M.marinum_M               LHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDMGLMLGEYWDL
MUL_0343|M.ulcerans_Agy99           LHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDMGLMLGEYWDL
MAV_0883|M.avium_104                LHDHEVAAVASDNLQVEDP--VSGVDGVFLPFHLLTLRDMGLMLGEYWDL
MAB_3566c|M.abscessus_ATCC_199      LRDHDIAAVATDTWGIEVLP--NEID-VWQPLHVVSLVHTGLAFGEMFDL
                                    *: *::****:*.  :*     . ::  : *:*:: * . ** :** :**

Mflv_2406|M.gilvum_PYR-GCK          GPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
Mvan_4240|M.vanbaalenii_PYR-1       GPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
MSMEG_4861|M.smegmatis_MC2_155      TALSADCAADGVYEFQLIAPPLRVTGAVGSPVNPIAIK
TH_0900|M.thermoresistible__bu      TDLAADCAADGVYEFQLIAPPLRVIGAVGSPVNPIAIK
MMAR_4772|M.marinum_M               TALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MUL_0343|M.ulcerans_Agy99           TALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MAV_0883|M.avium_104                SALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MAB_3566c|M.abscessus_ATCC_199      DGLSEDTKTDGVYEFMFVASPLPLTGASGSPVSALAIK
                                      *: *  :****** ::*.** . ** *:**..:***