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MADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVRHGKVFALGVDFGSSGPQGAFGFRHN PIHLMTIDGGDASSLAQYGPGWEQNPTAREMGKYLVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLY NGFPADSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEELDDVARSQGVTIESG DIVLIRTGWWTRFLMTANKTEPYSGLDWRCAQWLHDHEVAAVASDNLQVEDPVSGVDGLFLPLHLLCLRD MGLMLGEYWDLTALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0343 | - | - | 100% (330) | hypothetical protein MUL_0343 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2406 | - | 1e-142 | 70.78% (332) | hypothetical protein Mflv_2406 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3566c | - | 4e-54 | 37.43% (334) | putative cyclase |
| M. marinum M | MMAR_4772 | - | 0.0 | 99.70% (329) | hypothetical protein MMAR_4772 |
| M. avium 104 | MAV_0883 | - | 1e-172 | 86.32% (329) | putative cyclase superfamily protein |
| M. smegmatis MC2 155 | MSMEG_4861 | - | 1e-156 | 77.74% (328) | cyclase |
| M. thermoresistible (build 8) | TH_0900 | - | 1e-157 | 78.18% (330) | cyclase |
| M. vanbaalenii PYR-1 | Mvan_4240 | - | 1e-141 | 69.88% (332) | hypothetical protein Mvan_4240 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0343|M.ulcerans_Agy99 ----MMADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVR
MMAR_4772|M.marinum_M -----MADMTEFRRVARELSNWGRWGDADELGTLNFITAEKVQRAASLVR
MAV_0883|M.avium_104 -----MASVTDFRRAARDVSNWGRWGDDDELGTLNFITEEKIAQAASLVQ
MSMEG_4861|M.smegmatis_MC2_155 --------MTDFRRVAHDVCNWGRWGEADELGTLNFITADKVAEAASLVK
TH_0900|M.thermoresistible__bu VKPMSTASMTEFRRVADQVRNWGRWGTDDELGTLNFITAEKVTEAAGLVR
Mflv_2406|M.gilvum_PYR-GCK ----MTGTMADFRKAADEVRNWGRWGDDDEVGTLNFITPEKVAEAARLVT
Mvan_4240|M.vanbaalenii_PYR-1 ----MTGTMKDFRRVADEVRNWGRWGDDDEVGTLNFITPAKVAEAAGLVK
MAB_3566c|M.abscessus_ATCC_199 ----MGDDLAVLESYIQRCSNWGRWGSQDQLGTVNLITQEKIREAATLVK
: :. ****** *::**:*:** *: .** **
MUL_0343|M.ulcerans_Agy99 HGKVFALGVDFGSSGPQGAFGFRHNPIHLMTIDGGDASSLAQYGPGWEQN
MMAR_4772|M.marinum_M HGKVFALGVDFGSSGPQGAFGFRHNPIHLMTIDGGDASSLAQYGPGWEQN
MAV_0883|M.avium_104 HGKVFPLGVDFGSSGPQGAFGFRHNPIHVMTVDGGDAATLAQYGPGWDRN
MSMEG_4861|M.smegmatis_MC2_155 QGKVFALGADFGSAGPQGAFQFRQNPTHVMTVDGGDAATLTKYGPQWLLN
TH_0900|M.thermoresistible__bu QGKVFALGGDFGSAGPQGAFQFRQNPVHVMTVDGGDINTLAQYGPQWLRN
Mflv_2406|M.gilvum_PYR-GCK QGKVISLGGDFSSGGPQGAFKFRQNPVHVMTVDGGDASTLVEYGPKWLRN
Mvan_4240|M.vanbaalenii_PYR-1 QGKVISLGGDFSSGGPQGAFKFRQNPVHVMTVDGGDASTLVEYGPQWLRN
MAB_3566c|M.abscessus_ATCC_199 VGKTISLTMAYDADGPQNGYLGRANP-QLYQLTSGPGYLVGEQ--QQVET
**.:.* :.: ***..: * ** :: : .* : : .
MUL_0343|M.ulcerans_Agy99 PTAREMGKYLVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLYNGFPA
MMAR_4772|M.marinum_M PTAREMGKYVVDNPFRFNDDMIIMPLQAATQWDALSHVYYDDQLYNGFPA
MAV_0883|M.avium_104 PTAAQMGPYFVDNLFRFNDDMIIMPLQAATQWDALSHVYYDDLLYNGVPA
MSMEG_4861|M.smegmatis_MC2_155 SVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYEDRLYNGFPA
TH_0900|M.thermoresistible__bu SVAHQVSEFFVDNPFRFNDDMIVMPLQAATQWDALSHVYYDDQLYNGFPA
Mflv_2406|M.gilvum_PYR-GCK AVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLYNGFPA
Mvan_4240|M.vanbaalenii_PYR-1 AVAADMSAFFADNPFRFNDDIIVMPLQAATQWDAMSHVYYEDKLYNGFPA
MAB_3566c|M.abscessus_ATCC_199 QTLTELRKTSGEPTAGYYDDVLVMPTQSGTQWDALCHFFWRGKMYNGHRV
. :: : : **:::** *:.*****:.*.:: . :*** .
MUL_0343|M.ulcerans_Agy99 DSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEE
MMAR_4772|M.marinum_M DSVTSLGAYHCGIDKVDVKGITSRGVLLDLVRHRGAEVFLEHGNPITPEE
MAV_0883|M.avium_104 GSVTSLGARRLGIEKVDGKGITSRGVLLDLVRHRGAAVFLEHGNPITPEE
MSMEG_4861|M.smegmatis_MC2_155 DSVTSFGAFHCSIDKVDVKGITSRGVLLDVVRHRGAEVFLEPGNPVTPEE
TH_0900|M.thermoresistible__bu GSVTSFGAFHCGIDKVDHKGITSRGVLLDVVRHRGAEVFLEPGQPVTPEE
Mflv_2406|M.gilvum_PYR-GCK DSVTSFGAFHLGIEKVDRKGITSRGVLLDVVAHRGADVFCEPGEPITPDE
Mvan_4240|M.vanbaalenii_PYR-1 DSVTSFGAFHLGIEKVDNKGITSRGVLLDVVAHRGVDTFCQPGAPITPDE
MAB_3566c|M.abscessus_ATCC_199 ADAGTGGSRSNGVQNYTGR-IITRGVFVDLAEYWGVET-LDPGYPITTAD
.. : *: .::: : * :***::*:. : *. . : * *:*. :
MUL_0343|M.ulcerans_Agy99 LDDVARSQGVTIESGDIVLIRTGWWTRFLMTA--NKTEPYSGLDWRCAQW
MMAR_4772|M.marinum_M LDDVARSQGVTIESGDIVLIRTGWWTRFLMTA--NKTEPYSGLDWRCAQW
MAV_0883|M.avium_104 LDDVVRAQGVTIERGDILLIRTGWWTRYLETG--NKTEPYSGLDWRCAQW
MSMEG_4861|M.smegmatis_MC2_155 LDAVAAAQGVQIRRGDIVVVHTGWWTRFLSAG--DGAEPGSGLDWRCASW
TH_0900|M.thermoresistible__bu LDEVAAAQGVTIRSGDIVVVHTGWWTRFLSTG--DGAEPGSGLHWRCAIW
Mflv_2406|M.gilvum_PYR-GCK LDEIVARQQVEIRSGDIVVVHTGWWTRFLATR--DGGEAGSGLHWTCAKW
Mvan_4240|M.vanbaalenii_PYR-1 LDEIVARQNVEIRSGDIVVVHTGWWTRFLSTG--DGGEAGSGLHWTCASW
MAB_3566c|M.abscessus_ATCC_199 LDDYLAAKKLEIRSGDALIIRTGFMAARRGNWRDYAGGAAPGLSLHTAPW
** : : *. ** ::::**: : . .** * *
MUL_0343|M.ulcerans_Agy99 LHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDMGLMLGEYWDL
MMAR_4772|M.marinum_M LHDHEVAAVASDNLQVEDP--VSGVDGLFLPLHLLCLRDMGLMLGEYWDL
MAV_0883|M.avium_104 LHDHEVAAVASDNLQVEDP--VSGVDGVFLPFHLLTLRDMGLMLGEYWDL
MSMEG_4861|M.smegmatis_MC2_155 LHDHEVAAVAADNLMVEDPDPASGVEGTFLPMHMLCLRDMGLMLGEYWDL
TH_0900|M.thermoresistible__bu LHEHEVAAVAADNLMVEDPDPANGVEGTFLPMHMLCLRDMGLMLGEYWDL
Mflv_2406|M.gilvum_PYR-GCK LHRHEVAAVASDNLMVEDPNPANGVEGTFLPMHMLCLRDMGLMLGEYWDL
Mvan_4240|M.vanbaalenii_PYR-1 LHEHEVAAVAADNLMVEDPDPGNGVEGTFLPMHMLCLRDMGLMLGEYWDL
MAB_3566c|M.abscessus_ATCC_199 LRDHDIAAVATDTWGIEVLP--NEID-VWQPLHVVSLVHTGLAFGEMFDL
*: *::****:*. :* . :: : *:*:: * . ** :** :**
MUL_0343|M.ulcerans_Agy99 TALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MMAR_4772|M.marinum_M TALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MAV_0883|M.avium_104 SALAADCAADGVYEFQLVAPPLRFVGAVGSPVNPIAIK
MSMEG_4861|M.smegmatis_MC2_155 TALSADCAADGVYEFQLIAPPLRVTGAVGSPVNPIAIK
TH_0900|M.thermoresistible__bu TDLAADCAADGVYEFQLIAPPLRVIGAVGSPVNPIAIK
Mflv_2406|M.gilvum_PYR-GCK GPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
Mvan_4240|M.vanbaalenii_PYR-1 GPLAADCAADGVYEFQLVAPPLKVVGAVGAPVSPIAIK
MAB_3566c|M.abscessus_ATCC_199 DGLSEDTKTDGVYEFMFVASPLPLTGASGSPVSALAIK
*: * :****** ::*.** . ** *:**..:***