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VQPGIPVRMTNFGYTLMTEQSGPKELVRYAISAEERGFDFHVCSDHFSPWLTSQGHAPNAWAVLGAVAQA TERVDLYTYVTCPTMRYHPAIVAQQAATVQILSDGRFTLGLGSGENLNEHVVGKGWPTITRRQDMLREAI KIIRELFGGQLVDFTGDYFRVDSARVWDVPDVPVGIGVAIGGTRAVDKFAKLADHLIATEPNADLVDAWH GARQAANLAGGGRVVGQIPVSWDPDPDTAVKRAHDQFRWFAGGWKVNADLPTPAGFAGATQFVRPEDVAD AIPCGPDLDAIVEGVRPYWEAGFTDIALVQIGGDTQERFLKEAAEPLLAALRDAAK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0425 | - | - | 100% (336) | dehydrogenase |
| M. avium 104 | MAV_4761 | - | 4e-42 | 34.73% (334) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. avium 104 | MAV_5172 | - | 4e-39 | 37.12% (264) | F420-dependent glucose-6-phosphate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0415 | fgd1 | 3e-41 | 33.63% (333) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1341 | - | 1e-148 | 74.92% (327) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0407 | fgd1 | 3e-41 | 33.63% (333) | F420-dependent glucose-6-phosphate dehydrogenase |
| M. leprae Br4923 | MLBr_00269 | - | 5e-38 | 32.75% (342) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0947c | - | 1e-122 | 72.76% (279) | putative luciferase |
| M. marinum M | MMAR_0709 | fgd1 | 8e-41 | 33.53% (334) | F420-dependent glucose-6-phosphate dehydrogenase Fgd1 |
| M. smegmatis MC2 155 | MSMEG_1794 | - | 1e-152 | 76.20% (332) | dehydrogenase |
| M. thermoresistible (build 8) | TH_1712 | - | 1e-142 | 70.34% (327) | dehydrogenase |
| M. ulcerans Agy99 | MUL_2814 | fgd1 | 1e-40 | 33.83% (334) | F420-dependent glucose-6-phosphate dehydrogenase Fgd1 |
| M. vanbaalenii PYR-1 | Mvan_5448 | - | 1e-147 | 74.01% (327) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0425|M.avium_104 MQPGIPVRMTNFGYTLMTEQSGPKELVRYAISAEERGFDFHVCSDHFSPW
MSMEG_1794|M.smegmatis_MC2_155 -MHGYPQPMTRFGYTLMTEQSGPKDLVHYAVAAEQAGFDFEVCSDHFSPW
Mflv_1341|M.gilvum_PYR-GCK --------MTRFGYTLMTEQSGPKDLVRYAVSAENVGFDFEVSSDHYFPW
Mvan_5448|M.vanbaalenii_PYR-1 --------MTRFGYTLMTEQSGPKDLVSYAVSAEQVGFDFEVSSDHYFPW
TH_1712|M.thermoresistible__bu --------MTRFGYTLLTEQSGPKDLIRYAVAAERAGFDFELCSDHYSPW
MAB_0947c|M.abscessus_ATCC_199 --------MTRFGYTLMTEQSGPKDLVRYAVAAEKAGFDFEVSSDHYSPW
Mb0415|M.bovis_AF2122/97 ------MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPW
Rv0407|M.tuberculosis_H37Rv ------MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPW
MLBr_00269|M.leprae_Br4923 ------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPW
MMAR_0709|M.marinum_M ------MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPW
MUL_2814|M.ulcerans_Agy99 ------MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPW
.:**. :** .*::*: .::** *:* ***: **
MAV_0425|M.avium_104 LTSQGHAPNAWAVLGAVAQATERVDLYTYVTCPTMRYHPAIVAQQAATVQ
MSMEG_1794|M.smegmatis_MC2_155 LTSQGHAPNAWAVLGAVAHATESAHLYSYVTCPTMRYHPAVVAQQAATVQ
Mflv_1341|M.gilvum_PYR-GCK LSSQGHAPYAWSVLGAVAHATERVELMTYVTCPTVRYHPAIVAQKAATLQ
Mvan_5448|M.vanbaalenii_PYR-1 LASQGHAPYAWSVLGAVAHATDRVELMTYVTCPTMRYHPAIVAQKAATLQ
TH_1712|M.thermoresistible__bu LAAQGHAPYAWSVLGAVAHATDRVELLTFITCPTMRYHPAVVAQKAATLQ
MAB_0947c|M.abscessus_ATCC_199 LSSQGHAPYAWSVLGAVAQATERVDLATYVTCPTMRYHPAVVAQKAATMQ
Mb0415|M.bovis_AF2122/97 RHQGGHAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMG
Rv0407|M.tuberculosis_H37Rv RHQGGHAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMG
MLBr_00269|M.leprae_Br4923 RHQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMG
MMAR_0709|M.marinum_M RHEGGHAPFSLAWMTAVGERTKRMQLGTSVLTPTFRYNPAVIAQAFATMG
MUL_2814|M.ulcerans_Agy99 RHEGGHAPFSLAWMTAVGERTKRMQLGTSVLTPTFRYNPAVIAQAFATMG
***. : : : **.. *. * : : **.**:**::.* **:
MAV_0425|M.avium_104 ILSDGRFTLGLGSGENLNEHVVGKG--WPTITRRQDMLREAIKIIRELFG
MSMEG_1794|M.smegmatis_MC2_155 ILSDGRFTLGLGSGENLNEHVVGKG--WPTVERRLDMLAEAIKIIRELFT
Mflv_1341|M.gilvum_PYR-GCK ILADGRFTLGLGSGENLNEHIVGKG--WPTVARRQDMLSEAIQIIRELQT
Mvan_5448|M.vanbaalenii_PYR-1 LLADGRFTLGLGSGENLNEHVVGKG--WPTVARRHAMLREAIQIIRELHS
TH_1712|M.thermoresistible__bu ILADGRFTLGLGSGENLNEHVVGRR--WPTVARRHDMLREAITIIRGLFS
MAB_0947c|M.abscessus_ATCC_199 ILADGRFTLGLGSGENLNEHVVGRG--WPTVGRRQAMLREAIQIIRDLLC
Mb0415|M.bovis_AF2122/97 CLYPNRVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWS
Rv0407|M.tuberculosis_H37Rv CLYPNRVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWS
MLBr_00269|M.leprae_Br4923 CLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWR
MMAR_0709|M.marinum_M CLYPNRIFLGVGTGEALNEVATGYQGVWPEFKERFARLRESVRLMRELWR
MUL_2814|M.ulcerans_Agy99 CLYPNRIFLGVGTGEALNEVATGYQGVWPEFKERFARLRESVRLMRELWR
* .*. **:*:** *** .* ** . .* * *:: ::* *
MAV_0425|M.avium_104 GQLVDFTGDYFRVDSARVWDVPDVPVGIGVAIGGTRAVDKFAKLADHLIA
MSMEG_1794|M.smegmatis_MC2_155 GELIDFRGEYFEVDSARIWDVPDEPVGIGVSLTGERALEKLAVSTDHLIN
Mflv_1341|M.gilvum_PYR-GCK GEMVDWKGEYFEVDSARLWDVPDVPVRIAAAVSGERSVAQFAPLADHLIA
Mvan_5448|M.vanbaalenii_PYR-1 GDMVDWKGEYFEVDSARLWDVPEVPVPIAAAVSGDRSVEQFALLADHLIA
TH_1712|M.thermoresistible__bu GEVVDWKGEYFEVDSARLWDIPEVPVAIAVAVSGDRSVEMFAPIADHLVT
MAB_0947c|M.abscessus_ATCC_199 GEHVDGKGDYFEVDSARLWDLPDVPVPIGVAVSSGDTAARFAPTADHMIA
Mb0415|M.bovis_AF2122/97 GDRVDFDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFIC
Rv0407|M.tuberculosis_H37Rv GDRVDFDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFIC
MLBr_00269|M.leprae_Br4923 GDRVDFDGDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVC
MMAR_0709|M.marinum_M GDRVDFDGEYYRLRGASIYDVPEGGVPVYIAAGGPAVAKYAGRAGDGFIC
MUL_2814|M.ulcerans_Agy99 GDRVDFDGEYYRLRGASIYDVPEGGVPVYTAAGGPAVAKYAGRAGDGFIC
*: :* *:*:.: .* ::*:*: * : : . . : ::
MAV_0425|M.avium_104 TE-------PNADLVDAWHGARQAANLAGGGRVVGQIPVSWDPDPDTAVK
MSMEG_1794|M.smegmatis_MC2_155 VA-------PDAAVVEGWRKRREATGILPEGRVVGQIPVCWDPDKDAAIA
Mflv_1341|M.gilvum_PYR-GCK VQ-------PDKSIVDAWHETRRGTGLPGDVRVIGQIPICWDPDRDAAID
Mvan_5448|M.vanbaalenii_PYR-1 VE-------PDKDLVDSWHDARHATGLPGEVRVIGQLPICWDTDRDAAID
TH_1712|M.thermoresistible__bu TE-------PDAGLVGSWHHLRRATGLPVETRVFGQVPICWDPDRDAAVE
MAB_0947c|M.abscessus_ATCC_199 VA-------PESDIVDAWRQARRSAAAPEESRVIGQLPICWDTDREAAIK
Mb0415|M.bovis_AF2122/97 TSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALN
Rv0407|M.tuberculosis_H37Rv TSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALN
MLBr_00269|M.leprae_Br4923 TSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALS
MMAR_0709|M.marinum_M TSGKGEELYSEKLMPAVREGAAINNRNIDDIDKMIEIKISYDPDPELALN
MUL_2814|M.ulcerans_Agy99 TSGKGEDLYSEKLMPAVREGAAINNRNIDDIDKMIEIKISYDPDPELALN
. .: : . . :: :.:*.* : *:
MAV_0425|M.avium_104 RAHDQFRWFAGGWKVNADLPTPAGFAGATQFVRPEDVADAIPCGPDLDAI
MSMEG_1794|M.smegmatis_MC2_155 RAHDQFRWFAGGWAVNADLPTPAGFAAATQFVRPEDVASAIPCGPDLDAI
Mflv_1341|M.gilvum_PYR-GCK RAHDQFRWFAGGWAVNADLPTTAGFDGATQFVRKEDVAESIPCGPDLDAI
Mvan_5448|M.vanbaalenii_PYR-1 RAHDQFRWFAGGWAVNSDLPTTAGFDGATQFVRKDDVADSIPCGPDLDAI
TH_1712|M.thermoresistible__bu RAHEQFRWFAGGWAVNSDLPTTAGFAGATQFVRPEDTAAAIACGPDLDAI
MAB_0947c|M.abscessus_ATCC_199 RAHDEFRWFAGGWPVNADLPTPAGFAAATKFVRPEDVAGNIPCGSDSAPS
Mb0415|M.bovis_AF2122/97 -NTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEA
Rv0407|M.tuberculosis_H37Rv -NTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEA
MLBr_00269|M.leprae_Br4923 -NIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEA
MMAR_0709|M.marinum_M -NTRFWAPLSLSAEQKRSIGDPIEMEAAAEALPIEQIAKRWIVASDPDEA
MUL_2814|M.ulcerans_Agy99 -NTRFWAPLSLSAEQKRSIGDPIEMEAAAEALPIEQIAKRWIVASDPDEA
: :: : .: . : .:. : :: * .*
MAV_0425|M.avium_104 VEGVRPYWEAGFTDIALVQIGGDTQERFLKEAAEPLLAALRDAAK-
MSMEG_1794|M.smegmatis_MC2_155 VAAVDEYRQAGFTDIALIQIGGDSQDQFLAEAATPLLAALRESAG-
Mflv_1341|M.gilvum_PYR-GCK VEAVREYWEAGFTDIALVQVGGDTQDQFLAEAATPLLDKLRSASH-
Mvan_5448|M.vanbaalenii_PYR-1 VDAVREYWEAGFTDIALIQVGGDSQEAFLKEAAAPLLDKLRSASH-
TH_1712|M.thermoresistible__bu VEAVRAYWDAGFTDIGLIQIGDENQDLFLEKAAEALLDKLRAAAPR
MAB_0947c|M.abscessus_ATCC_199 SRTRAPTPTPGLP-----------ISRWCRWEAT-----ARTAS--
Mb0415|M.bovis_AF2122/97 VEKVGQYVTWGLNHLVFHAPG-HDQRRFLELFQSDLAPRLRRLG--
Rv0407|M.tuberculosis_H37Rv VEKVGQYVTWGLNHLVFHAPG-HDQRRFLELFQSDLAPRLRRLG--
MLBr_00269|M.leprae_Br4923 VARVGQYVTWGLNHLVFHAPG-HNQRRFLELFEKDLAPRLRRLG--
MMAR_0709|M.marinum_M VEKVGQYVAWGLNHLVLHAPG-HDQLRFLELFEKDLAPRLRRLG--
MUL_2814|M.ulcerans_Agy99 VEKVGQYVAWGLNHLVLHAPG-HDQLRFLELFEKDLAPRLRRLG--
*: : * .