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M. avium 104 MAV_4761 (-)

annotation: F420-dependent glucose-6-phosphate dehydrogenase
coordinates: 4887413 - 4888423
length: 336

AELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGGHAPFSLAWMTAVGERTTRITLG
TSVLTPTFRYNPAVVAQAFATMACLYPGRIFLGVGTGEALNEIATGYQGEWPEFKERFARLRESVRLMRE
LWRGDRVDFDGEYYRLKGASIYDVPDGGVPIYIAAGGPAVAKYAGRAGDGFICTSGKGEELYKDKLIPAV
KEGAAINDRNVDDIDKMIEIKISYDPDPELALENTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQVA
KRWIVASDPDEAVAKVKDYVDWGLNHLVFHAPGHDQRRFLELFEKDLAPRLRRLG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4761--100% (336)F420-dependent glucose-6-phosphate dehydrogenase
M. avium 104MAV_5172-2e-5240.14% (279) F420-dependent glucose-6-phosphate dehydrogenase
M. avium 104MAV_0425-4e-4234.73% (334) dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0415fgd10.090.48% (336) F420-dependent glucose-6-phosphate dehydrogenase
M. gilvum PYR-GCKMflv_0211-1e-18089.29% (336) luciferase family protein
M. tuberculosis H37RvRv0407fgd10.090.48% (336) F420-dependent glucose-6-phosphate dehydrogenase
M. leprae Br4923MLBr_00269-1e-17887.80% (336) putative F420-dependent glucose-6-phosphate dehydrogenase
M. abscessus ATCC 19977MAB_4230c-1e-17386.53% (334) F420-dependent glucose-6-phosphate dehydrogenase
M. marinum MMMAR_0709fgd10.091.07% (336) F420-dependent glucose-6-phosphate dehydrogenase Fgd1
M. smegmatis MC2 155MSMEG_0777-1e-17990.15% (335) F420-dependent glucose-6-phosphate dehydrogenase
M. thermoresistible (build 8)TH_2304-1e-18090.48% (336) PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1
M. ulcerans Agy99MUL_2814fgd10.090.48% (336) F420-dependent glucose-6-phosphate dehydrogenase Fgd1
M. vanbaalenii PYR-1Mvan_0698-0.090.48% (336) luciferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0211|M.gilvum_PYR-GCK          MA-ELKLGYKASAEQFAPRELVELAVAAEEHGMDSATVSDHFQPWRHEGG
Mvan_0698|M.vanbaalenii_PYR-1       MA-ELKLGYKASAEQFAPRELVELAVAAEEHGMDSATVSDHFQPWRHEGG
MAB_4230c|M.abscessus_ATCC_199      MARELKLGYKASAEQFAPRELVELAVATESHGFDSATVSDHFQPWRYNGG
MSMEG_0777|M.smegmatis_MC2_155      MVAELKLGYKASAEQFAPRELVELAVLAESAGMDSATVSDHFQPWRHEGG
TH_2304|M.thermoresistible__bu      -VAELKLGYKASAEQFAPRELVELGVAAEEHGMDSATVSDHFQPWRHKGG
Mb0415|M.bovis_AF2122/97            -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGG
Rv0407|M.tuberculosis_H37Rv         -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGG
MLBr_00269|M.leprae_Br4923          -MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGG
MMAR_0709|M.marinum_M               -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGG
MUL_2814|M.ulcerans_Agy99           -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGG
MAV_4761|M.avium_104                -MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGG
                                       **:******************.* :*  *:*************::**

Mflv_0211|M.gilvum_PYR-GCK          HAPFSLAWMTAVGERTTRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPD
Mvan_0698|M.vanbaalenii_PYR-1       HAPFSLAWMTAVGERTKRLQLGTSVLTPTFRYNPAVIAQAFATMGCLYPG
MAB_4230c|M.abscessus_ATCC_199      HAPFSLAWMTAVGERTQRLQLGTSVLTPTFRYNPAVTAQAFATMGCLYPG
MSMEG_0777|M.smegmatis_MC2_155      HAPFSLAWMTAVGERTKNLVLGTSVLTPTFRYNPAVIAQAFATMGCLYPG
TH_2304|M.thermoresistible__bu      HAPFSLAWMTAVGERTKRITLGTSVLTPTFRYNPAVIAQAFATMACLYPD
Mb0415|M.bovis_AF2122/97            HAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
Rv0407|M.tuberculosis_H37Rv         HAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
MLBr_00269|M.leprae_Br4923          HASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPN
MMAR_0709|M.marinum_M               HAPFSLAWMTAVGERTKRMQLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
MUL_2814|M.ulcerans_Agy99           HAPFSLAWMTAVGERTKRMQLGTSVLTPTFRYNPAVIAQAFATMGCLYPN
MAV_4761|M.avium_104                HAPFSLAWMTAVGERTTRITLGTSVLTPTFRYNPAVVAQAFATMACLYPG
                                    **.***:********* .: **************** .******.****.

Mflv_0211|M.gilvum_PYR-GCK          RIFLGVGTGEALNEIATGYEGEWPEFKERYARLRESVRLMRELWLGDRVD
Mvan_0698|M.vanbaalenii_PYR-1       RIFLGVGTGEALNEIATGYEGDWPEFKERYARLRESVRLMRDLWLGDRVD
MAB_4230c|M.abscessus_ATCC_199      RIFLGVGTGEALNEIATGYIGEWPEFKERFARLRESVRLMRELWTGERVD
MSMEG_0777|M.smegmatis_MC2_155      RIFLGVGTGEALNEIATGYAGEWPEFKERFARLRESVRLMRELWLGDRVD
TH_2304|M.thermoresistible__bu      RIFLGVGTGEALNEIATGYEGEWPEFKERFARLREAVRLMRELWLGDRVD
Mb0415|M.bovis_AF2122/97            RVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVD
Rv0407|M.tuberculosis_H37Rv         RVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVD
MLBr_00269|M.leprae_Br4923          RVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGDRVD
MMAR_0709|M.marinum_M               RIFLGVGTGEALNEVATGYQGVWPEFKERFARLRESVRLMRELWRGDRVD
MUL_2814|M.ulcerans_Agy99           RIFLGVGTGEALNEVATGYQGVWPEFKERFARLRESVRLMRELWRGDRVD
MAV_4761|M.avium_104                RIFLGVGTGEALNEIATGYQGEWPEFKERFARLRESVRLMRELWRGDRVD
                                    *:************:**** * *******:*****:* ***:** *:***

Mflv_0211|M.gilvum_PYR-GCK          FEGEYYKTKGASIYDVPEGGIPIYIAAGGPQVAKYAGRAGDGFICTSGKG
Mvan_0698|M.vanbaalenii_PYR-1       FEGEYYKTKGASIYDVPEGGIPIYIAAGGPQVAKYAGRAGDGFICTSGKG
MAB_4230c|M.abscessus_ATCC_199      FEGEYYRTQGAAIYDVPEGGIPVYIAAGGAVVAKYAGRAGDGFICTSGKG
MSMEG_0777|M.smegmatis_MC2_155      FDGEYYRTKGASIYDVPEGGIPVYIAAGGPVVAKYAGRAGDGFICTSGKG
TH_2304|M.thermoresistible__bu      FDGEYYRTKGASIYDVPEGGVPVYIAAGGPVVAKYAGRAGDGFICTSGKG
Mb0415|M.bovis_AF2122/97            FDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKG
Rv0407|M.tuberculosis_H37Rv         FDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKG
MLBr_00269|M.leprae_Br4923          FDGDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKG
MMAR_0709|M.marinum_M               FDGEYYRLRGASIYDVPEGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKG
MUL_2814|M.ulcerans_Agy99           FDGEYYRLRGASIYDVPEGGVPVYTAAGGPAVAKYAGRAGDGFICTSGKG
MAV_4761|M.avium_104                FDGEYYRLKGASIYDVPDGGVPIYIAAGGPAVAKYAGRAGDGFICTSGKG
                                    *:*:**: :**:*****:**:*:* ****. *********:**:******

Mflv_0211|M.gilvum_PYR-GCK          EELYKEKLIPAMREGAEAAGKNPDDVDRMIEIKISYDTDPELALENTRFW
Mvan_0698|M.vanbaalenii_PYR-1       EELYKDKLIPAMREGAEAAGKNPDDIDRMIEIKISYDTDPELALENTRFW
MAB_4230c|M.abscessus_ATCC_199      EELYSGKLIPAVREGAALAERSFDDIDRMIEIKISYDPDPDKALENTRFW
MSMEG_0777|M.smegmatis_MC2_155      EELYAEKLIPAVKEGAAAADRDADAIDRMIEIKISYDTDPELALENTRFW
TH_2304|M.thermoresistible__bu      AELYQDKLIPAVAEGAAAAGRDADEIDKMIEIKISYDPDPELALENTRFW
Mb0415|M.bovis_AF2122/97            EELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFW
Rv0407|M.tuberculosis_H37Rv         EELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFW
MLBr_00269|M.leprae_Br4923          EELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFW
MMAR_0709|M.marinum_M               EELYSEKLMPAVREGAAINNRNIDDIDKMIEIKISYDPDPELALNNTRFW
MUL_2814|M.ulcerans_Agy99           EDLYSEKLMPAVREGAAINNRNIDDIDKMIEIKISYDPDPELALNNTRFW
MAV_4761|M.avium_104                EELYKDKLIPAVKEGAAINDRNVDDIDKMIEIKISYDPDPELALENTRFW
                                     :**  **:**: ***    :. * :*:*****:***.**: **.* ***

Mflv_0211|M.gilvum_PYR-GCK          APLSLTAEQKHSIDDPMEMEKAADELPIEQVAKRWIVASDPDEAVAKVAD
Mvan_0698|M.vanbaalenii_PYR-1       APLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVAKVKD
MAB_4230c|M.abscessus_ATCC_199      APLSLTPEQKHSIHDPIEMERAADELPIEQVAKRWIVASDPDEAVEKVAD
MSMEG_0777|M.smegmatis_MC2_155      APLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVEKVGQ
TH_2304|M.thermoresistible__bu      APLSLTAEQKHSIDDPIEMERAADELPIEQVAKRWIVASDPDEAVEQVAQ
Mb0415|M.bovis_AF2122/97            APLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQ
Rv0407|M.tuberculosis_H37Rv         APLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQ
MLBr_00269|M.leprae_Br4923          APLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQ
MMAR_0709|M.marinum_M               APLSLSAEQKRSIGDPIEMEAAAEALPIEQIAKRWIVASDPDEAVEKVGQ
MUL_2814|M.ulcerans_Agy99           APLSLSAEQKRSIGDPIEMEAAAEALPIEQIAKRWIVASDPDEAVEKVGQ
MAV_4761|M.avium_104                APLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVAKVKD
                                    *****:.***:** **:*** .*: *****:******.******* :* :

Mflv_0211|M.gilvum_PYR-GCK          YVDYGLNHLVFHAPGHDQRRFLELFQRDLEPRLRKLG
Mvan_0698|M.vanbaalenii_PYR-1       YVDWGLNHLVFHAPGHDQRRFLELFRRDLEPRLRKLG
MAB_4230c|M.abscessus_ATCC_199      YVGWGLNHLVFHAPGHDQKRFLELFKTDLEPRLRKLG
MSMEG_0777|M.smegmatis_MC2_155      YVKWGLNHLVFHAPGHDQRRFLELFKRDLEPRLRKLA
TH_2304|M.thermoresistible__bu      YVKWGLNHLVFHAPGHDQRRFLELFRTDLEPRLRRLG
Mb0415|M.bovis_AF2122/97            YVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
Rv0407|M.tuberculosis_H37Rv         YVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
MLBr_00269|M.leprae_Br4923          YVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG
MMAR_0709|M.marinum_M               YVAWGLNHLVLHAPGHDQLRFLELFEKDLAPRLRRLG
MUL_2814|M.ulcerans_Agy99           YVAWGLNHLVLHAPGHDQLRFLELFEKDLAPRLRRLG
MAV_4761|M.avium_104                YVDWGLNHLVFHAPGHDQRRFLELFEKDLAPRLRRLG
                                    ** :******:*****:* ******. ** ****:*.