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MDERKATGILNAAEQLFLQFGYRKVTIDEVARRAGVGKGTIYLYWPSKLELFGAVFTRDGVAMLTAAADA LRADPREVLLSVSSRRTFIATMNNPLARAIVTGDQALLGDLLTTTPATGEMGLGKLGTTDLVLRLLYRHG LLRDDPEQDPMLAYRVAATTAGFYAVENTSAAGGFALESKADALADTVSSAFEPAEEPSLAVLEAARAEA LTFYERWCHELSAVLNPSAKETAK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4611c | - | - | 100% (235) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 5e-11 | 33.81% (139) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3527 | - | 1e-08 | 38.03% (71) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 4e-08 | 28.48% (151) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2374 | - | 2e-08 | 43.55% (62) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 5e-08 | 28.48% (151) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 1e-07 | 37.84% (74) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0500 | - | 4e-09 | 28.26% (184) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5267 | - | 2e-08 | 40.62% (64) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4983 | - | 6e-09 | 35.92% (103) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1911 | - | 2e-10 | 31.69% (183) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1163 | - | 2e-09 | 28.26% (184) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4272 | - | 9e-10 | 35.29% (102) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3192c|M.bovis_AF2122/97 MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAER
Rv3167c|M.tuberculosis_H37Rv MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAER
Mflv_2374|M.gilvum_PYR-GCK ----MTAE---ISTPRRRSEKSRVAIVDATRGLLLERGFDKLTIEAVAAR
Mvan_4272|M.vanbaalenii_PYR-1 ----MATD---IAAPRRRSEKSRTAIVEATRKLLMERGFDKLTIEAVAAR
MAV_5267|M.avium_104 ----MPTDPNGPAAPRRRSEKSRTAIVTATRELLLERGFDGLTIEAVAAR
MMAR_0500|M.marinum_M ---------MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAA
MUL_1163|M.ulcerans_Agy99 ---------MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAA
MLBr_02568|M.leprae_Br4923 ---------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAE
TH_1911|M.thermoresistible__bu -------------------------MLDAAVQMFSVNGYHETSMDAIAAQ
MSMEG_4983|M.smegmatis_MC2_155 ---------MTGAMGRPRDPSKDVAVLTAVRELLVEEGYQGTTVLAVARR
MAB_4611c|M.abscessus_ATCC_199 ----------------MMDERKATGILNAAEQLFLQFGYRKVTIDEVARR
:: *. :: *: :: :*
Mb3192c|M.bovis_AF2122/97 AGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAG--DIAADIRMMIAA
Rv3167c|M.tuberculosis_H37Rv AGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAG--DIAADIRMMIAA
Mflv_2374|M.gilvum_PYR-GCK AGVGKQTIYRWWPSRHALVADVILEDADRILRPIDHTDDVAADVCAWATG
Mvan_4272|M.vanbaalenii_PYR-1 AGVGKQTIYRWWPSRHALVADVTLEDADRILRPVARTDDVAADLCAWAVT
MAV_5267|M.avium_104 AGVGKQTIYRWWPTRPALVADVMLEDADRLLASVEHSGDLAADLVGWVGK
MMAR_0500|M.marinum_M AQISKPMLYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRN
MUL_1163|M.ulcerans_Agy99 AQISKPMLYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRN
MLBr_02568|M.leprae_Br4923 AQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRN
TH_1911|M.thermoresistible__bu AEISKPMLYLYYGSKEELFGACLKRELSRFVETVRADIDFSQSPKDLLRN
MSMEG_4983|M.smegmatis_MC2_155 AGVGAPTIYRRWPTKEALVEDAAFGHPSPVPMPAPTG-DLRADLREWVAM
MAB_4611c|M.abscessus_ATCC_199 AGVGKGTIYLYWPSKLELFGAVFTRDGVAMLTAAADALRADPREVLLSVS
* :* : :: *.
Mb3192c|M.bovis_AF2122/97 TRDVFTTPV----VRAALP---GLVADMTADAELNARVLARFADLFAAVR
Rv3167c|M.tuberculosis_H37Rv TRDVFTTPV----VRAALP---GLVADMTADAELNARVLARFADLFAAVR
Mflv_2374|M.gilvum_PYR-GCK LAKALTTAR----GNAMLR---ILTAAGMEHPDTAARLQAGFS---VPLH
Mvan_4272|M.vanbaalenii_PYR-1 LATALTTVR----GNAMLR---ALTTAGVEHQDTAARLHAGFN---QPIH
MAV_5267|M.avium_104 LVTSLTTPR----GSAMLR---TLTVACMEHEDTAVKLRAGFS---APLH
MMAR_0500|M.marinum_M AIVSFLRYID--QNQASWI---VMYTQAVSSQAFAQTVREGREQIVELVA
MUL_1163|M.ulcerans_Agy99 AIVSFLRYID--QNQASWI---VMYTQAVSSQAFAQTVREGREQIVELVA
MLBr_02568|M.leprae_Br4923 TIVSFLRYID--ANRASWI---VMYIQAMSLPAFAQTVREARDQITELVA
TH_1911|M.thermoresistible__bu AVRSFLTYID--TNRASWL---VLYTQATSSQAFAHTVREGRERIIDLVA
MSMEG_4983|M.smegmatis_MC2_155 FLDWLAQPV----TRAALP---GLITAYHHDETLYERLVLRSETDVRAAM
MAB_4611c|M.abscessus_ATCC_199 SRRTFIATMNNPLARAIVTGDQALLGDLLTTTPATGEMGLGKLGTTDLVL
: * : :
Mb3192c|M.bovis_AF2122/97 MRLREA--VDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWVDQ
Rv3167c|M.tuberculosis_H37Rv MRLREA--VDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWVDQ
Mflv_2374|M.gilvum_PYR-GCK DTVRNR--LAASGFTDRAVQDGADAIVGG--IVYAILNEGRAFESRRAES
Mvan_4272|M.vanbaalenii_PYR-1 DAVRGR--LTAEGLTAESARDATDAIVGG--IVYAILSEGRSFDPHRAES
MAV_5267|M.avium_104 DSVRAR--LLAEGVDAATAESAADAIVGG--VVYPILSGAQRYSRRRAEH
MMAR_0500|M.marinum_M GMLRAG--TRSPRSDAEID-MMAAALVGAGEAVANRLSAGDTDVDEAAEM
MUL_1163|M.ulcerans_Agy99 GMLRAG--TRSPRSDAEID-MMAAALVGAGEAVANRLSAGDTDVDEAAEM
MLBr_02568|M.leprae_Br4923 GLMRVG--TRSSRPDHEYE-IMAGALVGAGEAMATRLTTGDIAVDEAAEL
TH_1911|M.thermoresistible__bu RLLRSG--TRHPEPDTDFD-MMAVALVGAGEAVATRVSAGDAEVDEAAEL
MSMEG_4983|M.smegmatis_MC2_155 VDLLDG--DRR-RADAVFDFLVATTVVRA---MTRGLTDRDAFCDRTADA
MAB_4611c|M.abscessus_ATCC_199 RLLYRHGLLRDDPEQDPMLAYRVAATTAGFYAVENTSAAGGFALESKADA
: . : .:
Mb3192c|M.bovis_AF2122/97 TTAIVVRGVHRAAPGGSVV-------------------------------
Rv3167c|M.tuberculosis_H37Rv TTAIVVRGVHRAAPGGSVV-------------------------------
Mflv_2374|M.gilvum_PYR-GCK ISRAVLAGISAR--------------------------------------
Mvan_4272|M.vanbaalenii_PYR-1 ITRTVIAGITTR--------------------------------------
MAV_5267|M.avium_104 TTRLIVAALTAG--------------------------------------
MMAR_0500|M.marinum_M MIDLFWRGLKGAPSD------REIGSNFAAG-------------------
MUL_1163|M.ulcerans_Agy99 MIDLLWRGLKGAPSD------REIGSNFAAG-------------------
MLBr_02568|M.leprae_Br4923 MINLFWHGLKGAPAD------RDFGPSIVAG-------------------
TH_1911|M.thermoresistible__bu LINLFWRGLKGTPAESHEDTHRENGQDVDRDGVDQSTTV-----------
MSMEG_4983|M.smegmatis_MC2_155 LFALARSDHL----------------------------------------
MAB_4611c|M.abscessus_ATCC_199 LADTVSSAFEPAEEPSLAVLEAARAEALTFYERWCHELSAVLNPSAKETA
Mb3192c|M.bovis_AF2122/97 -
Rv3167c|M.tuberculosis_H37Rv -
Mflv_2374|M.gilvum_PYR-GCK -
Mvan_4272|M.vanbaalenii_PYR-1 -
MAV_5267|M.avium_104 -
MMAR_0500|M.marinum_M -
MUL_1163|M.ulcerans_Agy99 -
MLBr_02568|M.leprae_Br4923 -
TH_1911|M.thermoresistible__bu -
MSMEG_4983|M.smegmatis_MC2_155 -
MAB_4611c|M.abscessus_ATCC_199 K