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ARIPLADPATLSGLEQAVYQRFPANLVLGLLRATPEIADGYLDLGGALSASPLDRGIREMVILRVGTLSG SAYERMQHLGIARSVGLSDAEIAAVDSGRFDELAPNERAILSFVDELVASPKATVTFDAALRALGEQGLA TVILLVGHYMLTARLLETLEIDLDAGPTSWDGI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4488c | - | - | 100% (174) | carboxymuconolactone decarboxylase |
| M. abscessus ATCC 19977 | MAB_2021c | - | 6e-15 | 35.00% (160) | putative carboxymuconolactone decarboxylase |
| M. abscessus ATCC 19977 | MAB_2040c | - | 2e-12 | 30.68% (176) | hypothetical protein MAB_2040c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 3e-11 | 28.02% (182) | hypothetical protein Mb1558 |
| M. gilvum PYR-GCK | Mflv_2440 | - | 7e-10 | 31.65% (158) | carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv1531 | - | 3e-11 | 28.02% (182) | hypothetical protein Rv1531 |
| M. leprae Br4923 | MLBr_02465 | - | 2e-06 | 32.31% (130) | hypothetical protein MLBr_02465 |
| M. marinum M | MMAR_3164 | - | 5e-11 | 30.77% (169) | hypothetical protein MMAR_3164 |
| M. avium 104 | MAV_2165 | pcaC | 2e-15 | 32.35% (170) | hypothetical protein MAV_2165 |
| M. smegmatis MC2 155 | MSMEG_0905 | pcaC | 1e-09 | 36.89% (122) | hypothetical protein MSMEG_0905 |
| M. thermoresistible (build 8) | TH_2018 | - | 2e-09 | 31.72% (145) | carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 9e-05 | 30.23% (129) | hypothetical protein MUL_4533 |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 1e-11 | 32.56% (129) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 MSGTQSAESDDDADDSEGDASADDAEDAEEFVGDSGNGGSDDDAADDSEK
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQPASTESTEQSADVANDA
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 DGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVEPMGPLINSLWWAV
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 PKSGGRSTNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADGTEQNPNG
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 VGGGWLFGDGGDGWSSTLAGIAGGKGGAAGLLWGSGGDGGAGGAGAAGGT
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GGNAGLLWGNGGHGGAGGAGVNGAVGTSGVNNGRGGDGTAGGSGGAGGNA
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GLLSGRGGDGGVGGAGGKGGAGAHGSDAVAAEEDGGPGGSGGAGGNAGAG
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GVGGRGALLFGRGGDGGDGGSAGTGGAGGFGGTGGAIVVTLPGGKLSDSD
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GAGGAGGVGGAAGLGGDGGGGGLGGLLGQAGVNGDSGATAAAGNAGGVGG
Mb1558|M.bovis_AF2122/97 ----------------MT-TSRVPLLPVDEAKAAADEAGVPDYMAELSIF
Rv1531|M.tuberculosis_H37Rv ----------------MT-TSRVPLLPVDEAKAAADEAGVPDYMAELSIF
MMAR_3164|M.marinum_M ----------------MTRTERVPMLDLEQARLRAAECGLPAEMAELSVF
MAB_4488c|M.abscessus_ATCC_199 -------------------MARIPLA--DPATLSGLEQAVYQRFPANLVL
MAV_2165|M.avium_104 -------------------MTRIPYR--RPEEMPARARELTARRGNLNVY
Mflv_2440|M.gilvum_PYR-GCK -------------MRVAPLPADQWDDTVDKALSGLMPEEMRNPETAGNLV
TH_2018|M.thermoresistible__bu -------------VRLAPLPAEQWDDEVLSALAVMLPEERRNPDGAGTAL
MLBr_02465|M.leprae_Br4923 ---MSGGTGTGPVGRIPPG-SLRQLGPINWVIAKLAASLLRTSEMH--LF
MUL_4533|M.ulcerans_Agy99 ---MTG----DQVARIPSG-GIRQLGPVNWALAKLAARSVRAPEMH--LF
MSMEG_0905|M.smegmatis_MC2_155 ---MTR-DHQTEPARIPATRSLRALGPIGWIAARAGARAIRAPRFH--LF
Mvan_0928|M.vanbaalenii_PYR-1 AGGLGGRLPIVDLNNASPAQATLAALIKKLGLPIQAATGIQLEDVDGRLV
Mb1558|M.bovis_AF2122/97 QVLLN--HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEW
Rv1531|M.tuberculosis_H37Rv QVLLN--HPRLARTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEW
MMAR_3164|M.marinum_M RVALH--QPSLAVALYGMLEALLFNGVLDARLRELIIMRIGWVTGSVYEW
MAB_4488c|M.abscessus_ATCC_199 GLLRA--TPEIADGYLDLG-GALSASPLDRGIREMVILRVGTLSGSAYER
MAV_2165|M.avium_104 RALAN--AEKVFTSWMVAGDAALSSPVLPRRLRELIVLRTASAMDCAYEL
Mflv_2440|M.gilvum_PYR-GCK ATLVR--HPRLAKGFLRFNFHLLYGSSLPARLRELAVLRIAHLTKCEYEW
TH_2018|M.thermoresistible__bu STLVR--HPRLTKAFLRFSNHLLFRSTLPPRLRELAVLRVAHRRSCDYEW
MLBr_02465|M.leprae_Br4923 TILGQ--RQLLFWAWLIYGGRLL-RGKLPRVDTELVILRVAHLRTCEYEL
MUL_4533|M.ulcerans_Agy99 TALGY--RQYLFWTWAIYSGRLL-HGRLPRIDTELVILRVAHLRSCEYEL
MSMEG_0905|M.smegmatis_MC2_155 DVIGQ--HKLAFLAFLPYSGVLLNWGKLPKRDTELVILRVAHLRGSTYEL
Mvan_0928|M.vanbaalenii_PYR-1 GPLNAYLYNTIIGKAIFDVGNTFSSASLSARVKEIVILSVGGQWGSEYEL
: * *: :: . . **
Mb1558|M.bovis_AF2122/97 TQHWRVASGLGVSADDLLGVRDWQG-------YNGFGPAEQAVLAATDDV
Rv1531|M.tuberculosis_H37Rv TQHWRVASGLGVSADDLLGVRDWQG-------YNGFGPAEQAVLAATDDV
MMAR_3164|M.marinum_M TQHWRIATLLGVASDDLLAVRDWQS-------SNRLGHAERAVLAATDDV
MAB_4488c|M.abscessus_ATCC_199 MQHLGIARSVGLSDAEIAAVDSGR--------FDELAPNERAILSFVDEL
MAV_2165|M.avium_104 GQHRDVARTVGIDPATIDAVISETGWQ-----ASDLTPTELAALHLTTEL
Mflv_2440|M.gilvum_PYR-GCK LHHVEMGREAGLSDDVIDGITRGEAT----------DGLDRAVLNAVDEL
TH_2018|M.thermoresistible__bu AHHVFIGKAEGLTDDDIAGVQRGAVD----------DPFDQAVLDAVDEL
MLBr_02465|M.leprae_Br4923 QHHRRMARKRGLDTKIQAMIFAWPDVPTGAG----LSVRQQALLAATDEF
MUL_4533|M.ulcerans_Agy99 QHHRRMARAAGLDAHAQATIFAWPDAPQGDGPRRVLSSRQQALLTATDEL
MSMEG_0905|M.smegmatis_MC2_155 QQHRRLARSRGLDTETQAKIFEGPDA---EG----LTDRQRTLITATDEF
Mvan_0928|M.vanbaalenii_PYR-1 YAHKLAAQLFGIPADAIAALANGQAP-------VGLSGNELLAAQFVQEL
* . *: : : . :.
Mb1558|M.bovis_AF2122/97 VREGAVSAQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLE
Rv1531|M.tuberculosis_H37Rv VREGAVSAQSWSACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLE
MMAR_3164|M.marinum_M VRDGVIAEENWAACHKAFNGDHAVLVELVGAIANWRLFSILLRSLNIPLE
MAB_4488c|M.abscessus_ATCC_199 VASP-KATVTFDAALRALGEQ--GLATVILLVGHYMLTARLLETLEIDLD
MAV_2165|M.avium_104 VTTRRVAQPLFDRVHRALGTE--ATVEALMVINRYAGLALMLNALEVDLD
Mflv_2440|M.gilvum_PYR-GCK QNDSVVSDATWTALSDHLDER--QLMDLVFTIGCYGALAMAINTFGVEPD
TH_2018|M.thermoresistible__bu EEHYRISDATWATLGARLDER--QLMDLVFTVGCYGLMAMAYNTFGITPE
MLBr_02465|M.leprae_Br4923 VKDRKITSSSWQQLETHLDRR--RLIEFCMLISQYDGLAATISSLDIPLD
MUL_4533|M.ulcerans_Agy99 IKNRSVTPATWEQLEIHLNRR--RLIEFCLLATQYDALAATITALGVPLD
MSMEG_0905|M.smegmatis_MC2_155 VVTRSMSPETWAALSTHLNRA--QLIEFCLLAGHYDGLAATMATLRIPLD
Mvan_0928|M.vanbaalenii_PYR-1 VSTRRVSDALFEAAEAAFGQT--GVVDMVNLAGTYLGVSATLNAFKVRGP
: : : : : :: :
Mb1558|M.bovis_AF2122/97 DGVSSWPPDGLSPR------------------------------------
Rv1531|M.tuberculosis_H37Rv DGVSSWPPDGLSPR------------------------------------
MMAR_3164|M.marinum_M SGTDSWPPDGRAPRRDD---------------------------------
MAB_4488c|M.abscessus_ATCC_199 AGPTSWDGI-----------------------------------------
MAV_2165|M.avium_104 ETARLPIPPTS---------------------------------------
Mflv_2440|M.gilvum_PYR-GCK QER-----------------------------------------------
TH_2018|M.thermoresistible__bu TGR-----------------------------------------------
MLBr_02465|M.leprae_Br4923 NSC-----------------------------------------------
MUL_4533|M.ulcerans_Agy99 NPR-----------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 FPD-----------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ESFSAPVLPAAPSPVPASDEYGLGGRLPLIDLDTATPAQLDLAAKIKALA
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 VPTQQATGIELVSPDGRLIGPLNGYLYNPVIGQALFEVGNAFASSSLSSR
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 IKEIVILSVGGQWGSGYEVYAHEKVARLVGIPEEAIVSLASGHAPVGLSG
Mb1558|M.bovis_AF2122/97 --------------------------------------------------
Rv1531|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3164|M.marinum_M --------------------------------------------------
MAB_4488c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2165|M.avium_104 --------------------------------------------------
Mflv_2440|M.gilvum_PYR-GCK --------------------------------------------------
TH_2018|M.thermoresistible__bu --------------------------------------------------
MLBr_02465|M.leprae_Br4923 --------------------------------------------------
MUL_4533|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0905|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 SELVAARFVQELVSTYEVSSELYHSAEAAFGQAGLVDLVNLASTYLGASA
Mb1558|M.bovis_AF2122/97 ------------------
Rv1531|M.tuberculosis_H37Rv ------------------
MMAR_3164|M.marinum_M ------------------
MAB_4488c|M.abscessus_ATCC_199 ------------------
MAV_2165|M.avium_104 ------------------
Mflv_2440|M.gilvum_PYR-GCK ------------------
TH_2018|M.thermoresistible__bu ------------------
MLBr_02465|M.leprae_Br4923 ------------------
MUL_4533|M.ulcerans_Agy99 ------------------
MSMEG_0905|M.smegmatis_MC2_155 ------------------
Mvan_0928|M.vanbaalenii_PYR-1 LLNVFEVPVPTAALITTS