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AKHAKLVVLAWLAVGVLVNTAWPQLERVANEHSVSPLPTGEVSPALASMKEMGKAFGRPGIDNAVIIVMH GDKGFDADAQARYSALIERLRGNTEYVTFVQDQLGDPRMRNNPVARKQVLSEDGTTWYAMAGLAGDLGTP LAQRAFRSVDDLVKQTFAGSATTANITGAAGTVTDMGNAALGDLPKIGAVTVVVIGLILLLVFRSWFTAM LPLLVMGVSLLIARGVIAGLAERGLVPVSSVSAGLMMAVLMGASVNYTVFLVSRYHERIRAGESPPDALA HACGSMTRVILATAATVAIANIAQLTARLAFLAAAGPAVSMGVIVAFFVVTTMLPATLSLAAKRGLGLPG SDRVDVYWHRMGVNIVRHPWPFFGVATVILLAAASFVPFMRPSFDISKVLPESAQSNQGMRTLNAHFPAN SIMPQYLLVQASSDLRNPRALADLDQMAERISQLKGVGKVVGITRPDGNKLTQATLAWQIGYMGTQIDKT SGQVNADLRPQLERMSKLADVMSAMTNELGDGDPARLQQMMPQTLAMAKELEGQLDRYQSLISQMGTVAG MVDQLATMGPSVEATFTALDAGASLAQTLAESPFCPVQPDCVTLRDQLVELRTTGPLSSVESLRESVRAV TGGKTITQLLGDMNSQFKQIRGLLAKLPEMERKFERIAGYFQQLQGLGVDLNSVKNMGVRIRDLNTQLED TVRSMGEAAATLQGIGKNSNSAAASGFSVPGAMLQNPGFKELSAAFLQDDGRTAMYMIQSPLNPYGPEAM QLSRDMERVGNEATPNTALAGAKVSVGGFPAINADLKKAYDSDLREIIVVTLLIIFLVMCLLLRAVVAPL YLLGTVLLTYIASLGIGVLVFQVLLGQQLDWAVPAMTFVLIVAVGADYNMLFISRLREESARNMRVGIIR TVRQTGSVITSAGLVFAASLLGMMVGSVNQMVQMGFIIGVGILLDTFVVRTLMVPTLAQAFGKLSWWPSK A*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4240c | - | - | 100% (982) | putative membrane protein, MmpL |
| M. abscessus ATCC 19977 | MAB_0855 | - | 0.0 | 36.02% (994) | MmpL family protein |
| M. abscessus ATCC 19977 | MAB_0937c | - | e-176 | 36.77% (998) | MmpL family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1215 | mmpL10 | 0.0 | 36.42% (994) | transmembrane transport protein MmpL10 |
| M. gilvum PYR-GCK | Mflv_0403 | - | 1e-178 | 36.90% (1008) | transport protein |
| M. tuberculosis H37Rv | Rv1183 | mmpL10 | 0.0 | 36.42% (994) | transmembrane transport protein MmpL10 |
| M. leprae Br4923 | MLBr_01231 | mmpL10 | 1e-173 | 34.97% (998) | hypothetical protein MLBr_01231 |
| M. marinum M | MMAR_4836 | - | 0.0 | 39.70% (990) | MmpL family transport protein |
| M. avium 104 | MAV_1761 | - | 1e-169 | 35.63% (1002) | MmpL10 protein |
| M. smegmatis MC2 155 | MSMEG_4741 | - | 1e-174 | 35.54% (996) | MmpL protein |
| M. thermoresistible (build 8) | TH_3450 | - | 0.0 | 40.35% (984) | PUTATIVE MMPL domain protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-109 | 28.83% (978) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_2900 | - | 0.0 | 41.21% (990) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4836|M.marinum_M MADYGWVSSGVATLSRPVRERLQKVAAGEGAYSDRLARLAGFSIRHKVLI
TH_3450|M.thermoresistible__bu -----------------------------------------------VLV
Mvan_2900|M.vanbaalenii_PYR-1 -----------MVLTATVEARNRRVPERTGEFSPRLAALGRFTLRHKALV
MAB_4240c|M.abscessus_ATCC_199 ------------------------------------------MAKHAKLV
Mb1215|M.bovis_AF2122/97 -------------------------------------------------M
Rv1183|M.tuberculosis_H37Rv -------------------------------------------------M
MLBr_01231|M.leprae_Br4923 ------------------------------------------------MV
Mflv_0403|M.gilvum_PYR-GCK -----------------------------------MRRLADVVVRWPWAV
MAV_1761|M.avium_104 -----------------------MSPTAPAGDEVEMRRIADFVVRWPWLV
MSMEG_4741|M.smegmatis_MC2_155 ------------------------------MSRVGFSGLGRFIVRHPLVV
MUL_0757|M.ulcerans_Agy99 ---------------MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPL
:
MMAR_4836|M.marinum_M IGMWVVTAAALAVLFPQLETVVRQQSVNLIPR--DAPSLQTVDRMGAAFG
TH_3450|M.thermoresistible__bu IGTWLAVAVVLALLFPQLETVVRQQSVDLIPR--DVPSFQTLDRMSAAFG
Mvan_2900|M.vanbaalenii_PYR-1 IGAWLGVAVILAVVFPQLETVVRQQSVQLLPN--DVASFIAVEEMAAAFD
MAB_4240c|M.abscessus_ATCC_199 VLAWLAVGVLVNTAWPQLERVANEHSVSPLPTGEVSPALASMKEMGKAFG
Mb1215|M.bovis_AF2122/97 VGCWVALALVLPMAVPSLAEMAQRHPVAVLPA--DAPSSVAVRQMAEAFH
Rv1183|M.tuberculosis_H37Rv VGCWVALALVLPMAVPSLAEMAQRHPVAVLPA--DAPSSVAVRQMAEAFH
MLBr_01231|M.leprae_Br4923 IGCWTLLALMLPMTVPSLTELTQRHPVVILPV--DAPSSVAAKKISQAFH
Mflv_0403|M.gilvum_PYR-GCK IGVWIALAVALPLSFPSLGQMAAKNPLQILPA--DAPSSVTAQKMAEAFD
MAV_1761|M.avium_104 IGFWAALAVALPLAFPSLAEMAQKHPLAILPG--NAPSNVAARQMTEAFH
MSMEG_4741|M.smegmatis_MC2_155 IASWLAVAGVLLAAVPSLPAVAERNPPGFLPA--DSEVFAAGNAMQEAFN
MUL_0757|M.ulcerans_Agy99 ILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPD--AAPSMISMKHIGKVFR
: * : *.* : :. * : : .*
MMAR_4836|M.marinum_M EQGSKTTIFVAMEDPAGLTAPVRQRYNTMISRLRADSEHVRLVQDLLADP
TH_3450|M.thermoresistible__bu EQGSKTTVFVAMEDPAGLTPAARDRYEAMVSRLRADTDHVLLVQDLLADP
Mvan_2900|M.vanbaalenii_PYR-1 EHGAKTSIVVAMEDPAGLTPQTRQRYDALVAALRADATNVLLVQDFLSDP
MAB_4240c|M.abscessus_ATCC_199 RPGIDNAVIIVMHGDKGFDADAQARYSALIERLRGNTEYVTFVQDQLGDP
Mb1215|M.bovis_AF2122/97 ESGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTP
Rv1183|M.tuberculosis_H37Rv ESGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTP
MLBr_01231|M.leprae_Br4923 EVDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTP
Mflv_0403|M.gilvum_PYR-GCK EPGSDNLLVVAFINESGLVPEDELTYRNVVDALRDDVADVVSVQDFLGTP
MAV_1761|M.avium_104 ESGSDDLLLVALTDEKGLGPADEAVYRRLVDALRRDTRDVVMVQDFISAP
MSMEG_4741|M.smegmatis_MC2_155 ETGGGNVAIAILSNENGLTPADEETYRALVDKLRADTEYVLSTQDFVTIP
MUL_0757|M.ulcerans_Agy99 EGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDP
. . . : . : . . * :: ** : * ** *
MMAR_4836|M.marinum_M ------VTASQAVSQDGKAWYVPVGVAGTLGDVKAAESVQAVRTIAAQ--
TH_3450|M.thermoresistible__bu ------VTATQAVSQDGKAWYLPVGVAGTLGDPTAAESVQAVRALAAE--
Mvan_2900|M.vanbaalenii_PYR-1 ------TTRSQVVSEDGKAWFLPVGIVGTLGDPQAAASVEAVRASADS--
MAB_4240c|M.abscessus_ATCC_199 RMRNNPVARKQVLSEDGTTWYAMAGLAGDLGTPLAQRAFRSVDDLVKQ--
Mb1215|M.bovis_AF2122/97 ------PLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKR--
Rv1183|M.tuberculosis_H37Rv ------PLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKR--
MLBr_01231|M.leprae_Br4923 ------PLHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQT-
Mflv_0403|M.gilvum_PYR-GCK ------QLRQFLTSEDKTTWVLPVSLVGELGTPRAYESFNRVADVIRH--
MAV_1761|M.avium_104 ------PLRSAVTSKDRKAWVLPVGIAGELGTPQSYAAFNRIAGIVKQTL
MSMEG_4741|M.smegmatis_MC2_155 ------ELRQVMTSEDNKAWQLPISAAGTMGTAEGQNAYRQIVDTVKS--
MUL_0757|M.ulcerans_Agy99 ------LTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDS--
* * .: .* * . : :
MMAR_4836|M.marinum_M -----AFSGSPTNVRVTGPPATFHDQIASAEEDLVVISIATAGLIAMILL
TH_3450|M.thermoresistible__bu -----AFADSSTTVRVTGPPATFSDQIGSAEHDLVLISIATAGLIALILL
Mvan_2900|M.vanbaalenii_PYR-1 -----AFAGSSSTVHVTGPAATFHDQIATAEHDALLVKVASAALIAIILL
MAB_4240c|M.abscessus_ATCC_199 -----TFAGSATTANITGAAGTVTDMGNAALGDLPKIGAVTVVVIGLILL
Mb1215|M.bovis_AF2122/97 -----TVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILM
Rv1183|M.tuberculosis_H37Rv -----TVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILM
MLBr_01231|M.leprae_Br4923 ---LESTAGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILM
Mflv_0403|M.gilvum_PYR-GCK EVPDAGTGGSSLTVHVTGPAATVADLTVAGEQDRLPIEIAIAVLVLGVLL
MAV_1761|M.avium_104 EKHENGPAATSLTVSLTGPAATVADLTVAGERDRLPIELAIAVLVLVVLL
MSMEG_4741|M.smegmatis_MC2_155 -----STANTSLSAEVIGPAATFEDVVKIGERDQHVIEIATVLIVLMILI
MUL_0757|M.ulcerans_Agy99 -----LQAPPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLL
. . .. : *... . * . . : . :: :*:
MMAR_4836|M.marinum_M VVYRSVFTALLPLLVIGVSLAVGRGVLSALGESG-MPVSQFTIAFMTVIL
TH_3450|M.thermoresistible__bu IVYRSVFTALLPLLVIGVSLAVGRGVLSALGEMG-MPVSQFTVAFMTAIL
Mvan_2900|M.vanbaalenii_PYR-1 LVYRSVVTALLPLLVVGVSVAVARGVLSGLGEAG-MPVSQFTVIFLVGIL
MAB_4240c|M.abscessus_ATCC_199 LVFRSWFTAMLPLLVMGVSLLIARGVIAGLAERGLVPVSSVSAGLMMAVL
Mb1215|M.bovis_AF2122/97 VIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMI
Rv1183|M.tuberculosis_H37Rv VIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMI
MLBr_01231|M.leprae_Br4923 IIYRNPITMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMI
Mflv_0403|M.gilvum_PYR-GCK LVYRNPVTMLLPLLTIGASVLIAQGVVAGYSELTGAGVSNQSIVFLSAIL
MAV_1761|M.avium_104 VVYRSAVTMLLPLVTILLSLVIAQAAVAGYSQLTGSGVSNQSIVFLSAIM
MSMEG_4741|M.smegmatis_MC2_155 IVYRNLVAMLLPLLMIGMALVVAEQSVAGLGAIHLIGLGPQTLMLMTAMM
MUL_0757|M.ulcerans_Agy99 LVYRSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLA
:::*. .: : * : .: . :: . :. :: :
MMAR_4836|M.marinum_M LGAGTDYSVFLISRYHEQRRQN----VPPDLSVINATATIGRVILASAAT
TH_3450|M.thermoresistible__bu LGAGTDYTVFLISRYHEQRRAQ----VAPEQAAIYATASIGRVILASAAT
Mvan_2900|M.vanbaalenii_PYR-1 LGAGTDYSVFFISRYHEQRRLG----TDPEEAIIYACGSIGRVILASAAT
MAB_4240c|M.abscessus_ATCC_199 MGASVNYTVFLVSRYHERIRAG----ESPPDALAHACGSMTRVILATAAT
Mb1215|M.bovis_AF2122/97 AGAGTDYAVFLISRYHEYVRLG----EHPERAVQRAMMSVGKVIAASAAT
Rv1183|M.tuberculosis_H37Rv AGAGTDYAVFLISRYHEYVRLG----EHPERAVQRAMMSVGKVIAASAAT
MLBr_01231|M.leprae_Br4923 AGAGTDYAVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAAT
Mflv_0403|M.gilvum_PYR-GCK AGAGTDYAVFLISRYHDYLRRG----AEAGEAVRAAMASIGKVITASAST
MAV_1761|M.avium_104 AGAGTDYAVFLISRYHDFLRRG----DDFDQAVRKALISIGKVITASAST
MSMEG_4741|M.smegmatis_MC2_155 MGAGTDYAIFLFSRYHECVRSG----LSSDDAVVEALDSIGKVIAGSAGT
MUL_0757|M.ulcerans_Agy99 IAAATDYAIFLIGRYQEARGLG----QDRESAYYTMFGGTAHVVLGSGLT
.*..:*::*:..**:: : :*: .:. *
MMAR_4836|M.marinum_M VAFAFLAMVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRG-
TH_3450|M.thermoresistible__bu VAFAFLAMVFARLSVFAALGPACAIAVLFGFLATVTLLPPVLALAAKRG-
Mvan_2900|M.vanbaalenii_PYR-1 VALALASMVFARLSVFQGVGPACAIAVLIGFLATVTLLPPVMALAAKRG-
MAB_4240c|M.abscessus_ATCC_199 VAIANIAQLTARLAFLAAAGPAVSMGVIVAFFVVTTMLPATLSLAAKRG-
Mb1215|M.bovis_AF2122/97 VGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG-
Rv1183|M.tuberculosis_H37Rv VGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG-
MLBr_01231|M.leprae_Br4923 VGITFLGMSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRG-
Mflv_0403|M.gilvum_PYR-GCK VGITFLAMSFAEMGVFRTIGVSAAIGIGVAYLAGVTLLPAILVLAGPRG-
MAV_1761|M.avium_104 VGITFLLIGFARMGVFKTVGISSAIGIGVAFLAAVTLLPAIMVLAGPRG-
MSMEG_4741|M.smegmatis_MC2_155 VAITFMGLAFTDLGVFSTVGPALSVTIGFGFVASVTLLPAMVVLAGRRG-
MUL_0757|M.ulcerans_Agy99 IAGATFCLSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGK
:. : : : : * . :: : . . *: *. : : . *
MMAR_4836|M.marinum_M IGEPKADRTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYD
TH_3450|M.thermoresistible__bu IGDPKPDRTRRYWNSVAVAVVRRPVTLLTISLAVLLALSAVAVTINISYD
Mvan_2900|M.vanbaalenii_PYR-1 IAEPRADLSRRYWNRIAVTVVRRPKPLLAGSLVVLLALTGVAATMTISYD
MAB_4240c|M.abscessus_ATCC_199 LGLPGSDRVDVYWHRMGVNIVRHPWPFFGVATVILLAAASFVPFMRPSFD
Mb1215|M.bovis_AF2122/97 WVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYD
Rv1183|M.tuberculosis_H37Rv WVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYD
MLBr_01231|M.leprae_Br4923 WVAPRRDRAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYD
Mflv_0403|M.gilvum_PYR-GCK WIKPRRELTAQFWRRSGIRIVRRPVPHLVASALVLALLAGFAIVADFNYD
MAV_1761|M.avium_104 WIRPRRELTTGLWRRSGIRIVRRPRAHLVASVLVLIILASCAGLVRYNYD
MSMEG_4741|M.smegmatis_MC2_155 WVKPRKDLTGRIWRRSGVHIVRKPVIHLVASLTVLLALAGCAMLVNFNYD
MUL_0757|M.ulcerans_Agy99 LLEPKRMARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYN
* *. . :** * : : .::
MMAR_4836|M.marinum_M DRRGQPATTASNEGYRLLDRHFRKDAIVTEFMVVESPTDMRTSKALADLD
TH_3450|M.thermoresistible__bu DRKGQPADTASNQGYQLLDRHFRKDVVFTEFLVVENPTDMRTGKGLADLD
Mvan_2900|M.vanbaalenii_PYR-1 DRQGQPAATDSNQGYKLLDRHFAKDSVITQFLLVQSDTDMRTAKALADLD
MAB_4240c|M.abscessus_ATCC_199 ISKVLPESAQSNQGMRTLNAHFPANSIMPQYLLVQASSDLRNPRALADLD
Mb1215|M.bovis_AF2122/97 DRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLE
Rv1183|M.tuberculosis_H37Rv DRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLE
MLBr_01231|M.leprae_Br4923 DRKQIPASDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMA
Mflv_0403|M.gilvum_PYR-GCK DRKAVDAAAPSSVGYAALERHFPISQSIPQYILIQSPKDLRNPQALADLE
MAV_1761|M.avium_104 DRKALRPSAPSSVGYAALERHFPVNQSIPEYILIRSPHDLRTPQALADLE
MSMEG_4741|M.smegmatis_MC2_155 DRKNLPDDAHSNMGYAALDKHFPVSSTVQQFILIQSPHDLRSPKALADME
MUL_0757|M.ulcerans_Agy99 DRNYLPADLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVIN
. :. * : ** : :::. *:*. : :
MMAR_4836|M.marinum_M EMASRVSQLPGVTKVSGVTRPTGARLDQAQLSWQNGEIG---DKMAGAV-
TH_3450|M.thermoresistible__bu EMASRVAQIPGVTKVSGVTRPTGERLDQAKLAWQNQQIG---DKMADAV-
Mvan_2900|M.vanbaalenii_PYR-1 QLASRIAQMPGITRVSGVTRPTGDRLEQAQLSWQNGQIG---DKMAGAV-
MAB_4240c|M.abscessus_ATCC_199 QMAERISQLKGVGKVVGITRPDGNKLTQATLAWQIGYMGTQIDKTSGQVN
Mb1215|M.bovis_AF2122/97 QLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVG---NRLGGAS-
Rv1183|M.tuberculosis_H37Rv QLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVG---NRLGGAS-
MLBr_01231|M.leprae_Br4923 ELAQRVSQIPGIALVRGVTRPTGKPLEETSATYQAGMVG---KQLGSAS-
Mflv_0403|M.gilvum_PYR-GCK QMASRIAQLPDVSLVSGVTRPLGEVPAEFRATFQAGIVG---DRLAAGS-
MAV_1761|M.avium_104 QLADRVSQLPNVSVVSGITRPTGNVPEQFRATYQAGAIG---SMLAGGS-
MSMEG_4741|M.smegmatis_MC2_155 QMAQRVSQLPDIEMVRGVTRPTGEMLQEARATWQAGEVG---GKLNDAS-
MUL_0757|M.ulcerans_Agy99 KIAKAIFGVEGISRVQAITRPDGKPIEHTSIPFLISMQG-----------
::*. : : .: * .:*** * . .: *
MMAR_4836|M.marinum_M AKGDAHKDDLAKLTHGADQLAGGLAQLDTTLRTALTPLTGLLTQAQSSGS
TH_3450|M.thermoresistible__bu ADGNARKADLAKLTNGADQLAAGLAQLDTTLRTALAPLSGILSQAQSAGT
Mvan_2900|M.vanbaalenii_PYR-1 AEGRAREHDLTKLTDGADQLAAGLAQLDTTLRRALTPLSGLLSQVQDTGR
MAB_4240c|M.abscessus_ATCC_199 ADLRPQLERMSKLADVMSAMTNELGDGDPARLQQMMPQT--LAMAKELEG
Mb1215|M.bovis_AF2122/97 RMIDERTGDLNRLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQN
Rv1183|M.tuberculosis_H37Rv RMIDERTGDLNRLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQN
MLBr_01231|M.leprae_Br4923 HLIGESTGDLNRLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQK
Mflv_0403|M.gilvum_PYR-GCK AQIGERSGDLTTLADGATTLADSLGDVRSQVNEIAPSLKGIIDTFSSVRT
MAV_1761|M.avium_104 TMINDQTDDLNRLARGAGTLADNLGDVRGQVNQLAASVRELENAFSSTKN
MSMEG_4741|M.smegmatis_MC2_155 TLIDANDANLSTLSGGAHKLADVLGQISTQVTNALVTVRPLAGALADMET
MUL_0757|M.ulcerans_Agy99 --------------TSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHD
:
MMAR_4836|M.marinum_M QVQRFRPLLQQLSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGAL
TH_3450|M.thermoresistible__bu QMQQFRPLLQQLSATAPAVDQAIQAGPGLRPWADQAAHAIAILDPLVGAL
Mvan_2900|M.vanbaalenii_PYR-1 QLQNARPVIEQLNTTAPTVDQALRSGPGLRPLATQASAAIAAVEPLIAGL
MAB_4240c|M.abscessus_ATCC_199 QLDRYQSLISQMGTVAGMVDQLATMGP----SVEATFTALDAGASLAQTL
Mb1215|M.bovis_AF2122/97 QFGGNK-TFNEIDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAAL
Rv1183|M.tuberculosis_H37Rv QFGGNK-TFNEIDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAAL
MLBr_01231|M.leprae_Br4923 MFGDSK-TLGEIDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIAL
Mflv_0403|M.gilvum_PYR-GCK EYGGDK-LVRDVATAAKLVDSVNKLGLSMGINFRAVRDMFAWIGPVLTAL
MAV_1761|M.avium_104 QYSGDA-LVNQVDIAARLVDHVNSLSNAMGWNFTAAKNMFAWIGPVLAAL
MSMEG_4741|M.smegmatis_MC2_155 KYGGEK-TLDQIDQSAELVANMRSLGRAMGVNLARITDVYDWSAPMVRAL
MUL_0757|M.ulcerans_Agy99 LT------QQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYF
* .: :
MMAR_4836|M.marinum_M NTSPWCATTPECTQLRDQVQILVTLRHTGFFNQLANLGDLYQPGS--DTA
TH_3450|M.thermoresistible__bu NTAPWCATTPQCAQIRDQVQVLVTLRNSGFFNQVADLGDRYNPATG-ATV
Mvan_2900|M.vanbaalenii_PYR-1 NASPWCATTPQCAQLRDQTGILVTLRRGGFFDQVADLGDHLGPDT---TL
MAB_4240c|M.abscessus_ATCC_199 AESPFCPVQPDCVTLRDQ---LVELRTTGPLSSVESLRESVRAVTGGKTI
Mb1215|M.bovis_AF2122/97 DTSPVCDSNPMCGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTV
Rv1183|M.tuberculosis_H37Rv DTSPVCDSNPMCGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTV
MLBr_01231|M.leprae_Br4923 DSSVLCDTNPICADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSSQTI
Mflv_0403|M.gilvum_PYR-GCK QGNRVCDANPSCVDTRMQFEKLVSAREDGRVDEINQLAGQLQGVDDRQSL
MAV_1761|M.avium_104 QGNPVCDADSSCSATRATFEQLVGPRGQADLDAIDDLSHQLQAYPDKRAL
MSMEG_4741|M.smegmatis_MC2_155 NVSPECNLDPACAASRSDLQRIVEAKDNGNLDKFAELGRQLESTEGDETL
MUL_0757|M.ulcerans_Agy99 YWEKHCFDIPVCWSLRSVFDTLDGVD----------------------LM
* . * * :
MMAR_4836|M.marinum_M AGTVADVQNTITSLDKTFGALGDPA----DLAGNIRRLQSGISQLASGAQ
TH_3450|M.thermoresistible__bu AETLADIRNAVTAMDKAFGALGDPA----DLAGNIGRLQDGISQLASGAQ
Mvan_2900|M.vanbaalenii_PYR-1 SGTLASLQTAVTTMQQALGVTGDPA----DLAGNMRRLQDGVSQLASGGR
MAB_4240c|M.abscessus_ATCC_199 TQLLGDMNSQFKQIRGLLAKLPEMERKFERIAGYFQQLQGLGVDLNS-VK
Mb1215|M.bovis_AF2122/97 SAVVNDLGRSLNSVVRSLKSLGLDNP--DAARARLISMQNGANDLASAGR
Rv1183|M.tuberculosis_H37Rv SAVVNDLGRSLNSVVRSLKSLGLDNP--DAARARLISMQNGANDLASAGR
MLBr_01231|M.leprae_Br4923 GATVSGLEKTLTAVNTSLRSLGLDNP--NVMRSKMIGLQNGVNDLASAGR
Mflv_0403|M.gilvum_PYR-GCK TATVNQLNGALAQVTKAISAMGLDTP--AGARAGLDDLQDGADRLADGSR
MAV_1761|M.avium_104 KASTDRLRNAFAKLNDVLRAMGMDRP--GGLQSNLTTLQNGADQFAGGSR
MSMEG_4741|M.smegmatis_MC2_155 DEAVSGLQQSIKEATAAARELGLEDA--SSVKRQLDQLEQGVNLLADSSH
MUL_0757|M.ulcerans_Agy99 TEDINNLLPLMERLDTLMPQMTAMMP----------EMIQTMKSMKAQML
: . : :
MMAR_4836|M.marinum_M ALATGVHTLADSNIEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAF
TH_3450|M.thermoresistible__bu ALATGVHTLVDSNLEMLSGMSQIATQLQNSARASADSDSSSGFYLPPNTF
Mvan_2900|M.vanbaalenii_PYR-1 ALASGVHALADSNIQMLGGMSQIAAQLQNSARDTAGSDAAAGFYLPPDSF
MAB_4240c|M.abscessus_ATCC_199 NMGVRIRDLNTQLEDTVRSMGEAAATLQGIGKNSN-SAAASGFSVPGAML
Mb1215|M.bovis_AF2122/97 QVADGVQMLVDQTKNMGIGLNQASAFLMAMGNDAS-QPSMAGFNVPPQVL
Rv1183|M.tuberculosis_H37Rv QVADGVQMLVDQTKNMGIGLNQASAFLMAMGNDAS-QPSMAGFNVPPQVL
MLBr_01231|M.leprae_Br4923 RIADGVAVLVDQTRTMGTSLARASAFLMEMGQDAS-QPSMAGFNVPPQLL
Mflv_0403|M.gilvum_PYR-GCK QVAGGVDQLVEQIKVMAAGLDQAAAFLLTMRNDAS-SSNMAGFSIPAEVL
MAV_1761|M.avium_104 QVADAVAQLVDKVKQLGAGLSESAAFLLSLKHDAA-HPAMAGFNIPAQLL
MSMEG_4741|M.smegmatis_MC2_155 QLAQGVQLLVDQTRNMGQGLDQASQFLLAMKRDAS-DPQMSGFYIPPQIL
MUL_0757|M.ulcerans_Agy99 SMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDS-------FYLPPEVF
: * . . . : . * :* :
MMAR_4836|M.marinum_M ENRQFADVAKHFLSPDGKTARFAIESSYDPYSSDAMNLAHKITEVADAAR
TH_3450|M.thermoresistible__bu ENRQFADVAKQFLSPDGKTARFAIESSHDPYSVDAMNLAHTITDVADAAR
Mvan_2900|M.vanbaalenii_PYR-1 ENRQFSDVARQFVSADGRTARFAITSSHDPFSAEAMELNGRIIDTANAAT
MAB_4240c|M.abscessus_ATCC_199 QNPGFKELSAAFLQDDGRTAMYMIQSPLNPYGPEAMQLSRDMERVGNEAT
Mb1215|M.bovis_AF2122/97 KSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQ
Rv1183|M.tuberculosis_H37Rv KSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQ
MLBr_01231|M.leprae_Br4923 NTEDFKKLVQAFISPDGHSVRYFIQTDLNPFSSAAMDQVNTILNVATGAQ
Mflv_0403|M.gilvum_PYR-GCK GAVEFQKASEAFVSPDGHSVRYLVQTKLNPFSSEAMDQVNTISDIARGAQ
MAV_1761|M.avium_104 RLPQFQEAAKVFISPDGHSVRYLVQSKLSPFSTQAMDQVDAITATARGAQ
MSMEG_4741|M.smegmatis_MC2_155 TQEEFNKAAALFVSPDGRSVRYLVQTALDPFGTAAMDQVKDIVKTAESAR
MUL_0757|M.ulcerans_Agy99 NNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAI
* *:. **::. : : .* . .:: : . *
MMAR_4836|M.marinum_M PNTSLANATVSMAGFPAVNSDIQRLLSADFHQLAFATLVIVGLILVVLLR
TH_3450|M.thermoresistible__bu PNTSLAHATVSVAGFPAVNSDIARLLWADFAQLAIATIVIVGLILVLLLR
Mvan_2900|M.vanbaalenii_PYR-1 PNTSLAGTSISIVGFPALNSDLQQLLSTDFARLGAATLLVVGIVLVLLLR
MAB_4240c|M.abscessus_ATCC_199 PNTALAGAKVSVGGFPAINADLKKAYDSDLREIIVVTLLIIFLVMCLLLR
Mb1215|M.bovis_AF2122/97 PNTSLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLR
Rv1183|M.tuberculosis_H37Rv PNTSLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLR
MLBr_01231|M.leprae_Br4923 PNTTLSDASIYLSGYTVTLRDTRDYYDRDLQLIVIVTMIVVLLILMALLR
Mflv_0403|M.gilvum_PYR-GCK PNTMLSDASISMGGFPAALRDTRDYYERDIRFIIVVTLVIVMLVLMLLLR
MAV_1761|M.avium_104 PNTALADAEVSMAGYTVGLKDTRDYYQHDIKFIIAVTLLVVLLTLMALLR
MSMEG_4741|M.smegmatis_MC2_155 PNTSLTDAKISLVGFSSIQNEMRNYYDGDLRFIITVTLIVVFLILAALLR
MUL_0757|M.ulcerans_Agy99 KGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITR
.* * : : : * : *: :: :: : : : *
MMAR_4836|M.marinum_M ALVAPLYLLGTVVLNYGAALGLGTLVFQYGLGKEIAWPVPLLAFIILVAV
TH_3450|M.thermoresistible__bu ALLAPIYLLGTVVLNYLASLGIGVLVFQYLLGHEIAWPVPLLAFIILVAV
Mvan_2900|M.vanbaalenii_PYR-1 AIVAPLYLLGTVVLNYAAALGIGVLVFQYGFGQAIAWPVPLLAFILLVAV
MAB_4240c|M.abscessus_ATCC_199 AVVAPLYLLGTVLLTYIASLGIGVLVFQVLLGQQLDWAVPAMTFVLIVAV
Mb1215|M.bovis_AF2122/97 AIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAV
Rv1183|M.tuberculosis_H37Rv AIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAV
MLBr_01231|M.leprae_Br4923 SIVAPIYLVGSVIVSYLSALGLCVLVFQVLLRQQLHWSVPGLAFVVLVAV
Mflv_0403|M.gilvum_PYR-GCK SLIAPLYLVGSVVVSYFAAIGIGVLVFQLLLGQQLHWSVPPLAFVVLVAV
MAV_1761|M.avium_104 AIVAPLYLVATVVISYLSAVGVGVLVFQFLLGQQLHWSVPPLAFVVLVAV
MSMEG_4741|M.smegmatis_MC2_155 SIIAPIYLVLSVVLSYMSALGIGVVFFQFILGKEIVWTVPGMAFLVLVAV
MUL_0757|M.ulcerans_Agy99 SVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAV
:::*. :: :*::. ::.*: .:.:* : : * * ::.::::**
MMAR_4836|M.marinum_M GADYNMLLISRLREESAHNIRVGVLRTVANTGSVITSAGLIFAASMFGLI
TH_3450|M.thermoresistible__bu GADYNMLLVSRLREESGTNIRVGVLRTVANTGSVITSAGVIFAASMFGLM
Mvan_2900|M.vanbaalenii_PYR-1 GADYNMLLISRLREESGRSVRVGVLRTVASTGSVITSAGIIFAVSMFGLM
MAB_4240c|M.abscessus_ATCC_199 GADYNMLFISRLREESARNMRVGIIRTVRQTGSVITSAGLVFAASLLGMM
Mb1215|M.bovis_AF2122/97 GADYNMLLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLL
Rv1183|M.tuberculosis_H37Rv GADYNMLLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLL
MLBr_01231|M.leprae_Br4923 GADYNMLLASRLRDESSHGLRASVIRTVRSTGGVITAAGLIFAASMFGLL
Mflv_0403|M.gilvum_PYR-GCK GADYNMLFVSRMRDESPHSVRFGIIRTLGSTGGVITAAGLIFAASMAGLL
MAV_1761|M.avium_104 GADYNMLLVSRMRDESPHSMRYGIIRTLSSTGGVITAAGLIFAASMSGLL
MSMEG_4741|M.smegmatis_MC2_155 GADYNLLLISRIRDEAAHGMRTAVIRTIGATGGVITSAGLIFAASMFGLT
MUL_0757|M.ulcerans_Agy99 GADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFA
*****:*: :*:::* .:. .::*:: :*.*:*:**::** :: .:
MMAR_4836|M.marinum_M AGSIAIMIQAGFIIGCGLLLDTFVVRTLTVPAIATLLREASWWPQRKPLT
TH_3450|M.thermoresistible__bu FGSIAIMIQAGFIVGCGLLLDTFLVRTLTVPAIATLLREASWWPQPNRAR
Mvan_2900|M.vanbaalenii_PYR-1 TGSVHIMVQAGFIIGCGLLLDTFVVRTLTVPAIATLLREKSWWPQR----
MAB_4240c|M.abscessus_ATCC_199 VGSVNQMVQMGFIIGVGILLDTFVVRTLMVPTLAQAFGKLSWWPSKA---
Mb1215|M.bovis_AF2122/97 FSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWWPGHPWQR
Rv1183|M.tuberculosis_H37Rv FSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWWPGHPWQR
MLBr_01231|M.leprae_Br4923 LSSIATVVQAGFVLGSGILLDTFIVRTITVPAVAALLRRASWWPARPWGN
Mflv_0403|M.gilvum_PYR-GCK FSSIGIVVQGGFVIGVGILLDTFVVRTITVPAIATLLGRANWWPSRVAAP
MAV_1761|M.avium_104 FSSIGTVVQGGVVIGVGILLDTFLVRTVTVPAIAALAGRANWWPSRIAVR
MSMEG_4741|M.smegmatis_MC2_155 FSSLLAAVQIGFIIGVGLLLDTFLVRTITVPAAAVLIGKLSWWPTKPPAP
MUL_0757|M.ulcerans_Agy99 VSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQR
..: * * :* *:*:**::**:. .*: * . ***
MMAR_4836|M.marinum_M HNG--------------------------
TH_3450|M.thermoresistible__bu -----------------------------
Mvan_2900|M.vanbaalenii_PYR-1 -----------------------------
MAB_4240c|M.abscessus_ATCC_199 -----------------------------
Mb1215|M.bovis_AF2122/97 CAPEEGQMSARMSARTKTVFQAVADGSKR
Rv1183|M.tuberculosis_H37Rv CAPEEGQMSARMSARTKTVFQAVADGSKR
MLBr_01231|M.leprae_Br4923 NA---------------------------
Mflv_0403|M.gilvum_PYR-GCK ARERVSADT--------------------
MAV_1761|M.avium_104 -RNPVSGQP--------------------
MSMEG_4741|M.smegmatis_MC2_155 EPAPTEPTVAPAAQA--------------
MUL_0757|M.ulcerans_Agy99 PAPQPWPTPAPTPPPATTSV---------