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MRLKVLLTLAVLSIISLVGAVYMAFGVLDIASTSKTNHMTLMLNSSGGLMSTSQVTLRGIKVGRVTDIQA TATGLAVSMALDSGYPIPVDSQVSVQNLSAAGEQYVEFKPVRIEPPYYSDGAVIPASKAAPVYTVSDLLQ KGNALMQAMDADALETTLNNVAAGFVDNTKTIDELATTARLFAQMVNDDKHYLAELIGNTSTITNGLGEI RAGDILKQSAKTVPRSLAGLGDLVKVIEKLEPIVEAGMGDGKPLTDLVDKLFDYINALSEPLSEFTTVLE PIVAPLRDVKLDAGHWLDFWDSTFNNQGGLRIHLGVPEWPQPDPHQTAPGTQPAQPTAKPSAPQPTPAPQ TATAGRSGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4035 | - | - | 100% (359) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1005c | - | 8e-22 | 36.36% (154) | putative MCE family protein |
| M. abscessus ATCC 19977 | MAB_4594c | - | 1e-20 | 32.00% (150) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0610 | mce2F | 2e-21 | 24.22% (351) | MCE-family protein MCE2F |
| M. gilvum PYR-GCK | Mflv_2513 | - | 1e-22 | 26.95% (256) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0594 | mce2F | 2e-21 | 24.22% (351) | MCE-family protein MCE2F |
| M. leprae Br4923 | MLBr_02594 | mce1F | 2e-19 | 25.63% (355) | putative secreted protein |
| M. marinum M | MMAR_4705 | - | 3e-23 | 29.14% (278) | MCE-family protein |
| M. avium 104 | MAV_0953 | - | 3e-21 | 26.26% (278) | mce-family protein mce1f |
| M. smegmatis MC2 155 | MSMEG_4785 | - | 6e-23 | 29.24% (277) | mce-family protein mce1f |
| M. thermoresistible (build 8) | TH_4161 | - | 2e-23 | 29.30% (273) | PUTATIVE virulence factor mce family protein |
| M. ulcerans Agy99 | MUL_3801 | mce5F | 3e-21 | 27.95% (229) | Mce family protein Mce5F |
| M. vanbaalenii PYR-1 | Mvan_4145 | - | 2e-22 | 27.41% (259) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4705|M.marinum_M ----------MLTRFVRIQLAIFAIVGMVGVAVMAVWYIQAPTL---LGI
MAV_0953|M.avium_104 ----------MLTRFVRIQLAIFLIAGTIGVISMVLFYIQAPTL---LGI
TH_4161|M.thermoresistible__bu ----------MLTRFVRTQLVIFTIAAVVGMGAMVFGYLQVPML---LGI
MSMEG_4785|M.smegmatis_MC2_155 ----------MLTRFIRTQLIIFTIASIVGVAVMLFAYMQVPTL---LGL
Mflv_2513|M.gilvum_PYR-GCK ----------MLTRFVRNQLIIFTIASIVGVAVMIFSYMQVPTL---LGI
Mvan_4145|M.vanbaalenii_PYR-1 ----------MLTRFVRNQLIIFTIASIVGVAVMLFAYMQVPTL---LGV
Mb0610|M.bovis_AF2122/97 ----------MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSL---VGI
Rv0594|M.tuberculosis_H37Rv ----------MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSL---VGI
MLBr_02594|M.leprae_Br4923 ----------MLTPLIRRQLVLFAILTVISLTVLGVYYLQIPSL---VGI
MAB_4035|M.abscessus_ATCC_1997 -----------MRLKVLLTLAVLSIISLVGAVYMAFGVLDIAST---SKT
MUL_3801|M.ulcerans_Agy99 MITPIANAVVRVVRAGHRQQTWLSVAGLVLTLVVAAAYLLVGALRLTPFA
: : : : : :
MMAR_4705|M.marinum_M GKMTVTLELPATGGLYRFSNVTYRGVQIGKVTALGLTSSGAKATLALDAS
MAV_0953|M.avium_104 GRMTVTLELPATGGLYRFSNVTYRGVQLGKVTAVGLTPSGVKATLSLSTS
TH_4161|M.thermoresistible__bu GRISVTMELPSTGGLYRFSNVTYRGVKVGKVLDVRPTRTGAVVTMSLQSR
MSMEG_4785|M.smegmatis_MC2_155 GRITVTLQLPATGGLYQFSNVTYRGSQIGKVTAVELTETGAEATLSLDRS
Mflv_2513|M.gilvum_PYR-GCK GRLAVTLELPASGGLYRFSNVTYRGVQVGKVTEVNLTENGAEAILSLDTS
Mvan_4145|M.vanbaalenii_PYR-1 GRLVVTLELPESGGLYRFSNVTYRGVQVGKVTGVSLTENGAEATLSLETS
Mb0610|M.bovis_AF2122/97 GRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNG
Rv0594|M.tuberculosis_H37Rv GRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNG
MLBr_02594|M.leprae_Br4923 GRYSLKAELSATGGLYPTANVTYRGIAIGKVTDVEPTATGAEATMSIDSR
MAB_4035|M.abscessus_ATCC_1997 N--HMTLMLNSSGGLMSTSQVTLRGIKVGRVTDIQATATGLAVSMALDSG
MUL_3801|M.ulcerans_Agy99 SSYRVTVSLPESGGLLPNQDVALRGVRIGRIESLHLTESGVDAIASITSQ
. : * :*** :*: ** :*:: : * * . ::
MMAR_4705|M.marinum_M PKIPADLKAEVRSISAVGEYYVDLRPRTDSPPYLHDGSVIARDRAVIGQP
MAV_0953|M.avium_104 PKVPADLTAEVLSVSAVGEQYVDLRPRTNSPPYLHDGSVIAMRDTKIPQP
TH_4161|M.thermoresistible__bu PRIPADLQADVRSVSAVGEQYVELLPRHDGAPYLEDGSVIGIENTSVPQR
MSMEG_4785|M.smegmatis_MC2_155 PKVPADLQAQVRSMSAVGEQYVELLPRKDSGPYLENGSVIPASETTIPQA
Mflv_2513|M.gilvum_PYR-GCK PEIPADLRAEVRSVSAVGEQYVELLPQTDDGPFLEDGSRIPVSNTTIPQQ
Mvan_4145|M.vanbaalenii_PYR-1 PKIPADLQAEVLSVSAVGEQYVDLRPNTDEGPYLEDGARIPVANTTVPQQ
Mb0610|M.bovis_AF2122/97 YQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITT--TTVPSQ
Rv0594|M.tuberculosis_H37Rv YQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITT--TTVPSQ
MLBr_02594|M.leprae_Br4923 YKIPIDSAANVHSVSAVGEQYLDLVSSGNPGKYLAPGQTITK--SKIPIE
MAB_4035|M.abscessus_ATCC_1997 YPIPVDSQVSVQNLSAAGEQYVEFKPVRIEPPYYSDGAVIPASKAAPVYT
MUL_3801|M.ulcerans_Agy99 VKIPASSTVHVSALSPAGEQFLDFEPESDTGPYLSEGAVIGVDQARVPVS
:* . . * :*..** :::: . : * * :
MMAR_4705|M.marinum_M IGPVLDQTSALINSIPKGKLSTLLDESFNAFNGAGYDFGSLFDSSAQLSG
MAV_0953|M.avium_104 VGPMLDQVNALVQSIPKTKLGQLLDESFQGFNGSGYDLGSLIDSSQTLSR
TH_4161|M.thermoresistible__bu VGPMLDQMSALIDSIPSGQLGALLDESATALGGSGYELGSAFDSAAQLAE
MSMEG_4785|M.smegmatis_MC2_155 VGPMLDQLSALVDTIPKDKLSQLLDESYDAFNGTGFDFGSLLDSASTITT
Mflv_2513|M.gilvum_PYR-GCK VGPMLDQMSALVGSLPKDRIPDLLDETFKAFNGAGPEFGSLLDSATTLAA
Mvan_4145|M.vanbaalenii_PYR-1 VGPMLDQLSALVGSLPKDRIPDLLDETFKAFNGAGPDFGSMLDSAATLTN
Mb0610|M.bovis_AF2122/97 IGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAH
Rv0594|M.tuberculosis_H37Rv IGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAH
MLBr_02594|M.leprae_Br4923 IGPALDSVNRGLAALPKEKIGSLLDETAQAVGGLGPALQRLVSSTQAIVD
MAB_4035|M.abscessus_ATCC_1997 VSDLLQKGNALMQAMDADALETTLNNVAAGFVDNTKTIDELATTARLFAQ
MUL_3801|M.ulcerans_Agy99 LAQLLGDANGLRAQIDPHQVELIKKVLSLSQAGP-KKLAAIVDGGTFLLS
:. * . : : . . . : :
MMAR_4705|M.marinum_M DLNGIADRTRTLTEDSGPFLDAQAQTTDSIRLWARSLAGVSGQLATNDPQ
MAV_0953|M.avium_104 DANGVVDRTRALTEDTGPLLDTQAQTTDSIRTWARSFAGISDVMVNNDSH
TH_4161|M.thermoresistible__bu RLNGSGERARVLIEDGRPLLDGQAVGAEAIRTWARSLSGITGQLAADDAQ
MSMEG_4785|M.smegmatis_MC2_155 DASAVSDQTRALIDDSGPFLDAQAQTADSIRTWARSLAGITGTVSDDDAQ
Mflv_2513|M.gilvum_PYR-GCK DMNGISEQTRALIDDSGPLLESQAETTDAIRTWARSLNGISAQVVQNDPQ
Mvan_4145|M.vanbaalenii_PYR-1 DVNGVSDQMRSLIDDSGPLIDSQAETADAIRTWAQSLNGISAQVVQNDPQ
Mb0610|M.bovis_AF2122/97 DVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPA
Rv0594|M.tuberculosis_H37Rv DVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPA
MLBr_02594|M.leprae_Br4923 AFKTNITDVNDIIQNSGPILDSQVKSDNAIERWVHNLNVLAAQSARQDQH
MAB_4035|M.abscessus_ATCC_1997 MVNDDKHYLAELIGNTSTITNGLG------EIRAGDILKQSAKTVP----
MUL_3801|M.ulcerans_Agy99 TLDSVLPETTSIIRTSRVVLNLIADKNAGLAATAVTLDRTLAGVARMQGG
: . : . :
MMAR_4705|M.marinum_M IRTLLERGPGAFNEASRLLDQIKPTLPVLLANLTTVGQIAVTYHASVEQI
MAV_0953|M.avium_104 FRTILEKGPETANEASRLLDQIKPTLPVLLANLTTIGQIGITYHPSLEQL
TH_4161|M.thermoresistible__bu IRTILTDGPGAADQAARLLAQVKPTVPVLLANLTTVGQIGVTYNPSLEQL
MSMEG_4785|M.smegmatis_MC2_155 IRTVLREGPGFAQETSRLLDGIKPTLPVLLANLTTIGQIAVTYNPSIEQL
Mflv_2513|M.gilvum_PYR-GCK VRALLQQGPGFAQEVSSLLNQVKPTLPILLANMSTVGQTLLTYNPALEQL
Mvan_4145|M.vanbaalenii_PYR-1 VRALLQQGPAFAQEVSALLNQVKPTLPILLANLSTVGQTLLTYNPAIEQL
Mb0610|M.bovis_AF2122/97 VRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQA
Rv0594|M.tuberculosis_H37Rv VRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQA
MLBr_02594|M.leprae_Br4923 LKSILSQAAPTADEVNTVFSDVRDSLPQTLANFEILIDMLKRYHHGVEQM
MAB_4035|M.abscessus_ATCC_1997 -RSLAGLG-----DLVKVIEKLEPIVEAGMGDGKPLTDLVDKLFDYINAL
MUL_3801|M.ulcerans_Agy99 YRSLTERTPHTLAAIDHLFADNSDTMVQLLGSMATAAQLLYLRVPALNAL
::: : : :.. : ::
MMAR_4705|M.marinum_M LVLLPPFTAAIQSF-LGTKSPVGLATGAFNLIISDPPACTVGFLPPSQWR
MAV_0953|M.avium_104 LVLLPSAVAIEQAA-AAPNHPEGTAQGDFALTIDDPPICTVGFMPPNTWR
TH_4161|M.thermoresistible__bu LVLLPPYLAATQSYGSSLNNPTGMALSEFSLTLGDPPACTVGFLPPSEWR
MSMEG_4785|M.smegmatis_MC2_155 LVLLPPYVAQIQTY-TPTNSPAGLPNGEFSLGLGDPSSCTVGFLPPSAWR
Mflv_2513|M.gilvum_PYR-GCK LVLFPGIIAAQQSFGLPQNSPTGLPTGDFALTISDPNPCTVGFLPSSQWR
Mvan_4145|M.vanbaalenii_PYR-1 LVLFPGIIAAQQSFGLPQNSPTGLPMGDFALTISDPNPCTVGFLPSTQWR
Mb0610|M.bovis_AF2122/97 LVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQ--PPPCLTGFLPASEWR
Rv0594|M.tuberculosis_H37Rv LVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQ--PPPCLTGFLPASEWR
MLBr_02594|M.leprae_Br4923 LVFLPQGASIAQTASATFPNMAALDLA-LSINQ--PPPCLTGFIPAAEWR
MAB_4035|M.abscessus_ATCC_1997 SEPLSEFTTVLEPIVAPLRDVK---------------------LDAGHWL
MUL_3801|M.ulcerans_Agy99 FPDYRG--SVLDALASAFHDHGVWATAELYPRYTCDYGTPSYLPSAADYP
: :. . :
MMAR_4705|M.marinum_M NPADTTIVDTPDGLYCKLPQDS-PIGVRGARNYPCMGQPGKRAPTVEICE
MAV_0953|M.avium_104 SPDDLSDIDTPDGLYCKLPQDS-PLSVRGARNYPCMGHPGKRAPTVEICN
TH_4161|M.thermoresistible__bu SPADLSDIDTPDGLYCKLPQDS-PIGVRGARNFPCMGQPGKRAPTVEICE
MSMEG_4785|M.smegmatis_MC2_155 SPADESDMDTPDNLYCKLPQDS-PVAVRGARNYPCMAHPGKRAPTVELCN
Mflv_2513|M.gilvum_PYR-GCK APEDETTIDTPDGLYCKLPQDS-PMNVRGARNYPCLEHPGKRAPTVELCN
Mvan_4145|M.vanbaalenii_PYR-1 SPEDETTIDTPDGLYCKLPQDS-PMNVRGARNYPCIEHPGKRAPTVELCN
Mb0610|M.bovis_AF2122/97 SPADTSTAPLPKGTYCRIPMDA-SNVVRGARNNPCVDVPGKRAATPRECR
Rv0594|M.tuberculosis_H37Rv SPADTSTAPLPKGTYCRIPMDA-SNVVRGARNNPCVDVPGKRAATPRECR
MLBr_02594|M.leprae_Br4923 SPADTSLQPLPVGTYCKIPMDTPANSVRGSRNIPCVDVPGKRAASPRECR
MAB_4035|M.abscessus_ATCC_1997 DFWDSTFNNQGG--------------LRIHLGVPEWPQPDPHQTAPG---
MUL_3801|M.ulcerans_Agy99 EPFMYTYCRDDDP----------AVSIRGAKNAPRPGGDDTAGPPPGADL
: :* . * . ..
MMAR_4705|M.marinum_M SDQPFEPLAMRQHIFGTYPLDPNLIAQGIPPDDRANWNRERIFGPVEGTP
MAV_0953|M.avium_104 SDQPFMPLAMKQHVLGPYPLDPNLLAQGVPPDDRVTVN-DRIFGPVEGTP
TH_4161|M.thermoresistible__bu SDRPFEPLAMRQHVTGPYPIDPNLIAQGVAPDSRVTSD-DQIFGPPAGTP
MSMEG_4785|M.smegmatis_MC2_155 DPNGYQPLAQRQHTLGPYPFDPNLIAQGVAPDSRVRPD-DKIFGPLQGSP
Mflv_2513|M.gilvum_PYR-GCK DPRGFVPMAIRQHITGPYPFDPNLVAQGIPIDDRVSGD-ERIHAPVQGTP
Mvan_4145|M.vanbaalenii_PYR-1 DPRGFVPTAIRNHITGPYPFDPNLVSQGVPIDSTVEGP-DRIYLPPEGTP
Mb0610|M.bovis_AF2122/97 SNEAYVPGGTN-----PWYGDPNQMLSCPAPAARCDQP----VKPGQVIP
Rv0594|M.tuberculosis_H37Rv SNEAYVPGGTN-----PWYGDPNQMLSCPAPAARCDQP----VKPGQVIP
MLBr_02594|M.leprae_Br4923 DSKPYVPLGTN-----PWFGDPNQLLTCPAPGARCDQP----VKPGLVIP
MAB_4035|M.abscessus_ATCC_1997 -TQPAQPTAKP---------------------------------------
MUL_3801|M.ulcerans_Agy99 GRRTDP--------------------------------------------
.
MMAR_4705|M.marinum_M LPPGVGP------PEETVMPPGPLG---PPSPMG----------------
MAV_0953|M.avium_104 LPPGAVPRGAPAGPRGENPPPGSVGAAVPPVPSSG-------PPALAPMS
TH_4161|M.thermoresistible__bu PP-------------ADDTPP-----------------------------
MSMEG_4785|M.smegmatis_MC2_155 LPPGVTAP-PQGPPPAPQPPPNFAGTNPGPMLPGQPIYVDPPVPGQPPAP
Mflv_2513|M.gilvum_PYR-GCK LPPGAQRAG-TPPVSEPGTPPFPVGPPGPPAPGV----------------
Mvan_4145|M.vanbaalenii_PYR-1 LPPGAVRAG-TPPVSEPGTPPFPVGAPAPMVPG-----------------
Mb0610|M.bovis_AF2122/97 APSVNNGINPLPADQLPGTPPPVNDPLQRPGSGT----------------
Rv0594|M.tuberculosis_H37Rv APSVNNGINPLPADQLPGTPPPVNDPLQRPGSGT----------------
MLBr_02594|M.leprae_Br4923 APTVDNGLNPAPADRLPGTPPPVSDPLSQPRSGS----------------
MAB_4035|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3801|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4705|M.marinum_M ----EVSPIAPIDVPS-------TPPPAPSG-------APSAAPSGLGRA
MAV_0953|M.avium_104 RMSADLPPIAPLDVPTPTELPPPPPPPAPAAPDQVDGAAPQAAPSAFAGK
TH_4161|M.thermoresistible__bu ---------------------------------------PGAAPASASAE
MSMEG_4785|M.smegmatis_MC2_155 IRNPEIVPLPPAQLPQATEVPVPHGLTAPPPATDPG--APVAAPSAFDGG
Mflv_2513|M.gilvum_PYR-GCK APAPSQPLFVPPAPPAVLPPGQGPLLPNQAVPAPPG-GAVPAAPSAFGGN
Mvan_4145|M.vanbaalenii_PYR-1 APPPAQPPILPPAP---LLPGQGPLLPGQAVPVAPASGAVPVAPSAFGSN
Mb0610|M.bovis_AF2122/97 ----------------------------------------VQCNGQQPNP
Rv0594|M.tuberculosis_H37Rv ----------------------------------------VQCNGQQPNP
MLBr_02594|M.leprae_Br4923 ----------------------------------------VQCNGQQPNT
MAB_4035|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_3801|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4705|M.marinum_M AARPGPSVAFAQYDPHTGSYVAPDGQVYRQTDLIIPDTPKAPRTWKDMLP
MAV_0953|M.avium_104 ASKPAPSVVVAKYDPRTGRYVGPDGKLYQQSDLVT---PKAPKTWKDMLP
TH_4161|M.thermoresistible__bu ATDGGPSVAFATYNPRTGQYATPDGLVHTRTDLVAP----PAQNWTDLLP
MSMEG_4785|M.smegmatis_MC2_155 KS-SGPAVTVAKYNPRNGEYMGADGKLYRQANLVGN-----AKSWQDLMP
Mflv_2513|M.gilvum_PYR-GCK AS-GGPSVATAAYDPNTGQYLSPDGAMHQISNVTPG---GTPKSWKDLLP
Mvan_4145|M.vanbaalenii_PYR-1 DS-GVPTVGTAQYNPQTGEYIAPDGSMNRVTNVASG---ANPKSWKDLLP
Mb0610|M.bovis_AF2122/97 CVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAG----ADGWKVMLA
Rv0594|M.tuberculosis_H37Rv CVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAG----ADGWKVMLA
MLBr_02594|M.leprae_Br4923 CVYTPSGPPSAVYSPQSGELVGPDGVAYAVENSTKTG----DDGWKEMLA
MAB_4035|M.abscessus_ATCC_1997 ---SAPQPTPAPQTATAGRSGS----------------------------
MUL_3801|M.ulcerans_Agy99 ----TPRGRFTIPTPYGGPVLPIEPPH-----------------------
. : *
MMAR_4705|M.marinum_M T--
MAV_0953|M.avium_104 T--
TH_4161|M.thermoresistible__bu R--
MSMEG_4785|M.smegmatis_MC2_155 S--
Mflv_2513|M.gilvum_PYR-GCK M--
Mvan_4145|M.vanbaalenii_PYR-1 M--
Mb0610|M.bovis_AF2122/97 PTG
Rv0594|M.tuberculosis_H37Rv PTG
MLBr_02594|M.leprae_Br4923 PAG
MAB_4035|M.abscessus_ATCC_1997 ---
MUL_3801|M.ulcerans_Agy99 ---