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RKFSDQITDPVLKKRVAGFIGQESVHGQEHRRVNEKLIEMGYPIAWLDSKKQVDRLIRFENMLPPRAHLA FTAMAEHMTAILAERTLGSDEVQAIPGDPEVWHLLNWHALEELEHKSVAFDVYRAVGGTETMRIGLMLAA MTIVPPLTLGILAGSLLADPVARRQPLRLLREARGLFGGPLFKGIVGDVRKYLRPGFHPDDINTDELLER WQQELFGSKGILVDHLK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4025c | - | - | 100% (228) | hypothetical protein MAB_4025c |
| M. abscessus ATCC 19977 | MAB_2967c | - | 2e-69 | 56.03% (232) | hypothetical protein MAB_2967c |
| M. abscessus ATCC 19977 | MAB_4451c | - | 4e-64 | 51.46% (239) | hypothetical protein MAB_4451c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 2e-16 | 29.44% (214) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_4629 | - | 1e-43 | 44.20% (224) | metal-dependent hydrolase |
| M. tuberculosis H37Rv | Rv2777c | - | 2e-16 | 29.44% (214) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3143 | - | 7e-42 | 43.75% (224) | hypothetical protein MMAR_3143 |
| M. avium 104 | MAV_3671 | - | 4e-15 | 30.37% (214) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3675 | - | 9e-13 | 28.77% (219) | metal-dependent hydrolase |
| M. thermoresistible (build 8) | TH_1630 | - | 1e-08 | 29.63% (135) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2157 | - | 2e-17 | 30.88% (217) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_0314 | - | 3e-44 | 45.09% (224) | metal-dependent hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4629|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0314|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3143|M.marinum_M --------------------------------------------------
MAB_4025c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_3671|M.avium_104 --------------------------------------------------
MSMEG_3675|M.smegmatis_MC2_155 --------------------------------------------------
TH_1630|M.thermoresistible__bu --------------------------------------------------
Mflv_4629|M.gilvum_PYR-GCK ------------MSDDSSTRPTTRVVPKPRRVRFDMPAETSRQHFVDGDL
Mvan_0314|M.vanbaalenii_PYR-1 ------------MSDDSSTRPTTRVVPKPRRVRFDMPAGTSRQHFVDGDL
MMAR_3143|M.marinum_M ------------MPEDRAS-TKSRVLPKPRRVRFPMPTSTKRRHFVDGDL
MAB_4025c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLP--FHYVPNEP
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLP--FHYVPNEP
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLP--FHYVPNEP
MAV_3671|M.avium_104 -MVIIDNQAAGPHDAS---VDHERLVLEARDVDFDWAQLP--FHYAPGEP
MSMEG_3675|M.smegmatis_MC2_155 --------MLRPLRFD-HEIDPGPVQIQARKVHFDLSDIP--LHWIPGHP
TH_1630|M.thermoresistible__bu -----------------------MTELRIRRIRFDFDETVP-FNWNTANP
Mflv_4629|M.gilvum_PYR-GCK VMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEATH
Mvan_0314|M.vanbaalenii_PYR-1 VMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEATH
MMAR_3143|M.marinum_M VMSHFISVLSATFPEGEDFFIRSVKYFQSSIDDPQLLTAVKGFIGQEATH
MAB_4025c|M.abscessus_ATCC_199 -----------------------MRKFSDQITDPVLKKRVAGFIGQESVH
Mb2799c|M.bovis_AF2122/97 MATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMH
Rv2777c|M.tuberculosis_H37Rv MATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMH
MUL_2157|M.ulcerans_Agy99 LPTHVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAMH
MAV_3671|M.avium_104 FATHVLNVLHLLLPAGEQFFVEVFKQALPLIRDDQLRLDVQGFIGQEGVH
MSMEG_3675|M.smegmatis_MC2_155 VASTMVNLFNVVLPVAEHWFVDTFNEALPYVRDPKLADDMRGFIGQEATH
TH_1630|M.thermoresistible__bu AFSTYMNMVSIMAICFEKMLVAAVREAMPLITDPAVAEEADAFLRQEAQH
.. : * : .*: **. *
Mflv_4629|M.gilvum_PYR-GCK RHQHRLLNDRLQ--AMGYPTEGID--RHIKKLVGRLEKRFSPKMR-----
Mvan_0314|M.vanbaalenii_PYR-1 RHQHRLLNDRLQ--AMGYPTEGID--RHIKKLVGRLEKRFSPRMR-----
MMAR_3143|M.marinum_M RHQHRLLNERLQ--AMGYPTARID--RHVARLIKRLERRFSPEMR-----
MAB_4025c|M.abscessus_ATCC_199 GQEHRRVNEKLI--EMGYPIAWLDSKKQVDRLI-RFENMLPPRAH-----
Mb2799c|M.bovis_AF2122/97 SQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLL
Rv2777c|M.tuberculosis_H37Rv SQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLL
MUL_2157|M.ulcerans_Agy99 SQAHSGVLAHFE-AQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWLL
MAV_3671|M.avium_104 SRAHANVLAHFA-ARGIDLRPYTGQIEWLFGTLLGPRPNWSPRRRQSWLL
MSMEG_3675|M.smegmatis_MC2_155 AETHDKVLEEFLTAHDVHYQPILELVDHVFNTMLAPKPATDPRRRLNDLC
TH_1630|M.thermoresistible__bu AGAHRRHVRALI----RSHPGLQQTLDAAIGAYDQLTETTSLRHR-----
* : . :
Mflv_4629|M.gilvum_PYR-GCK --LAVTAALEHYTATFAEIILTSDEAQELIGYTEVRPILLWHALEECEHK
Mvan_0314|M.vanbaalenii_PYR-1 --LAVTAALEHYTATFAEIILTSDEAQELIGDTEVRPILLWHALEECEHK
MMAR_3143|M.marinum_M --LSMTSALEHYTATLAEIILTSDDAQKLIGQTEVRPILLWHAFEESEHK
MAB_4025c|M.abscessus_ATCC_199 --LAFTAMAEHMTAILAERTLGSDEVQAIPGDPEVWHLLNWHALEELEHK
Mb2799c|M.bovis_AF2122/97 EQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHK
Rv2777c|M.tuberculosis_H37Rv EQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHK
MUL_2157|M.ulcerans_Agy99 EQVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEHK
MAV_3671|M.avium_104 EQISLVSAIEHYTAILGEWILDSPAHDRIGTDPVMLDMLRWHGAEEVEHK
MSMEG_3675|M.smegmatis_MC2_155 DRLWLIAAIEHYTAVLGDFVLN-CAWDDHHADPTLTDLFRWHGAEEVEHR
TH_1630|M.thermoresistible__bu --LAYVADLEAAFTPFFTMLLDHEAALFRPGDDRVASLFVWHFVEEIEHR
: : * : : * : :: ** ** **:
Mflv_4629|M.gilvum_PYR-GCK AVAFDVYETVGGSERTRVWGMRIASLLLFTELVIQTTRS--LAGDRAAYN
Mvan_0314|M.vanbaalenii_PYR-1 AVAFDVYETVGGSERTRVWGMRIASLLLFSELVIQTTRS--LAGDRAAYN
MMAR_3143|M.marinum_M AVAFDAYRLIGGTERTRVRGMRIASAILFGELILQTALS--MASDKASYN
MAB_4025c|M.abscessus_ATCC_199 SVAFDVYRAVGGTETMRIG-LMLAAMTIVPPLTLGILAGSLLADPVARRQ
Mb2799c|M.bovis_AF2122/97 AVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGT
Rv2777c|M.tuberculosis_H37Rv AVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGT
MUL_2157|M.ulcerans_Agy99 AVAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPGT
MAV_3671|M.avium_104 AVAFDTMKHLRAGYWRQVRTQLVVTPAMLLLWIRGVRFMYSRDPYLPPHT
MSMEG_3675|M.smegmatis_MC2_155 SVAHDVAVYFQDSYLARVRAMTIAATAVYMFFQRGTWAMIRKDPTVDIGW
TH_1630|M.thermoresistible__bu SSALLIYDAVVGDKWYRMRALPRIVRHLMHVVLLITNGINEHVPPADRAI
: * . :: :
Mflv_4629|M.gilvum_PYR-GCK P-----VRLLRSLRAFRH--NPLFSRAAIER-----------FRSYTHAG
Mvan_0314|M.vanbaalenii_PYR-1 P-----VRLLRSLRAFRH--NPLFSSAAIER-----------FRSYSRGG
MMAR_3143|M.marinum_M P-----VTLVRSLRRFSR--TPMFTADALQR-----------FRSYNRPG
MAB_4025c|M.abscessus_ATCC_199 P-----LRLLREARGLFG--GPLFKG-IVGD-----------VRKYLRPG
Mb2799c|M.bovis_AF2122/97 K-----PRWRDYFKAARRGLVPGLPRLLRV------------VGHYYKPG
Rv2777c|M.tuberculosis_H37Rv K-----PRWRDYFKAARRGLVPGLPRLLRV------------VGHYYKPG
MUL_2157|M.ulcerans_Agy99 K-----PRWRDYVRSARRGLTPGPWRLIRV------------VGDYYKPG
MAV_3671|M.avium_104 K-----PRWRDYFRAAWRGLVPGPLRFVRA------------VANYYRPG
MSMEG_3675|M.smegmatis_MC2_155 W-----KMHRLRMRDSKLGLLPKFSTLFGTN-----------TLAYCRPS
TH_1630|M.thermoresistible__bu DTSTIIPLYRLVHRTRKDPDMPGVRPALHPVPWRQKLLTAWRVLGSQTPM
: *
Mflv_4629|M.gilvum_PYR-GCK FHPDDWDSAEILERWTKELFDADGGQQLRSNV-
Mvan_0314|M.vanbaalenii_PYR-1 FHPDDWDSAEILECWTKELFDADGRQQARSSV-
MMAR_3143|M.marinum_M FHPDDWDSTAVLERWSKELFDQDGSQKVIAQPG
MAB_4025c|M.abscessus_ATCC_199 FHPDDINTDELLERWQQELFGSKGILVDHLK--
Mb2799c|M.bovis_AF2122/97 FHPSQLGGLGAAVDYLAVSPAARASH-------
Rv2777c|M.tuberculosis_H37Rv FHPSQLGGLGAAVDYLAVSPAARASH-------
MUL_2157|M.ulcerans_Agy99 FHPSQLGGLERAVDYLAVSPAARASH-------
MAV_3671|M.avium_104 FHPSQLGGLQRAVDYLAVSPAARASH-------
MSMEG_3675|M.smegmatis_MC2_155 FTPDQMGSTAQAVAYLASSPAARAAHL------
TH_1630|M.thermoresistible__bu HNPAHAVIPAFADDWIARYDRGDDVSHGYTS--
. * . :