For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AVVEQGRRGVAARALPKVRRMNFRFGEPAPMKKHYVEGDIVFSHLVSLLSGAFPPGEESFIRSVRNYSDQ ITDPVLKKRVAGFIGQEAMHGREHRKLNEKIVDMGYPLVRIMNFDEGSRREKFVIALEKRAPKIAHLAMT AAAEHYTAVLAQRVLSSPELQEIPMSEEIHHLLNWHAMEEMEHKSVAFDVYRSVGGPESIRIGVMSLIWL GTLPFMTLAVLASILTDPSGWKPLAVLRQAVDVYRGPLVKGLMRDIAEYMRPGFHPDDIDTEELLHEWQG ILFGADGELNDRLPGRRAVGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2967c | - | - | 100% (302) | hypothetical protein MAB_2967c |
| M. abscessus ATCC 19977 | MAB_1116 | - | 3e-80 | 51.70% (294) | hypothetical protein MAB_1116 |
| M. abscessus ATCC 19977 | MAB_4451c | - | 1e-77 | 53.22% (295) | hypothetical protein MAB_4451c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 1e-25 | 32.14% (252) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_4629 | - | 1e-55 | 44.09% (279) | metal-dependent hydrolase |
| M. tuberculosis H37Rv | Rv2777c | - | 1e-25 | 32.14% (252) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3143 | - | 2e-54 | 41.32% (288) | hypothetical protein MMAR_3143 |
| M. avium 104 | MAV_3671 | - | 2e-20 | 28.52% (263) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3675 | - | 3e-16 | 29.03% (248) | metal-dependent hydrolase |
| M. thermoresistible (build 8) | TH_2221 | - | 6e-14 | 27.45% (255) | metal-dependent hydrolase |
| M. ulcerans Agy99 | MUL_2157 | - | 8e-24 | 32.55% (255) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_0314 | - | 1e-55 | 44.01% (284) | metal-dependent hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_3671|M.avium_104 --------------------------------------------------
MSMEG_3675|M.smegmatis_MC2_155 --------------------------------------------------
TH_2221|M.thermoresistible__bu --------------------------------------------------
Mflv_4629|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0314|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3143|M.marinum_M --------------------------------------------------
MAB_2967c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLP---FHYVPNE
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLP---FHYVPNE
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLP---FHYVPNE
MAV_3671|M.avium_104 -MVIIDNQAAGPHDAS---VDHERLVLEARDVDFDWAQLP---FHYAPGE
MSMEG_3675|M.smegmatis_MC2_155 -MLRPLRFDH--------EIDPGPVQIQARKVHFDLSDIP---LHWIPGH
TH_2221|M.thermoresistible__bu -MLRPRRFAT--------EVDPGPVQIQARQVHFDVSGIP---LHWIPGH
Mflv_4629|M.gilvum_PYR-GCK ---MSDDSSTR---------PTTRVVPKPRRVRFDMPAET-SRQHFVDGD
Mvan_0314|M.vanbaalenii_PYR-1 ---MSDDSSTR---------PTTRVVPKPRRVRFDMPAGT-SRQHFVDGD
MMAR_3143|M.marinum_M ---MPEDRAS----------TKSRVLPKPRRVRFPMPTST-KRRHFVDGD
MAB_2967c|M.abscessus_ATCC_199 -MAVVEQGRRG---------VAARALPKVRRMNFRFGEPAPMKKHYVEGD
: * : * . *: ..
Mb2799c|M.bovis_AF2122/97 PMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAM
Rv2777c|M.tuberculosis_H37Rv PMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAM
MUL_2157|M.ulcerans_Agy99 PLPTHVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAM
MAV_3671|M.avium_104 PFATHVLNVLHLLLPAGEQFFVEVFKQALPLIRDDQLRLDVQGFIGQEGV
MSMEG_3675|M.smegmatis_MC2_155 PVASTMVNLFNVVLPVAEHWFVDTFNEALPYVRDPKLADDMRGFIGQEAT
TH_2221|M.thermoresistible__bu PVASNLISLLNVVLPDAERWFVATFNEALPYVKDPKLADDMRGFIGQEAT
Mflv_4629|M.gilvum_PYR-GCK LVMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEAT
Mvan_0314|M.vanbaalenii_PYR-1 LVMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEAT
MMAR_3143|M.marinum_M LVMSHFISVLSATFPEGEDFFIRSVKYFQSSIDDPQLLTAVKGFIGQEAT
MAB_2967c|M.abscessus_ATCC_199 IVFSHLVSLLSGAFPPGEESFIRSVRNYSDQITDPVLKKRVAGFIGQEAM
. : .:. : :* .* *: .. : * * : ***.**.
Mb2799c|M.bovis_AF2122/97 HSQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWL
Rv2777c|M.tuberculosis_H37Rv HSQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWL
MUL_2157|M.ulcerans_Agy99 HSQAHSGVLAHFE-AQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWL
MAV_3671|M.avium_104 HSRAHANVLAHFA-ARGIDLRPYTGQIEWLFGTLLGPRPNWSPRRRQSWL
MSMEG_3675|M.smegmatis_MC2_155 HAETHDKVLEEFLTAHDVHYQPILELVDHVFNTMLAPKPATDPRRRLNDL
TH_2221|M.thermoresistible__bu HADVHEQVMYDFMVEHGVNPEPILAQIEYMFTKVLTPSTSSDPKRRFNNL
Mflv_4629|M.gilvum_PYR-GCK HRHQHRLLNDRLQAMGYPTEGID-----RHIKKLVGRLEKRFSP------
Mvan_0314|M.vanbaalenii_PYR-1 HRHQHRLLNDRLQAMGYPTEGID-----RHIKKLVGRLEKRFSP------
MMAR_3143|M.marinum_M HRHQHRLLNERLQAMGYPTARID-----RHVARLIKRLERRFSP------
MAB_2967c|M.abscessus_ATCC_199 HGREHRKLNEKIVDMGYPLVRIMNFDEGSRREKFVIALEKRAPK------
* * : : .: .
Mb2799c|M.bovis_AF2122/97 LEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEH
Rv2777c|M.tuberculosis_H37Rv LEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEH
MUL_2157|M.ulcerans_Agy99 LEQVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEH
MAV_3671|M.avium_104 LEQISLVSAIEHYTAILGEWILDSPAHDRIGTDPVMLDMLRWHGAEEVEH
MSMEG_3675|M.smegmatis_MC2_155 CDRLWLIAAIEHYTAVLGDFVLN-CAWDDHHADPTLTDLFRWHGAEEVEH
TH_2221|M.thermoresistible__bu CERLWLIAALEHYTAVLGDFALN-CRWDDHGAHPTMVDLYRWHGAEEVEH
Mflv_4629|M.gilvum_PYR-GCK KMRLAVTAALEHYTATFAEIILTSDEAQELIGYTEVRPILLWHALEECEH
Mvan_0314|M.vanbaalenii_PYR-1 RMRLAVTAALEHYTATFAEIILTSDEAQELIGDTEVRPILLWHALEECEH
MMAR_3143|M.marinum_M EMRLSMTSALEHYTATLAEIILTSDDAQKLIGQTEVRPILLWHAFEESEH
MAB_2967c|M.abscessus_ATCC_199 IAHLAMTAAAEHYTAVLAQRVLSSPELQEIPMSEEIHHLLNWHAMEEMEH
:: . :* ***** :.: * : : : **. ** **
Mb2799c|M.bovis_AF2122/97 KAVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPG
Rv2777c|M.tuberculosis_H37Rv KAVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPG
MUL_2157|M.ulcerans_Agy99 KAVAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPG
MAV_3671|M.avium_104 KAVAFDTMKHLRAGYWRQVRTQLVVTPAMLLLWIRGVRFMYSRDPYLPPH
MSMEG_3675|M.smegmatis_MC2_155 RSVAHDVAVYFQDSYLARVRAMTIAATAVYMFFQRGTWAMIRKDPTVDIG
TH_2221|M.thermoresistible__bu RNVAHDVAVYFRDSYVDRIRAMCIAMPLMWAFFERGMWYLVKTDPSVELS
Mflv_4629|M.gilvum_PYR-GCK KAVAFDVYETVGGSERTRVWGMRIASLLLFTELVIQTTRSLAGD----RA
Mvan_0314|M.vanbaalenii_PYR-1 KAVAFDVYETVGGSERTRVWGMRIASLLLFSELVIQTTRSLAGD----RA
MMAR_3143|M.marinum_M KAVAFDAYRLIGGTERTRVRGMRIASAILFGELILQTALSMASD----KA
MAB_2967c|M.abscessus_ATCC_199 KSVAFDVYRSVGGPESIRIGVMSLIWLGTLPFMTLAVLASILTD----PS
: **.*. . :: *
Mb2799c|M.bovis_AF2122/97 TKPRWRDYFKAARRGLVPGLPRLLRV-VGHYYKPGFHPSQLGGLGAAVDY
Rv2777c|M.tuberculosis_H37Rv TKPRWRDYFKAARRGLVPGLPRLLRV-VGHYYKPGFHPSQLGGLGAAVDY
MUL_2157|M.ulcerans_Agy99 TKPRWRDYVRSARRGLTPGPWRLIRV-VGDYYKPGFHPSQLGGLERAVDY
MAV_3671|M.avium_104 TKPRWRDYFRAAWRGLVPGPLRFVRA-VANYYRPGFHPSQLGGLQRAVDY
MSMEG_3675|M.smegmatis_MC2_155 WWKMHRLRMRDSKLGLLPKFSTLFGTNTLAYCRPSFTPDQMGSTAQAVAY
TH_2221|M.thermoresistible__bu WWQTQRQRCRDSGLGLLPKWRTLFFTNTLDYFRPGFTPEQMGSTAQAVAY
Mflv_4629|M.gilvum_PYR-GCK AYNPVRLLRSLRAFRHNPLFSRAAIERFRSYTHAGFHPDDWDSAEILERW
Mvan_0314|M.vanbaalenii_PYR-1 AYNPVRLLRSLRAFRHNPLFSSAAIERFRSYSRGGFHPDDWDSAEILECW
MMAR_3143|M.marinum_M SYNPVTLVRSLRRFSRTPMFTADALQRFRSYNRPGFHPDDWDSTAVLERW
MAB_2967c|M.abscessus_ATCC_199 GWKPLAVLRQAVDVYRGPLVKG-LMRDIAEYMRPGFHPDDIDTEELLHEW
* * : .* *.: . :
Mb2799c|M.bovis_AF2122/97 LAVSPAARASH------------
Rv2777c|M.tuberculosis_H37Rv LAVSPAARASH------------
MUL_2157|M.ulcerans_Agy99 LAVSPAARASH------------
MAV_3671|M.avium_104 LAVSPAARASH------------
MSMEG_3675|M.smegmatis_MC2_155 LASSPAARAAHL-----------
TH_2221|M.thermoresistible__bu LASSPAARSARL-----------
Mflv_4629|M.gilvum_PYR-GCK TKELFDADGGQ----QLRSNV--
Mvan_0314|M.vanbaalenii_PYR-1 TKELFDADGRQ----QARSSV--
MMAR_3143|M.marinum_M SKELFDQDGSQ----KVIAQPG-
MAB_2967c|M.abscessus_ATCC_199 QGILFGADGELNDRLPGRRAVGQ
.