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MNPAADRHIDALVIGAGIAGISAAWHITHHCPSLNVAVLEGRSEIGGTWSLFRYPGVRCDSDMYTLGFSF APWTGKEAIVEGAAILRYLKDVVEQENLDRLIRFDHRVREARWSSQTSLWTLRVDTPAGEQTITCSFLMV CTGYYRYDGGYLPEFSGIDDFPGPVVHPQEWPDDLVIAGKRVALIGSGATAMTLAPRLADTADHVSVVQR SPSYVISRPQRDRFANLLLRWLPRTVALPVIRAKNISLMTFSLYLARRVPQRMGDAIVDRAKRELPPGYD SEKHFRPRYKIWDNRLCLILDGDLFQSIGRGDLTMVTGEIERFTGEGLLLTSGEHIPADIVVAATGFHMR LFGGIEFYRDDEPIDFSSTVCYKGMMLDGIPNFAFTVGYQAATYTLKADIVSRYVSRLLGYLFENGIASV TPHLEDSSVDLEPFTGYRPGYVQRVLADLPRQGSKPPWRLSMNYYRDMWMARAQPVEDANLHFSRNSTVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3967 | - | - | 100% (490) | monooxygenase EthA, flavin-binding |
| M. abscessus ATCC 19977 | MAB_0103 | - | e-137 | 46.79% (483) | monooxygenase EthA |
| M. abscessus ATCC 19977 | MAB_0985 | - | e-124 | 45.34% (483) | putative monooxygenase EthA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3884c | ethA | 1e-146 | 48.85% (479) | monooxygenase ETHA |
| M. gilvum PYR-GCK | Mflv_0962 | - | 1e-136 | 47.71% (480) | monooxygenase, flavin-binding family protein |
| M. tuberculosis H37Rv | Rv3854c | ethA | 1e-146 | 48.85% (479) | monooxygenase ETHA |
| M. leprae Br4923 | MLBr_00065 | - | 1e-140 | 47.53% (486) | putative monooxygenase |
| M. marinum M | MMAR_5404 | ethA | 1e-142 | 48.23% (479) | monooxygenase EthA |
| M. avium 104 | MAV_0175 | - | 1e-133 | 48.50% (466) | monooxygenase, flavin-binding family protein |
| M. smegmatis MC2 155 | MSMEG_6440 | - | 1e-137 | 46.88% (480) | monooxygenase, flavin-binding family protein |
| M. thermoresistible (build 8) | TH_1149 | - | 1e-133 | 50.22% (452) | MONOOXYGENASE ETHA |
| M. ulcerans Agy99 | MUL_5026 | ethA | 1e-141 | 47.81% (479) | monooxygenase EthA |
| M. vanbaalenii PYR-1 | Mvan_5683 | - | 1e-132 | 46.76% (479) | hypothetical protein Mvan_5683 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1149|M.thermoresistible__bu ---VVMTEHLDVLIVGAGISGISAAWHLQDRCPSKSYAILERRDNLGGTW
Mvan_5683|M.vanbaalenii_PYR-1 -----MTEFVDVVIVGAGISGISAAWHLQDRCPGKSYVILERRDNLGGTW
Mflv_0962|M.gilvum_PYR-GCK -----MSDHFDVVIVGAGISGISTAWHLQQRCPDKSYVILERRENIGGTW
MSMEG_6440|M.smegmatis_MC2_155 -----MTEHFDVVIVGAGISGISTAWHLQDRCPTKSYVILERRANIGGTW
MAV_0175|M.avium_104 ---------------------MSAAWHLQNRCPTKSYAILERRADLGGTW
Mb3884c|M.bovis_AF2122/97 -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
Rv3854c|M.tuberculosis_H37Rv -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRESMGGTW
MMAR_5404|M.marinum_M -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MUL_5026|M.ulcerans_Agy99 -----MTEHLDVVIVGAGISGVSAAWHLQDRCPTKSYAILEKRAAMGGTW
MLBr_00065|M.leprae_Br4923 MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGGTW
MAB_3967|M.abscessus_ATCC_1997 -MNPAADRHIDALVIGAGIAGISAAWHITHHCPSLNVAVLEGRSEIGGTW
:*:***: .:** . .:** * :****
TH_1149|M.thermoresistible__bu DLFKYPGIRSDSDMFTLGFRFKPWTDPKAIADGPDILAYLKETAEEFGID
Mvan_5683|M.vanbaalenii_PYR-1 DLFKYPGIRSDSDMFTLGFRFKPWTSDKAIADGPDIMAYLNETVAEYGID
Mflv_0962|M.gilvum_PYR-GCK DLFKYPGIRSDSDMFTLGFRFKPWPSARSIADGPSIWNYINEAAQENGID
MSMEG_6440|M.smegmatis_MC2_155 DLFKYPGIRSDSDMFTLGFRFKPWTSAKSIADGPSIWNYINEAAQENGID
MAV_0175|M.avium_104 DLFKYPGIRSDSDMFTLGFRFKPWRSAKSIADGASIKAYIKEAAVENRIE
Mb3884c|M.bovis_AF2122/97 DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
Rv3854c|M.tuberculosis_H37Rv DLFRYPGIRSDSDMYTLGFRFRPWTGRQAIADGKPILEYVKSTAAMYGID
MMAR_5404|M.marinum_M DLFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MUL_5026|M.ulcerans_Agy99 ELFRYPGIRSDSDMHTLGFRFRPWTERQAIADGKPILEYVKGTAAMYGID
MLBr_00065|M.leprae_Br4923 DLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKPILEYIKSTAVMHGID
MAB_3967|M.abscessus_ATCC_1997 SLFRYPGVRCDSDMYTLGFSFAPWTGKEAIVEGAAILRYLKDVVEQENLD
.**:***:*.****.**** * ** .:*.:* * *:: .. ::
TH_1149|M.thermoresistible__bu EHIRYRHRVVSANWSDPDNKWILQVERDGEQVEMTCSFLFACSGYYNYDE
Mvan_5683|M.vanbaalenii_PYR-1 KHIRYGQNVKSADWSDADNRWTVRVDRAGEEVEISARYLMACSGYYNYDE
Mflv_0962|M.gilvum_PYR-GCK KHIRVKHQVLAANWSDAENRWELTVDHDGEQKQITCSFLSVCSGYYNYDQ
MSMEG_6440|M.smegmatis_MC2_155 KHIRTNHRVLGADWSDAENRWTITVEADGEQKQITASFLSVCSGYYNYDQ
MAV_0175|M.avium_104 PHIRYRHRVVAADWSDADNRWTVTVEHDGQRSEITCSFLFACTGYYNYDE
Mb3884c|M.bovis_AF2122/97 RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
Rv3854c|M.tuberculosis_H37Rv RHIRFHHKVISADWSTAENRWTVHIQSHGTLSALTCEFLFLCSGYYNYDE
MMAR_5404|M.marinum_M KHIRLNQKVISADWSNAQNRWTLQIESNGATSAVTCSFLFLCSGYYNYDQ
MUL_5026|M.ulcerans_Agy99 KHIRLNQKVISADWSNAQNRWTLQIESNGAMSAVTCSFLFLCSGYYNYDQ
MLBr_00065|M.leprae_Br4923 KYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGYYNYEQ
MAB_3967|M.abscessus_ATCC_1997 RLIRFDHRVREARWSSQTSLWTLRVDTPAGEQTITCSFLMVCTGYYRYDG
** :.* * ** . * : :: . ::. :* *:***.*:
TH_1149|M.thermoresistible__bu GYSPEFPGADDFEGTIVHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
Mvan_5683|M.vanbaalenii_PYR-1 GYSPDFPGSEDFEGTLIHPQHWPEDLDYAGKRIVVIGSGATAVTLIPALA
Mflv_0962|M.gilvum_PYR-GCK GYSPEFPGADDFAGQIIHPQHWPEDLDYTGKRIVVIGSGATAVTLIPSLV
MSMEG_6440|M.smegmatis_MC2_155 GYSPEFPGADDFAGQIIHPQHWPEDLDYAGKKIVVIGSGATAVTLIPSLV
MAV_0175|M.avium_104 GYSPTFPGAEDFGGTIVHPQHWPEDLDYAGKRIVVIGSGATAITLIPALV
Mb3884c|M.bovis_AF2122/97 GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
Rv3854c|M.tuberculosis_H37Rv GYSPRFAGSEDFVGPIIHPQHWPEDLDYDAKNIVVIGSGATAVTLVPALA
MMAR_5404|M.marinum_M GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGATAVTLVPALA
MUL_5026|M.ulcerans_Agy99 GYTPNFAGAQDFAGSIIHPQHWPEDLDYDGKNVVVIGSGASAVTLVPALA
MLBr_00065|M.leprae_Br4923 GYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTLVPALA
MAB_3967|M.abscessus_ATCC_1997 GYLPEFSGIDDFPGPVVHPQEWPDDLVIAGKRVALIGSGATAMTLAPRLA
** * * * :** * ::***.**:** .*.:.:*****:*:** * *.
TH_1149|M.thermoresistible__bu ETGAGHVTMLQRSPTYIGSLPLVDPIAVKVNKYLPPKMASVVNRWKAIIF
Mvan_5683|M.vanbaalenii_PYR-1 NSGAGHVTMLQRSPTFIAALPDVDPFTVATNKRLPAKVAYVLNRWKSILQ
Mflv_0962|M.gilvum_PYR-GCK AGGAGHVTMLQRSPTYIGSLPLVDPIAEKANKYLPGSLAHFVNRWKAISF
MSMEG_6440|M.smegmatis_MC2_155 NGGAAHVTMLQRSPTYIGSLPLVDPVAEKTNKYLPKNLAHFVNRWKAIAF
MAV_0175|M.avium_104 NSGAGHVTMLQRSPTYIGSLPGVDPFAERANRLLPDRLAHMANRWKAIAF
Mb3884c|M.bovis_AF2122/97 DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
Rv3854c|M.tuberculosis_H37Rv DSGAKHVTMLQRSPTYIVSQPDRDGIAEKLNRWLPETMAYTAVRWKNVLR
MMAR_5404|M.marinum_M NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MUL_5026|M.ulcerans_Agy99 NSGAKHVTMLQRSPTYIVSQPERDSIAERLNRWLPENMAYAMVRWKNVLR
MLBr_00065|M.leprae_Br4923 NSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRWKNILR
MAB_3967|M.abscessus_ATCC_1997 DT-ADHVSVVQRSPSYVISRPQRDRFANLLLRWLPRTVALPVIRAKNISL
* **:::****::: : * * .: : ** * * * :
TH_1149|M.thermoresistible__bu STFQYQLSRKFPNYMRRTLMRMAERRLPPGYDVEKHFGPRYNPWDERLCL
Mvan_5683|M.vanbaalenii_PYR-1 QSVQYQVARKFPDFFRKQLLTMAKHRLPEGYDVNKHFNPRYNPWDERVCL
Mflv_0962|M.gilvum_PYR-GCK STLQYQLSQRFPKYMRKTLMTMAQRRLPEGYDVEKHFGPRYNPWDERLCL
MSMEG_6440|M.smegmatis_MC2_155 STAQYQLARKFPNYMRKTLMTMAQRRLPEGFDVQKHFGPRYNPWDERLCL
MAV_0175|M.avium_104 STFQYQLSRKAPAYMRKTLMTMAKRRLPEGYDVEKHFGPRYNVWDERLCL
Mb3884c|M.bovis_AF2122/97 QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
Rv3854c|M.tuberculosis_H37Rv QAAVYSACQKWPRRMRKMFLSLIQRQLPEGYDVRKHFGPHYNPWDQRLCL
MMAR_5404|M.marinum_M QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MUL_5026|M.ulcerans_Agy99 QAAVYGACRKWPRRMRKNFMGLAQRQLPEGYDVRKHFGPHYNPWDQRLCL
MLBr_00065|M.leprae_Br4923 QSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFGPHYNPWEQRLCL
MAB_3967|M.abscessus_ATCC_1997 MTFSLYLARRVPQRMGDAIVDRAKRELPPGYDSEKHFRPRYKIWDNRLCL
: .:: * : :: :.** *:* .*** *:*: *::*:**
TH_1149|M.thermoresistible__bu APNGDLFRAIRHGKADVVTDTIDTFTKTGIRLTSGTELEADIIITATGLN
Mvan_5683|M.vanbaalenii_PYR-1 APNGDLFKTIRAGKADVVTDTIERFTKTGIQLASGRHLDADIIVTATGLN
Mflv_0962|M.gilvum_PYR-GCK APNGDLFKTIRAGKADVVTDTIDRFTETGIRLNSGEELAADIIITATGLN
MSMEG_6440|M.smegmatis_MC2_155 APNGDLFKTIRAGKADVVTDTIAKFTETGIKLTSGEELTADIIITATGLN
MAV_0175|M.avium_104 APDGDFFRTIRHGKADVVTDTIDRFTTTGIRLNSGEELPADIIVTATGLN
Mb3884c|M.bovis_AF2122/97 VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
Rv3854c|M.tuberculosis_H37Rv VPNGDLFRAIRHGKVEVVTDTIERFTATGIRLNSGRELPADIIITATGLN
MMAR_5404|M.marinum_M VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MUL_5026|M.ulcerans_Agy99 VPNGDLFRAIRHGQVDVVTDTIDRFTPTGIRLNSGQQLPADIIVTATGLN
MLBr_00065|M.leprae_Br4923 VPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSGNELRADIIVTATGLN
MAB_3967|M.abscessus_ATCC_1997 ILDGDLFQSIGRGDLTMVTGEIERFTGEGLLLTSGEHIPADIVVAATGFH
:**:*::* * :**. * ** *: * ** .: ***:::***::
TH_1149|M.thermoresistible__bu LQLFGGAEIKRNGQPVELTETMAYKGMMLSGMPNMAFTIGYTNASWTLKA
Mvan_5683|M.vanbaalenii_PYR-1 LQLFGGATISRNGEAIELNDTMAYKGMLLTDMPNLAFTIGYTNASWTLKA
Mflv_0962|M.gilvum_PYR-GCK MQLFGGATATRNGEPIDLTKTMTYKGLMLSGVPNMAITFGYTNASWTLKA
MSMEG_6440|M.smegmatis_MC2_155 MQLFGGASLTRNGQEVDLTETMTYKGLMLSGVPNMAITFGYTNASWTLKA
MAV_0175|M.avium_104 MQLLGGVTPTRNGDPVDLTSLMTYKGLMFSGMPNFAITFGYTNASWTLKA
Mb3884c|M.bovis_AF2122/97 LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
Rv3854c|M.tuberculosis_H37Rv LQLFGGATATIDGQQVDITTTMAYKGMMLSGIPNMAYTVGYTNASWTLKA
MMAR_5404|M.marinum_M LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MUL_5026|M.ulcerans_Agy99 LQLFGGAAVTVDGESVDLTKAMAYKGMMLSGLPNMAYTVGYTNASWTLKA
MLBr_00065|M.leprae_Br4923 LQLFGGAVATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVGYTNASWTLKA
MAB_3967|M.abscessus_ATCC_1997 MRLFGGIEFYRDDEPIDFSSTVCYKGMMLDGIPNFAFTVGYQAATYTLKA
::*:** :.: ::: : ***::: .:**: *.** *::****
TH_1149|M.thermoresistible__bu DLVSEFVCRVLNHMDEHGYDVVEPQHPGDSVEERPLLDFTPGYVLRALDR
Mvan_5683|M.vanbaalenii_PYR-1 DLVSEFFCRIINYMDANSYDRVEPRHPGSSVDERPLMDFTPGYVLRALDY
Mflv_0962|M.gilvum_PYR-GCK DLVSEFICRLLNYMDDNGFDRVEAQHPGDSVEEKPFMDFSPGYFRRAMDT
MSMEG_6440|M.smegmatis_MC2_155 DLVSEFICRVLNYMDDNGFDRVEPQHPGDAVDALPFMDFNPGYFRRAMDS
MAV_0175|M.avium_104 DLVSEFVCRLLNYMDAKGFDFVEPQHPGEDVDALPFMDFTPGYFRRSMHL
Mb3884c|M.bovis_AF2122/97 DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
Rv3854c|M.tuberculosis_H37Rv DLVSEFVCRLLNYMDDNGFDTVVVERPGSDVEERPFMEFTPGYVLRSLDE
MMAR_5404|M.marinum_M DLVSEFVCRLLNYMDANDYDSVVVERPGSDVQECPFMEFTPGYVLRVIDE
MUL_5026|M.ulcerans_Agy99 DLVSEFVCRLLNYMDANDYESVVVERPGSDVQECPFMEFTPGYVLRVIDE
MLBr_00065|M.leprae_Br4923 DLVSEFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDA
MAB_3967|M.abscessus_ATCC_1997 DIVSRYVSRLLGYLFENGIASVTPHLEDSSVDLEPFTGYRPGYVQRVLAD
*:**.:..*::.:: :. * . .. *: *: : ***. * :
TH_1149|M.thermoresistible__bu LPPPXXXRMWWTRCRRSRFAAGPPAWRSTTRRRSSRPRPGRWGSTGCG-
Mvan_5683|M.vanbaalenii_PYR-1 LPKAG-SRAPW-RLKQNYLMDLQLIRRGKVDDEALAFSRHPAQVTASA-
Mflv_0962|M.gilvum_PYR-GCK LPKSG-SEAPW-RLKQNYFIDLRTIRYGKVDEESLRFTKHGAPVALSS-
MSMEG_6440|M.smegmatis_MC2_155 LPKSG-SRAPW-RLKQNYFFDLRMIRYDKVDEESLHFTKHRAAVSASSS
MAV_0175|M.avium_104 LPKSG-SRAPW-RLKQNYFFDMRTIRRGRVDDEGLKFAKKRAPVAV---
Mb3884c|M.bovis_AF2122/97 LPKQG-SRTPW-RLNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV---
Rv3854c|M.tuberculosis_H37Rv LPKQG-SRTPW-RLNQNYLRDIRLIRRGKIDDEGLRFAKRPAPVGV---
MMAR_5404|M.marinum_M LPKQG-SRKPW-RLNQNYLRDIHLIRRGKIDDEGLRFAKKPVAVPV---
MUL_5026|M.ulcerans_Agy99 LPKQG-SRKPW-RLNQDYLRDIHLIRRGKIDDEGLRFAKKPVAVPV---
MLBr_00065|M.leprae_Br4923 LPKQG-SRTPW-RLNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV---
MAB_3967|M.abscessus_ATCC_1997 LPRQG-SKPPW-RLSMNYYRDMWMARAQPVEDANLHFSRNSTVS-----
** . * * .