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TAFPYPQLDEEKESEYELFPINLTRMMLHTQGQTVPYLHYALSFRHAKITAQLRERVIVRVGAVAGCEYQ LVQHKSEALRTGTTPELLAGLTDPEHREFGDESLTALVGYVDSLVAHVGAEESARDELRKHFPDNEVAEI TLLASTYVLCASFLKSLGVQPDDGPVDWSTVDAHITAGRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3567c | - | - | 100% (181) | putative carboxymuconolactone decarboxylase |
| M. abscessus ATCC 19977 | MAB_2021c | - | 3e-27 | 39.35% (155) | putative carboxymuconolactone decarboxylase |
| M. abscessus ATCC 19977 | MAB_4488c | - | 3e-11 | 27.33% (161) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1558 | - | 4e-08 | 28.00% (125) | hypothetical protein Mb1558 |
| M. gilvum PYR-GCK | Mflv_2440 | - | 1e-06 | 22.41% (116) | carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv1531 | - | 4e-08 | 28.00% (125) | hypothetical protein Rv1531 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2345 | - | 1e-08 | 30.16% (126) | hypothetical protein MMAR_2345 |
| M. avium 104 | MAV_3238 | pcaC | 2e-09 | 28.80% (125) | hypothetical protein MAV_3238 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3878 | - | 1e-07 | 25.35% (142) | PUTATIVE Carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_4533 | - | 2e-05 | 24.86% (173) | hypothetical protein MUL_4533 |
| M. vanbaalenii PYR-1 | Mvan_4181 | - | 1e-07 | 26.06% (142) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1558|M.bovis_AF2122/97 ---MTTSRVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLNHPRLA
Rv1531|M.tuberculosis_H37Rv ---MTTSRVPLLPVDEAKAAADEAGVPDYMAELS----IFQVLLNHPRLA
MMAR_2345|M.marinum_M ---MTIPRVPLLPVNEAKAAADEAGVPNYMAELS----IFQALLNHPRLA
MAV_3238|M.avium_104 ---MPTARLPKLPLDEAKAAADEAAVPNYMAELS----IFQVLLNHPPLA
TH_3878|M.thermoresistible__bu --VTRLSPLPAEEWTDEVRRSLAPLLAPDRANPRDAGNVLATLVRHPALT
Mvan_4181|M.vanbaalenii_PYR-1 -----MSPLPTEEWDDEVLDALAPLLPPSRSNPRDAGNVLATLVRHPALT
Mflv_2440|M.gilvum_PYR-GCK ---MRVAPLPADQWDDTVDKALSGLMPEEMRNPETAGNLVATLVRHPRLA
MUL_4533|M.ulcerans_Agy99 MTGDQVARIPSGGIRQLGPVNWALAKLAARSVRAPEMHLFTALGYRQYLF
MAB_3567c|M.abscessus_ATCC_199 -----MTAFPYPQLDEEKESEYELFPIN----------LTRMMLHTQGQT
. .* : : :
Mb1558|M.bovis_AF2122/97 RTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVASGLGV
Rv1531|M.tuberculosis_H37Rv RTFNDLLATMLWHGTLDSRLRELVIMRIGWLTDCDYEWTQHWRVASGLGV
MMAR_2345|M.marinum_M RTFNDLLATMLWHGALDPRLRELVIMRIGWLTACDYEWTQHWRVASGLGV
MAV_3238|M.avium_104 RAINDLLATMLWHGALDSRLRELIIMRIGWLTGCDYEWTQHWRVASRLGV
TH_3878|M.thermoresistible__bu RAYLEFNAYLLRDSTLSTRTREVAVLRVVLLRDCEYLWEHHIPLAQRAGL
Mvan_4181|M.vanbaalenii_PYR-1 RAYLHFNAHLLLASTLSPRIREVALLRAVHVRRSDYLWEHHIPIAQRAGI
Mflv_2440|M.gilvum_PYR-GCK KGFLRFNFHLLYGSSLPARLRELAVLRIAHLTKCEYEWLHHVEMGREAGL
MUL_4533|M.ulcerans_Agy99 WTWAIYSGRLLHG-RLPRIDTELVILRVAHLRSCEYELQHHRRMARAAGL
MAB_3567c|M.abscessus_ATCC_199 VPYLHY-ALSFRHAKITAQLRERVIVRVGAVAGCEYQLVQHKSEALRTGT
: : * ::* : .:* :* . *
Mb1558|M.bovis_AF2122/97 SADDLLGVRDW-------QGYNGFGPAEQAVLAATDDVVREGAVSAQSWS
Rv1531|M.tuberculosis_H37Rv SADDLLGVRDW-------QGYNGFGPAEQAVLAATDDVVREGAVSAQSWS
MMAR_2345|M.marinum_M SAQDLLGVRDW-------RQYNGFGPTERAVLAATDDIVRDGAVSASSWA
MAV_3238|M.avium_104 PGDDLLGVRDW-------RNYPGFGPTERAVLAATDDVVRHGSVSAASWA
TH_3878|M.thermoresistible__bu TPAEIVGIRNG-------RMADEP---DQLVVRAADELARDHEISEGTWR
Mvan_4181|M.vanbaalenii_PYR-1 TPDEIDAIRQG-------RPADEI---DRLVVGAVDELDAANTVSDATWS
Mflv_2440|M.gilvum_PYR-GCK SDDVIDGITRG-------EATDGL---DRAVLNAVDELQNDSVVSDATWT
MUL_4533|M.ulcerans_Agy99 DAHAQATIFAWPDAPQGDGPRRVLSSRQQALLTATDELIKNRSVTPATWE
MAB_3567c|M.abscessus_ATCC_199 TPELLAGLTDP-------EHREFGDESLTALVGYVDSLVAHVGAEESARD
: :: .*.: :
Mb1558|M.bovis_AF2122/97 ACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWPPDGLS
Rv1531|M.tuberculosis_H37Rv ACERELHCDKVVLIELVTVISAWRMVASILHSLEVPLEDGVSSWPPDGLS
MMAR_2345|M.marinum_M ECERELHGDVTVLTELVTAISAWCMVASILHSLKVPLEDGVASWPPDGCS
MAV_3238|M.avium_104 QCEHEFKRDTTVLVELVTVIGAWRMVASILQSLEVPLEDGVASWPPDGRE
TH_3878|M.thermoresistible__bu ALG--RHFDDRGRMDLVFTVGCYALLAVAVNTFGVEPEHA----------
Mvan_4181|M.vanbaalenii_PYR-1 ALR--DHFDERQVLDLIFTVGCYQLLGAAVNTLGVQPEPH----------
Mflv_2440|M.gilvum_PYR-GCK ALS--DHLDERQLMDLVFTIGCYGALAMAINTFGVEPDQER---------
MUL_4533|M.ulcerans_Agy99 QLE--IHLNRRRLIEFCLLATQYDALAATITALGVPLDNPR---------
MAB_3567c|M.abscessus_ATCC_199 ELR--KHFPDNEVAEITLLASTYVLCASFLKSLGVQPDDGPVDWSTVDAH
: :: : . : :: * :
Mb1558|M.bovis_AF2122/97 PR----
Rv1531|M.tuberculosis_H37Rv PR----
MMAR_2345|M.marinum_M P-----
MAV_3238|M.avium_104 PAS---
TH_3878|M.thermoresistible__bu ------
Mvan_4181|M.vanbaalenii_PYR-1 ------
Mflv_2440|M.gilvum_PYR-GCK ------
MUL_4533|M.ulcerans_Agy99 ------
MAB_3567c|M.abscessus_ATCC_199 ITAGRL