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MAEEPVPRGRIRRTMPLAGFTARAAGGRLVAGLREKAGDTGAVDRFHHRTAERYTELLGHSKGVLMKAGQ IFSSIDMNGADGGISPYEQALTRLQTQSPPMAPALARSVLESELRVPTSQAYASFTDDPISAASIGQVHR ATLHDGRDVVVKIQYPGVAQAIQDDLANTELVTTFLRVTFALLDRRYAIDLPATARDISAQIKEELDYKQ EAENISAFHRLFAGHPFIRVPQAVPELSTRRVLTMTYVDGIDWTEAQQADQELKNTWAEALWRFSLAPLQ HACAFYTDLHPGNYRFGLDGSLGIVDFGSVKNLRESHRLAWIRMVAASIQQRPADLHSTMKEAGFLAAHS SMSADEALRWMNEINADATLPQPVTYTPQLIDRNLTALDSSLSRRISLPPELIYLVRFPLGVRSAMSKLG ATVSSRSAAADMIGIAEPDTALGIRHVAWVKERGLPFGLDPREQSEVGARL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3314 | - | - | 100% (471) | hypothetical protein MAB_3314 |
| M. abscessus ATCC 19977 | MAB_3315 | - | e-146 | 54.98% (462) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2969 | - | 2e-52 | 30.77% (455) | putative ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3220 | - | 8e-43 | 29.75% (447) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4658 | - | 4e-41 | 27.23% (448) | hypothetical protein Mflv_4658 |
| M. tuberculosis H37Rv | Rv3197 | - | 8e-43 | 29.75% (447) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00640 | - | 6e-42 | 27.74% (447) | hypothetical protein MLBr_00640 |
| M. marinum M | MMAR_1443 | - | 1e-137 | 52.79% (466) | hypothetical protein MMAR_1443 |
| M. avium 104 | MAV_4141 | - | 2e-44 | 28.95% (456) | ABC1 family protein |
| M. smegmatis MC2 155 | MSMEG_1954 | - | 3e-38 | 26.46% (446) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_1133 | - | 7e-45 | 29.37% (446) | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. ulcerans Agy99 | MUL_2510 | - | 1e-45 | 29.65% (452) | ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_1810 | - | 3e-42 | 28.10% (452) | hypothetical protein Mvan_1810 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1954|M.smegmatis_MC2_155 ----------------------------------MSDIKRGSVARNAKLA
TH_1133|M.thermoresistible__bu -----------------------------VDDGVVADIKRGRVSRNAKLA
Mb3220|M.bovis_AF2122/97 -----------------------------MDDGSVSDIKRGRAARNAKLA
Rv3197|M.tuberculosis_H37Rv -----------------------------MDDGSVSDIKRGRAARNAKLA
MUL_2510|M.ulcerans_Agy99 -----------------------------MDDGGVSDIKRGRAARNAKLA
MAV_4141|M.avium_104 ----------------------------------MSDIKRGRAARNAKLA
MLBr_00640|M.leprae_Br4923 MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLA
Mflv_4658|M.gilvum_PYR-GCK -----------------------------MDDGLVSEIKRGSVARNAKLA
Mvan_1810|M.vanbaalenii_PYR-1 -----------------------------MDDGLVSDIKRGRAARNAKLA
MAB_3314|M.abscessus_ATCC_1997 --------------------------------MAEEPVPRGRIRRTMPLA
MMAR_1443|M.marinum_M ---------------------------------MHDSLPCGRIRRAMPLA
: * * **
MSMEG_1954|M.smegmatis_MC2_155 GLAGGMAGRAALGFGKRLTGKSKDEVTAELMDKAAQQLFTVLGELKGGAM
TH_1133|M.thermoresistible__bu GLGAGLAGRAALGLGKRLTGKSKDEVNAELMDKAAQQLFQVLGELKGGAM
Mb3220|M.bovis_AF2122/97 SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
Rv3197|M.tuberculosis_H37Rv SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
MUL_2510|M.ulcerans_Agy99 SIPVGFAGRAALGVGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGGAM
MAV_4141|M.avium_104 SIPVGFAGRAAIGFGKRLTGKSRDEVQAELLEKAANQLFTVLGELKGGAM
MLBr_00640|M.leprae_Br4923 SIPVGLAGRAVLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAM
Mflv_4658|M.gilvum_PYR-GCK SLPVGMAGRAALGFGKRLTGKSKDEVNAEMMDKAAQQLFTVLGELKGGAM
Mvan_1810|M.vanbaalenii_PYR-1 SLPVGMAGRAALGFGKRLTGKSKDEVNAELMDKAAQQLFTVLGELKGGAM
MAB_3314|M.abscessus_ATCC_1997 GFTARAAGGRLVAGLREKAGDTG--AVDRFHHRTAERYTELLGHSKGVLM
MMAR_1443|M.marinum_M GFTARAAGGRMVAALQEKAGDTG--AVGRFHARIAERYAELLGHSKGVSM
.: ** :. :. :*.: . .: : *.: :**. ** *
MSMEG_1954|M.smegmatis_MC2_155 KVGQALSVMEAAIPEQYGKP-YREALTKLQKDAPPLPAAKVHRVLDAQLG
TH_1133|M.thermoresistible__bu KVGQALSVMEAAVPEQYGKP-YREALTKLQKDAPPLPASRVHRVLDQQLG
Mb3220|M.bovis_AF2122/97 KVGQALSVMEAAIPDEFGEP-YREALTKLQKDAPPLPASKVHRVLDGQLG
Rv3197|M.tuberculosis_H37Rv KVGQALSVMEAAIPDEFGEP-YREALTKLQKDAPPLPASKVHRVLDGQLG
MUL_2510|M.ulcerans_Agy99 KVGQALSVMEAAIPEQFGEP-YREALTKLQKDAPPLPAAKVHRVLDAQLG
MAV_4141|M.avium_104 KVGQALSVLEAAVPEEFGEP-YREALTKLQKDAPPLPAAKVHRVLDAQLG
MLBr_00640|M.leprae_Br4923 KVGQALSVMEAAIPEEYGEP-YREALTKLQKDAPPLPVNKVHRVLDAQLG
Mflv_4658|M.gilvum_PYR-GCK KVGQALSVMEAAIPEQYGKP-YREALTKLQREAPPLPAAKVHRVLDQQLG
Mvan_1810|M.vanbaalenii_PYR-1 KVGQALSVMEAAIPEQYGKP-YREALTKLQREAPPLPAPKVHRVLDQQLG
MAB_3314|M.abscessus_ATCC_1997 KAGQIFSSIDMNGAD-GGISPYEQALTRLQTQSPPMAPALARSVLESELR
MMAR_1443|M.marinum_M KAGQMLSMLDASSIGSGGFSPYQKALTRLQADAPPMDPAVATAVLRADLG
*.** :* :: * . *.:***:** ::**: . ** :*
MSMEG_1954|M.smegmatis_MC2_155 TKWRDRFSSFDDKPVASASIGQVHKGIWSDGREVAVKIQYPGADEALRAD
TH_1133|M.thermoresistible__bu TRWRDRFRSFDDRPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRAD
Mb3220|M.bovis_AF2122/97 TKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRAD
Rv3197|M.tuberculosis_H37Rv TKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRAD
MUL_2510|M.ulcerans_Agy99 TKWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALKAD
MAV_4141|M.avium_104 TKWRERFSSFDDTPVASASIGQVHKGVWSDGREVAVKIQYPGADEALRAD
MLBr_00640|M.leprae_Br4923 TKWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRAD
Mflv_4658|M.gilvum_PYR-GCK TKWRERFQTFDDKAVASASIGQVHKAVWADGREVAVKIQYPGADEALRAD
Mvan_1810|M.vanbaalenii_PYR-1 TKWRERFASFDDTAVASASIGQVHKAVWSDGREVAVKIQYPGADEALRAD
MAB_3314|M.abscessus_ATCC_1997 VPTSQAYASFTDDPISAASIGQVHRATLHDGRDVVVKIQYPGVAQAIQDD
MMAR_1443|M.marinum_M RPVGEVFAQFTDEPIAAASIGQVHRAVLHDGRQVAVKIQYPGAARAIRDD
: : * * .:::*******:. **:*.*******. .*:: *
MSMEG_1954|M.smegmatis_MC2_155 LK------TIQRLVGVFKQLAPGADIQGVVDELTERTEMELDYRLEADNQ
TH_1133|M.thermoresistible__bu LK------TMQRMVGILKQLSPGADVEGVVEELIERTEMELDYRLEADHQ
Mb3220|M.bovis_AF2122/97 LK------TMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQ
Rv3197|M.tuberculosis_H37Rv LK------TMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQ
MUL_2510|M.ulcerans_Agy99 LK------TMQRMLGVFKQLSPGADVQGVVDELIERTEMELDYRLEADNQ
MAV_4141|M.avium_104 LK------TMQRLVGVFKQLAPGADVQGVVDELIERTEMELDYRLEAENQ
MLBr_00640|M.leprae_Br4923 LK------TMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEADNQ
Mflv_4658|M.gilvum_PYR-GCK LK------TMQRMVGVLKQLSPGADVQGVVDELIERTEMELDYRLEADNQ
Mvan_1810|M.vanbaalenii_PYR-1 LK------TMQRLVGVLKQLSPGADVQGVVDELIERTEMELDYRLEADNQ
MAB_3314|M.abscessus_ATCC_1997 LANTELVTTFLRVTFALLDRRYAIDLPATARDISAQIKEELDYKQEAENI
MMAR_1443|M.marinum_M LANAELLATFFRFATSAAGTTMQPDLRQAARELSARIAEETDYQHEAVNI
* *: *. *: .. :: : * **: ** :
MSMEG_1954|M.smegmatis_MC2_155 RAFAKAYRNDPHFAVPAIIASAP--KVVISEWMEGIPMSVIIREGTPEQR
TH_1133|M.thermoresistible__bu RAFAKAYRDHPHFAVPQVIASAP--KVVIAEWIDGIPMSQIIRDGTQEQR
Mb3220|M.bovis_AF2122/97 RAFAKAYHDHPRFQVPHVVASAP--KVVIQEWIEGVPMAEIIRHGTTEQR
Rv3197|M.tuberculosis_H37Rv RAFAKAYHDHPRFQVPHVVASAP--KVVIQEWIEGVPMAEIIRHGTTEQR
MUL_2510|M.ulcerans_Agy99 RAFAKAYAGHPRFLVPHIVASAP--KVVIQEWIDGVPMSQIIRNGTQQER
MAV_4141|M.avium_104 RAFAKAYQDHPHFAVPRIVASAP--KVVIQEWMQGIPMAEIIRHGTTEQR
MLBr_00640|M.leprae_Br4923 RAFAKAYQGDPRFVVPNVVASAP--KVIIQEWIDGVPMAEIIRNGTAQQR
Mflv_4658|M.gilvum_PYR-GCK RAFAKAYAGHPEFVVPRVVASAP--KVVIQEWIEGIPLSHIIREGTQEQR
Mvan_1810|M.vanbaalenii_PYR-1 RAFAKAYAGDPHFVVPHVVASAP--KVVIQEWIEGIPLSHIIRDGTQEQR
MAB_3314|M.abscessus_ATCC_1997 SAFHRLFAGHPFIRVPQAVPELSTRRVLTMTYVDGIDWTEAQQA-DQELK
MMAR_1443|M.marinum_M TTFGELYRGHPFIRVPEVIDDASNDRVLTMTYLEGLDWSAAQRA-DQDLK
:* . : ..* : ** : . . :*: :::*: : : : :
MSMEG_1954|M.smegmatis_MC2_155 DLMGTRLTELTFGAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLP
TH_1133|M.thermoresistible__bu DVMATRLTELTYDAPSRLEMMHGDAHPGNFMLLSDGRMGVIDFGAVAPLP
Mb3220|M.bovis_AF2122/97 DLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMP
Rv3197|M.tuberculosis_H37Rv DLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMP
MUL_2510|M.ulcerans_Agy99 DLMGTLLLELTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAPMP
MAV_4141|M.avium_104 DLMGTRLLELTFDAPRRLGMLHGDAHPGNFMLLPDGRMGVIDFGAVAPLP
MLBr_00640|M.leprae_Br4923 DRMGKLLLELTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLP
Mflv_4658|M.gilvum_PYR-GCK DLMATRLFEFCDDAPTRLEMVHGDAHPGNFMLLPGDKMGVIDFGAVAPMP
Mvan_1810|M.vanbaalenii_PYR-1 DLMATRLFEFCDDAPTRLEMVHGDAHPGNFMLMPDDKMGVIDFGAVAPMP
MAB_3314|M.abscessus_ATCC_1997 NTWAEALWRFSLAPLQHACAFYTDLHPGNYRFGLDGSLGIVDFGSVKNLR
MMAR_1443|M.marinum_M NTWAEVIVRFVMGSFRHANLFHADPHPANFCFGADGTVGFVDFGSVAAVP
: . : .: . : .: * **.*: : .. :*.:***:: :
MSMEG_1954|M.smegmatis_MC2_155 GGFPTSLGETIRLARDKNYDELLPTMERAGFLQKGQEVSIEEVEDMLRQY
TH_1133|M.thermoresistible__bu GGFPIELGLMLRYALEKDYDNLIATMEKAGFIQPGGEVSIREIDEMLRQY
Mb3220|M.bovis_AF2122/97 GGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQY
Rv3197|M.tuberculosis_H37Rv GGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQY
MUL_2510|M.ulcerans_Agy99 GGYPIELGMTIRLARDKNYDLLLPTMEKAGLIQRGQQVSVREIDEMLRQY
MAV_4141|M.avium_104 DGLPVELGMTIRLARDKNYDLLLPTMEKAGFIQKGQQVSVRDIDDMLRQY
MLBr_00640|M.leprae_Br4923 GGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQY
Mflv_4658|M.gilvum_PYR-GCK GGWPIELGQMLRYAVDKNYDKLLPTMEKVGFIQKGQTVSTREIDDMLKQY
Mvan_1810|M.vanbaalenii_PYR-1 GGWPVELGQILRYAVDKNYEKLLPTMEKAGFIQKGQRPSTREIDDMLKQY
MAB_3314|M.abscessus_ATCC_1997 ESHRLAWIRMVAASIQQRPADLHSTMKEAGFLAAHSSMSADEALRWMNEI
MMAR_1443|M.marinum_M ECQRRNKVANVRATLDGRKRDVRELLVNMGFIARDSTLTADEAYAWMTEL
: : : : : . *:: : : : :
MSMEG_1954|M.smegmatis_MC2_155 VDPIKVDVFHYNRKWLQKMAASQMDNSVAQIKMARSLDLPANLAIPLRVI
TH_1133|M.thermoresistible__bu VEPVEVDVFHFNRKWLQRLTAVDMDRSVAQIKTARQMDLPRHLAIPMRVI
Mb3220|M.bovis_AF2122/97 VEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVI
Rv3197|M.tuberculosis_H37Rv VEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVI
MUL_2510|M.ulcerans_Agy99 VEPIQVEVFHYTRRWLQRMTVSQIDRSVAQIKAARQMDLPPKLAIPMRVI
MAV_4141|M.avium_104 VEPVEVEVFHYTRKWLQKMSAIEIDRSVSQIRTARQMDLPPKLVIPMRVI
MLBr_00640|M.leprae_Br4923 VEPIKVEVFHYTRKWLQQIS---LDRSVSHIKTARQLDLPATLALPMRVI
Mflv_4658|M.gilvum_PYR-GCK VEPLEVEVFHYTRRWLQKMTNIELEKAAGQIKAARQMDIPPKLAIPMRVI
Mvan_1810|M.vanbaalenii_PYR-1 VEPLEVPVFHYTRRWLQKMTAIELDKAAGQIKAARQMDIPPKLAIPMRVI
MAB_3314|M.abscessus_ATCC_1997 NADATLPQPVTYTPQLIDRNLTALDSSLS-----RRISLPPELIYLVRFP
MMAR_1443|M.marinum_M VYELLVPQPVTYTHVASLRAIRALIDIRPPSHPFRRMSIPDDSVLFSRIN
: : * :.:* *.
MSMEG_1954|M.smegmatis_MC2_155 ASTVAICCQLDAHVPVKVIATELVPGFAEEAA------------------
TH_1133|M.thermoresistible__bu ASVVAISCQLDARVPVKALALEMIPGFAVEAA------------------
Mb3220|M.bovis_AF2122/97 ASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV---------------
Rv3197|M.tuberculosis_H37Rv ASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV---------------
MUL_2510|M.ulcerans_Agy99 ASVAAILCQLDAHVPIKALSEELIPGFAEPDTAAV---------------
MAV_4141|M.avium_104 MSVAAILCQLDAHVPIKALSEELVPGFAEPDNAVV---------------
MLBr_00640|M.leprae_Br4923 ASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV---------------
Mflv_4658|M.gilvum_PYR-GCK ASIVAISCQLDAHVPTRRIAMENVPGFADPDGV-----------------
Mvan_1810|M.vanbaalenii_PYR-1 ASIVAISCQLDAHVDTRRIAMEKVPGFADPDAV-----------------
MAB_3314|M.abscessus_ATCC_1997 LGVRSAMSKLGATVSSRSAAADMIG-IAEPDTALGIRHVAWVKERGLPFG
MMAR_1443|M.marinum_M LSMTAILAALGATIHARAIFDDMDG-VAEPITQLGKQHAAWVRKRGLPWG
. : . *.* : : . .*
MSMEG_1954|M.smegmatis_MC2_155 -------------
TH_1133|M.thermoresistible__bu -------------
Mb3220|M.bovis_AF2122/97 -------------
Rv3197|M.tuberculosis_H37Rv -------------
MUL_2510|M.ulcerans_Agy99 -------------
MAV_4141|M.avium_104 -------------
MLBr_00640|M.leprae_Br4923 -------------
Mflv_4658|M.gilvum_PYR-GCK -------------
Mvan_1810|M.vanbaalenii_PYR-1 -------------
MAB_3314|M.abscessus_ATCC_1997 LDPREQSEVGARL
MMAR_1443|M.marinum_M LDDHDHR------