For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSDRVPLARINRGRALGKLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTVLGSLKGSAMK LGQLLSMLEVDMVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESNLGALSKNFRDFDETPVAAASIGQ VYRAVLLDGREVAVKVKYPGVDEAVRADMQNLALFTKFWRKALPTLSNSAFMDEISMNLESELDYPREAR TQHEIAERYRGHPFIVVPDCVPELCTSQILVTEFLDGQAFPYMQTLPEDERNRIGELIFRFYIGSLFQDN DFCGDPHPGNILLAADGTVGFVDFGLYNRMNPEHVDFERHIMRAATEGRAQDMYDAMVARGIIDPQAGVS PQDCLEYCHAASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQNLPPEHIFSRRADFYTFGVLG QLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2969 | - | - | 100% (456) | putative ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4045c | - | 5e-89 | 39.33% (445) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3504 | - | 2e-58 | 34.54% (443) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3220 | - | 6e-45 | 36.69% (308) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4658 | - | 1e-42 | 34.88% (301) | hypothetical protein Mflv_4658 |
| M. tuberculosis H37Rv | Rv3197 | - | 6e-45 | 36.69% (308) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00640 | - | 3e-47 | 34.86% (370) | hypothetical protein MLBr_00640 |
| M. marinum M | MMAR_1443 | - | 4e-55 | 31.37% (459) | hypothetical protein MMAR_1443 |
| M. avium 104 | MAV_4141 | - | 6e-47 | 32.32% (427) | ABC1 family protein |
| M. smegmatis MC2 155 | MSMEG_1954 | - | 7e-45 | 35.31% (303) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_1133 | - | 3e-46 | 34.86% (350) | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. ulcerans Agy99 | MUL_2510 | - | 1e-47 | 32.13% (442) | ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_1810 | - | 3e-44 | 31.01% (445) | hypothetical protein Mvan_1810 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1954|M.smegmatis_MC2_155 ----------------------------------MSDIKRGSVARNAKLA
TH_1133|M.thermoresistible__bu -----------------------------VDDGVVADIKRGRVSRNAKLA
Mflv_4658|M.gilvum_PYR-GCK -----------------------------MDDGLVSEIKRGSVARNAKLA
Mvan_1810|M.vanbaalenii_PYR-1 -----------------------------MDDGLVSDIKRGRAARNAKLA
Mb3220|M.bovis_AF2122/97 -----------------------------MDDGSVSDIKRGRAARNAKLA
Rv3197|M.tuberculosis_H37Rv -----------------------------MDDGSVSDIKRGRAARNAKLA
MUL_2510|M.ulcerans_Agy99 -----------------------------MDDGGVSDIKRGRAARNAKLA
MAV_4141|M.avium_104 ----------------------------------MSDIKRGRAARNAKLA
MLBr_00640|M.leprae_Br4923 MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLA
MAB_2969|M.abscessus_ATCC_1997 ---------------------------------MSDRVPLARINRGRALG
MMAR_1443|M.marinum_M ---------------------------------MHDSLPCGRIRRAMPL-
: . * *
MSMEG_1954|M.smegmatis_MC2_155 GLAGGMAGRAALG--FGKRLTGKSKDEVTAELMDKAAQQLFTVLGELKGG
TH_1133|M.thermoresistible__bu GLGAGLAGRAALG--LGKRLTGKSKDEVNAELMDKAAQQLFQVLGELKGG
Mflv_4658|M.gilvum_PYR-GCK SLPVGMAGRAALG--FGKRLTGKSKDEVNAEMMDKAAQQLFTVLGELKGG
Mvan_1810|M.vanbaalenii_PYR-1 SLPVGMAGRAALG--FGKRLTGKSKDEVNAELMDKAAQQLFTVLGELKGG
Mb3220|M.bovis_AF2122/97 SIPVGFAGRAALG--LGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGG
Rv3197|M.tuberculosis_H37Rv SIPVGFAGRAALG--LGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGG
MUL_2510|M.ulcerans_Agy99 SIPVGFAGRAALG--VGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGG
MAV_4141|M.avium_104 SIPVGFAGRAAIG--FGKRLTGKSRDEVQAELLEKAANQLFTVLGELKGG
MLBr_00640|M.leprae_Br4923 SIPVGLAGRAVLG--LGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGG
MAB_2969|M.abscessus_ATCC_1997 KLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTVLGSLKGS
MMAR_1443|M.marinum_M ---AGFTARAAGGRMVAALQEKAGDTGAVGRFHARIAERYAELLGHSKGV
* : *:. . . . : *.: :** **
MSMEG_1954|M.smegmatis_MC2_155 AMKVGQALSVMEA-AIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQ
TH_1133|M.thermoresistible__bu AMKVGQALSVMEA-AVPEQYGKPYREALTKLQKDAPPLPASRVHRVLDQQ
Mflv_4658|M.gilvum_PYR-GCK AMKVGQALSVMEA-AIPEQYGKPYREALTKLQREAPPLPAAKVHRVLDQQ
Mvan_1810|M.vanbaalenii_PYR-1 AMKVGQALSVMEA-AIPEQYGKPYREALTKLQREAPPLPAPKVHRVLDQQ
Mb3220|M.bovis_AF2122/97 AMKVGQALSVMEA-AIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQ
Rv3197|M.tuberculosis_H37Rv AMKVGQALSVMEA-AIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQ
MUL_2510|M.ulcerans_Agy99 AMKVGQALSVMEA-AIPEQFGEPYREALTKLQKDAPPLPAAKVHRVLDAQ
MAV_4141|M.avium_104 AMKVGQALSVLEA-AVPEEFGEPYREALTKLQKDAPPLPAAKVHRVLDAQ
MLBr_00640|M.leprae_Br4923 AMKVGQALSVMEA-AIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQ
MAB_2969|M.abscessus_ATCC_1997 AMKLGQLLSMLEVDMVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESN
MMAR_1443|M.marinum_M SMKAGQMLSMLDASSIGSGGFSPYQKALTRLQADAPPMDPAVATAVLRAD
:** ** **:::. : . . ::: *::*: :** :: :
MSMEG_1954|M.smegmatis_MC2_155 LGTKWRDRFSSFDDKPVASASIGQVHKGIWSDGREVAVKIQYPGADEALR
TH_1133|M.thermoresistible__bu LGTRWRDRFRSFDDRPVASASIGQVHKAIWSDGREVAVKIQYPGADEALR
Mflv_4658|M.gilvum_PYR-GCK LGTKWRERFQTFDDKAVASASIGQVHKAVWADGREVAVKIQYPGADEALR
Mvan_1810|M.vanbaalenii_PYR-1 LGTKWRERFASFDDTAVASASIGQVHKAVWSDGREVAVKIQYPGADEALR
Mb3220|M.bovis_AF2122/97 LGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALR
Rv3197|M.tuberculosis_H37Rv LGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALR
MUL_2510|M.ulcerans_Agy99 LGTKWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALK
MAV_4141|M.avium_104 LGTKWRERFSSFDDTPVASASIGQVHKGVWSDGREVAVKIQYPGADEALR
MLBr_00640|M.leprae_Br4923 LGTKWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALR
MAB_2969|M.abscessus_ATCC_1997 LG-ALSKNFRDFDETPVAAASIGQVYRAVLLDGREVAVKVKYPGVDEAVR
MMAR_1443|M.marinum_M LGRPVGEVFAQFTDEPIAAASIGQVHRAVLHDGRQVAVKIQYPGAARAIR
** . * * : .:*:******::.: **:****::***. .*::
MSMEG_1954|M.smegmatis_MC2_155 ADLKTIQRLVGVFKQLAPGADIQG------VVDELTERTEMELDYRLEAD
TH_1133|M.thermoresistible__bu ADLKTMQRMVGILKQLSPGADVEG------VVEELIERTEMELDYRLEAD
Mflv_4658|M.gilvum_PYR-GCK ADLKTMQRMVGVLKQLSPGADVQG------VVDELIERTEMELDYRLEAD
Mvan_1810|M.vanbaalenii_PYR-1 ADLKTMQRLVGVLKQLSPGADVQG------VVDELIERTEMELDYRLEAD
Mb3220|M.bovis_AF2122/97 ADLKTMQRMVGVLKQLSPGADVQG------VVDELVERTEMELDYRLEAA
Rv3197|M.tuberculosis_H37Rv ADLKTMQRMVGVLKQLSPGADVQG------VVDELVERTEMELDYRLEAA
MUL_2510|M.ulcerans_Agy99 ADLKTMQRMLGVFKQLSPGADVQG------VVDELIERTEMELDYRLEAD
MAV_4141|M.avium_104 ADLKTMQRLVGVFKQLAPGADVQG------VVDELIERTEMELDYRLEAE
MLBr_00640|M.leprae_Br4923 ADLKTMQRMVGILKQLSPGADIQG------VVDELVERTEMELDYRLEAD
MAB_2969|M.abscessus_ATCC_1997 ADMQNLALFTKFWRKALPTLSN------SAFMDEISMNLESELDYPREAR
MMAR_1443|M.marinum_M DDLANAELLATFFRFATSAAGTTMQPDLRQAARELSARIAEETDYQHEAV
*: . : . : . . *: . * ** **
MSMEG_1954|M.smegmatis_MC2_155 NQRAFAKAYRNDPHFAVPAIIASAP--KVVISEWMEGIPMSVIIREGTPE
TH_1133|M.thermoresistible__bu HQRAFAKAYRDHPHFAVPQVIASAP--KVVIAEWIDGIPMSQIIRDGTQE
Mflv_4658|M.gilvum_PYR-GCK NQRAFAKAYAGHPEFVVPRVVASAP--KVVIQEWIEGIPLSHIIREGTQE
Mvan_1810|M.vanbaalenii_PYR-1 NQRAFAKAYAGDPHFVVPHVVASAP--KVVIQEWIEGIPLSHIIRDGTQE
Mb3220|M.bovis_AF2122/97 NQRAFAKAYHDHPRFQVPHVVASAP--KVVIQEWIEGVPMAEIIRHGTTE
Rv3197|M.tuberculosis_H37Rv NQRAFAKAYHDHPRFQVPHVVASAP--KVVIQEWIEGVPMAEIIRHGTTE
MUL_2510|M.ulcerans_Agy99 NQRAFAKAYAGHPRFLVPHIVASAP--KVVIQEWIDGVPMSQIIRNGTQQ
MAV_4141|M.avium_104 NQRAFAKAYQDHPHFAVPRIVASAP--KVVIQEWMQGIPMAEIIRHGTTE
MLBr_00640|M.leprae_Br4923 NQRAFAKAYQGDPRFVVPNVVASAP--KVIIQEWIDGVPMAEIIRNGTAQ
MAB_2969|M.abscessus_ATCC_1997 TQHEIAERYRGHPFIVVPDCVPELCTSQILVTEFLDGQAFPYMQTLPE-D
MMAR_1443|M.marinum_M NITTFGELYRGHPFIRVPEVIDDASNDRVLTMTYLEGLDWSAAQRADQ-D
:.: * ..* : ** : . ::: :::* . :
MSMEG_1954|M.smegmatis_MC2_155 QRDLMGTRLTELTFGAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAP
TH_1133|M.thermoresistible__bu QRDVMATRLTELTYDAPSRLEMMHGDAHPGNFMLLSDGRMGVIDFGAVAP
Mflv_4658|M.gilvum_PYR-GCK QRDLMATRLFEFCDDAPTRLEMVHGDAHPGNFMLLPGDKMGVIDFGAVAP
Mvan_1810|M.vanbaalenii_PYR-1 QRDLMATRLFEFCDDAPTRLEMVHGDAHPGNFMLMPDDKMGVIDFGAVAP
Mb3220|M.bovis_AF2122/97 QRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAP
Rv3197|M.tuberculosis_H37Rv QRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAP
MUL_2510|M.ulcerans_Agy99 ERDLMGTLLLELTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAP
MAV_4141|M.avium_104 QRDLMGTRLLELTFDAPRRLGMLHGDAHPGNFMLLPDGRMGVIDFGAVAP
MLBr_00640|M.leprae_Br4923 QRDRMGKLLLELTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAP
MAB_2969|M.abscessus_ATCC_1997 ERNRIGELIFRFYIGSLFQDNDFCGDPHPGNILLAADGTVGFVDFGLYNR
MMAR_1443|M.marinum_M LKNTWAEVIVRFVMGSFRHANLFHADPHPANFCFGADGTVGFVDFGSVAA
:: . : .: .: : . .*.**.*: : ... :*.:***
MSMEG_1954|M.smegmatis_MC2_155 LPGGFPTSLGETIRLARDKNYDELLPTMERAGFLQKGQEVSIEEVEDMLR
TH_1133|M.thermoresistible__bu LPGGFPIELGLMLRYALEKDYDNLIATMEKAGFIQPGGEVSIREIDEMLR
Mflv_4658|M.gilvum_PYR-GCK MPGGWPIELGQMLRYAVDKNYDKLLPTMEKVGFIQKGQTVSTREIDDMLK
Mvan_1810|M.vanbaalenii_PYR-1 MPGGWPVELGQILRYAVDKNYEKLLPTMEKAGFIQKGQRPSTREIDDMLK
Mb3220|M.bovis_AF2122/97 MPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLR
Rv3197|M.tuberculosis_H37Rv MPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLR
MUL_2510|M.ulcerans_Agy99 MPGGYPIELGMTIRLARDKNYDLLLPTMEKAGLIQRGQQVSVREIDEMLR
MAV_4141|M.avium_104 LPDGLPVELGMTIRLARDKNYDLLLPTMEKAGFIQKGQQVSVRDIDDMLR
MLBr_00640|M.leprae_Br4923 LPGGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMH
MAB_2969|M.abscessus_ATCC_1997 MNPEHVDFERHIMRAATEGRAQDMYDAMVARGIIDPQAGVSPQDCLEYCH
MMAR_1443|M.marinum_M VPECQRRNKVANVRATLDGRKRDVRELLVNMGFIARDSTLTADEAYAWMT
: :* : : : : *:: : :
MSMEG_1954|M.smegmatis_MC2_155 QYVDP-IKVDVFHYNRKWLQKMAASQMDNSVAQIKMARSLDLPANLAIPL
TH_1133|M.thermoresistible__bu QYVEP-VEVDVFHFNRKWLQRLTAVDMDRSVAQIKTARQMDLPRHLAIPM
Mflv_4658|M.gilvum_PYR-GCK QYVEP-LEVEVFHYTRRWLQKMTNIELEKAAGQIKAARQMDIPPKLAIPM
Mvan_1810|M.vanbaalenii_PYR-1 QYVEP-LEVPVFHYTRRWLQKMTAIELDKAAGQIKAARQMDIPPKLAIPM
Mb3220|M.bovis_AF2122/97 QYVEP-IQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPM
Rv3197|M.tuberculosis_H37Rv QYVEP-IQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPM
MUL_2510|M.ulcerans_Agy99 QYVEP-IQVEVFHYTRRWLQRMTVSQIDRSVAQIKAARQMDLPPKLAIPM
MAV_4141|M.avium_104 QYVEP-VEVEVFHYTRKWLQKMSAIEIDRSVSQIRTARQMDLPPKLVIPM
MLBr_00640|M.leprae_Br4923 QYVEP-IKVEVFHYTRKWLQQIS---LDRSVSHIKTARQLDLPATLALPM
MAB_2969|M.abscessus_ATCC_1997 AASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQNLPPEHIFSR
MMAR_1443|M.marinum_M ELVYELLVPQPVTYTHVASLRAIRALIDIRPPSHP-FRRMSIPDDSVLFS
: . . :: * .:* :
MSMEG_1954|M.smegmatis_MC2_155 RVIASTVAICCQLDAHVPVKVIATELVPGFAEEAA---------------
TH_1133|M.thermoresistible__bu RVIASVVAISCQLDARVPVKALALEMIPGFAVEAA---------------
Mflv_4658|M.gilvum_PYR-GCK RVIASIVAISCQLDAHVPTRRIAMENVPGFADPDGV--------------
Mvan_1810|M.vanbaalenii_PYR-1 RVIASIVAISCQLDAHVDTRRIAMEKVPGFADPDAV--------------
Mb3220|M.bovis_AF2122/97 RVIASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV------------
Rv3197|M.tuberculosis_H37Rv RVIASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV------------
MUL_2510|M.ulcerans_Agy99 RVIASVAAILCQLDAHVPIKALSEELIPGFAEPDTAAV------------
MAV_4141|M.avium_104 RVIMSVAAILCQLDAHVPIKALSEELVPGFAEPDNAVV------------
MLBr_00640|M.leprae_Br4923 RVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV------------
MAB_2969|M.abscessus_ATCC_1997 RADFYTFGVLGQLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR---
MMAR_1443|M.marinum_M RINLSMTAILAALGATIHARAIFDDMDGVAEPITQLGKQHAAWVRKRGLP
* .: *.. : : .
MSMEG_1954|M.smegmatis_MC2_155 ---------
TH_1133|M.thermoresistible__bu ---------
Mflv_4658|M.gilvum_PYR-GCK ---------
Mvan_1810|M.vanbaalenii_PYR-1 ---------
Mb3220|M.bovis_AF2122/97 ---------
Rv3197|M.tuberculosis_H37Rv ---------
MUL_2510|M.ulcerans_Agy99 ---------
MAV_4141|M.avium_104 ---------
MLBr_00640|M.leprae_Br4923 ---------
MAB_2969|M.abscessus_ATCC_1997 ---------
MMAR_1443|M.marinum_M WGLDDHDHR