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MRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLASIPVGLAGRAVLGLGKRLTGK SKDEVNTKLIEKTAHQLFSVLGELKGGAMKVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVH RVLDAQLGTKWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADLKTMQRMVGILK QLSPGADIQGVVDELVERTEMELDYRLEADNQRAFAKAYQGDPRFVVPNVVASAPKVIIQEWIDGVPMAE IIRNGTAQQRDRMGKLLLELTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLPGGFPVELGMS IRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVFHYTRKWLQQISLDRSVSHIKT ARQLDLPATLALPMRVIASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00640 | - | - | 100% (473) | hypothetical protein MLBr_00640 |
| M. leprae Br4923 | MLBr_01898 | - | 2e-24 | 29.72% (286) | hypothetical protein MLBr_01898 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3220 | - | 0.0 | 83.00% (447) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4658 | - | 0.0 | 73.59% (443) | hypothetical protein Mflv_4658 |
| M. tuberculosis H37Rv | Rv3197 | - | 0.0 | 83.00% (447) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3503 | - | 1e-152 | 59.38% (448) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_1366 | - | 0.0 | 83.22% (447) | ABC transporter ATP-binding protein |
| M. avium 104 | MAV_4141 | - | 0.0 | 81.45% (442) | ABC1 family protein |
| M. smegmatis MC2 155 | MSMEG_1954 | - | 0.0 | 75.46% (436) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_1133 | - | 0.0 | 75.45% (440) | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. ulcerans Agy99 | MUL_2510 | - | 0.0 | 83.00% (447) | ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_1810 | - | 0.0 | 74.94% (443) | hypothetical protein Mvan_1810 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3220|M.bovis_AF2122/97 -----------------------------MDDGSVSDIKRGRAARNAKLA
Rv3197|M.tuberculosis_H37Rv -----------------------------MDDGSVSDIKRGRAARNAKLA
MMAR_1366|M.marinum_M -----------------------------MDDGGVSDIKRGRAARNAKLA
MUL_2510|M.ulcerans_Agy99 -----------------------------MDDGGVSDIKRGRAARNAKLA
MLBr_00640|M.leprae_Br4923 MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLA
MAV_4141|M.avium_104 ----------------------------------MSDIKRGRAARNAKLA
Mflv_4658|M.gilvum_PYR-GCK -----------------------------MDDGLVSEIKRGSVARNAKLA
Mvan_1810|M.vanbaalenii_PYR-1 -----------------------------MDDGLVSDIKRGRAARNAKLA
MSMEG_1954|M.smegmatis_MC2_155 ----------------------------------MSDIKRGSVARNAKLA
TH_1133|M.thermoresistible__bu -----------------------------VDDGVVADIKRGRVSRNAKLA
MAB_3503|M.abscessus_ATCC_1997 ---------MALTLPEIDEAPLFVNFITSGHDVRMAEIRRGRAARAAKLA
:::*:** .:* ****
Mb3220|M.bovis_AF2122/97 SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
Rv3197|M.tuberculosis_H37Rv SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
MMAR_1366|M.marinum_M SIPVGFAGRAALGVGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGGAM
MUL_2510|M.ulcerans_Agy99 SIPVGFAGRAALGVGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGGAM
MLBr_00640|M.leprae_Br4923 SIPVGLAGRAVLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAM
MAV_4141|M.avium_104 SIPVGFAGRAAIGFGKRLTGKSRDEVQAELLEKAANQLFTVLGELKGGAM
Mflv_4658|M.gilvum_PYR-GCK SLPVGMAGRAALGFGKRLTGKSKDEVNAEMMDKAAQQLFTVLGELKGGAM
Mvan_1810|M.vanbaalenii_PYR-1 SLPVGMAGRAALGFGKRLTGKSKDEVNAELMDKAAQQLFTVLGELKGGAM
MSMEG_1954|M.smegmatis_MC2_155 GLAGGMAGRAALGFGKRLTGKSKDEVTAELMDKAAQQLFTVLGELKGGAM
TH_1133|M.thermoresistible__bu GLGAGLAGRAALGLGKRLTGKSKDEVNAELMDKAAQQLFQVLGELKGGAM
MAB_3503|M.abscessus_ATCC_1997 SLPAGIAGRAALGVGKRLAGKSKDEVNAELVEKAAEQLFQVLGELKGAAM
.: *:****.:*.****:***:*** :::::*:*.*** *******.**
Mb3220|M.bovis_AF2122/97 KVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGT
Rv3197|M.tuberculosis_H37Rv KVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGT
MMAR_1366|M.marinum_M KVGQALSVMEAAIPEQFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
MUL_2510|M.ulcerans_Agy99 KVGQALSVMEAAIPEQFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
MLBr_00640|M.leprae_Br4923 KVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQLGT
MAV_4141|M.avium_104 KVGQALSVLEAAVPEEFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
Mflv_4658|M.gilvum_PYR-GCK KVGQALSVMEAAIPEQYGKPYREALTKLQREAPPLPAAKVHRVLDQQLGT
Mvan_1810|M.vanbaalenii_PYR-1 KVGQALSVMEAAIPEQYGKPYREALTKLQREAPPLPAPKVHRVLDQQLGT
MSMEG_1954|M.smegmatis_MC2_155 KVGQALSVMEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
TH_1133|M.thermoresistible__bu KVGQALSVMEAAVPEQYGKPYREALTKLQKDAPPLPASRVHRVLDQQLGT
MAB_3503|M.abscessus_ATCC_1997 KIGQMLSVMEAAIPPEFGEPYREALTKLQSDAPPLPADKVHRVLDAQLGT
*:** ***:***:* ::*:********** :*****. :****** ****
Mb3220|M.bovis_AF2122/97 KWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADL
Rv3197|M.tuberculosis_H37Rv KWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADL
MMAR_1366|M.marinum_M KWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALKADL
MUL_2510|M.ulcerans_Agy99 KWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALKADL
MLBr_00640|M.leprae_Br4923 KWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADL
MAV_4141|M.avium_104 KWRERFSSFDDTPVASASIGQVHKGVWSDGREVAVKIQYPGADEALRADL
Mflv_4658|M.gilvum_PYR-GCK KWRERFQTFDDKAVASASIGQVHKAVWADGREVAVKIQYPGADEALRADL
Mvan_1810|M.vanbaalenii_PYR-1 KWRERFASFDDTAVASASIGQVHKAVWSDGREVAVKIQYPGADEALRADL
MSMEG_1954|M.smegmatis_MC2_155 KWRDRFSSFDDKPVASASIGQVHKGIWSDGREVAVKIQYPGADEALRADL
TH_1133|M.thermoresistible__bu RWRDRFRSFDDRPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADL
MAB_3503|M.abscessus_ATCC_1997 KWRERFQSFDDKPVASASIGQVHKAVWKDGRVVAVKVQYPGADEAVRSDL
:**:** :*:* .***********.:* ** ****:********:::**
Mb3220|M.bovis_AF2122/97 KTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAY
Rv3197|M.tuberculosis_H37Rv KTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAY
MMAR_1366|M.marinum_M KTMQRMVGVFKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
MUL_2510|M.ulcerans_Agy99 KTMQRMLGVFKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
MLBr_00640|M.leprae_Br4923 KTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEADNQRAFAKAY
MAV_4141|M.avium_104 KTMQRLVGVFKQLAPGADVQGVVDELIERTEMELDYRLEAENQRAFAKAY
Mflv_4658|M.gilvum_PYR-GCK KTMQRMVGVLKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
Mvan_1810|M.vanbaalenii_PYR-1 KTMQRLVGVLKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
MSMEG_1954|M.smegmatis_MC2_155 KTIQRLVGVFKQLAPGADIQGVVDELTERTEMELDYRLEADNQRAFAKAY
TH_1133|M.thermoresistible__bu KTMQRMVGILKQLSPGADVEGVVEELIERTEMELDYRLEADHQRAFAKAY
MAB_3503|M.abscessus_ATCC_1997 KTIQRLSSLFKQVAPGADIKGIVDELIERTEEELDYRIEATNQRAFAKAF
**:**: .::**::****::*:*:** **** *****:** :*******:
Mb3220|M.bovis_AF2122/97 HDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAE
Rv3197|M.tuberculosis_H37Rv HDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAE
MMAR_1366|M.marinum_M AGHPRFLVPHIVASAPKVVIQEWIDGVPMSQIIRNGTQQERDLMGTLLLE
MUL_2510|M.ulcerans_Agy99 AGHPRFLVPHIVASAPKVVIQEWIDGVPMSQIIRNGTQQERDLMGTLLLE
MLBr_00640|M.leprae_Br4923 QGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLE
MAV_4141|M.avium_104 QDHPHFAVPRIVASAPKVVIQEWMQGIPMAEIIRHGTTEQRDLMGTRLLE
Mflv_4658|M.gilvum_PYR-GCK AGHPEFVVPRVVASAPKVVIQEWIEGIPLSHIIREGTQEQRDLMATRLFE
Mvan_1810|M.vanbaalenii_PYR-1 AGDPHFVVPHVVASAPKVVIQEWIEGIPLSHIIRDGTQEQRDLMATRLFE
MSMEG_1954|M.smegmatis_MC2_155 RNDPHFAVPAIIASAPKVVISEWMEGIPMSVIIREGTPEQRDLMGTRLTE
TH_1133|M.thermoresistible__bu RDHPHFAVPQVIASAPKVVIAEWIDGIPMSQIIRDGTQEQRDVMATRLTE
MAB_3503|M.abscessus_ATCC_1997 KGDPEFYVPSVIASSPKVIITEWLQGRKLSEIIASGTEEERSRCAHLLLE
..*.* ** ::**:***:* **::* :: ** ** ::*. . * *
Mb3220|M.bovis_AF2122/97 LTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGM
Rv3197|M.tuberculosis_H37Rv LTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGM
MMAR_1366|M.marinum_M LTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAPMPGGYPIELGM
MUL_2510|M.ulcerans_Agy99 LTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAPMPGGYPIELGM
MLBr_00640|M.leprae_Br4923 LTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLPGGFPVELGM
MAV_4141|M.avium_104 LTFDAPRRLGMLHGDAHPGNFMLLPDGRMGVIDFGAVAPLPDGLPVELGM
Mflv_4658|M.gilvum_PYR-GCK FCDDAPTRLEMVHGDAHPGNFMLLPGDKMGVIDFGAVAPMPGGWPIELGQ
Mvan_1810|M.vanbaalenii_PYR-1 FCDDAPTRLEMVHGDAHPGNFMLMPDDKMGVIDFGAVAPMPGGWPVELGQ
MSMEG_1954|M.smegmatis_MC2_155 LTFGAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLPGGFPTSLGE
TH_1133|M.thermoresistible__bu LTYDAPSRLEMMHGDAHPGNFMLLSDGRMGVIDFGAVAPLPGGFPIELGL
MAB_3503|M.abscessus_ATCC_1997 FSISSPYRCGLLHADTHPGNFMLLEDGRFGVMDFGACASHEGGLPAGFGP
: .:* * ::*.*:*******: ..::*::**** *. .* * :*
Mb3220|M.bovis_AF2122/97 TIRLAREKNYDLLLPTMEKAGLIQR-GRQVSVREIDEMLRQYVEPIQVEV
Rv3197|M.tuberculosis_H37Rv TIRLAREKNYDLLLPTMEKAGLIQR-GRQVSVREIDEMLRQYVEPIQVEV
MMAR_1366|M.marinum_M TIRLARDKNYDLLLPTMEKAGLIQR-GQQVSVREIDEMLRQYVEPIQVEV
MUL_2510|M.ulcerans_Agy99 TIRLARDKNYDLLLPTMEKAGLIQR-GQQVSVREIDEMLRQYVEPIQVEV
MLBr_00640|M.leprae_Br4923 SIRLARDKNYNLLLQTMEKAGLIQK-GRQVSVRDIDEMMHQYVEPIKVEV
MAV_4141|M.avium_104 TIRLARDKNYDLLLPTMEKAGFIQK-GQQVSVRDIDDMLRQYVEPVEVEV
Mflv_4658|M.gilvum_PYR-GCK MLRYAVDKNYDKLLPTMEKVGFIQK-GQTVSTREIDDMLKQYVEPLEVEV
Mvan_1810|M.vanbaalenii_PYR-1 ILRYAVDKNYEKLLPTMEKAGFIQK-GQRPSTREIDDMLKQYVEPLEVPV
MSMEG_1954|M.smegmatis_MC2_155 TIRLARDKNYDELLPTMERAGFLQK-GQEVSIEEVEDMLRQYVDPIKVDV
TH_1133|M.thermoresistible__bu MLRYALEKDYDNLIATMEKAGFIQP-GGEVSIREIDEMLRQYVEPVEVDV
MAB_3503|M.abscessus_ATCC_1997 ILRLARDEKWEELTEVLRSEGFIPPSATSVSHEEVNSYLEPYIEPLNYDT
:* * ::.:: * .:. *:: . * .:::. :. *::*:: .
Mb3220|M.bovis_AF2122/97 FHYTRKWLQKMTVSQIDRSVA----QIRTARQMDLPAKLAIPMRVIASVG
Rv3197|M.tuberculosis_H37Rv FHYTRKWLQKMTVSQIDRSVA----QIRTARQMDLPAKLAIPMRVIASVG
MMAR_1366|M.marinum_M FHYTRRWLQRMTVSQIDRSVA----QIKAARQMDLPPKLAIPMRVIASVA
MUL_2510|M.ulcerans_Agy99 FHYTRRWLQRMTVSQIDRSVA----QIKAARQMDLPPKLAIPMRVIASVA
MLBr_00640|M.leprae_Br4923 FHYTRKWLQQIS---LDRSVS----HIKTARQLDLPATLALPMRVIASVG
MAV_4141|M.avium_104 FHYTRKWLQKMSAIEIDRSVS----QIRTARQMDLPPKLVIPMRVIMSVA
Mflv_4658|M.gilvum_PYR-GCK FHYTRRWLQKMTNIELEKAAG----QIKAARQMDIPPKLAIPMRVIASIV
Mvan_1810|M.vanbaalenii_PYR-1 FHYTRRWLQKMTAIELDKAAG----QIKAARQMDIPPKLAIPMRVIASIV
MSMEG_1954|M.smegmatis_MC2_155 FHYNRKWLQKMAASQMDNSVA----QIKMARSLDLPANLAIPLRVIASTV
TH_1133|M.thermoresistible__bu FHFNRKWLQRLTAVDMDRSVA----QIKTARQMDLPRHLAIPMRVIASVV
MAB_3503|M.abscessus_ATCC_1997 FHFSRKWLQRLTAKATDFRSEEFLESFKTSRQMNLPPNYLMFFRVLGGLI
**:.*:***::: : :: :*.:::* : :**: .
Mb3220|M.bovis_AF2122/97 AILCQLDAHVPIKALSEELIPGFAEPDAIVV--
Rv3197|M.tuberculosis_H37Rv AILCQLDAHVPIKALSEELIPGFAEPDAIVV--
MMAR_1366|M.marinum_M AILCQLDAHVPIKALSEELIPGFAEPDTAAV--
MUL_2510|M.ulcerans_Agy99 AILCQLDAHVPIKALSEELIPGFAEPDTAAV--
MLBr_00640|M.leprae_Br4923 AILCQLDAHVPTKALTEKLVPGFAEPDTAIV--
MAV_4141|M.avium_104 AILCQLDAHVPIKALSEELVPGFAEPDNAVV--
Mflv_4658|M.gilvum_PYR-GCK AISCQLDAHVPTRRIAMENVPGFADPDGV----
Mvan_1810|M.vanbaalenii_PYR-1 AISCQLDAHVDTRRIAMEKVPGFADPDAV----
MSMEG_1954|M.smegmatis_MC2_155 AICCQLDAHVPVKVIATELVPGFAEEAA-----
TH_1133|M.thermoresistible__bu AISCQLDARVPVKALALEMIPGFAVEAA-----
MAB_3503|M.abscessus_ATCC_1997 GIAAQLDAPVDYAAIIDKWVPGFHEDSKAPAAT
.* .**** * : : :***