For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
HDSLPCGRIRRAMPLAGFTARAAGGRMVAALQEKAGDTGAVGRFHARIAERYAELLGHSKGVSMKAGQML SMLDASSIGSGGFSPYQKALTRLQADAPPMDPAVATAVLRADLGRPVGEVFAQFTDEPIAAASIGQVHRA VLHDGRQVAVKIQYPGAARAIRDDLANAELLATFFRFATSAAGTTMQPDLRQAARELSARIAEETDYQHE AVNITTFGELYRGHPFIRVPEVIDDASNDRVLTMTYLEGLDWSAAQRADQDLKNTWAEVIVRFVMGSFRH ANLFHADPHPANFCFGADGTVGFVDFGSVAAVPECQRRNKVANVRATLDGRKRDVRELLVNMGFIARDST LTADEAYAWMTELVYELLVPQPVTYTHVASLRAIRALIDIRPPSHPFRRMSIPDDSVLFSRINLSMTAIL AALGATIHARAIFDDMDGVAEPITQLGKQHAAWVRKRGLPWGLDDHDHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1443 | - | - | 100% (470) | hypothetical protein MMAR_1443 |
| M. marinum M | MMAR_1366 | - | 6e-48 | 31.70% (448) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0982 | - | 1e-22 | 28.39% (317) | hypothetical protein MMAR_0982 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3220 | - | 2e-46 | 31.33% (450) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4658 | - | 4e-44 | 31.11% (450) | hypothetical protein Mflv_4658 |
| M. tuberculosis H37Rv | Rv3197 | - | 2e-46 | 31.33% (450) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00640 | - | 6e-46 | 30.05% (436) | hypothetical protein MLBr_00640 |
| M. abscessus ATCC 19977 | MAB_3315 | - | 1e-168 | 62.58% (465) | putative ABC transporter ATP-binding protein |
| M. avium 104 | MAV_4141 | - | 5e-49 | 31.78% (450) | ABC1 family protein |
| M. smegmatis MC2 155 | MSMEG_1954 | - | 1e-45 | 29.53% (447) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_1133 | - | 1e-45 | 30.61% (441) | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. ulcerans Agy99 | MUL_2510 | - | 5e-48 | 31.70% (448) | ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_1810 | - | 8e-44 | 32.51% (446) | hypothetical protein Mvan_1810 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1954|M.smegmatis_MC2_155 ----------------------------------MSDIKRGSVARNAKLA
TH_1133|M.thermoresistible__bu -----------------------------VDDGVVADIKRGRVSRNAKLA
Mflv_4658|M.gilvum_PYR-GCK -----------------------------MDDGLVSEIKRGSVARNAKLA
Mvan_1810|M.vanbaalenii_PYR-1 -----------------------------MDDGLVSDIKRGRAARNAKLA
Mb3220|M.bovis_AF2122/97 -----------------------------MDDGSVSDIKRGRAARNAKLA
Rv3197|M.tuberculosis_H37Rv -----------------------------MDDGSVSDIKRGRAARNAKLA
MUL_2510|M.ulcerans_Agy99 -----------------------------MDDGGVSDIKRGRAARNAKLA
MAV_4141|M.avium_104 ----------------------------------MSDIKRGRAARNAKLA
MLBr_00640|M.leprae_Br4923 MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLA
MMAR_1443|M.marinum_M --------------------------------MHD-SLPCGRIRRAMPLA
MAB_3315|M.abscessus_ATCC_1997 --------------------------------MSDRHIPRGRIRRTMPLA
: * * **
MSMEG_1954|M.smegmatis_MC2_155 GLAGGMAGRAALGFGKRLTGKSKDEVTAELMDKAAQQLFTVLGELKGGAM
TH_1133|M.thermoresistible__bu GLGAGLAGRAALGLGKRLTGKSKDEVNAELMDKAAQQLFQVLGELKGGAM
Mflv_4658|M.gilvum_PYR-GCK SLPVGMAGRAALGFGKRLTGKSKDEVNAEMMDKAAQQLFTVLGELKGGAM
Mvan_1810|M.vanbaalenii_PYR-1 SLPVGMAGRAALGFGKRLTGKSKDEVNAELMDKAAQQLFTVLGELKGGAM
Mb3220|M.bovis_AF2122/97 SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
Rv3197|M.tuberculosis_H37Rv SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
MUL_2510|M.ulcerans_Agy99 SIPVGFAGRAALGVGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGGAM
MAV_4141|M.avium_104 SIPVGFAGRAAIGFGKRLTGKSRDEVQAELLEKAANQLFTVLGELKGGAM
MLBr_00640|M.leprae_Br4923 SIPVGLAGRAVLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAM
MMAR_1443|M.marinum_M GFTARAAGGRMVAALQEKAGDTG--AVGRFHARIAERYAELLGHSKGVSM
MAB_3315|M.abscessus_ATCC_1997 GFTARAAGGRLVAGLREKAGDTG--AINRFHERTAERYTELLGHSKGVLM
.: ** :. :. :*.: . .: : *.: :**. ** *
MSMEG_1954|M.smegmatis_MC2_155 KVGQALSVMEAAIPEQYG-KPYREALTKLQKDAPPLPAAKVHRVLDAQLG
TH_1133|M.thermoresistible__bu KVGQALSVMEAAVPEQYG-KPYREALTKLQKDAPPLPASRVHRVLDQQLG
Mflv_4658|M.gilvum_PYR-GCK KVGQALSVMEAAIPEQYG-KPYREALTKLQREAPPLPAAKVHRVLDQQLG
Mvan_1810|M.vanbaalenii_PYR-1 KVGQALSVMEAAIPEQYG-KPYREALTKLQREAPPLPAPKVHRVLDQQLG
Mb3220|M.bovis_AF2122/97 KVGQALSVMEAAIPDEFG-EPYREALTKLQKDAPPLPASKVHRVLDGQLG
Rv3197|M.tuberculosis_H37Rv KVGQALSVMEAAIPDEFG-EPYREALTKLQKDAPPLPASKVHRVLDGQLG
MUL_2510|M.ulcerans_Agy99 KVGQALSVMEAAIPEQFG-EPYREALTKLQKDAPPLPAAKVHRVLDAQLG
MAV_4141|M.avium_104 KVGQALSVLEAAVPEEFG-EPYREALTKLQKDAPPLPAAKVHRVLDAQLG
MLBr_00640|M.leprae_Br4923 KVGQALSVMEAAIPEEYG-EPYREALTKLQKDAPPLPVNKVHRVLDAQLG
MMAR_1443|M.marinum_M KAGQMLSMLDASSIGSGGFSPYQKALTRLQADAPPMDPAVATAVLRADLG
MAB_3315|M.abscessus_ATCC_1997 KAGQIFSVADIASHGYAQLTPYQNALTRLQADAPPMHPLLARQALEEDLG
*.** :*: : : **::***:** :***: . .* :**
MSMEG_1954|M.smegmatis_MC2_155 TKWRDRFSSFDDKPVASASIGQVHKGIWSDGREVAVKIQYPGADEALRAD
TH_1133|M.thermoresistible__bu TRWRDRFRSFDDRPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRAD
Mflv_4658|M.gilvum_PYR-GCK TKWRERFQTFDDKAVASASIGQVHKAVWADGREVAVKIQYPGADEALRAD
Mvan_1810|M.vanbaalenii_PYR-1 TKWRERFASFDDTAVASASIGQVHKAVWSDGREVAVKIQYPGADEALRAD
Mb3220|M.bovis_AF2122/97 TKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRAD
Rv3197|M.tuberculosis_H37Rv TKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRAD
MUL_2510|M.ulcerans_Agy99 TKWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALKAD
MAV_4141|M.avium_104 TKWRERFSSFDDTPVASASIGQVHKGVWSDGREVAVKIQYPGADEALRAD
MLBr_00640|M.leprae_Br4923 TKWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRAD
MMAR_1443|M.marinum_M RPVGEVFAQFTDEPIAAASIGQVHRAVLHDGRQVAVKIQYPGAARAIRDD
MAB_3315|M.abscessus_ATCC_1997 RPVEDLFSAFCDDPIAAASIGQVHRATLHDGRQVAVKIQYPGVAQAIRHD
: * * * .:*:*******:. **:*********. .*:: *
MSMEG_1954|M.smegmatis_MC2_155 LKTIQRLVGVFKQLA------PGADIQGVVDELTERTEMELDYRLEADNQ
TH_1133|M.thermoresistible__bu LKTMQRMVGILKQLS------PGADVEGVVEELIERTEMELDYRLEADHQ
Mflv_4658|M.gilvum_PYR-GCK LKTMQRMVGVLKQLS------PGADVQGVVDELIERTEMELDYRLEADNQ
Mvan_1810|M.vanbaalenii_PYR-1 LKTMQRLVGVLKQLS------PGADVQGVVDELIERTEMELDYRLEADNQ
Mb3220|M.bovis_AF2122/97 LKTMQRMVGVLKQLS------PGADVQGVVDELVERTEMELDYRLEAANQ
Rv3197|M.tuberculosis_H37Rv LKTMQRMVGVLKQLS------PGADVQGVVDELVERTEMELDYRLEAANQ
MUL_2510|M.ulcerans_Agy99 LKTMQRMLGVFKQLS------PGADVQGVVDELIERTEMELDYRLEADNQ
MAV_4141|M.avium_104 LKTMQRLVGVFKQLA------PGADVQGVVDELIERTEMELDYRLEAENQ
MLBr_00640|M.leprae_Br4923 LKTMQRMVGILKQLS------PGADIQGVVDELVERTEMELDYRLEADNQ
MMAR_1443|M.marinum_M LANAELLATFFRFATSAAGTTMQPDLRQAARELSARIAEETDYQHEAVNI
MAB_3315|M.abscessus_ATCC_1997 LSNAELMATFLRFATGIAGPKPQLDHRQMADEVAARISEELDYRHEAANI
* . : : .:: : * . . *: * * **: ** :
MSMEG_1954|M.smegmatis_MC2_155 RAFAKAYRNDPHFAVPAIIASAP--KVVISEWMEGIPMSVIIREGTPEQR
TH_1133|M.thermoresistible__bu RAFAKAYRDHPHFAVPQVIASAP--KVVIAEWIDGIPMSQIIRDGTQEQR
Mflv_4658|M.gilvum_PYR-GCK RAFAKAYAGHPEFVVPRVVASAP--KVVIQEWIEGIPLSHIIREGTQEQR
Mvan_1810|M.vanbaalenii_PYR-1 RAFAKAYAGDPHFVVPHVVASAP--KVVIQEWIEGIPLSHIIRDGTQEQR
Mb3220|M.bovis_AF2122/97 RAFAKAYHDHPRFQVPHVVASAP--KVVIQEWIEGVPMAEIIRHGTTEQR
Rv3197|M.tuberculosis_H37Rv RAFAKAYHDHPRFQVPHVVASAP--KVVIQEWIEGVPMAEIIRHGTTEQR
MUL_2510|M.ulcerans_Agy99 RAFAKAYAGHPRFLVPHIVASAP--KVVIQEWIDGVPMSQIIRNGTQQER
MAV_4141|M.avium_104 RAFAKAYQDHPHFAVPRIVASAP--KVVIQEWMQGIPMAEIIRHGTTEQR
MLBr_00640|M.leprae_Br4923 RAFAKAYQGDPRFVVPNVVASAP--KVIIQEWIDGVPMAEIIRNGTAQQR
MMAR_1443|M.marinum_M TTFGELYRGHPFIRVPEVIDDASNDRVLTMTYLEGLDWSAAQRA-DQDLK
MAB_3315|M.abscessus_ATCC_1997 QAFAALYDGHPFIRIPEVISGASGNRVLTMTYLDGLDWTAAQQA-DQDLK
:*. * ..* : :* :: .*. :*: :::*: : : : :
MSMEG_1954|M.smegmatis_MC2_155 DLMGTRLTELTFGAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLP
TH_1133|M.thermoresistible__bu DVMATRLTELTYDAPSRLEMMHGDAHPGNFMLLSDGRMGVIDFGAVAPLP
Mflv_4658|M.gilvum_PYR-GCK DLMATRLFEFCDDAPTRLEMVHGDAHPGNFMLLPGDKMGVIDFGAVAPMP
Mvan_1810|M.vanbaalenii_PYR-1 DLMATRLFEFCDDAPTRLEMVHGDAHPGNFMLMPDDKMGVIDFGAVAPMP
Mb3220|M.bovis_AF2122/97 DLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMP
Rv3197|M.tuberculosis_H37Rv DLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMP
MUL_2510|M.ulcerans_Agy99 DLMGTLLLELTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAPMP
MAV_4141|M.avium_104 DLMGTRLLELTFDAPRRLGMLHGDAHPGNFMLLPDGRMGVIDFGAVAPLP
MLBr_00640|M.leprae_Br4923 DRMGKLLLELTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLP
MMAR_1443|M.marinum_M NTWAEVIVRFVMGSFRHANLFHADPHPANFCFGADGTVGFVDFGSVAAVP
MAB_3315|M.abscessus_ATCC_1997 NVWVEAIWRFSTGSFRHANLFHADPHPGNYRFGLDGSVGFVDFGCIKVVP
: : .: .: : :.*.*.**.*: : .. :*.:***.: :*
MSMEG_1954|M.smegmatis_MC2_155 GGFPTSLGETIRLARDKNYDELLPTMERAGFLQKGQEVSIEEVEDMLRQY
TH_1133|M.thermoresistible__bu GGFPIELGLMLRYALEKDYDNLIATMEKAGFIQPGGEVSIREIDEMLRQY
Mflv_4658|M.gilvum_PYR-GCK GGWPIELGQMLRYAVDKNYDKLLPTMEKVGFIQKGQTVSTREIDDMLKQY
Mvan_1810|M.vanbaalenii_PYR-1 GGWPVELGQILRYAVDKNYEKLLPTMEKAGFIQKGQRPSTREIDDMLKQY
Mb3220|M.bovis_AF2122/97 GGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQY
Rv3197|M.tuberculosis_H37Rv GGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQY
MUL_2510|M.ulcerans_Agy99 GGYPIELGMTIRLARDKNYDLLLPTMEKAGLIQRGQQVSVREIDEMLRQY
MAV_4141|M.avium_104 DGLPVELGMTIRLARDKNYDLLLPTMEKAGFIQKGQQVSVRDIDDMLRQY
MLBr_00640|M.leprae_Br4923 GGFPVELGMSIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQY
MMAR_1443|M.marinum_M ECQRRNKVANVRATLDGRKRDVRELLVNMGFIARDSTLTADEAYAWMTEL
MAB_3315|M.abscessus_ATCC_1997 EPLRYRLVRMIRAAADERREDLRQLMVDAGYFAADSPLSSQDVFDWLGST
:* : : : : * : . : : : .
MSMEG_1954|M.smegmatis_MC2_155 VDPIKVDVFHYNRKWLQKMAASQMDNSVAQIKMARSLDLPANLAIPLRVI
TH_1133|M.thermoresistible__bu VEPVEVDVFHFNRKWLQRLTAVDMDRSVAQIKTARQMDLPRHLAIPMRVI
Mflv_4658|M.gilvum_PYR-GCK VEPLEVEVFHYTRRWLQKMTNIELEKAAGQIKAARQMDIPPKLAIPMRVI
Mvan_1810|M.vanbaalenii_PYR-1 VEPLEVPVFHYTRRWLQKMTAIELDKAAGQIKAARQMDIPPKLAIPMRVI
Mb3220|M.bovis_AF2122/97 VEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVI
Rv3197|M.tuberculosis_H37Rv VEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVI
MUL_2510|M.ulcerans_Agy99 VEPIQVEVFHYTRRWLQRMTVSQIDRSVAQIKAARQMDLPPKLAIPMRVI
MAV_4141|M.avium_104 VEPVEVEVFHYTRKWLQKMSAIEIDRSVSQIRTARQMDLPPKLVIPMRVI
MLBr_00640|M.leprae_Br4923 VEPIKVEVFHYTRKWLQQIS---LDRSVSHIKTARQLDLPATLALPMRVI
MMAR_1443|M.marinum_M VYELLVPQPVTYTHVASLRAIRALIDIRPPSHPFRRMSIPDDSVLFSRIN
MAB_3315|M.abscessus_ATCC_1997 VQDIRAPQPVTFTREVSTSATRSLLNFQT----LHQMSIPSDLVFLARIN
* : . : . : : : :.:* .: *:
MSMEG_1954|M.smegmatis_MC2_155 ASTVAICCQLDAHVPVKVIATELVPGFAEEAA------------------
TH_1133|M.thermoresistible__bu ASVVAISCQLDARVPVKALALEMIPGFAVEAA------------------
Mflv_4658|M.gilvum_PYR-GCK ASIVAISCQLDAHVPTRRIAMENVPGFADPDGV-----------------
Mvan_1810|M.vanbaalenii_PYR-1 ASIVAISCQLDAHVDTRRIAMEKVPGFADPDAV-----------------
Mb3220|M.bovis_AF2122/97 ASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV---------------
Rv3197|M.tuberculosis_H37Rv ASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV---------------
MUL_2510|M.ulcerans_Agy99 ASVAAILCQLDAHVPIKALSEELIPGFAEPDTAAV---------------
MAV_4141|M.avium_104 MSVAAILCQLDAHVPIKALSEELVPGFAEPDNAVV---------------
MLBr_00640|M.leprae_Br4923 ASVGAILCQLDAHVPTKALTEKLVPGFAEPDTAIV---------------
MMAR_1443|M.marinum_M LSMTAILAALGATIHARAIFDDMD-GVAEPITQLGKQHAAWVRKRGLPWG
MAB_3315|M.abscessus_ATCC_1997 LNISALSATLNATGHTRALLDDLD-GVGEPVSPLGRQHIAWVRDRGLPFG
. *: . *.* : : . *..
MSMEG_1954|M.smegmatis_MC2_155 -------
TH_1133|M.thermoresistible__bu -------
Mflv_4658|M.gilvum_PYR-GCK -------
Mvan_1810|M.vanbaalenii_PYR-1 -------
Mb3220|M.bovis_AF2122/97 -------
Rv3197|M.tuberculosis_H37Rv -------
MUL_2510|M.ulcerans_Agy99 -------
MAV_4141|M.avium_104 -------
MLBr_00640|M.leprae_Br4923 -------
MMAR_1443|M.marinum_M LDDHDHR
MAB_3315|M.abscessus_ATCC_1997 LDRHDHC