For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSDIKRGRAARNAKLASIPVGFAGRAAIGFGKRLTGKSRDEVQAELLEKAANQLFTVLGELKGGAMKVGQ ALSVLEAAVPEEFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGTKWRERFSSFDDTPVASASIGQVHK GVWSDGREVAVKIQYPGADEALRADLKTMQRLVGVFKQLAPGADVQGVVDELIERTEMELDYRLEAENQR AFAKAYQDHPHFAVPRIVASAPKVVIQEWMQGIPMAEIIRHGTTEQRDLMGTRLLELTFDAPRRLGMLHG DAHPGNFMLLPDGRMGVIDFGAVAPLPDGLPVELGMTIRLARDKNYDLLLPTMEKAGFIQKGQQVSVRDI DDMLRQYVEPVEVEVFHYTRKWLQKMSAIEIDRSVSQIRTARQMDLPPKLVIPMRVIMSVAAILCQLDAH VPIKALSEELVPGFAEPDNAVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4141 | - | - | 100% (442) | ABC1 family protein |
| M. avium 104 | MAV_4514 | - | 2e-27 | 27.70% (408) | ABC1 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3220 | - | 0.0 | 87.33% (442) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_4658 | - | 0.0 | 78.54% (438) | hypothetical protein Mflv_4658 |
| M. tuberculosis H37Rv | Rv3197 | - | 0.0 | 87.33% (442) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00640 | - | 0.0 | 81.45% (442) | hypothetical protein MLBr_00640 |
| M. abscessus ATCC 19977 | MAB_3504 | - | 1e-157 | 62.19% (439) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_1366 | - | 0.0 | 87.10% (442) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_1954 | - | 0.0 | 80.96% (436) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_1133 | - | 0.0 | 77.47% (435) | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. ulcerans Agy99 | MUL_2510 | - | 0.0 | 86.88% (442) | ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_1810 | - | 0.0 | 79.91% (438) | hypothetical protein Mvan_1810 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3220|M.bovis_AF2122/97 -----------------------------MDDGSVSDIKRGRAARNAKLA
Rv3197|M.tuberculosis_H37Rv -----------------------------MDDGSVSDIKRGRAARNAKLA
MMAR_1366|M.marinum_M -----------------------------MDDGGVSDIKRGRAARNAKLA
MUL_2510|M.ulcerans_Agy99 -----------------------------MDDGGVSDIKRGRAARNAKLA
MAV_4141|M.avium_104 ----------------------------------MSDIKRGRAARNAKLA
MLBr_00640|M.leprae_Br4923 MMRVKARMNNECSRLIIDCHITSMARFTVMDDRRVADIKRGQAARNAKLA
MSMEG_1954|M.smegmatis_MC2_155 ----------------------------------MSDIKRGSVARNAKLA
TH_1133|M.thermoresistible__bu -----------------------------VDDGVVADIKRGRVSRNAKLA
Mflv_4658|M.gilvum_PYR-GCK -----------------------------MDDGLVSEIKRGSVARNAKLA
Mvan_1810|M.vanbaalenii_PYR-1 -----------------------------MDDGLVSDIKRGRAARNAKLA
MAB_3504|M.abscessus_ATCC_1997 ----------------------------------MAEIRRGRAARAAKLA
:::*:** .:* ****
Mb3220|M.bovis_AF2122/97 SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
Rv3197|M.tuberculosis_H37Rv SIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAM
MMAR_1366|M.marinum_M SIPVGFAGRAALGVGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGGAM
MUL_2510|M.ulcerans_Agy99 SIPVGFAGRAALGVGKRLAGKSKDEVNAELMEKAANQLFTVLGELKGGAM
MAV_4141|M.avium_104 SIPVGFAGRAAIGFGKRLTGKSRDEVQAELLEKAANQLFTVLGELKGGAM
MLBr_00640|M.leprae_Br4923 SIPVGLAGRAVLGLGKRLTGKSKDEVNTKLIEKTAHQLFSVLGELKGGAM
MSMEG_1954|M.smegmatis_MC2_155 GLAGGMAGRAALGFGKRLTGKSKDEVTAELMDKAAQQLFTVLGELKGGAM
TH_1133|M.thermoresistible__bu GLGAGLAGRAALGLGKRLTGKSKDEVNAELMDKAAQQLFQVLGELKGGAM
Mflv_4658|M.gilvum_PYR-GCK SLPVGMAGRAALGFGKRLTGKSKDEVNAEMMDKAAQQLFTVLGELKGGAM
Mvan_1810|M.vanbaalenii_PYR-1 SLPVGMAGRAALGFGKRLTGKSKDEVNAELMDKAAQQLFTVLGELKGGAM
MAB_3504|M.abscessus_ATCC_1997 SLPAGIAGRAALGVGKRLTGKSKDEVNAEMMEKAAEQLFQVLGELKGAAM
.: *:****.:*.****:***:*** :::::*:*.*** *******.**
Mb3220|M.bovis_AF2122/97 KVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGT
Rv3197|M.tuberculosis_H37Rv KVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGT
MMAR_1366|M.marinum_M KVGQALSVMEAAIPEQFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
MUL_2510|M.ulcerans_Agy99 KVGQALSVMEAAIPEQFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
MAV_4141|M.avium_104 KVGQALSVLEAAVPEEFGEPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
MLBr_00640|M.leprae_Br4923 KVGQALSVMEAAIPEEYGEPYREALTKLQKDAPPLPVNKVHRVLDAQLGT
MSMEG_1954|M.smegmatis_MC2_155 KVGQALSVMEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQLGT
TH_1133|M.thermoresistible__bu KVGQALSVMEAAVPEQYGKPYREALTKLQKDAPPLPASRVHRVLDQQLGT
Mflv_4658|M.gilvum_PYR-GCK KVGQALSVMEAAIPEQYGKPYREALTKLQREAPPLPAAKVHRVLDQQLGT
Mvan_1810|M.vanbaalenii_PYR-1 KVGQALSVMEAAIPEQYGKPYREALTKLQREAPPLPAPKVHRVLDQQLGT
MAB_3504|M.abscessus_ATCC_1997 KLGQALSVFEAAIPPAFAEPFREALTKLQSDAPPLPADKVHRVLDAQLGT
*:******:***:* :.:*:******** :*****. :****** ****
Mb3220|M.bovis_AF2122/97 KWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADL
Rv3197|M.tuberculosis_H37Rv KWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADL
MMAR_1366|M.marinum_M KWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALKADL
MUL_2510|M.ulcerans_Agy99 KWRDRFGSFDDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALKADL
MAV_4141|M.avium_104 KWRERFSSFDDTPVASASIGQVHKGVWSDGREVAVKIQYPGADEALRADL
MLBr_00640|M.leprae_Br4923 KWRDRFSSFNDTPVASASIGQVHKAVWSYGREVAVKIQYPGADEALRADL
MSMEG_1954|M.smegmatis_MC2_155 KWRDRFSSFDDKPVASASIGQVHKGIWSDGREVAVKIQYPGADEALRADL
TH_1133|M.thermoresistible__bu RWRDRFRSFDDRPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADL
Mflv_4658|M.gilvum_PYR-GCK KWRERFQTFDDKAVASASIGQVHKAVWADGREVAVKIQYPGADEALRADL
Mvan_1810|M.vanbaalenii_PYR-1 KWRERFASFDDTAVASASIGQVHKAVWSDGREVAVKIQYPGADEALRADL
MAB_3504|M.abscessus_ATCC_1997 KWRERFQSFDDKPVASASIGQVHRAVWSDGRVVAVKVQYPGADEAVRSDL
:**:** :*:* .**********:.:*: ** ****:********:::**
Mb3220|M.bovis_AF2122/97 KTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAY
Rv3197|M.tuberculosis_H37Rv KTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAY
MMAR_1366|M.marinum_M KTMQRMVGVFKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
MUL_2510|M.ulcerans_Agy99 KTMQRMLGVFKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
MAV_4141|M.avium_104 KTMQRLVGVFKQLAPGADVQGVVDELIERTEMELDYRLEAENQRAFAKAY
MLBr_00640|M.leprae_Br4923 KTMQRMVGILKQLSPGADIQGVVDELVERTEMELDYRLEADNQRAFAKAY
MSMEG_1954|M.smegmatis_MC2_155 KTIQRLVGVFKQLAPGADIQGVVDELTERTEMELDYRLEADNQRAFAKAY
TH_1133|M.thermoresistible__bu KTMQRMVGILKQLSPGADVEGVVEELIERTEMELDYRLEADHQRAFAKAY
Mflv_4658|M.gilvum_PYR-GCK KTMQRMVGVLKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
Mvan_1810|M.vanbaalenii_PYR-1 KTMQRLVGVLKQLSPGADVQGVVDELIERTEMELDYRLEADNQRAFAKAY
MAB_3504|M.abscessus_ATCC_1997 KTMQRLSSLFKQIVPGADVKSIIDELIERTEEELDYRIEATNQRAFAKAF
**:**: .::**: ****::.:::** **** *****:** :*******:
Mb3220|M.bovis_AF2122/97 HDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAE
Rv3197|M.tuberculosis_H37Rv HDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAE
MMAR_1366|M.marinum_M AGHPRFLVPHIVASAPKVVIQEWIDGVPMSQIIRNGTQQERDLMGTLLLE
MUL_2510|M.ulcerans_Agy99 AGHPRFLVPHIVASAPKVVIQEWIDGVPMSQIIRNGTQQERDLMGTLLLE
MAV_4141|M.avium_104 QDHPHFAVPRIVASAPKVVIQEWMQGIPMAEIIRHGTTEQRDLMGTRLLE
MLBr_00640|M.leprae_Br4923 QGDPRFVVPNVVASAPKVIIQEWIDGVPMAEIIRNGTAQQRDRMGKLLLE
MSMEG_1954|M.smegmatis_MC2_155 RNDPHFAVPAIIASAPKVVISEWMEGIPMSVIIREGTPEQRDLMGTRLTE
TH_1133|M.thermoresistible__bu RDHPHFAVPQVIASAPKVVIAEWIDGIPMSQIIRDGTQEQRDVMATRLTE
Mflv_4658|M.gilvum_PYR-GCK AGHPEFVVPRVVASAPKVVIQEWIEGIPLSHIIREGTQEQRDLMATRLFE
Mvan_1810|M.vanbaalenii_PYR-1 AGDPHFVVPHVVASAPKVVIQEWIEGIPLSHIIRDGTQEQRDLMATRLFE
MAB_3504|M.abscessus_ATCC_1997 KGDPEFYVSPVVASAPKVVISEWMQGRKLSEIIGSGTEDERNECGRLLLK
..*.* *. ::******:* **::* :: ** ** ::*: . * :
Mb3220|M.bovis_AF2122/97 LTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGM
Rv3197|M.tuberculosis_H37Rv LTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGM
MMAR_1366|M.marinum_M LTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAPMPGGYPIELGM
MUL_2510|M.ulcerans_Agy99 LTFDAPRRLEMLHGDAHPGNFMLLPDGRMGVIDFGAVAPMPGGYPIELGM
MAV_4141|M.avium_104 LTFDAPRRLGMLHGDAHPGNFMLLPDGRMGVIDFGAVAPLPDGLPVELGM
MLBr_00640|M.leprae_Br4923 LTFDSPRRLEMLHGDAHPGNFMLLSDGRMGVIDFGAIAPLPGGFPVELGM
MSMEG_1954|M.smegmatis_MC2_155 LTFGAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLPGGFPTSLGE
TH_1133|M.thermoresistible__bu LTYDAPSRLEMMHGDAHPGNFMLLSDGRMGVIDFGAVAPLPGGFPIELGL
Mflv_4658|M.gilvum_PYR-GCK FCDDAPTRLEMVHGDAHPGNFMLLPGDKMGVIDFGAVAPMPGGWPIELGQ
Mvan_1810|M.vanbaalenii_PYR-1 FCDDAPTRLEMVHGDAHPGNFMLMPDDKMGVIDFGAVAPMPGGWPVELGQ
MAB_3504|M.abscessus_ATCC_1997 FTVSSPYRCGLLHADTHPGNFMLLPDGRLGVMDFGACATHEGGFPPNLGP
: .:* * ::*.*:*******:...::*::**** *. .* * .**
Mb3220|M.bovis_AF2122/97 TIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVF
Rv3197|M.tuberculosis_H37Rv TIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVF
MMAR_1366|M.marinum_M TIRLARDKNYDLLLPTMEKAGLIQRGQQVSVREIDEMLRQYVEPIQVEVF
MUL_2510|M.ulcerans_Agy99 TIRLARDKNYDLLLPTMEKAGLIQRGQQVSVREIDEMLRQYVEPIQVEVF
MAV_4141|M.avium_104 TIRLARDKNYDLLLPTMEKAGFIQKGQQVSVRDIDDMLRQYVEPVEVEVF
MLBr_00640|M.leprae_Br4923 SIRLARDKNYNLLLQTMEKAGLIQKGRQVSVRDIDEMMHQYVEPIKVEVF
MSMEG_1954|M.smegmatis_MC2_155 TIRLARDKNYDELLPTMERAGFLQKGQEVSIEEVEDMLRQYVDPIKVDVF
TH_1133|M.thermoresistible__bu MLRYALEKDYDNLIATMEKAGFIQPGGEVSIREIDEMLRQYVEPVEVDVF
Mflv_4658|M.gilvum_PYR-GCK MLRYAVDKNYDKLLPTMEKVGFIQKGQTVSTREIDDMLKQYVEPLEVEVF
Mvan_1810|M.vanbaalenii_PYR-1 ILRYAVDKNYEKLLPTMEKAGFIQKGQRPSTREIDDMLKQYVEPLEVPVF
MAB_3504|M.abscessus_ATCC_1997 IWRLERDGMWDELIPLMRAEGFIPPHTEVSPEEIDEYLKPFIDPLKSDEF
* : :: *: *. *:: * .:::: :: :::*:: *
Mb3220|M.bovis_AF2122/97 HYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQ
Rv3197|M.tuberculosis_H37Rv HYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQ
MMAR_1366|M.marinum_M HYTRRWLQRMTVSQIDRSVAQIKAARQMDLPPKLAIPMRVIASVAAILCQ
MUL_2510|M.ulcerans_Agy99 HYTRRWLQRMTVSQIDRSVAQIKAARQMDLPPKLAIPMRVIASVAAILCQ
MAV_4141|M.avium_104 HYTRKWLQKMSAIEIDRSVSQIRTARQMDLPPKLVIPMRVIMSVAAILCQ
MLBr_00640|M.leprae_Br4923 HYTRKWLQQIS---LDRSVSHIKTARQLDLPATLALPMRVIASVGAILCQ
MSMEG_1954|M.smegmatis_MC2_155 HYNRKWLQKMAASQMDNSVAQIKMARSLDLPANLAIPLRVIASTVAICCQ
TH_1133|M.thermoresistible__bu HFNRKWLQRLTAVDMDRSVAQIKTARQMDLPRHLAIPMRVIASVVAISCQ
Mflv_4658|M.gilvum_PYR-GCK HYTRRWLQKMTNIELEKAAGQIKAARQMDIPPKLAIPMRVIASIVAISCQ
Mvan_1810|M.vanbaalenii_PYR-1 HYTRRWLQKMTAIELDKAAGQIKAARQMDIPPKLAIPMRVIASIVAISCQ
MAB_3504|M.abscessus_ATCC_1997 HFTRKWMQRVAAKSSDVRGAQFQTGRHLDLPPVYLMMFRVLGSLSGILAQ
*:.*:*:*::: : .::: .* :*:* : :**: * .* .*
Mb3220|M.bovis_AF2122/97 LDAHVPIKALSEELIPGFAEPDAIVV--------
Rv3197|M.tuberculosis_H37Rv LDAHVPIKALSEELIPGFAEPDAIVV--------
MMAR_1366|M.marinum_M LDAHVPIKALSEELIPGFAEPDTAAV--------
MUL_2510|M.ulcerans_Agy99 LDAHVPIKALSEELIPGFAEPDTAAV--------
MAV_4141|M.avium_104 LDAHVPIKALSEELVPGFAEPDNAVV--------
MLBr_00640|M.leprae_Br4923 LDAHVPTKALTEKLVPGFAEPDTAIV--------
MSMEG_1954|M.smegmatis_MC2_155 LDAHVPVKVIATELVPGFAEEAA-----------
TH_1133|M.thermoresistible__bu LDARVPVKALALEMIPGFAVEAA-----------
Mflv_4658|M.gilvum_PYR-GCK LDAHVPTRRIAMENVPGFADPDGV----------
Mvan_1810|M.vanbaalenii_PYR-1 LDAHVDTRRIAMEKVPGFADPDAV----------
MAB_3504|M.abscessus_ATCC_1997 LDATIPYARIIGDWVPGFREDEDRMPVAPGGIRS
*** : : . :***