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MAAPATAPYPKTRRIRFWFGDPVPMRRHFADNDIALSHVLAGASAVFPPGEEFFVRSVRRYADRITEPTL KKRVAGFIGQEVTHGLHHRELNEKLTEMGYRSKMVENIGRRSGKVEDLVDKYLPNMDRLKYVRLTMLAAT AALEHYTAVLAERLLESSELQDMVTDDEVRNLLYWHAIEELEHKSVAFDVYRAVGGPEWLRRAVMAVIWT GTVPFATAGSWFSIAWSDPDGRRQPGRVLRETVGLIRGPLLNDGMIGRLAVYMKKDFHPDDLDTDALLDQ WRAELFGADGTLVDHLK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1116 | - | - | 100% (297) | hypothetical protein MAB_1116 |
| M. abscessus ATCC 19977 | MAB_4451c | - | 3e-94 | 56.90% (297) | hypothetical protein MAB_4451c |
| M. abscessus ATCC 19977 | MAB_2967c | - | 3e-80 | 51.70% (294) | hypothetical protein MAB_2967c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 3e-21 | 29.34% (259) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_4629 | - | 5e-53 | 41.10% (292) | metal-dependent hydrolase |
| M. tuberculosis H37Rv | Rv2777c | - | 3e-21 | 29.34% (259) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3143 | - | 4e-50 | 39.65% (285) | hypothetical protein MMAR_3143 |
| M. avium 104 | MAV_3671 | - | 2e-20 | 28.79% (257) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3675 | - | 2e-13 | 28.77% (219) | metal-dependent hydrolase |
| M. thermoresistible (build 8) | TH_1630 | - | 1e-11 | 29.35% (201) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2157 | - | 4e-21 | 30.83% (253) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_0314 | - | 2e-53 | 41.10% (292) | metal-dependent hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4629|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0314|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3143|M.marinum_M --------------------------------------------------
MAB_1116|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_3671|M.avium_104 --------------------------------------------------
MSMEG_3675|M.smegmatis_MC2_155 --------------------------------------------------
TH_1630|M.thermoresistible__bu --------------------------------------------------
Mflv_4629|M.gilvum_PYR-GCK ------------MSDDSSTRPTTRVVPKPRRVRFDMPAET-SRQHFVDGD
Mvan_0314|M.vanbaalenii_PYR-1 ------------MSDDSSTRPTTRVVPKPRRVRFDMPAGT-SRQHFVDGD
MMAR_3143|M.marinum_M ------------MPEDRAS-TKSRVLPKPRRVRFPMPTST-KRRHFVDGD
MAB_1116|M.abscessus_ATCC_1997 -----------------MAAPATAPYPKTRRIRFWFGDPVPMRRHFADND
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLP---FHYVPNE
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLP---FHYVPNE
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWANLP---FHYVPNE
MAV_3671|M.avium_104 -MVIIDNQAAGPHDAS---VDHERLVLEARDVDFDWAQLP---FHYAPGE
MSMEG_3675|M.smegmatis_MC2_155 --------MLRPLRFD-HEIDPGPVQIQARKVHFDLSDIP---LHWIPGH
TH_1630|M.thermoresistible__bu -----------------------MTELRIRRIRFDFDETVP--FNWNTAN
. * : * :: .
Mflv_4629|M.gilvum_PYR-GCK LVMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEAT
Mvan_0314|M.vanbaalenii_PYR-1 LVMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEAT
MMAR_3143|M.marinum_M LVMSHFISVLSATFPEGEDFFIRSVKYFQSSIDDPQLLTAVKGFIGQEAT
MAB_1116|M.abscessus_ATCC_1997 IALSHVLAGASAVFPPGEEFFVRSVRRYADRITEPTLKKRVAGFIGQEVT
Mb2799c|M.bovis_AF2122/97 PMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAM
Rv2777c|M.tuberculosis_H37Rv PMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAM
MUL_2157|M.ulcerans_Agy99 PLPTHVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAM
MAV_3671|M.avium_104 PFATHVLNVLHLLLPAGEQFFVEVFKQALPLIRDDQLRLDVQGFIGQEGV
MSMEG_3675|M.smegmatis_MC2_155 PVASTMVNLFNVVLPVAEHWFVDTFNEALPYVRDPKLADDMRGFIGQEAT
TH_1630|M.thermoresistible__bu PAFSTYMNMVSIMAICFEKMLVAAVREAMPLITDPAVAEEADAFLRQEAQ
: : *. :: .. : : : .*: **
Mflv_4629|M.gilvum_PYR-GCK HRHQHRLLNDRLQAMGYPTEGIDRHIKK--LVGRLEKRFSPKMR------
Mvan_0314|M.vanbaalenii_PYR-1 HRHQHRLLNDRLQAMGYPTEGIDRHIKK--LVGRLEKRFSPRMR------
MMAR_3143|M.marinum_M HRHQHRLLNERLQAMGYPTARIDRHVAR--LIKRLERRFSPEMR------
MAB_1116|M.abscessus_ATCC_1997 HGLHHRELNEKLTEMGYRSKMVENIGRRSGKVEDLVDKYLPNMDRLKYVR
Mb2799c|M.bovis_AF2122/97 HSQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWL
Rv2777c|M.tuberculosis_H37Rv HSQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWL
MUL_2157|M.ulcerans_Agy99 HSQAHSGVLAHFE-AQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWL
MAV_3671|M.avium_104 HSRAHANVLAHFA-ARGIDLRPYTGQIEWLFGTLLGPRPNWSPRRRQSWL
MSMEG_3675|M.smegmatis_MC2_155 HAETHDKVLEEFLTAHDVHYQPILELVDHVFNTMLAPKPATDPRRRLNDL
TH_1630|M.thermoresistible__bu HAGAHRRHVRALIRSHPGLQQTLDAAIG--AYDQLTETTSLRHR------
* * : *
Mflv_4629|M.gilvum_PYR-GCK ---LAVTAALEHYTATFAEIILTSDEAQELIGYTEVRPILLWHALEECEH
Mvan_0314|M.vanbaalenii_PYR-1 ---LAVTAALEHYTATFAEIILTSDEAQELIGDTEVRPILLWHALEECEH
MMAR_3143|M.marinum_M ---LSMTSALEHYTATLAEIILTSDDAQKLIGQTEVRPILLWHAFEESEH
MAB_1116|M.abscessus_ATCC_1997 LTMLAATAALEHYTAVLAERLLESSELQDMVTDDEVRNLLYWHAIEELEH
Mb2799c|M.bovis_AF2122/97 LEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEH
Rv2777c|M.tuberculosis_H37Rv LEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEH
MUL_2157|M.ulcerans_Agy99 LEQVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEH
MAV_3671|M.avium_104 LEQISLVSAIEHYTAILGEWILDSPAHDRIGTDPVMLDMLRWHGAEEVEH
MSMEG_3675|M.smegmatis_MC2_155 CDRLWLIAAIEHYTAVLGDFVLN-CAWDDHHADPTLTDLFRWHGAEEVEH
TH_1630|M.thermoresistible__bu ---LAYVADLEAAFTPFFTMLLDHEAALFRPGDDRVASLFVWHFVEEIEH
: : :* : : :* : :: ** ** **
Mflv_4629|M.gilvum_PYR-GCK KAVAFDVYETVGGSERTR------VWGMRIASLLLFTELVIQTTRSLAGD
Mvan_0314|M.vanbaalenii_PYR-1 KAVAFDVYETVGGSERTR------VWGMRIASLLLFSELVIQTTRSLAGD
MMAR_3143|M.marinum_M KAVAFDAYRLIGGTERTR------VRGMRIASAILFGELILQTALSMASD
MAB_1116|M.abscessus_ATCC_1997 KSVAFDVYRAVGGPEWLRR----AVMAVIWTGTVPFATAGSWFSIAWSDP
Mb2799c|M.bovis_AF2122/97 KAVAFDTMKHLRAGYWRQV----RAQLTVTPVMLLLWIRGVRFMYSVDPY
Rv2777c|M.tuberculosis_H37Rv KAVAFDTMKHLRAGYWRQV----RAQLTVTPVMLLLWIRGVRFMYSVDPY
MUL_2157|M.ulcerans_Agy99 KAVAFDTMKHLRAGYWRQV----RAQLAVTPVMLLLWIRGVRFMYTVDPL
MAV_3671|M.avium_104 KAVAFDTMKHLRAGYWRQV----RTQLVVTPAMLLLWIRGVRFMYSRDPY
MSMEG_3675|M.smegmatis_MC2_155 RSVAHDVAVYFQDSYLARV----RAMTIAATAVYMFFQRGTWAMIRKDPT
TH_1630|M.thermoresistible__bu RSSALLIYDAVVGDKWYRMRALPRIVRHLMHVVLLITNGINEHVPPADRA
:: * . : :
Mflv_4629|M.gilvum_PYR-GCK RAAYNPVRLLRSLRAFRHNPLFS------------RAAIERF--RSYTHA
Mvan_0314|M.vanbaalenii_PYR-1 RAAYNPVRLLRSLRAFRHNPLFS------------SAAIERF--RSYSRG
MMAR_3143|M.marinum_M KASYNPVTLVRSLRRFSRTPMFT------------ADALQRF--RSYNRP
MAB_1116|M.abscessus_ATCC_1997 DGRRQPGRVLRETVGLIRGPLLN------------DGMIGRL--AVYMKK
Mb2799c|M.bovis_AF2122/97 LPPGTKPRWRDYFKAARRGLVPG------------LPRLLRV-VGHYYKP
Rv2777c|M.tuberculosis_H37Rv LPPGTKPRWRDYFKAARRGLVPG------------LPRLLRV-VGHYYKP
MUL_2157|M.ulcerans_Agy99 LAPGTKPRWRDYVRSARRGLTPG------------PWRLIRV-VGDYYKP
MAV_3671|M.avium_104 LPPHTKPRWRDYFRAAWRGLVPG------------PLRFVRA-VANYYRP
MSMEG_3675|M.smegmatis_MC2_155 VDIGWWKMHRLRMRDSKLGLLPK------------FSTLFGTNTLAYCRP
TH_1630|M.thermoresistible__bu IDTSTIIPLYRLVHRTRKDPDMPGVRPALHPVPWRQKLLTAWRVLGSQTP
:
Mflv_4629|M.gilvum_PYR-GCK GFHPDDWDSAEILERWTKELFDADGGQQLRSNV-
Mvan_0314|M.vanbaalenii_PYR-1 GFHPDDWDSAEILECWTKELFDADGRQQARSSV-
MMAR_3143|M.marinum_M GFHPDDWDSTAVLERWSKELFDQDGSQKVIAQPG
MAB_1116|M.abscessus_ATCC_1997 DFHPDDLDTDALLDQWRAELFGADGTLVDHLK--
Mb2799c|M.bovis_AF2122/97 GFHPSQLGGLGAAVDYLAVSPAARASH-------
Rv2777c|M.tuberculosis_H37Rv GFHPSQLGGLGAAVDYLAVSPAARASH-------
MUL_2157|M.ulcerans_Agy99 GFHPSQLGGLERAVDYLAVSPAARASH-------
MAV_3671|M.avium_104 GFHPSQLGGLQRAVDYLAVSPAARASH-------
MSMEG_3675|M.smegmatis_MC2_155 SFTPDQMGSTAQAVAYLASSPAARAAHL------
TH_1630|M.thermoresistible__bu MHNPAHAVIPAFADDWIARYDRGDDVSHGYTS--
. * . :