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MQIAILAYPGMTALDAIGPYEMLRGLPSAEFRFVWHRPGPIVTDSGVLTLGATHSLTETPAPDMVLVGGS MPATLSTAADERVLDWLRKVHETTSWTASVCSGSLILGAAGILRGRDATCHWAGQRLLATFGANPQRDKR IVRDGKVITAAGVSAGLDLGLWLVGEIAGRPRAEATALCIEYDPQPPFNTGHMSKASTRNKADAVRVIKG LLSARDAGTELAAGSKMLWTNAIARIRSTDRSGHRHAPGPLRAGRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2900 | - | - | 100% (256) | hypothetical protein MAB_2900 |
| M. abscessus ATCC 19977 | MAB_0943 | - | 1e-75 | 58.82% (238) | hypothetical protein MAB_0943 |
| M. abscessus ATCC 19977 | MAB_2583c | - | 3e-18 | 31.41% (191) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0053 | - | 2e-33 | 44.83% (174) | hypothetical protein Mb0053 |
| M. gilvum PYR-GCK | Mflv_5266 | - | 4e-74 | 57.60% (250) | ThiJ/PfpI domain-containing protein |
| M. tuberculosis H37Rv | Rv0052 | - | 2e-33 | 44.83% (174) | hypothetical protein Rv0052 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2854 | - | 3e-75 | 58.26% (242) | hypothetical protein MMAR_2854 |
| M. avium 104 | MAV_2773 | - | 2e-71 | 56.20% (242) | DJ-1/PfpI family protein |
| M. smegmatis MC2 155 | MSMEG_1107 | - | 2e-71 | 57.08% (240) | isonitrile hydratase, putative |
| M. thermoresistible (build 8) | TH_3120 | - | 6e-12 | 31.36% (169) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_0070 | - | 3e-42 | 42.86% (210) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0973 | - | 5e-75 | 56.47% (255) | ThiJ/PfpI domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0053|M.bovis_AF2122/97 -----------------------------MPSFDVVFVGHRRGEVRSDNA
Rv0052|M.tuberculosis_H37Rv -----------------------------MPSFDVVFVGHRRGEVRSDNA
MUL_0070|M.ulcerans_Agy99 ----MQVAIPVFPRFTALDAVGPYEVLQRIPSIDVVFIGHQRGEVRTENG
Mflv_5266|M.gilvum_PYR-GCK ----MQVAIMLYPGFTALDFIGPYESLRWLPDTEVRFVWHEPGPIAADSH
Mvan_0973|M.vanbaalenii_PYR-1 ----MQVAIMLYPGFTALDFIGPYESLRWLPDVEVRFVWHEPGPIAADSH
MSMEG_1107|M.smegmatis_MC2_155 ----MQIAVVLYPTFTALDFIGPYEVLRNLPDAEVRFVWHEPGPVTADSG
MMAR_2854|M.marinum_M ---MPQFAFVAYPGFTALDMIGPYEVLRNLPHAEVRFVWHDPGPITADSG
MAV_2773|M.avium_104 ---MTQIAFLAYPGFTALDMIGPYEVLRNLPGAEVRFVWHETGPITADSG
MAB_2900|M.abscessus_ATCC_1997 ----MQIAILAYPGMTALDAIGPYEMLRGLPSAEFRFVWHRPGPIVTDSG
TH_3120|M.thermoresistible__bu VAALVLDGLAIFEFGVICEVFGVDRTDDGVPPVDFTVCGPRAGQPVRTSF
:* :. . * .
Mb0053|M.bovis_AF2122/97 MLGLLCDAAFDELTRPDVVIFPG-GIGTRTLIHDQTVLDWVREAHRHTLL
Rv0052|M.tuberculosis_H37Rv MLGLLCDAAFDELTRPDVVIFPG-GIGTRTLIHDQTVLDWVREAHRHTLL
MUL_0070|M.ulcerans_Agy99 MLGVTCDATFDEVDAPDVVAFPG-GIGTRGLLEDETIRGWLQAVHPHTRF
Mflv_5266|M.gilvum_PYR-GCK VLLVGATHSFDETPSPDVILIPG-GFATMEHARDEVVLAWVRRAHETSTW
Mvan_0973|M.vanbaalenii_PYR-1 VLLVGATHSFDETPSPDLILIPG-GFATMEHARDEKVLDWVRRAHRTSTW
MSMEG_1107|M.smegmatis_MC2_155 VLMVGATHTFDETPSPDVVLVPG-GPGSSAAARDERVLAWLRAVHPTANW
MMAR_2854|M.marinum_M VLVLGATHSLAETPAPDVVVVPG-GPATPVHARDEKLLDWLRQAHRSASW
MAV_2773|M.avium_104 VLVIGATHSLAETPSPDVVLVPG-GPGTAVHARDDALLDWLRTAHRTATW
MAB_2900|M.abscessus_ATCC_1997 VLTLGATHSLTETPAPDMVLVGGSMPATLSTAADERVLDWLRKVHETTSW
TH_3120|M.thermoresistible__bu GATLTPDSGLDGLAGADLVAIPA----IRQDDYLPEALDAVRAAADAGAI
: : .*:: . . :: .
Mb0053|M.bovis_AF2122/97 TTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFN-SLGARYVPQRVVEHLP
Rv0052|M.tuberculosis_H37Rv TTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFN-SLGARYVPQRVVEHLP
MUL_0070|M.ulcerans_Agy99 TTSVCTGALLLAAAGLLDGLTATTHWRAAELLN-GLGARYVPQRVVEHLP
Mflv_5266|M.gilvum_PYR-GCK TTSVCSGSVILAAAGVLDGKRATSHWAALPVLK-TLGAQPVGDQRIVEAD
Mvan_0973|M.vanbaalenii_PYR-1 TTSVCSGSVILAASGVLDGKRATSHWAALPVLK-TFGVQPVGDERVVVAD
MSMEG_1107|M.smegmatis_MC2_155 VASVCSGSMVLAAAGLLDGKRATSHWGALSALK-MCGVTAVSDERIVRAD
MMAR_2854|M.marinum_M TTSVCSGSVILAAAGLLKDRRATSHWLTIPALK-AFGAIPVADKRIVQQD
MAV_2773|M.avium_104 TTSVCTGSLILAAAGLLDGRRATSHWLTIPALK-AFGVTAVPDERIVHED
MAB_2900|M.abscessus_ATCC_1997 TASVCSGSLILGAAGILRGRDATCHWAGQRLLA-TFGANPQRDKRIVR-D
TH_3120|M.thermoresistible__bu ILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELARRYPTARVDRNVLYVDD
:**:*..: .*:*:* . .* ** : . . :
Mb0053|M.bovis_AF2122/97 ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQ---------
Rv0052|M.tuberculosis_H37Rv ERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQ---------
MUL_0070|M.ulcerans_Agy99 QRIITAAGVSSGIDMGLRLVELLVDREAAQVTQLLIEYDPE---------
Mflv_5266|M.gilvum_PYR-GCK AKTVTAAGVSAGIDLGLWLAGRIAGEEKAKAIQLSMEYDPQ---------
Mvan_0973|M.vanbaalenii_PYR-1 DKTVTAAGVSAGIDLGLWLAGQIAGESKAKAIQLSMEYDPQ---------
MSMEG_1107|M.smegmatis_MC2_155 DKVITAAGVSAGIDLGMWLAGQIAGEAKAKAIQLLIEYDPQ---------
MMAR_2854|M.marinum_M N-IITSAGVSAGLDLGLWLAGQIGGESRAKAIQLALEYDPQ---------
MAV_2773|M.avium_104 G-IVTSAGVSAGLDLALWLAAQIGGDGRAKAIQLALEYDPQ---------
MAB_2900|M.abscessus_ATCC_1997 GKVITAAGVSAGLDLGLWLVGEIAGRPRAEATALCIEYDPQ---------
TH_3120|M.thermoresistible__bu GDLITSAGTAAGIDACLHLVRRELGSEVTNTIARHMVVPPQRDGGQRQFI
:*:**.::*:* : *. . ::. : *:
Mb0053|M.bovis_AF2122/97 --------------------PPVDAGSLAKASPATHRLALEFYQHRL---
Rv0052|M.tuberculosis_H37Rv --------------------PPVDAGSLAKASPATHRLALEFYQHRL---
MUL_0070|M.ulcerans_Agy99 --------------------PPFDAGSLAKADEGVRARAIEFLDSRK---
Mflv_5266|M.gilvum_PYR-GCK --------------------PPFDSGHMSKASAGTKALATAMMGREMVRP
Mvan_0973|M.vanbaalenii_PYR-1 --------------------PPFDSGHMSKASASTKALATAMMGREMAKP
MSMEG_1107|M.smegmatis_MC2_155 --------------------PPFDAGHMSKASATTKAGATALLGRDMIKP
MMAR_2854|M.marinum_M --------------------PPFDSGHMSKASASTKVAATALLSKDSATP
MAV_2773|M.avium_104 --------------------PPFDSGHLSKASASTKAAATALLSRDSLSP
MAB_2900|M.abscessus_ATCC_1997 --------------------PPFNTGHMSKASTRNKADAVRVIKGLLSAR
TH_3120|M.thermoresistible__bu DQPIPVRHSEGFAPHLDWILSNLDKTHTVASLARRANMSPRTFARRFVEE
. .: : :
Mb0053|M.bovis_AF2122/97 --------------------------------------------------
Rv0052|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0070|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5266|M.gilvum_PYR-GCK AA---LAASTGLLWDAALKRIRRAKRRQ-----GSLSAP-----------
Mvan_0973|M.vanbaalenii_PYR-1 AA---LAASTGLLWDAALKRIRARRSRPE---PAKLRGGS----------
MSMEG_1107|M.smegmatis_MC2_155 EP---LKASVLLAWDQAIRRVRGR---------GAARRTA----------
MMAR_2854|M.marinum_M VN---LKAATMLAWQQALAAARARRRKR-----QPVDSTP----------
MAV_2773|M.avium_104 TY---LKATALLAWDQALDRVRSRRRRR-----QPDLSPA----------
MAB_2900|M.abscessus_ATCC_1997 DAGTELAAGSKMLWTNAIARIRSTDRSGHRHAPGPLRAGRG---------
TH_3120|M.thermoresistible__bu TGRTPMQWVTDQRVLYARRLLEETDLDIHRIAARCGFGSTTLLRHHFRRV
Mb0053|M.bovis_AF2122/97 ------------------------------
Rv0052|M.tuberculosis_H37Rv ------------------------------
MUL_0070|M.ulcerans_Agy99 ------------------------------
Mflv_5266|M.gilvum_PYR-GCK ------------------------------
Mvan_0973|M.vanbaalenii_PYR-1 ------------------------------
MSMEG_1107|M.smegmatis_MC2_155 ------------------------------
MMAR_2854|M.marinum_M ------------------------------
MAV_2773|M.avium_104 ------------------------------
MAB_2900|M.abscessus_ATCC_1997 ------------------------------
TH_3120|M.thermoresistible__bu IGVTPSDYRRRFACGSTTSGSTESGAEVTD