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LLGSTVIASAVAATAGFTGGYVSSGHDTNITGGELPAPENVGDAKTIGLLLFDGVEELDFAGPWEVFGAW AADFPQDKYKPVSISLASRQVRCAQGLDVVAQHTYEAAPPIDVLLVPGGKGWRTLVDQPESIAKIQKLTE RVELVASVCTGALLLAKAGFLKNRRATTHWSALDTLTQLDSTIIVDRNSRYVDGGNYVTSSGVSAGVDMA LYVVSKLGGPSRANDVAHALQYTHQWQL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2583c | - | - | 100% (239) | AraC family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4754 | - | 1e-25 | 37.37% (190) | AraC family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0943 | - | 2e-20 | 31.09% (193) | hypothetical protein MAB_0943 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0053 | - | 3e-14 | 33.87% (124) | hypothetical protein Mb0053 |
| M. gilvum PYR-GCK | Mflv_1008 | - | 3e-24 | 35.86% (198) | Fis family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0052 | - | 3e-14 | 33.87% (124) | hypothetical protein Rv0052 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2855 | - | 3e-20 | 32.45% (188) | transcriptional regulatory protein |
| M. avium 104 | MAV_2773 | - | 9e-22 | 34.21% (190) | DJ-1/PfpI family protein |
| M. smegmatis MC2 155 | MSMEG_3365 | - | 3e-23 | 34.76% (187) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 4e-18 | 29.73% (185) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 4e-20 | 32.45% (188) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5828 | - | 3e-24 | 37.89% (190) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1008|M.gilvum_PYR-GCK --------------------------------MTDEFRHNADPGGKTVVF
Mvan_5828|M.vanbaalenii_PYR-1 ------------------------------------MSIPTDGRSRHIAM
MMAR_2855|M.marinum_M -------------------------------------------MARKVVI
MUL_2902|M.ulcerans_Agy99 -------------------------------------------MARKVVT
MSMEG_3365|M.smegmatis_MC2_155 ---------------------------MGYVSLTTLPARLKLDDMKAVAV
TH_3120|M.thermoresistible__bu -----------------------------------------------VAA
Mb0053|M.bovis_AF2122/97 --------------------------------------------------
Rv0052|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2773|M.avium_104 --------------------------------------------MTQIAF
MAB_2583c|M.abscessus_ATCC_199 MLLGSTVIASAVAATAGFTGGYVSSGHDTNITGGELPAPENVGDAKTIGL
Mflv_1008|M.gilvum_PYR-GCK ALYDKVTLQDVAAPMEIFARANDFGA-------SYRVLTVSPSGRPVGTT
Mvan_5828|M.vanbaalenii_PYR-1 VVFDGVRTLDLTGPLEVFDVAQALGC-------RYSIGLYSSSG-ATSVR
MMAR_2855|M.marinum_M VGFPGVQPLDVVGPFEVFAGASLLSE------GGYDVALASIDERPVAT-
MUL_2902|M.ulcerans_Agy99 VGFPGVQPLDVVGPFEVFAGASLLSE------GGYDVALASIDERPVAT-
MSMEG_3365|M.smegmatis_MC2_155 VGFSGVQALDVVGPFETFTCASRFVDDETWQLEGYEVMLASVDGQPVPA-
TH_3120|M.thermoresistible__bu LVLDGLAIFEFGVICEVFGVDRTDDG------VPPVDFTVCGPRAGQPVR
Mb0053|M.bovis_AF2122/97 --------------------MPSFDV------------VFVGHRRGEVRS
Rv0052|M.tuberculosis_H37Rv --------------------MPSFDV------------VFVGHRRGEVRS
MAV_2773|M.avium_104 LAYPGFTALDMIGPYEVLRNLPGAEV------------RFVWHETGPITA
MAB_2583c|M.abscessus_ATCC_199 LLFDGVEELDFAGPWEVFGAWAADFP-------QDKYKPVSISLASRQVR
Mflv_1008|M.gilvum_PYR-GCK AFATLNVDVA-LDAAPDAFDTLLVPGGVPADFSFTPGLHDIPEEPTPDSV
Mvan_5828|M.vanbaalenii_PYR-1 CSSGLSIDAAPASVAASEVDTLLVPGGE----CLVAG--GVP--------
MMAR_2855|M.marinum_M -GIGLEFMTTRLPDPSAPVDTVVLPGGG--------GVDAARDN------
MUL_2902|M.ulcerans_Agy99 -GIGLEFMTTRLPDPSAPVDTVVLPGGG--------GVDAARDN------
MSMEG_3365|M.smegmatis_MC2_155 -STGLGLMACPLPDP-EQVDTVVIPGGV--------GVRQAAAD------
TH_3120|M.thermoresistible__bu TSFGATLTPDSGLDGLAGADLVAIPAIR-------------QDD----YL
Mb0053|M.bovis_AF2122/97 DNAMLGLLCDAAFDELTRPDVVIFPGGI--------GTRTLIHD------
Rv0052|M.tuberculosis_H37Rv DNAMLGLLCDAAFDELTRPDVVIFPGGI--------GTRTLIHD------
MAV_2773|M.avium_104 DSGVLVIGATHSLAETPSPDVVLVPGGP--------GTAVHARD------
MAB_2583c|M.abscessus_ATCC_199 CAQGLDVVAQHTYEAAPPIDVLLVPGGK--------GWRTLVDQ------
. * : .*.
Mflv_1008|M.gilvum_PYR-GCK ADACDMVRRLAPRARRIASVCTGSFVLAALGLLDGRRATTHWAHCQTLAR
Mvan_5828|M.vanbaalenii_PYR-1 AHLRRAIRALAPGARRIASICAGSFALAAAGVLDGRRATTHWRHLDTFAR
MMAR_2855|M.marinum_M VALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAR
MUL_2902|M.ulcerans_Agy99 VALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAR
MSMEG_3365|M.smegmatis_MC2_155 PALMTWFREAAEHARRIVSVCTGAFLVAEAGLLNGCQATTHWAFADELAQ
TH_3120|M.thermoresistible__bu PEALDAVRAAADAGAIILTVCSGAFLAGAAGLLDGRPCTTHWGLTEELAR
Mb0053|M.bovis_AF2122/97 QTVLDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFN-
Rv0052|M.tuberculosis_H37Rv QTVLDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLFN-
MAV_2773|M.avium_104 DALLDWLRTAHRTATWTTSVCTGSLILAAAGLLDGRRATSHWLTIPALK-
MAB_2583c|M.abscessus_ATCC_199 PESIAKIQKLTERVELVASVCTGALLLAKAGFLKNRRATTHWSALDTLTQ
.: ::*:* : . *.*.. .*:** :
Mflv_1008|M.gilvum_PYR-GCK QYPAVMVDPDSLFVQDGP-FITGAGITAGIDLALAMVESDFGPAVARRVA
Mvan_5828|M.vanbaalenii_PYR-1 RYPSTRVERESVYTRDGE-TWTSSGGTAGIDLALALVGDDFGAAVAQEIS
MMAR_2855|M.marinum_M EFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVA
MUL_2902|M.ulcerans_Agy99 EFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVA
MSMEG_3365|M.smegmatis_MC2_155 RYPEVRVDPNPMFVRSSRQVWTAAGVSAGIDLALALVEDDHSTEVAKAVA
TH_3120|M.thermoresistible__bu RYPTARVDRNVLYVDDGD-LITSAGTAAGIDACLHLVRRELGSEVTNTIA
Mb0053|M.bovis_AF2122/97 -SLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVELLVSREAAEASQ
Rv0052|M.tuberculosis_H37Rv -SLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVELLVSREAAEASQ
MAV_2773|M.avium_104 -AFGVTAVPDERIVHEDG-IVTSAGVSAGLDLALWLAAQIGGDGRAKAIQ
MAB_2583c|M.abscessus_ATCC_199 LDSTIIVDRNSRYVDGGN-YVTSSGVSAGVDMALYVVSKLGGPSRANDVA
: *.:* ::*:* * :. . :.
Mflv_1008|M.gilvum_PYR-GCK RWMVVFLQRPGGQAQFSVWAESALPVTGGLRAVVDSVIADPAGDHSLAAM
Mvan_5828|M.vanbaalenii_PYR-1 KEMVVLGRRMEGHPQISAAARTPRPKHPELERLMATVVVNPAGHYELETV
MMAR_2855|M.marinum_M RWLVLYLRRPGGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEEL
MUL_2902|M.ulcerans_Agy99 RWLVLYLRRPCGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEEL
MSMEG_3365|M.smegmatis_MC2_155 RWLVLSLRRPGGQAQFAAPIWTPRARRDEIRLVQEVIEANPAAPHTIDTL
TH_3120|M.thermoresistible__bu RHMVVPPQRDGGQRQFIDQPIPVR-HSEGFAPHLDWILSNLDKTHTVASL
Mb0053|M.bovis_AF2122/97 LMIEYDPQPPVDAGSLAKASP---------------------ATHRLALE
Rv0052|M.tuberculosis_H37Rv LMIEYDPQPPVDAGSLAKASP---------------------ATHRLALE
MAV_2773|M.avium_104 LALEYDPQPPFDSGHLSKASASTKAAATALLSRDSLSPTYLKATALLAWD
MAB_2583c|M.abscessus_ATCC_199 HALQYTHQWQL---------------------------------------
: :
Mflv_1008|M.gilvum_PYR-GCK ASRAAVSERHLVRVFRDQVGMTPARFVEQARLEAAKVLLATGDHSQDSVA
Mvan_5828|M.vanbaalenii_PYR-1 AAQLGLSPRHLARLFKAQVGVTLREYVNEVRLENAVALVLAG-ESFHAAA
MMAR_2855|M.marinum_M AHRAAMSPRHFTRVFTGEVGEAPRQYVERVRTEAARRQLEETEDTVVAIA
MUL_2902|M.ulcerans_Agy99 AHRAAMSPRHFTRVFTGEVGEAPGRYVERVRTEAARRQLEETEDTVVAIA
MSMEG_3365|M.smegmatis_MC2_155 ATSAAMSTRHFTRVFTSEVGEGPGRYVDRVRTQAARRQLEETTDTVAAIA
TH_3120|M.thermoresistible__bu ARRANMSPRTFARRFVEETGRTPMQWVTDQRVLYARRLLEETDLDIHRIA
Mb0053|M.bovis_AF2122/97 FYQHRL--------------------------------------------
Rv0052|M.tuberculosis_H37Rv FYQHRL--------------------------------------------
MAV_2773|M.avium_104 QALDRVRSRRRRRQPDLSPA------------------------------
MAB_2583c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1008|M.gilvum_PYR-GCK RRSGFGTPDTMRRTFRRNLGISPGVYRNRFRTTGVDA-----------
Mvan_5828|M.vanbaalenii_PYR-1 QRSGLRSGARVRDHL---------IAR---RTPA--------------
MMAR_2855|M.marinum_M ARCGFGTAETMRRNFIRRVGISPDQYRKAFA-----------------
MUL_2902|M.ulcerans_Agy99 ARCGFGTAETMRRNFIRRVGISPDQYRKAFA-----------------
MSMEG_3365|M.smegmatis_MC2_155 ARCGFGTPETMRRNFIRLLGVSPEAYRKAFN-----------------
TH_3120|M.thermoresistible__bu ARCGFGSTTLLRHHFRRVIGVTPSDYRRRFACGSTTSGSTESGAEVTD
Mb0053|M.bovis_AF2122/97 ------------------------------------------------
Rv0052|M.tuberculosis_H37Rv ------------------------------------------------
MAV_2773|M.avium_104 ------------------------------------------------
MAB_2583c|M.abscessus_ATCC_199 ------------------------------------------------