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MGDHEHPSRERDRVLDAVRLMSLATVVAYHVLAGSPTLVKGKPAMASNYNVHWLFWLVPLMPLFFFAGAA ANVHSWESGKSWGQFLMGRATRLFRPVFYFLAVVALITTLLRITMGNSPQLLYLEMRHIELLWYVGAYLL TLAFMPCLARIRTAHQLGWFIAAMCLLTALTDTVSLITDTWLTTGWINMIFMWLIPAALGIGYQRRLVPR PVALTLASVALAATVALAVLGPYPSGLIANMPPTLLLAASSIVECLAVIAFAPIINRWVQGARTWRFFEL CNSGSMTIYLWHWVVTFLLSYGVYLTFRIGLLSQHDAWYWPANVLRLLIVCAVVAVFFVPLRATERRPLP WWDRPVPAMNTGRDIAVGVLVLVGAILTLVYTRIYVIDPHWGGFTPIGRWIVVASLVPLAAARFLCRNPL SPTAGQVMDGRPLAHSAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2825 | - | - | 100% (438) | hypothetical protein MAB_2825 |
| M. abscessus ATCC 19977 | MAB_1297c | - | 3e-62 | 36.54% (416) | hypothetical protein MAB_1297c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2705c | - | 5e-05 | 24.55% (224) | antibiotic ABC transporter transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3453 | - | 2e-61 | 34.75% (423) | hypothetical protein Mflv_3453 |
| M. tuberculosis H37Rv | Rv2686c | - | 5e-05 | 24.55% (224) | antibiotic ABC transporter transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0218 | - | 4e-62 | 35.98% (428) | hypothetical protein MMAR_0218 |
| M. avium 104 | MAV_4113 | - | 1e-62 | 37.59% (439) | hypothetical protein MAV_4113 |
| M. smegmatis MC2 155 | MSMEG_5168 | - | 1e-64 | 36.51% (430) | hypothetical protein MSMEG_5168 |
| M. thermoresistible (build 8) | TH_0475 | - | 4e-23 | 40.85% (142) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3178 | - | 2e-57 | 34.70% (415) | hypothetical protein MUL_3178 |
| M. vanbaalenii PYR-1 | Mvan_4565 | - | 6e-65 | 37.04% (432) | hypothetical protein Mvan_4565 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5168|M.smegmatis_MC2_155 ---MTVFPSPAEVAASTPHDRDRAIDVIRIVSLVGVVLGHTIMATSTIRD
TH_0475|M.thermoresistible__bu ----MNFPSPAEVAVATPATRDRAIDVIRIVSLLGVVAGHTLMATSTLRD
Mvan_4565|M.vanbaalenii_PYR-1 MSAAALFPRPAEVEAATPPDRDRAIDVIRIVALVGVVVGHTVMATSIIRD
MMAR_0218|M.marinum_M MTSLTGFPGPAELAERTPADRDRAIDVIRITALVGVVVGHTVMATSVIRG
MAV_4113|M.avium_104 ----MRFPDAAEVAARTPADRDRVLDVIRIVSLGGVVLGHTVMAASIIRD
Mflv_3453|M.gilvum_PYR-GCK ------------MTQST---RDRAVDVIRLAALVVVMFGHCALLLATIDS
MUL_3178|M.ulcerans_Agy99 MRKTSLTPDPAALARSTPPGRVRAVDVARLWALVVVMFGHRALLLATIDS
MAB_2825|M.abscessus_ATCC_1997 ----------MGDHEHPSRERDRVLDAVRLMSLATVVAYHVLAGSPTLVK
Mb2705c|M.bovis_AF2122/97 ---------------------------MRAISSLAGPRALAAFGRNDIRG
Rv2686c|M.tuberculosis_H37Rv ---------------------------MRAISSLAGPRALAAFGRNDIRG
* : :
MSMEG_5168|M.smegmatis_MC2_155 DVFIWSNLLTASPVFQALTWVFQIMPLFFFAGVAACVQSWR---PGTAWG
TH_0475|M.thermoresistible__bu DVFIWQNLLTASPILQALTWVFQIMPLFFFAGVAASVSGWA---PGSSWG
Mvan_4565|M.vanbaalenii_PYR-1 DVFIWTNLLTASPVFQALTWLFQIMPLFFFAGVAASVQSWR---PGASWG
MMAR_0218|M.marinum_M GVLRWDNLLTTSTTFQALTWIFQIMPLFFFAGAAACVPSWR---PGTNWG
MAV_4113|M.avium_104 HVLIWDNLLTTSALFQAMTWLLQIMPLFFFAGAAACVSSWT---PGTDWG
Mflv_3453|M.gilvum_PYR-GCK GGVRIANLIGEVPAVAPATWVVQVMPLFFLAGGAAGVHSYH---TGTPWG
MUL_3178|M.ulcerans_Agy99 HGVRIGNLLGELPALTPLTWLVQVMPLFFMAGGAAGAYGWHPTEPAVPWG
MAB_2825|M.abscessus_ATCC_1997 G----KPAMASNYNVHWLFWLVPLMPLFFFAGAAANVHSWE---SGKSWG
Mb2705c|M.bovis_AF2122/97 TYR------------DPLLVMLVIAPVIWTTGVALLTPLFT---------
Rv2686c|M.tuberculosis_H37Rv TYR------------DPLLVMLVIAPVIWTTGVALLTPLFT---------
:. : *::: :* * . :
MSMEG_5168|M.smegmatis_MC2_155 GWLLRRCTRLYRPVFYYLAFWTATLVVLRAILP-VHVYEPIAGISTQLLW
TH_0475|M.thermoresistible__bu DWLLRRCTRLYRPVFYYLGFWTVALVVLRCLVP-VDVYRPIAGISIQLLW
Mvan_4565|M.vanbaalenii_PYR-1 NWLMRRCTRLYRPVFYYLAFWAVALVVLRLLLP-VHVYEPVAGISVQLLW
MMAR_0218|M.marinum_M GWLMKRAARLFRPVFYYLSFWAVALVIFYPLLP-QHVYEPVAGVSIQLLW
MAV_4113|M.avium_104 GWLMRRCTRLFRPVFYYLAFWAVTLTVLYQALP-QHIYEPIAGVSTQLLW
Mflv_3453|M.gilvum_PYR-GCK AWLFRRAQRLCRPVFWYLAVWAAVLAAARVVLG-ADSAVRLGGESVALLW
MUL_3178|M.ulcerans_Agy99 AWLLTRAQRLCRPVFWYLAAWTGALVVVRATLG-AQSAAGLGRECVALLW
MAB_2825|M.abscessus_ATCC_1997 QFLMGRATRLFRPVFYFLAVVALITTLLRITMGNSPQLLYLEMRHIELLW
Mb2705c|M.bovis_AF2122/97 EMLARRYG----------------------------------------FD
Rv2686c|M.tuberculosis_H37Rv EMLARRYG----------------------------------------FD
* * :
MSMEG_5168|M.smegmatis_MC2_155 FLGAYVLVLAAVPLLARITTTGRLAAAVLGTYVFIAAVDTVRINADGYAT
TH_0475|M.thermoresistible__bu FLGAYVLVLAAGPXXX-----GR--GAVRGSAA-----------------
Mvan_4565|M.vanbaalenii_PYR-1 FLGAYVLVLAAVPALAHISTTGRLVGAVAATYGVVAIVDVIRINTDVWPV
MMAR_0218|M.marinum_M FLGAYVLVLAAMPVLSRITSTARLAASVTAVYAMIAAVDAVRLHCSAAPS
MAV_4113|M.avium_104 FLGAYVLVLAAMPVLYRITTTGRLAAGVAAVYGAIALIDVIRLHWPALMP
Mflv_3453|M.gilvum_PYR-GCK FLGVYLVALAFVPALVRLRSGRAVAGVLAALLVVAASTDALRFATGDEAA
MUL_3178|M.ulcerans_Agy99 FLGVYLVVLAFVPALTRVRTGYGIATVSVTLLVLAAAVDQIRLAVGTAES
MAB_2825|M.abscessus_ATCC_1997 YVGAYLLTLAFMPCLARIRTAHQLGWFIAAMCLLTALTDTVSLITDTWLT
Mb2705c|M.bovis_AF2122/97 LVGYYPLILTAFLLLTSIIVAGALAAFLVLDDVDAGTMTALRVTP-----
Rv2686c|M.tuberculosis_H37Rv LVGYYPLILTAFLLLTSIIVAGALAAFLVLDDVDAGTMTALRVTP-----
:* * : *:
MSMEG_5168|M.smegmatis_MC2_155 LGYL-NTVVWLIPGMLGVAYRRRLLSARAALRIGLVMLSVNLALLYFGPY
TH_0475|M.thermoresistible__bu --------------------------------------------------
Mvan_4565|M.vanbaalenii_PYR-1 FGYL-NLTMWLIPGMFGVAYRRGLLSSGAALAPGAALFTVNVALVTLGPY
MMAR_0218|M.marinum_M LGYL-NLAVWLIPAMFGVAYRRRLLTRARAIGTAAILLATNVALLCWGPY
MAV_4113|M.avium_104 LGYL-NLAVWLIPAMFGAAYRRGLLGGRAALAVAAAFFAADVALVRWGPY
Mflv_3453|M.gilvum_PYR-GCK GLTN-FVIVWLIPVVIGVGYAQRLIGRRAAAVGAAAAFTTAWALVVFGPY
MUL_3178|M.ulcerans_Agy99 GAAN-FLIVWLIPVALGVGYARRLIGPRAALVAAVDAFAAQLRLVGTGVY
MAB_2825|M.abscessus_ATCC_1997 TGWINMIFMWLIPAALGIGYQRRLVPRPVALTLASVALAATVALAVLGPY
Mb2705c|M.bovis_AF2122/97 -----------VPLSVFFGYR-------AATVMVVTTIYVVATMSCSGIL
Rv2686c|M.tuberculosis_H37Rv -----------VPLSVFFGYR-------AATVMVVTTIYVVATMSCSGIL
MSMEG_5168|M.smegmatis_MC2_155 ELSLVGIETQQLKNMTPPSLLLAGHAIMLCAFAIALAPAITRWAQRPRVW
TH_0475|M.thermoresistible__bu --------------------------------------------------
Mvan_4565|M.vanbaalenii_PYR-1 ELSLVGIESQQLKNMSPPSLLLAGHAIMMCALAIAAAPGISRWARRPRVW
MMAR_0218|M.marinum_M ELSLVGIEGQRLPNMSPPSLLLAGHAIILSALAVVAAPAIARWARRPRVW
MAV_4113|M.avium_104 QLSMVGTGDHHLSNTSPPSLLLAGHAIILSALAIAAAPAIARWAQRPRVW
Mflv_3453|M.gilvum_PYR-GCK EVSLVVTGAERISNVSPPTLLLAMHCVWMSCVFVVAAAAIGRWARRPRVW
MUL_3178|M.ulcerans_Agy99 DVSLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRRWAGRPRVW
MAB_2825|M.abscessus_ATCC_1997 PSGLIAN--------MPPTLLLAASSIVECLAVIAFAPIINRWVQGARTW
Mb2705c|M.bovis_AF2122/97 EPGLVSS-------LIPIGLVAGLSAVVTLLLILAVANNKIQGLAMVRAL
Rv2686c|M.tuberculosis_H37Rv EPGLVSS-------LIPIGLVAGLSAVVTLLLILAVANNKIQGLAMVRAL
MSMEG_5168|M.smegmatis_MC2_155 WLAVIGNSGAMTLYLWHMPLLLGMHLVFDYAG-FDRYDPASPGFVALSVV
TH_0475|M.thermoresistible__bu --------------------------------------------------
Mvan_4565|M.vanbaalenii_PYR-1 WLTAIGNSGAMTLYLWHIPLLLGMHLTFDYLG-HPRFDPAAPDFVALSVL
MMAR_0218|M.marinum_M WLAAIGNSGAMTLYLWHMPALLGVHLLFDGLG-APRY-PGEPGFAVISAA
MAV_4113|M.avium_104 WWTAIGNSGAMTLYLWHMPVLLGVHLAFDYLG-CPRF-PGAPDFLAISVA
Mflv_3453|M.gilvum_PYR-GCK RVVAAGNAGAMTLYLWHIVAIAIAAFGLHAVG-LQAYDVAAPDLWAQLLV
MUL_3178|M.ulcerans_Agy99 QLVAMGNGGAMTLYLWHIPAIAVAAFVLHAVG-LDAFDVHTPWFWCLLAL
MAB_2825|M.abscessus_ATCC_1997 RFFELCNSGSMTIYLWHWVVTFLLSYGVYLTFRIGLLSQHDAWYWPANVL
Mb2705c|M.bovis_AF2122/97 GMLIAG-LPCLPWFISSNWNLAFGVLPPYWAAKAFWVASDHGTWWPYLVG
Rv2686c|M.tuberculosis_H37Rv GMLIAG-LPCLPWFISSNWNLAFGVLPPYWAAKAFWVASDHGTWWPYLVG
MSMEG_5168|M.smegmatis_MC2_155 QMVLMTALVGIAFVALRPLENNPLPLWDGGSVPTPGMRSLTVGLLLCTAG
TH_0475|M.thermoresistible__bu --------------------------------------------------
Mvan_4565|M.vanbaalenii_PYR-1 QLVLMALAVAAAFTVLRPLENDPLPLWDGGFVAHPGPRSAAVGALLCVAG
MMAR_0218|M.marinum_M QLLIMCGAVAALFVALRPLENNPLPGWDGAPAITSVWRGAGVGVLLCVAG
MAV_4113|M.avium_104 QVLLVVVAVAVLFVALRPLENNPLSGWDGAPAVMSRGWGAAVGALLCVAG
Mflv_3453|M.gilvum_PYR-GCK RTLVFAVVMLILFRLLSPLERRPLPWWDG-AVTESGPRAIGAGALVCAAG
MUL_3178|M.ulcerans_Agy99 RAVVFTLVMAATFWLLSPLEHRRLPWWDE-PVPVVGTRASASGLLVCGAR
MAB_2825|M.abscessus_ATCC_1997 RLLIVCAVVAVFFVPLRATERRPLPWWDRPVPAMNTGRDIAVGVLVLVGA
Mb2705c|M.bovis_AF2122/97 GAVYNLAIVWVLFRRFRAKHA-----------------------------
Rv2686c|M.tuberculosis_H37Rv GAVYNLAIVWVLFRRFRAKHA-----------------------------
MSMEG_5168|M.smegmatis_MC2_155 AATLASV-------AWGLKDQ-GVYCVVVMIAALVLARWLANPAAIRSAA
TH_0475|M.thermoresistible__bu --------------------------------------------------
Mvan_4565|M.vanbaalenii_PYR-1 AATLASV-------GWGLKEQ-GLYCVAATVTALVAARALANDGQL----
MMAR_0218|M.marinum_M AAILASV-------KWGLKDD-GLACIAVTVAALVAARILAVARLPR---
MAV_4113|M.avium_104 VALLAAI-------RWGLKDD-GLVCMAVVVAALVAARIVAQHAGPAGHG
Mflv_3453|M.gilvum_PYR-GCK VALVLTA-------KFGLGESAGWAACAGFVAAVVAARFCARVAPHDLGP
MUL_3178|M.ulcerans_Agy99 VALLLVA-------KNGLSGAPGWVSLGCFLVALVAARAMT-GPPSGAGE
MAB_2825|M.abscessus_ATCC_1997 ILTLVYTRIYVIDPHWGGFTPIGRWIVVASLVPLAAARFLCRNPLSPTAG
Mb2705c|M.bovis_AF2122/97 --------------------------------------------------
Rv2686c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5168|M.smegmatis_MC2_155 VELA-----------------
TH_0475|M.thermoresistible__bu ---------------------
Mvan_4565|M.vanbaalenii_PYR-1 ---------------------
MMAR_0218|M.marinum_M ---------------------
MAV_4113|M.avium_104 SSSRPCSMA------------
Mflv_3453|M.gilvum_PYR-GCK DVRSPSESPENENLEHIASNS
MUL_3178|M.ulcerans_Agy99 AQRAPAAVRQRVG--------
MAB_2825|M.abscessus_ATCC_1997 QVMDGRPLAHSAR--------
Mb2705c|M.bovis_AF2122/97 ---------------------
Rv2686c|M.tuberculosis_H37Rv ---------------------