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M. thermoresistible (build 8) TH_0475 (-)

annotation: conserved hypothetical protein
coordinates: 1012175 - 1012681
length: 169

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0475--100% (169)conserved hypothetical protein
M. thermoresistible (build 8)TH_0209-5e-2145.87% (109) conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3453-1e-3044.06% (143) hypothetical protein Mflv_3453
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1297c-2e-6470.97% (155) hypothetical protein MAB_1297c
M. marinum MMMAR_0218-8e-6068.63% (153) hypothetical protein MMAR_0218
M. avium 104MAV_4113-3e-6068.39% (155) hypothetical protein MAV_4113
M. smegmatis MC2 155MSMEG_5168-1e-7181.70% (153) hypothetical protein MSMEG_5168
M. ulcerans Agy99MUL_3178-5e-3145.16% (155) hypothetical protein MUL_3178
M. vanbaalenii PYR-1Mvan_4565-3e-7180.39% (153) hypothetical protein Mvan_4565

CLUSTAL 2.0.9 multiple sequence alignment


TH_0475|M.thermoresistible__bu      ----MNFPSPAEVAVATPATRDRAIDVIRIVSLLGVVAGHTLMATSTLRD
MSMEG_5168|M.smegmatis_MC2_155      ---MTVFPSPAEVAASTPHDRDRAIDVIRIVSLVGVVLGHTIMATSTIRD
Mvan_4565|M.vanbaalenii_PYR-1       MSAAALFPRPAEVEAATPPDRDRAIDVIRIVALVGVVVGHTVMATSIIRD
MAB_1297c|M.abscessus_ATCC_199      MTMTLGLPTADEVGAATPATRDRALDVIRIVSLAGVVLGHTIMAVSTIDN
MMAR_0218|M.marinum_M               MTSLTGFPGPAELAERTPADRDRAIDVIRITALVGVVVGHTVMATSVIRG
MAV_4113|M.avium_104                ----MRFPDAAEVAARTPADRDRVLDVIRIVSLGGVVLGHTVMAASIIRD
Mflv_3453|M.gilvum_PYR-GCK          ------------MTQST---RDRAVDVIRLAALVVVMFGHCALLLATIDS
MUL_3178|M.ulcerans_Agy99           MRKTSLTPDPAALARSTPPGRVRAVDVARLWALVVVMFGHRALLLATIDS
                                                :   *   * *.:** *: :*  *: **  :  : : .

TH_0475|M.thermoresistible__bu      DVFIWQNLLTASPILQALTWVFQIMPLFFFAGVAASVSGWA---PGSSWG
MSMEG_5168|M.smegmatis_MC2_155      DVFIWSNLLTASPVFQALTWVFQIMPLFFFAGVAACVQSWR---PGTAWG
Mvan_4565|M.vanbaalenii_PYR-1       DVFIWTNLLTASPVFQALTWLFQIMPLFFFAGVAASVQSWR---PGASWG
MAB_1297c|M.abscessus_ATCC_199      GVLLWGNLLNGRPVFQALTWVFQIMPLFFFAGVAASVGSWK---PGTSWG
MMAR_0218|M.marinum_M               GVLRWDNLLTTSTTFQALTWIFQIMPLFFFAGAAACVPSWR---PGTNWG
MAV_4113|M.avium_104                HVLIWDNLLTTSALFQAMTWLLQIMPLFFFAGAAACVSSWT---PGTDWG
Mflv_3453|M.gilvum_PYR-GCK          GGVRIANLIGEVPAVAPATWVVQVMPLFFLAGGAAGVHSYH---TGTPWG
MUL_3178|M.ulcerans_Agy99           HGVRIGNLLGELPALTPLTWLVQVMPLFFMAGGAAGAYGWHPTEPAVPWG
                                      .   **:   . . . **:.*:*****:** ** . .:    ..  **

TH_0475|M.thermoresistible__bu      DWLLRRCTRLYRPVFYYLGFWTVALVVLRCLVPVDVYRPIAGISIQLLWF
MSMEG_5168|M.smegmatis_MC2_155      GWLLRRCTRLYRPVFYYLAFWTATLVVLRAILPVHVYEPIAGISTQLLWF
Mvan_4565|M.vanbaalenii_PYR-1       NWLMRRCTRLYRPVFYYLAFWAVALVVLRLLLPVHVYEPVAGISVQLLWF
MAB_1297c|M.abscessus_ATCC_199      SWLMHRCTRLYRPVFYYLGFWAVALLILRQILPLHVYEPVAGVSTQLLWF
MMAR_0218|M.marinum_M               GWLMKRAARLFRPVFYYLSFWAVALVIFYPLLPQHVYEPVAGVSIQLLWF
MAV_4113|M.avium_104                GWLMRRCTRLFRPVFYYLAFWAVTLTVLYQALPQHIYEPIAGVSTQLLWF
Mflv_3453|M.gilvum_PYR-GCK          AWLFRRAQRLCRPVFWYLAVWAAVLAAARVVLGADSAVRLGGESVALLWF
MUL_3178|M.ulcerans_Agy99           AWLLTRAQRLCRPVFWYLAAWTGALVVVRATLGAQSAAGLGRECVALLWF
                                     **: *. ** ****:**. *: .*      :  .    :.  .  ****

TH_0475|M.thermoresistible__bu      LGAYVLVLAAGPXXX-----GR--GAVRGSAA------------------
MSMEG_5168|M.smegmatis_MC2_155      LGAYVLVLAAVPLLARITTTGRLAAAVLGTYVFIAAVDTVRINADGYATL
Mvan_4565|M.vanbaalenii_PYR-1       LGAYVLVLAAVPALAHISTTGRLVGAVAATYGVVAIVDVIRINTDVWPVF
MAB_1297c|M.abscessus_ATCC_199      LGAYVLVLAAIPLLARITTTRAMFTALAAVYLGIAAIDVLRLGLDAPKGI
MMAR_0218|M.marinum_M               LGAYVLVLAAMPVLSRITSTARLAASVTAVYAMIAAVDAVRLHCSAAPSL
MAV_4113|M.avium_104                LGAYVLVLAAMPVLYRITTTGRLAAGVAAVYGAIALIDVIRLHWPALMPL
Mflv_3453|M.gilvum_PYR-GCK          LGVYLVALAFVPALVRLRSGRAVAGVLAALLVVAASTDALRFATGDEAAG
MUL_3178|M.ulcerans_Agy99           LGVYLVVLAFVPALTRVRTGYGIATVSVTLLVLAAAVDQIRLAVGTAESG
                                    **.*::.**  *                                      

TH_0475|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5168|M.smegmatis_MC2_155      GYLNTVVWLIPGMLGVAYRRRLLSARAALRIGLVMLSVNLALLYFGPYEL
Mvan_4565|M.vanbaalenii_PYR-1       GYLNLTMWLIPGMFGVAYRRGLLSSGAALAPGAALFTVNVALVTLGPYEL
MAB_1297c|M.abscessus_ATCC_199      GYVNFVVWLLPAVLGVGYRRQLITQRAALVLAATVFAINVALVTFGPYTI
MMAR_0218|M.marinum_M               GYLNLAVWLIPAMFGVAYRRRLLTRARAIGTAAILLATNVALLCWGPYEL
MAV_4113|M.avium_104                GYLNLAVWLIPAMFGAAYRRGLLGGRAALAVAAAFFAADVALVRWGPYQL
Mflv_3453|M.gilvum_PYR-GCK          LTNFVIVWLIPVVIGVGYAQRLIGRRAAAVGAAAAFTTAWALVVFGPYEV
MUL_3178|M.ulcerans_Agy99           AANFLIVWLIPVALGVGYARRLIGPRAALVAAVDAFAAQLRLVGTGVYDV
                                                                                      

TH_0475|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5168|M.smegmatis_MC2_155      SLVGIETQQLKNMTPPSLLLAGHAIMLCAFAIALAPAITRWAQRPRVWWL
Mvan_4565|M.vanbaalenii_PYR-1       SLVGIESQQLKNMSPPSLLLAGHAIMMCALAIAAAPGISRWARRPRVWWL
MAB_1297c|M.abscessus_ATCC_199      SLVGVAGQKVPNMIPPSLVLAGHAIILSALASAAMPAINRWAQRPRVWWA
MMAR_0218|M.marinum_M               SLVGIEGQRLPNMSPPSLLLAGHAIILSALAVVAAPAIARWARRPRVWWL
MAV_4113|M.avium_104                SMVGTGDHHLSNTSPPSLLLAGHAIILSALAIAAAPAIARWAQRPRVWWW
Mflv_3453|M.gilvum_PYR-GCK          SLVVTGAERISNVSPPTLLLAMHCVWMSCVFVVAAAAIGRWARRPRVWRV
MUL_3178|M.ulcerans_Agy99           SLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRRWAGRPRVWQL
                                                                                      

TH_0475|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5168|M.smegmatis_MC2_155      AVIGNSGAMTLYLWHMPLLLGMHLVFDYAGFDRYDPASPGFVALSVVQMV
Mvan_4565|M.vanbaalenii_PYR-1       TAIGNSGAMTLYLWHIPLLLGMHLTFDYLGHPRFDPAAPDFVALSVLQLV
MAB_1297c|M.abscessus_ATCC_199      VAIGNSGAMTLYLWHMPALLGMHLAFDFLGFDRYDTTAPDFIALSVLQVA
MMAR_0218|M.marinum_M               AAIGNSGAMTLYLWHMPALLGVHLLFDGLGAPRYP-GEPGFAVISAAQLL
MAV_4113|M.avium_104                TAIGNSGAMTLYLWHMPVLLGVHLAFDYLGCPRFP-GAPDFLAISVAQVL
Mflv_3453|M.gilvum_PYR-GCK          VAAGNAGAMTLYLWHIVAIAIAAFGLHAVGLQAYDVAAPDLWAQLLVRTL
MUL_3178|M.ulcerans_Agy99           VAMGNGGAMTLYLWHIPAIAVAAFVLHAVGLDAFDVHTPWFWCLLALRAV
                                                                                      

TH_0475|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5168|M.smegmatis_MC2_155      LMTALVGIAFVALRPLENNPLPLWDGGSVPTPGMRSLTVGLLLCTAGAAT
Mvan_4565|M.vanbaalenii_PYR-1       LMALAVAAAFTVLRPLENDPLPLWDGGFVAHPGPRSAAVGALLCVAGAAT
MAB_1297c|M.abscessus_ATCC_199      TMMLLVTGLFLALRPLENNPLPGWDGGYIARPGARSAAAGTALMLAGGFT
MMAR_0218|M.marinum_M               IMCGAVAALFVALRPLENNPLPGWDGAPAITSVWRGAGVGVLLCVAGAAI
MAV_4113|M.avium_104                LVVVAVAVLFVALRPLENNPLSGWDGAPAVMSRGWGAAVGALLCVAGVAL
Mflv_3453|M.gilvum_PYR-GCK          VFAVVMLILFRLLSPLERRPLPWWDGA-VTESGPRAIGAGALVCAAGVAL
MUL_3178|M.ulcerans_Agy99           VFTLVMAATFWLLSPLEHRRLPWWDEP-VPVVGTRASASGLLVCGARVAL
                                                                                      

TH_0475|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5168|M.smegmatis_MC2_155      LASVAWGLKDQ-GVYCVVVMIAALVLARWLANPAAIRSAAVELA------
Mvan_4565|M.vanbaalenii_PYR-1       LASVGWGLKEQ-GLYCVAATVTALVAARALANDGQL--------------
MAB_1297c|M.abscessus_ATCC_199      LASVVWGLKGF-GLVCWVVVLAGLILARVLANRTKI--------------
MMAR_0218|M.marinum_M               LASVKWGLKDD-GLACIAVTVAALVAARILAVARLPR-------------
MAV_4113|M.avium_104                LAAIRWGLKDD-GLVCMAVVVAALVAARIVAQHAGPAGHGSSSRPCSMA-
Mflv_3453|M.gilvum_PYR-GCK          VLTAKFGLGESAGWAACAGFVAAVVAARFCARVAPHDLGPDVRSPSESPE
MUL_3178|M.ulcerans_Agy99           LLVAKNGLSGAPGWVSLGCFLVALVAARAMT-GPPSGAGEAQRAPAAVRQ
                                                                                      

TH_0475|M.thermoresistible__bu      -----------
MSMEG_5168|M.smegmatis_MC2_155      -----------
Mvan_4565|M.vanbaalenii_PYR-1       -----------
MAB_1297c|M.abscessus_ATCC_199      -----------
MMAR_0218|M.marinum_M               -----------
MAV_4113|M.avium_104                -----------
Mflv_3453|M.gilvum_PYR-GCK          NENLEHIASNS
MUL_3178|M.ulcerans_Agy99           RVG--------