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MSAAALFPRPAEVEAATPPDRDRAIDVIRIVALVGVVVGHTVMATSIIRDDVFIWTNLLTASPVFQALTW LFQIMPLFFFAGVAASVQSWRPGASWGNWLMRRCTRLYRPVFYYLAFWAVALVVLRLLLPVHVYEPVAGI SVQLLWFLGAYVLVLAAVPALAHISTTGRLVGAVAATYGVVAIVDVIRINTDVWPVFGYLNLTMWLIPGM FGVAYRRGLLSSGAALAPGAALFTVNVALVTLGPYELSLVGIESQQLKNMSPPSLLLAGHAIMMCALAIA AAPGISRWARRPRVWWLTAIGNSGAMTLYLWHIPLLLGMHLTFDYLGHPRFDPAAPDFVALSVLQLVLMA LAVAAAFTVLRPLENDPLPLWDGGFVAHPGPRSAAVGALLCVAGAATLASVGWGLKEQGLYCVAATVTAL VAARALANDGQL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4565 | - | - | 100% (432) | hypothetical protein Mvan_4565 |
| M. vanbaalenii PYR-1 | Mvan_3210 | - | 1e-82 | 42.26% (407) | hypothetical protein Mvan_3210 |
| M. vanbaalenii PYR-1 | Mvan_3490 | - | 4e-32 | 28.54% (424) | hypothetical protein Mvan_3490 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3453 | - | 2e-87 | 43.83% (413) | hypothetical protein Mflv_3453 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1297c | - | 1e-161 | 64.37% (421) | hypothetical protein MAB_1297c |
| M. marinum M | MMAR_0218 | - | 1e-165 | 66.98% (427) | hypothetical protein MMAR_0218 |
| M. avium 104 | MAV_4113 | - | 1e-165 | 67.70% (421) | hypothetical protein MAV_4113 |
| M. smegmatis MC2 155 | MSMEG_5168 | - | 0.0 | 74.94% (423) | hypothetical protein MSMEG_5168 |
| M. thermoresistible (build 8) | TH_0457 | - | 5e-82 | 74.49% (196) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3178 | - | 1e-79 | 42.69% (431) | hypothetical protein MUL_3178 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4565|M.vanbaalenii_PYR-1 MSAAALFPRPAEVEAATPPDRDRAIDVIRIVALVGVVVGHTVMATSIIRD
MSMEG_5168|M.smegmatis_MC2_155 ---MTVFPSPAEVAASTPHDRDRAIDVIRIVSLVGVVLGHTIMATSTIRD
TH_0457|M.thermoresistible__bu --------------------------------------------------
MMAR_0218|M.marinum_M MTSLTGFPGPAELAERTPADRDRAIDVIRITALVGVVVGHTVMATSVIRG
MAV_4113|M.avium_104 ----MRFPDAAEVAARTPADRDRVLDVIRIVSLGGVVLGHTVMAASIIRD
MAB_1297c|M.abscessus_ATCC_199 MTMTLGLPTADEVGAATPATRDRALDVIRIVSLAGVVLGHTIMAVSTIDN
Mflv_3453|M.gilvum_PYR-GCK ------------MTQST---RDRAVDVIRLAALVVVMFGHCALLLATIDS
MUL_3178|M.ulcerans_Agy99 MRKTSLTPDPAALARSTPPGRVRAVDVARLWALVVVMFGHRALLLATIDS
Mvan_4565|M.vanbaalenii_PYR-1 DVFIWTNLLTASPVFQALTWLFQIMPLFFFAGVAASVQSWR---PGASWG
MSMEG_5168|M.smegmatis_MC2_155 DVFIWSNLLTASPVFQALTWVFQIMPLFFFAGVAACVQSWR---PGTAWG
TH_0457|M.thermoresistible__bu --------------------------------------------------
MMAR_0218|M.marinum_M GVLRWDNLLTTSTTFQALTWIFQIMPLFFFAGAAACVPSWR---PGTNWG
MAV_4113|M.avium_104 HVLIWDNLLTTSALFQAMTWLLQIMPLFFFAGAAACVSSWT---PGTDWG
MAB_1297c|M.abscessus_ATCC_199 GVLLWGNLLNGRPVFQALTWVFQIMPLFFFAGVAASVGSWK---PGTSWG
Mflv_3453|M.gilvum_PYR-GCK GGVRIANLIGEVPAVAPATWVVQVMPLFFLAGGAAGVHSYH---TGTPWG
MUL_3178|M.ulcerans_Agy99 HGVRIGNLLGELPALTPLTWLVQVMPLFFMAGGAAGAYGWHPTEPAVPWG
Mvan_4565|M.vanbaalenii_PYR-1 NWLMRRCTRLYRPVFYYLAFWAVALVVLRLLLPVHVYEPVAGISVQLLWF
MSMEG_5168|M.smegmatis_MC2_155 GWLLRRCTRLYRPVFYYLAFWTATLVVLRAILPVHVYEPIAGISTQLLWF
TH_0457|M.thermoresistible__bu --------------------------------------------------
MMAR_0218|M.marinum_M GWLMKRAARLFRPVFYYLSFWAVALVIFYPLLPQHVYEPVAGVSIQLLWF
MAV_4113|M.avium_104 GWLMRRCTRLFRPVFYYLAFWAVTLTVLYQALPQHIYEPIAGVSTQLLWF
MAB_1297c|M.abscessus_ATCC_199 SWLMHRCTRLYRPVFYYLGFWAVALLILRQILPLHVYEPVAGVSTQLLWF
Mflv_3453|M.gilvum_PYR-GCK AWLFRRAQRLCRPVFWYLAVWAAVLAAARVVLGADSAVRLGGESVALLWF
MUL_3178|M.ulcerans_Agy99 AWLLTRAQRLCRPVFWYLAAWTGALVVVRATLGAQSAAGLGRECVALLWF
Mvan_4565|M.vanbaalenii_PYR-1 LGAYVLVLAAVPALAHISTTGRLVGAVAATYGVVAIVDVIRINTDVWPVF
MSMEG_5168|M.smegmatis_MC2_155 LGAYVLVLAAVPLLARITTTGRLAAAVLGTYVFIAAVDTVRINADGYATL
TH_0457|M.thermoresistible__bu --------------------------------------------------
MMAR_0218|M.marinum_M LGAYVLVLAAMPVLSRITSTARLAASVTAVYAMIAAVDAVRLHCSAAPSL
MAV_4113|M.avium_104 LGAYVLVLAAMPVLYRITTTGRLAAGVAAVYGAIALIDVIRLHWPALMPL
MAB_1297c|M.abscessus_ATCC_199 LGAYVLVLAAIPLLARITTTRAMFTALAAVYLGIAAIDVLRLGLDAPKGI
Mflv_3453|M.gilvum_PYR-GCK LGVYLVALAFVPALVRLRSGRAVAGVLAALLVVAASTDALRFATGDEAAG
MUL_3178|M.ulcerans_Agy99 LGVYLVVLAFVPALTRVRTGYGIATVSVTLLVLAAAVDQIRLAVGTAESG
Mvan_4565|M.vanbaalenii_PYR-1 GYLNLTMWLIPGMFGVAYRRGLLSSGAALAPGAALFTVNVALVTLGPYEL
MSMEG_5168|M.smegmatis_MC2_155 GYLNTVVWLIPGMLGVAYRRRLLSARAALRIGLVMLSVNLALLYFGPYEL
TH_0457|M.thermoresistible__bu ----------------------------------MLAVNLGLVAFGPYEV
MMAR_0218|M.marinum_M GYLNLAVWLIPAMFGVAYRRRLLTRARAIGTAAILLATNVALLCWGPYEL
MAV_4113|M.avium_104 GYLNLAVWLIPAMFGAAYRRGLLGGRAALAVAAAFFAADVALVRWGPYQL
MAB_1297c|M.abscessus_ATCC_199 GYVNFVVWLLPAVLGVGYRRQLITQRAALVLAATVFAINVALVTFGPYTI
Mflv_3453|M.gilvum_PYR-GCK LTNFVIVWLIPVVIGVGYAQRLIGRRAAAVGAAAAFTTAWALVVFGPYEV
MUL_3178|M.ulcerans_Agy99 AANFLIVWLIPVALGVGYARRLIGPRAALVAAVDAFAAQLRLVGTGVYDV
:: *: * * :
Mvan_4565|M.vanbaalenii_PYR-1 SLVGIESQQLKNMSPPSLLLAGHAIMMCALAIAAAPGISRWARRPRVWWL
MSMEG_5168|M.smegmatis_MC2_155 SLVGIETQQLKNMTPPSLLLAGHAIMLCAFAIALAPAITRWAQRPRVWWL
TH_0457|M.thermoresistible__bu SLVGIETQQLKNMFPPSLLLAGHAIMMCAFAIAAAPAIARWARRPRVWWL
MMAR_0218|M.marinum_M SLVGIEGQRLPNMSPPSLLLAGHAIILSALAVVAAPAIARWARRPRVWWL
MAV_4113|M.avium_104 SMVGTGDHHLSNTSPPSLLLAGHAIILSALAIAAAPAIARWAQRPRVWWW
MAB_1297c|M.abscessus_ATCC_199 SLVGVAGQKVPNMIPPSLVLAGHAIILSALASAAMPAINRWAQRPRVWWA
Mflv_3453|M.gilvum_PYR-GCK SLVVTGAERISNVSPPTLLLAMHCVWMSCVFVVAAAAIGRWARRPRVWRV
MUL_3178|M.ulcerans_Agy99 SLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRRWAGRPRVWQL
*:* .:: * **:*:** *. :.. . . * *** *****
Mvan_4565|M.vanbaalenii_PYR-1 TAIGNSGAMTLYLWHIPLLLGMHLTFDYLGHPRFDPAAPDFVALSVLQLV
MSMEG_5168|M.smegmatis_MC2_155 AVIGNSGAMTLYLWHMPLLLGMHLVFDYAGFDRYDPASPGFVALSVVQMV
TH_0457|M.thermoresistible__bu TVLGNSGAMTLYLWHMPPLLLMHLAFDYLGWDRIDPSAPDFVVISVVQAG
MMAR_0218|M.marinum_M AAIGNSGAMTLYLWHMPALLGVHLLFDGLGAPRYPG-EPGFAVISAAQLL
MAV_4113|M.avium_104 TAIGNSGAMTLYLWHMPVLLGVHLAFDYLGCPRFPG-APDFLAISVAQVL
MAB_1297c|M.abscessus_ATCC_199 VAIGNSGAMTLYLWHMPALLGMHLAFDFLGFDRYDTTAPDFIALSVLQVA
Mflv_3453|M.gilvum_PYR-GCK VAAGNAGAMTLYLWHIVAIAIAAFGLHAVGLQAYDVAAPDLWAQLLVRTL
MUL_3178|M.ulcerans_Agy99 VAMGNGGAMTLYLWHIPAIAVAAFVLHAVGLDAFDVHTPWFWCLLALRAV
.. **.*********: : : :. * * : :
Mvan_4565|M.vanbaalenii_PYR-1 LMALAVAAAFTVLRPLENDPLPLWDGGFVAHPGPRSAAVGALLCVAGAAT
MSMEG_5168|M.smegmatis_MC2_155 LMTALVGIAFVALRPLENNPLPLWDGGSVPTPGMRSLTVGLLLCTAGAAT
TH_0457|M.thermoresistible__bu IMAAAVAALFVLLRPLESNPLPGWDGGAVTAPGLRSAAVGTLLCIAGAAT
MMAR_0218|M.marinum_M IMCGAVAALFVALRPLENNPLPGWDGAPAITSVWRGAGVGVLLCVAGAAI
MAV_4113|M.avium_104 LVVVAVAVLFVALRPLENNPLSGWDGAPAVMSRGWGAAVGALLCVAGVAL
MAB_1297c|M.abscessus_ATCC_199 TMMLLVTGLFLALRPLENNPLPGWDGGYIARPGARSAAAGTALMLAGGFT
Mflv_3453|M.gilvum_PYR-GCK VFAVVMLILFRLLSPLERRPLPWWDG-AVTESGPRAIGAGALVCAAGVAL
MUL_3178|M.ulcerans_Agy99 VFTLVMAATFWLLSPLEHRRLPWWDE-PVPVVGTRASASGLLVCGARVAL
. : * * *** *. ** . * : *
Mvan_4565|M.vanbaalenii_PYR-1 LASVGWGLKEQ-GLYCVAATVTALVAARALANDGQL--------------
MSMEG_5168|M.smegmatis_MC2_155 LASVAWGLKDQ-GVYCVVVMIAALVLARWLANPAAIRSAAVELA------
TH_0457|M.thermoresistible__bu LASVGWGLKDT-GLVCVAVLLAALVAARTLAAPARQPR------------
MMAR_0218|M.marinum_M LASVKWGLKDD-GLACIAVTVAALVAARILAVARLPR-------------
MAV_4113|M.avium_104 LAAIRWGLKDD-GLVCMAVVVAALVAARIVAQHAGPAGHGSSSRPCSMA-
MAB_1297c|M.abscessus_ATCC_199 LASVVWGLKGF-GLVCWVVVLAGLILARVLANRTKI--------------
Mflv_3453|M.gilvum_PYR-GCK VLTAKFGLGESAGWAACAGFVAAVVAARFCARVAPHDLGPDVRSPSESPE
MUL_3178|M.ulcerans_Agy99 LLVAKNGLSGAPGWVSLGCFLVALVAARAMT-GPPSGAGEAQRAPAAVRQ
: ** * . :..:: ** :
Mvan_4565|M.vanbaalenii_PYR-1 -----------
MSMEG_5168|M.smegmatis_MC2_155 -----------
TH_0457|M.thermoresistible__bu -----------
MMAR_0218|M.marinum_M -----------
MAV_4113|M.avium_104 -----------
MAB_1297c|M.abscessus_ATCC_199 -----------
Mflv_3453|M.gilvum_PYR-GCK NENLEHIASNS
MUL_3178|M.ulcerans_Agy99 RVG--------